Association of hidradenitis suppurativa with Crohn's disease

paythelady.612 shared this article with you from Inoreader Association of hidradenitis suppurativa with Crohn's disease Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 May 26;9(15):3506-3516. doi: 10.12998/wjcc.v9.i15.3506. ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder characterized by recurrent nodules, abscesses, and sinus tracts. Crohn's disease (CD) is characterized by inflammation of the entire digestive tract and belongs to the group of inflammatory bowel diseases, and there are many extraintestinal manifestations, among which hidradenitis suppurativa is one of the rare extraintestinal manifestations. There appears to be a strong association between CD and HS based on clinical and histological similarities (sinus tract development, granulomatous inflammation, and scarring), intersections in pathogenesis (genetic loci, immune dysregulation mechanisms, and microbiome changes), and commonality in treatment. In this review, we summarize recent studies on the association between HS and CD. PMID:34046451 | PMC:PMC8130070 | DOI:10.12998/wjcc.v9.i15.3506 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.