Effect of periodontal treatment on glycated hemoglobin and metabolic syndrome parameters: a randomized clinical trial.

alexandrossfakianakis shared this article with you from Inoreader Effect of periodontal treatment on glycated hemoglobin and metabolic syndrome parameters: a randomized clinical trial. via Journal of Clinical Periodontology Abstract Aim to assess the effect of periodontal treatment on HbA1c and diagnostic parameters of patients with Metabolic Syndrome (MetS). Material and Methods A hundred and fifty-eight patients with MetS, and moderate and severe periodontitis were included. They were randomized into a test group (n=79), which received non-surgical periodontal treatment, and a control group (n=79), which received no treatment. Medical treatment was delivered to both groups. Clinical periodontal, anthropometric, and serological parameters were assessed at baseline, 3 and 6 months. The main outcome was glycated hemoglobin (HbA1c) levels, and the secondary outcomes were changes in the MetS parameters, C-reactive protein and HOMA indexes. Results Significant reductions in all the periodontal parameters were observed in the test group, compared with the control group, at 3 and 6 months (p<0.001). HbA1c levels, MetS parameters, C-reactive protein and HOMA indexes showed no significant differences between the test group and the control group at 3 and 6 months. Conclusion(s) periodontal treatment led to a substantial reduction in periodontal inflammation, although there was no significant effect on the parameters used for MetS diagnosis in patients with early-diagnosed and well-controlled MetS. Registration number NCT02012842, www.clinicaltrials.gov. This article is protected by copyright. All rights reserved. View on Web

Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.