Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report

paythelady.612 shared this article with you from Inoreader Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Apr 6;9(10):2344-2351. doi: 10.12998/wjcc.v9.i10.2344. ABSTRACT BACKGROUND: Granulomatosis with polyangiitis is a necrotizing inflammation of small and medium-sized vessels accompanied by formation of granuloma, involvement of primary granulomatous upper and lower respiratory tracts, glomerulonephritis, and vasculitis of small vessels. CASE SUMMARY: Herein, we described a case of a 52-year-old man admitted with pulmonary nodules and high fever. Autoantibody workup revealed that the patient was positive for c-anti-neutrophil cytoplasmic antibodies and proteinase-3 anti-neutrophil cytoplasmic antibodies. Pulmonary biopsies revealed a local granulomatous structure. The patient received therapy with methylprednisolone and intravenous immunoglobulin, and his clinical symptoms improved. CONCLUSION: Intravenous immunoglobulin may act on granulomatosis with polyangiitis similar to immunosuppressants. PMID:33869612 | PMC:PMC8026843 | DOI:10.12998/wjcc.v9.i10.2344 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.