Clinical characteristics, outcomes, and seasonality of acute respiratory infection associated with single and co‐detected rhinovirus species among hospitalized children in Amman, Jordan

alexandrossfakianakis shared this article with you from Inoreader Clinical characteristics, outcomes, and seasonality of acute respiratory infection associated with single and co‐detected rhinovirus species among hospitalized children in Amman, Jordan via Journal of Medical Virology Abstract Background Rhinovirus (RV)-specific surveillance studies in the Middle East are limited. Therefore, we aimed to study the clinical characteristics, outcomes, and seasonality of RV-associated acute respiratory infection among hospitalized young children in Jordan. Methods We conducted a prospective viral surveillance study and enrolled children <2 years old admitted to a large public hospital in Amman, Jordan (2010–2013). Demographic and clinical data were collected by structured interviews and chart abstractions. Nasal and/or throat swabs were collected and tested for a panel of respiratory viruses, and RV genotyping and speciation was performed. Results At least one virus was detected in 2,641/3,168 children (83.4%). RV was the second most common virus detected (n=1,238; 46.9%) and was co-detected with another respiratory virus in 730 cases (59.0%). Children with RV co-detection were more likely than those with RV-only detection to have respiratory distress but had similar outcomes. RV-A accounted for about half of RV-positive cases (54.7%), while children with RV-C had a higher frequency of wheezing and reactive airway disease. RV was detected year-round and peaked during winter. Conclusions Though children with RV co-detection had worse clinical findings, neither co-detection nor species affected most clinical outcomes. This article is protected by copyright. All rights reserved. View on Web

Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.