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Τετάρτη 9 Δεκεμβρίου 2020

Out of Phase: How IPMK Inhibits TFEB.

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Out of Phase: How IPMK Inhibits TFEB.

Dev Cell. 2020 Dec 07;55(5):517-519

Authors: Ferrari L, Martens S

Abstract
The expression of autophagy and lysosomal genes is coordinated by the transcription factor EB (TFEB). In this issue of Developmental Cell, Chen et al. identify an evolutionary conserved mode of TFEB regulation, which entails the inhibition of TFEB phase separation in the nucleus by inositol polyphosphate multikinase.

PMID: 33290690 [PubMed - as supplied by publisher]
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,

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