Message: https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00405-015-3701-y/MediaObjects/405_2015_3701_Fig1_HTML.jpg https://authorea.com/users/344181/articles/470848-a-comparison-between-mygind-and-kaiteki-positions-in-administration-of-drops-to-the-olfactory-cleft/master/file/figures/Figure%201%20july/Figure%201%20july.png?1606681897 A Comparison between Mygind and Kaiteki positions in administration of drops to the olfactory cleft Dafna G. Milk Grace C. Khong Osman H. Çam Fernando Alfaro‐Iraheta Claire Tierney Firas Kassem Samuel C. Leong First published: 16 December 2020 https://doi.org/10.1111/coa.13690 The study was performed at the Human Anatomy Resource Center, University of Liverpool, UK Read the full text PDFPDFTOOLS SHARE Abstract Objectives Topical nasal steroids are a common treatment intervention for olfactory dysfunction. Penetration of topical treatment to the olfactory cleft (OC), such as nasal drops, is greatly dependent on the position of the head when the treatment is administered. We aimed to examine the penetrance of nasal drops to the OC in two different head positions: the Mygind (lying head back) position and the Kaiteki position. Design and Setting The specimens were firstly positioned in Mygind, and thereafter in Kaiteki positions. Nasal drops mixed with blue food dye were administered into the nostrils in each of the head position. Endoscopic videos were recorded, and two blinded observers scored the extent of olfactory cleft penetration (OCP) using a 4‐point scale (0 = none, 3 = heavy). Participants Twelve fresh‐frozen cadaver specimens. Main outcome measures Penetration of the dye into the OC. Results The mean score of nasal drops penetrance to the OC in the Mygind position was 1.34 (standard deviation, SD = 0.92), as compared to 1.76 (SD = 0.65) in the Kaiteki position. The difference in the OCP score between the two groups was not statistically significant (P > .05). Conclusion Both Mygind and Kaiteki head positions are reasonable options for patients considering topical nasal drops for olfaction impairment. The preference of one position over the other should be determined by patient's preference and comfort. Open Research Volume46, Issue2 March 2021 Pages 406-411 Related Information Metrics Article has an altmetric score of 2 Details © 2021 John Wiley & Sons Ltd Keywords anosmia nasal drops olfaction olfactory cleft Publication History Issue Online: 23 February 2021 Version of Record online: 03 January 2021 Accepted manuscript online: 16 December 2020 Manuscript accepted: 29 November 2020 Manuscript revised: 07 November 2020 Manuscript received: 18 July 2020 Download PDF Back Additional links About Wiley Online Library Privacy Policy Terms of Use Cookies Accessibility Help & Support Contact Us Opportunities Subscription Agents Advertisers & Corporate Partners Connect with Wiley The Wiley Network Wiley Press Room Copyright © 1999-2021 John Wiley & Sons, Inc. All rights reservedWiley Home Page Rhinology Published: 04 July 2015 The administration of nasal drops in the "Kaiteki" position allows for delivery of the drug to the olfactory cleft: a pilot study in healthy subjects Eri Mori, Christos Merkonidis, Mandy Cuevas, Volker Gudziol, Yoshinori Matsuwaki & Thomas Hummel European Archives of Oto-Rhino-Laryngology volume 273, pages939–943(2016)Cite this article 544 Accesses 10 Citations 1 Altmetric Metricsdetails Abstract Systemic treatment with corticosteroids shows therapeutic effects, few patients benefit from intranasal topical drug application, probably due to limited access of the drug to the olfactory epithelium. The aim of the present study was to investigate how drops distribute within the nasal cavity when the "Kaiteki" position is performed. Thirteen healthy volunteers participated. Subjects were lying on the side with the head tilted and the chin turned upward. Blue liquid was used to visualize the intranasal distribution of the nasal drops. The investigation was carried out using photo documentation thorough nasal endoscopy; the intranasal distribution of the dye was judged by two independent observers in both a decongested state and a natural state where no decongestants had been used. With regard to the main criterion of this study, using the "Kaiteki" position, nasal drops reached the olfactory cleft in 96 % of the decongested cases and 75 % of the cases who had not been decong ested. However, this difference was not statistically different. Because the "Kaiteki" maneuver is not too difficult to perform, it is more likely that topical steroids can be helpful in cases of olfactory loss. This is a preview of subscription content, access via your institution. References 1. Landis BN, Konnerth CG, Hummel T (2004) A study on the frequency of olfactory dysfunction. Laryngoscope 114:1764–1769 CAS Article PubMed Google Scholar 2. Brämerson A, Johansson L, Ek L, Nordin S, Bende M (2004) Prevalence of olfactory dysfunction: the Skövde population-based study. Laryngoscope 114:733–737 Article PubMed Google Scholar 3. Murphy C, Schubert CR, Cruickshanks KJ, Klein BE, Klein R, Nondahl DM (2002) Prevalence of olfactory impairment in older adults. JAMA 288:2307–2312 Article PubMed Google Scholar 4. Damm M, Temmel A, Welge-Lüssen A, Eckel HE, Kreft MP, Klussmann JP, Gudziol H, Hüttenbrink KB, Hummel T (2004) Epidemiologie und Therapie von Riechstörungen in Deutschland. Österreich und der Schweiz. HNO 52:112–120 CAS Google Scholar 5. Heilmann S, Hüttenbrink KB, Hummel T (2004) Local and systemic administration of corticosteroids in the treatment of olfactory loss. Am J Rhinol 18:29–33 PubMed Google Scholar 6. Scheibe M, Bethge C, Witt M, Hummel T (2008) Intranasal administration of drugs. Arch Otorhinolaryngol Head Neck Surg 134:643–646 Article Google Scholar 7. Lam K, Tan BK, Lavin JM, Meen E, Conley DB (2013) Comparison of nasal sprays and irrigations in the delivery of topical agents to the olfactory mucosa. Laryngoscope 123:2950–2957 Article PubMed Google Scholar 8. Miyazaki J, Matsushita H, Yamada S, Inokuchi A (2004) New method for effective instillation of nasal drops in patients with olfactory dysfunction. Pract Oto-Rhino-Laryngol 97:697–705 Article Google Scholar 9. Kubba H, Spinou E, Robertson A (2000) The effect of head position on the distribution of drops within the nose. Am J Rhinol 14:83–86 CAS Article PubMed Google Scholar 10. Benninger MS, Hadley JA, Osguthorpe JD, Marple BF, Leopold DA, Derebery MJ, Hannley M (2004) Techniques of intranasal steroid use. Otolaryngol Head Neck Surg 130:5–24 Article PubMed Google Scholar 11. Shu CH, Lee PL, Shiao AS, Chen KT, Lan MY (2012) Topical corticosteroid applied with a squirt system being more effective than with nasal spray for steroid-dependent olfactory impairment. Laryngoscope 122:747–750 CAS Article PubMed Google Scholar 12. Blomqvist EH, Lundblad L, Bergstedt H, Stjarne P (2003) Placebo-controlled, randomized, double-blind study evaluating the efficacy of fluticasone propionate nasal spray for the treatment of patients with hyposmia/anosmia. Acta Otolaryngol 123:862–868 CAS Article PubMed Google Scholar 13. Klimek L, Hummel T, Moll B, Kobal G, Mann WJ (1998) Lateralized and bilateral olfactory function in patients with chronic sinusitis compared with healthy control subjects. Laryngoscope 108:111–114 CAS Article PubMed Google Scholar 14. Kayarkar R, Clifton NJ, Woolford TJ (2002) An evaluation of the best head position for instillation of steroid nose drops. Clin Otolaryngol Allied Sci 27:18–21 CAS Article PubMed Google Scholar 15. Karagama YG, Lancaster JL, Karkanevatos A, O'Sullivan G (2001) Delivery of nasal drops to the middle meatus: which is the best head position? Rhinology 39:226–229 CAS PubMed Google Scholar 16. Wolfensberger M, Hummel T (2002) Anti-inflammatory and surgical therapy of olfactory disorders related to sino-nasal disease. Chem Senses 27:617–622 Article PubMed Google Scholar 17. Pade J, Hummel T (2008) Olfactory function following nasal surgery. Laryngoscope 118:1260–1264 Article PubMed Google Scholar 18. Vandenhende-Szymanski C, Hochet B, Chevalier D, Mortuaire G (2015) Olfactory cleft opacity and CT score are predictive factors of smell recovery after surgery in nasal polyposis. Rhinology 53:29–34 CAS PubMed Google Scholar |
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,