AtmosphereAtmosphere, Vol. 11, Pages 959: Clima...
Cannonball jellyfish digestion: an insight into the lipolytic enzymes of the digestive system: The digestive system and metabolism of the cannonball jellyfish Stomolophus sp. 2 are not well-known. The digestion study was critical to explain its ecology and bloom success. Different enzymes are involved in food digestion, which hydrolyze carbohydrates, proteins, and lipids. This study detected lipolytic activity in enzymatic extracts from gastric pouches of Stomolophus sp. 2 collected in the summer...
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Advances and complications of regenerative medicine in diabetes therapy: The rapid development of technologies in regenerative medicine indicates clearly that their common application is not a matter of if, but of when. However, the regeneration of beta-cells for diabetes patients remains a complex challenge due to the plurality of related problems. Indeed, the generation of beta-cells masses expressing marker genes is only a first step, with maintaining permanent insulin secretion, their protection...
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A new basal ornithopod dinosaur from the Lower Cretaceous of China: A new basal ornithopod dinosaur, based on two nearly complete articulated skeletons, is reported from the Lujiatun Beds (Yixian Fm, Lower Cretaceous) of western Liaoning Province (China). Some of the diagnostic features of Changmiania liaoningensis nov. gen., nov. sp. are tentatively interpreted as adaptations to a fossorial behavior, including: fused premaxillae; nasal laterally expanded, overhanging the maxilla; shortened neck...
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Transoral Robotic Surgery and De-escalation of Cancer Treatment: This article outlines the ways that transoral robotic surgery and transoral laser microsurgery relate to treatment de-escalation in the treatment of head and neck cancer. Treatment de-escalation has particular importance in context of human papillomavirus–related oropharynx squamous cell carcinoma, which responds well to therapy but leaves many survivors with decades of treatment-related sequelae. We compare these less invasive transoral...
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Evaluation of Lateral-Flow Assay for Rapid Detection of Influenza Virus: Background. Influenza virus mainly causes acute respiratory infections in humans. However, the diagnosis of influenza is not accurate based on clinical evidence, as the symptoms of flu are similar to other respiratory virus. The lateral-flow assay is a rapid method to detect influenza virus. But the effectiveness of the technique in detecting flu viruses is unclear. Hence, a meta-analysis would be performed to evaluate the accuracy...
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Assessment of the Influence Systemic Cryotherapy Exerts on Chosen Skin Scores of Patients with Atopic Dermatitis: Pilot Study: Background. One of the most important tasks in the treatment of atopic dermatitis (AD) is alleviation of racking skin dryness and persistent pruritus, because these factors exert a significant influence on worsening patients' quality of life. Cryotherapy being a new form of rehabilitation in AD may supplement and support a long-term process of AD treatment, because it has...
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The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis
The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis: Objective. This study is aimed at exploring the accuracy of contrast-enhanced ultrasound (CEUS) in grading renal artery stenosis. Methods. 122 renal arteries with suspected renal artery stenosis were selected. DSA, DUS, and CEUS were performed for all patients with suspected renal artery stenosis in the research. DSA was selected as the gold standard. The sensitivity, specificity, accuracy, positive...
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Finding the Source of a "Thyroid Hormone Leak": Clinical Thyroidology, Volume 32, Issue 9, Page 450-453, September 2020.
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Effect of Calculated-Dose Versus Fixed-Dose Radioiodine Treatment of Graves' Hyperthyroidism on Ocular Complications: Clinical Thyroidology, Volume 32, Issue 9, Page 426-429, September 2020.
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A Dose-Dependent Association of Radioactive Iodine Treatment for Hyperthyroidism with Solid Cancer Mortality: Clinical Thyroidology, Volume 32, Issue 9, Page 422-425, September 2020.
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Initial ATA Sonographic Risk and Subsequent Growth Helps Identify Missed Malignancies in Initially Benign Thyroid Nodules: Clinical Thyroidology, Volume 32, Issue 9, Page 436-439, September 2020.
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Early Thyroidectomy May Decrease Mortality in Amiodarone-Induced Thyrotoxicosis Associated with Systolic Dysfunction: Clinical Thyroidology, Volume 32, Issue 9, Page 418-421, September 2020.
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What Are the Associations Between COVID-19 Infection and Thyroid Dysfunction?: Clinical Thyroidology, Volume 32, Issue 9, Page 415-417, September 2020.
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Promising Responsiveness to PD-1 Blockade with Spartalizumab in Anaplastic Thyroid Carcinoma: Clinical Thyroidology, Volume 32, Issue 9, Page 447-449, September 2020.
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How Often Is Thyroid Hormone Supplementation Needed After Thyroid Lobectomy?: Clinical Thyroidology, Volume 32, Issue 9, Page 433-435, September 2020.
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Left temporal hemorrhage caused by cerebral venous reflux of a brachio-brachial hemodialysis fistula
Left temporal hemorrhage caused by cerebral venous reflux of a brachio-brachial hemodialysis fistula: AbstractCentral vein disease (CVD) is a well-known complication of central venous cannulations, indwelling dialysis catheters, and arteriovenous grafts. Brachiocephalic vein (BCV) stenosis or thrombotic occlusion can occur in dialysis patients, and the presence of an ipsilateral arteriovenous fistula can cause cerebral venous hypertension due to retrograde flow in the ipsilateral jugular vein. A...
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Histopathologic prognostic indices in tongue squamous cell carcinoma: AbstractPurposeConsistent prognosticators are needed to guide adjuvant treatment in tongue squamous cell carcinoma (SCC). We validate the prognostic significance of histopathologic parameters in surgically treated tongue SCC. MethodsArchival specimens of 88 consecutive patients who were treated surgically for tongue SCC from 2003 to 2016 were re-analyzed by one pathologist. Patient records were retrospectively...
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Auditory dysfunction in type 2 Stickler Syndrome: AbstractPurposeTo present the extent and site of lesion of auditory dysfunction in a large cohort of individuals with type 2 Stickler Syndrome. Type 2 Stickler Syndrome results from a mutation in the gene coding for α-1 type XI pro-collagen, which has been identified in the human vitreous, cartilage and the cochlea of the mouse. The condition is characterised by classic ocular abnormalities, auditory dysfunction, osteoarthropathy and oro-facial dysplasia....
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Association between the 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene and sudden sensorineural hearing loss in Caucasian population: a meta-analysis: AbstractPurposeTo clarify the association between the 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) and sudden sensorineural hearing loss (SSNHL). MethodsA systematic literature search of related studies up to August 30, 2019 in the PubMed and Embase databases was performed, and the results...
09:53
PET/MRI in prostate cancer: a systematic review and meta-analysis: AbstractAimIn recent years, the clinical availability of scanners for integrated positron emission tomography (PET) and magnetic resonance imaging (MRI) has enabled the practical potential of multimodal, combined metabolic-receptor, anatomical, and functional imaging to be explored. The present systematic review and meta-analysis summarize the diagnostic information provided by PET/MRI in patients with prostate cancer (PCa). ...
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vanco-800CW Image-guided in situ detection of bacterial biofilms in a human prosthetic knee infection model: a feasibility study for clinical diagnosis of prosthetic joint infections: AbstractPurposeDue to an increased human life expectancy, the need to replace arthritic or dysfunctional joints by prosthetics is higher than ever before. Prosthetic joints are unfortunately inherently susceptible to bacterial infection accompanied by biofilm formation. Accurate and rapid diagnosis is vital to increase...
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Evaluation of photobiomodulation therapy to accelerate bone formation in the mid palatal suture after rapid palatal expansion: a randomized clinical trial: AbstractTo evaluate the efficiency of photobiomodulation therapy (PBMT) in the midpalatal suture (MPS) and pain sensation in patients undergoing rapid palatal expansion (RPE). Thirty-four individuals with the diagnosis of skeletal maxillary hypoplasia were divided in two groups: laser (n = 18) and control (n = 16). Treatment plan consisted of...
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Bisphosphonate-related osteonecrosis induced change in alveolar bone architecture in rats with participation of Wnt signaling: AbstractObjectiveThis work aimed to study the role of inflammation in medication-related osteonecrosis of the jaw (MRONJ) in rats with focus on Wnt signaling. MethodsA total of 36 female Wistar rats (12 weeks ± 200 g) were divided into 2 groups (n = 6) in 3 experiments: saline (SAL) and zoledronic acid (ZOL). For MRONJ induction, rats received 0.1 mg/kg...
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Anatomical analysis of mandibular posterior teeth for endodontic microsurgery: a cone-beam computed tomographic evaluation: AbstractObjectiveThe purpose of this study was to analyze the anatomical structures relevant for endodontic microsurgery in the mandibular posterior teeth using a cone-beam computed tomography (CBCT). Material and methodsA total of 963 mandibular posterior teeth were analyzed in CBCT scans from 133 patients. The buccolingual and mesiodistal dimensions of...
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'Possible shunt malfunction' pathway for paediatric hydrocephalus—a study of clinical outcomes and cost implications: AbstractBackgroundShunt insertion for hydrocephalus is a common paediatric neurosurgery procedure. Shunt complications are frequent with an estimated 20–40% failure rate within the first year, and 4.5% per year subsequently. We have an open-door 'possible shunt malfunction' pathway for children treated with a shunt or endoscopic third ventriculostomy, providing direct ward access...
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Radiation-induced lymphopenia during chemoradiation therapy for non-small cell lung cancer is linked with age, lung V5, and XRCC1 rs25487 genotype in lymphocytes: Low absolute lymphocyte counts (ALCs) during therapy have been linked not only with the risk of opportunistic infections (e.g. radiation-induced pneumonia) [1,2] but also with worse survival in patients receiving radiation therapy [3–9]. Moreover, the emergence of immunotherapy has greatly improved outcomes in some patients with lung cancer...
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Analysis of Cardiac Substructure Dose in a Large, Multi-Centre Danish Breast Cancer Cohort (the DBCG HYPO trial): Trends and Predictive Modelling: Background and purposeRadiotherapy for breast cancer can increase the risks of heart disease. Patient-specific risk assessment may be improved with the inclusion of doses to cardiac substructures. The purpose of this work was to use automatic segmentation to evaluate substructure doses and develop predictive models for these based on the dose to the whole...
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Multimodal CEA-targeted image-guided colorectal cancer surgery using 111In-labeled SGM-101: Purpose:Intraoperative image guidance may aid in clinical decision making during surgical treatment of colorectal cancer. We developed the dual-labeled CEA-targeting tracer [111In]In-DTPA-SGM-101 for pre- and intraoperative imaging of colorectal cancer. Subsequently we investigated the tracer in preclinical biodistribution and multimodal image-guided surgery studies, and assessed the clinical feasibility on...
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CSPG4-specific CAR.CIK lymphocytes as a novel therapy for the treatment of multiple soft tissue sarcoma histotypes: Purpose: No effective therapy is available for unresectable soft tissue sarcomas (STS). This unmet clinical need has prompted us to test whether chondroitin sulfate proteoglycan 4 (CSPG4)-specific CAR-redirected cytokine-induced killer lymphocytes (CAR.CIK) are effective in eliminating tumor cells derived from multiple STS histotypes in vitro and in immunodeficient mice. Experimental...
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AsiDNA is a radiosensitizer with no added toxicity in medulloblastoma pediatric models: Purpose: Medulloblastoma (MB) is an important cause of mortality and morbidity in pediatric oncology. Here we investigated whether the DNA repair inhibitor AsiDNA could help address a significant unmet clinical need in MB care, by improving radiotherapy efficacy without increasing radiation-associated toxicity. Experimental Design: To evaluate the brain permeability to AsiDNA upon systemic delivery, we injected...
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Safety Profile and Adverse Events of Special Interest for Fruquintinib in Chinese Patients with Previously Treated Metastatic Colorectal Cancer: Analysis of the Phase 3 FRESCO Trial: AbstractIntroductionIn FRESCO (Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients) trial, fruquintinib demonstrated a statistically significant and clinically meaningful overall survival benefit in Chinese patients with metastatic colorectal cancer (mCRC). However, its safety profile, including adverse...
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The oldest Neanderthal DNA of Central-Eastern Europe: A new study reports the oldest mitochondrial genome of a Neanderthal from Central-Eastern Europe. The mitochondrial genome of the tooth, discovered at the site of Stajnia Cave in Poland, is closer to a Neanderthal specimen from the Caucasus than to the contemporaneous Neanderthals of Western Europe. Stone tools found at the site are also analogous to the southern regions suggesting that Neanderthals living in the steppe/taiga environment had a...
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The Utility of Resolving Asthma Molecular Signatures Using Tissue-Specific Transcriptome Data: An integrative analysis focused on multi-tissue transcriptomics has not been done for asthma. Tissue-specific DEGs remain undetected in many multi-tissue analyses, which influences identification of disease-relevant pathways and potential drug candidates. Transcriptome data from 609 cases and 196 controls, generated using airway epithelium, bronchial, nasal, airway macrophages, distal lung fibroblasts,...
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Nonsurgical Thermal Ablation of Thyroid Nodules: Not if, but Why, When, and How?: Thyroid, Ahead of Print.
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Urinary Iodine and Genetic Predisposition to Hashimoto's Thyroiditis in a Chinese Han Population: A Case–Control Study: Thyroid, Ahead of Print. AbstractBackground: We aimed to examine the association of urinary iodine concentration with Hashimoto's thyroiditis (HT) risk, and particularly, to investigate whether the HT-related genetic variations might modify the effects of urinary iodine on HT in the Chinese Han population.Methods: We conducted a case–control study with 1723 Chinese (731 cases, 992...
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Updates on Combination Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: AbstractPurpose of ReviewMethicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with a large clinical burden and high rates of treatment failure with first-line treatment options. Literature for combination antimicrobial therapies for initial treatment or salvage therapy in the setting of persistent bacteremia is developing. Recent FindingsVarious combination strategies...
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Development of a non-invasive exhaled breath test for the diagnosis of head and neck cancer: British Journal of Cancer, Published online: 09 September 2020; doi:10.1038/s41416-020-01051-9Development of a non-invasive exhaled breath test for the diagnosis of head and neck cancer Nuwan Dharmawardana, Thomas Goddard, Charmaine Woods, David I. Watson, Eng H. Ooi & Roger Yazbeck British Journal of Cancer (2020)Cite this articleMetricsdetailsAbstractBackgroundImproving the ability to identify early-stage...
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Extracranial Meningioma in the Scalp with Concurrent Steatocystoma: This report documents a rare case of an extracranial meningioma on the posterior scalp without apparent dural connection. Additionally, a sebaceous steatocystoma of the anterior scalp presented alongside the meningioma. A steatocystoma localized to the scalp is also remarkably rare. To our knowledge, this is the first report documenting both an extracranial meningioma and a steatocystoma presenting concurrently on the scalp. A male...
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[Activity of chronic spontaneous urticaria in euthyroid vs hypothyroid patients].: Related Articles[Activity of chronic spontaneous urticaria in euthyroid vs hypothyroid patients].Rev Alerg Mex. 2020 Apr-Jun;67(2):112-118Authors: Herrera-Sánchez DA, Álvarez-Chávez FE, O Farrill-Romanillos PMAbstract BACKGROUND: Chronic urticaria (CU) affects 5 % of the general population and it is associated with thyroid disease in up to 54 % of patients. There is scarce information on the activity of urticaria...
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[Giant coronary aneurysms in infant with Kawasaki disease shock syndrome].: Related Articles[Giant coronary aneurysms in infant with Kawasaki disease shock syndrome].Rev Alerg Mex. 2020 Apr-Jun;67(2):174-182Authors: García-Domínguez M, Riviera-Navarro D, Quibrera J, Pérez-Gaxiola GAbstract BACKGROUND: Kawasaki disease shock syndrome is a rare presentation of Kawasaki disease, in which cardiovascular manifestations associated with elevated inflammation biomarkers that develop hypotension...
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[Hemophagocytic syndrome associated with Hodgkin lymphoma and Epstein-Barr virus infection. A case report].: Related Articles[Hemophagocytic syndrome associated with Hodgkin lymphoma and Epstein-Barr virus infection. A case report].Rev Alerg Mex. 2020 Apr-Jun;67(2):183-188Authors: Noyola-García M, González-Ríos RD, Olascoaga-Lugo A, Rodríguez-Florido MA, Rubio-Anguiano BLAbstract BACKGROUND: Hodgkin lymphoma is a malignant neoplasm of B lymphoid cells whose histologic characteristic is the...
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[Drug provocation tests to identify analgesic alternatives for an infant with Stevens-Johnson syndrome caused by ibuprofen-acetaminophen].: Related Articles[Drug provocation tests to identify analgesic alternatives for an infant with Stevens-Johnson syndrome caused by ibuprofen-acetaminophen].Rev Alerg Mex. 2020 Apr-Jun;67(2):189-195Authors: Abreu S, Castelblanco-Arango IY, Gómez-Pineda PA, Cardona RAbstract BACKGROUND: The Stevens-Johnson syndrome is a serious skin reaction to drugs, and...
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Correlation between TSH levels and quality of life among subjects with well-controlled primary hypothyroidism: AbstractPurposeIt has been suggested that increasing levothyroxine dose to lower TSH levels within the normal laboratory range might be a therapeutic option for patients with apparently well-controlled primary hypothyroidism who are dissatisfied with their treatment and complain of physical or psychological symptoms. This study assessed whether there is a relationship between TSH levels...
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Alcohol and HomeostasisEffect of hypertriglyceridemia in dyslipidemia-induced impaired glucose tolerance and sex differences in dietary features associated with hypertriglyceridemia among the Japanese population: The Gifu Diabetes Study.Related Articles Effect of hypertriglyceridemia in dyslipidemia-induced impaired glucose tolerance and sex differences in dietary features associated with hypertriglyceridemia among the Japanese population: The Gifu Diabetes Study. J Diabetes Investig. 2020 Sep...
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NutrientsNutrients, Vol. 12, Pages 2735: Adipose Tissue Development and Expansion from the Womb to Adolescence: An OverviewNutrients, Vol. 12, Pages 2735: Adipose Tissue Development and Expansion from the Womb to Adolescence: An Overview Nutrients doi: 10.3390/nu12092735 Authors: Camila E. Orsso Eloisa Colin-Ramirez Catherine J. Field Karen L. Madsen Carla M. Prado Andrea M. Haqq Prevalence rates of pediatric obesity continue to rise worldwide. Adipose tissue (AT) development and expansion initiate...
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LifeLife, Vol. 10, Pages 183: Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in AstrocytesLife, Vol. 10, Pages 183: Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes Life doi: 10.3390/life10090183 Authors: Bruno Di Marco Vieira Rowan A. W. Radford Junna Hayashi Emma D. Eaton Ben Greenaway Mark Jambas Eugen B. Petcu Roger S. Chung Dean L. Pountney Multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are α-synucleinopathies...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 6545: Suboptimal Serum 25-Hydroxy-Vitamin D Is Associated with a History of Recent Disease Exacerbation in Pediatric Patients with Bronchial Asthma or Asthma-Suggestive Recurrent WheezingIJERPH, Vol. 17, Pages 6545: Suboptimal Serum 25-Hydroxy-Vitamin D Is Associated with a History of Recent Disease Exacerbation in Pediatric Patients with Bronchial Asthma or Asthma-Suggestive Recurrent Wheezing International...
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CellsCells, Vol. 9, Pages 2046: Dendritic Cells and SARS-CoV-2 Infection: Still an Unclarified ConnectionCells, Vol. 9, Pages 2046: Dendritic Cells and SARS-CoV-2 Infection: Still an Unclarified Connection Cells doi: 10.3390/cells9092046 Authors: Pasquale Campana Valentina Parisi Dario Leosco Debora Bencivenga Fulvio Della Ragione Adriana Borriello The ongoing pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has so far infected about 2.42 × 107 (as at 27 August 2020)...
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AntibioticsAntibiotics, Vol. 9, Pages 586: A New Water-Soluble Bactericidal Agent for the Treatment of Infections Caused by Gram-Positive and Gram-Negative Bacterial StrainsAntibiotics, Vol. 9, Pages 586: A New Water-Soluble Bactericidal Agent for the Treatment of Infections Caused by Gram-Positive and Gram-Negative Bacterial Strains Antibiotics doi: 10.3390/antibiotics9090586 Authors: Alessandro Presentato Elena Piacenza Antonino Scurria Lorenzo Albanese Federica Zabini Francesco Meneguzzo Domenico...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,