The Mechanisms of Type 2 Diabetes-Related White Matter Intensities: A Review

alkiviadis.1961 shared this article with you from Inoreader The Mechanisms of Type 2 Diabetes-Related White Matter Intensities: A Review Via Frontiers in Public Health | New and Recent Articles The continually increasing number of patients with type 2 diabetes is a worldwide health problem, and the incidence of microvascular complications is closely related to type 2 diabetes. Structural brain abnormalities are considered an important pathway through which type 2 diabetes causes brain diseases. In fact, there is considerable evidence that type 2 diabetes is associated with an increased risk of structural brain abnormalities such as lacunar infarcts (LIs), white matter hyperintensities (WMHs), and b rain atrophy. WMHs are a common cerebral small-vessel disease in elderly adults, and it is characterized histologically by demyelination, loss of oligodendrocytes, and vacuolization as a result of small-vessel ischemia in the white matter. An increasing number of studies have found that diabetes is closely related to WMHs. However, the exact mechanism by which type 2 diabetes causes WMHs is not fully understood. This article reviews the mechanisms of type 2 diabetes-related WMHs to better understand the disease and provide help for better clinical treatment. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.