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Prediction Model Combining Clinical and MR Data for Diagnosis of Lymph Node Metastasis in Patients With Rectal Cancer.: Related ArticlesPrediction Model Combining Clinical and MR Data for Diagnosis of Lymph Node Metastasis in Patients With Rectal Cancer.J Magn Reson Imaging. 2020 Sep 26;:Authors: Xu H, Zhao W, Guo W, Cao S, Gao C, Song T, Yang L, Liu Y, Han Y, Zhang L, Wang KAbstract BACKGROUND: Determining the status of lymph node (LN) metastasis in rectal cancer patients preoperatively...
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Factors of Adjacent Segment Disease Onset After Microsurgical decompression for Lumbar Spinal Canal Stenosis.: Related ArticlesFactors of Adjacent Segment Disease Onset After Microsurgical decompression for Lumbar Spinal Canal Stenosis.World Neurosurg. 2020 Sep 23;:Authors: Yokoyama K, Yamada M, Tanaka H, Ito Y, Sugie A, Wanibuchi M, Kawanishi MAbstract OBJECTIVE: Few studies have examined the underlying cause of Adjacent segment disease (ASD) after decompression surgery for LSS. The goal...
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Association between stroke lesions and videofluoroscopic findings in acute stroke patients.: Related ArticlesAssociation between stroke lesions and videofluoroscopic findings in acute stroke patients.J Neurol. 2020 Sep 26;:Authors: Nakamori M, Hosomi N, Imamura E, Matsushima H, Maetani Y, Yoshida M, Yoshikawa M, Takeda C, Nagasaki T, Masuda S, Kayashita J, Tsuga K, Tanimoto K, Wakabayashi S, Maruyama HAbstract BACKGROUND AND PURPOSE: We aimed to assess stroke lesions, which play a key role...
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Clear cell hidradenoma of the hand: A case report in an 83-year old patient.: Related ArticlesClear cell hidradenoma of the hand: A case report in an 83-year old patient.Int J Surg Case Rep. 2020 Sep 19;75:307-310Authors: Efremov K, Caterini A, Petrungaro L, De Maio F, Di Prete M, Ferlosio A, Tresoldi I, Farsetti PAbstract INTRODUCTION: Clear cell hidradenoma (CCH) is a superficial adnexal tumor of the sweat glands. It generally appears on the trunk or scalp and is uncommon on the upper...
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Radical surgery for primary thyroid lymphoma in a Filipino female: Report of a case and review of literature.: Related ArticlesRadical surgery for primary thyroid lymphoma in a Filipino female: Report of a case and review of literature.Int J Surg Case Rep. 2020 Sep 19;75:302-306Authors: Perez AR, Perez MEC, Arcilla CEAbstract INTRODUCTION: Primary thyroid lymphomas are rare. They constitute only 2% of all thyroid malignancies. It is important to distinguish it from other tumors of the thyroid...
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Synchronous sigmoid and transverse volvulus: A case report and qualitative systematic review.: Related ArticlesSynchronous sigmoid and transverse volvulus: A case report and qualitative systematic review.Int J Surg Case Rep. 2020 Sep 10;75:297-301Authors: Ndong A, Diao ML, Tendeng JN, Diallo AC, Ma Nyemb PM, Konaté IAbstract INTRODUCTION: Colonic volvulus is defined as a torsion of a part of the colon causing large bowel obstruction by strangulation which may lead to ischemia and then necrosis....
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Unusual techniques in the management of enteroatmospheric fistula. Report of a case.: Related ArticlesUnusual techniques in the management of enteroatmospheric fistula. Report of a case.Int J Surg Case Rep. 2020 Sep 10;75:292-296Authors: Saleem A, Farsi AAbstract INTRODUCTION: Enteroatmospheric fistula (EAF) is one of the most challenging postoperative complications following gastrointestinal surgery. Different techniques have been reported for managing the open abdomen and controlling the...
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Langerhans cell histiocytosis in the adult clavicle: A case report.: Related ArticlesLangerhans cell histiocytosis in the adult clavicle: A case report.Int J Surg Case Rep. 2020 Sep 11;75:286-291Authors: Song MG, Nam DC, Lee JS, Kim DHAbstract INTRODUCTION: Langerhans` Cell Histiocytosis (LCH) is a rare disease involving proliferation of Langerhans-type cells, which shares immunophenotypic and ultrastructural similarities. In this article, we report a case of Langerhans cell histiocytosis...
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Perioperative FOLFOX in management of peritoneal metastases of colorectal cancer. Case report of 2 patients.: Related ArticlesPerioperative FOLFOX in management of peritoneal metastases of colorectal cancer. Case report of 2 patients.Int J Surg Case Rep. 2020 Sep 10;75:279-285Authors: Sugarbaker PH, Stuart OAAbstract INTRODUCTION: Colorectal cancer can disseminate malignant cells to the peritoneal surfaces which over time progress to peritoneal metastases. Management of this type of metastatic...
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An unusual clinical presentation of colonic lipomatosis: A case report.: Related ArticlesAn unusual clinical presentation of colonic lipomatosis: A case report.Int J Surg Case Rep. 2020 Aug 29;75:273-275Authors: Dajti G, Vagliasindi A, Bosi S, Guerra E, Zanzi F, Raulli GDAbstract INTRODUCTION: Colonic lipomatosis is defined as a poorly circumscribed, non-capsulated fat accumulation in the submucosal layer of the colonic wall. Clinical presentation varies from asymptomatic to acute surgical...
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Hepatic artery aneurysm: A case report of a novel approach to an age old problem.: Related ArticlesHepatic artery aneurysm: A case report of a novel approach to an age old problem.Int J Surg Case Rep. 2020 Sep 17;75:269-272Authors: Barry IP, Stanley BAbstract INTRODUCTION: Visceral artery aneurysms are a relatively uncommon but potentially devastating pathology. The most common site is the splenic artery followed by the hepatic (Stanley et al., 1986) [1]. In the event of rupture, mortality...
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A case report of anorectal malignant melanoma in the transitional zone.: Related ArticlesA case report of anorectal malignant melanoma in the transitional zone.Int J Surg Case Rep. 2020 Sep 17;75:264-268Authors: Nguyen MT, Nguyen VM, Tran VH, Pham AVAbstract INTRODUCTION: Anorectal malignant melanoma is an uncommon and highly malignant disease with a greater incidence in females. Many patients were misdiagnosed as hemorrhoids, benign polyps, and rectal cancer. They were often diagnosed in...
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Covering a large abdominal wall defect using bilateral anterolateral myocutaneous thigh flap: A case report.: Related ArticlesCovering a large abdominal wall defect using bilateral anterolateral myocutaneous thigh flap: A case report.Int J Surg Case Rep. 2020 Sep 17;75:261-263Authors: Salih AM, Kakamad FH, Najar KA, Mohammed KK, Mohammed DA, Mohammed SHAbstract INTRODUCTION: Closure of the abdominal wall defect by myocuteous thigh flap is an option. The aim of this paper is to report a case...
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Synchronous sigmoid cancer and abdominal aortic aneurysm treated by laparoscopic colectomy followed by endovascular aneurysm repair.: Related ArticlesSynchronous sigmoid cancer and abdominal aortic aneurysm treated by laparoscopic colectomy followed by endovascular aneurysm repair.Int J Surg Case Rep. 2020 Aug 29;75:238-241Authors: Hamid M, Benammi S, Bounssir A, Bakali Y, Lekehal B, Hrora AAbstract INTRODUCTION: The occurrence of synchronous abdominal aorta aneurysms and colorectal cancer...
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Interpositional collagenated cancellous bone blocks for nasal dorsum augmentation: A new technique for nasomaxillary hypoplasia treatment.: Related ArticlesInterpositional collagenated cancellous bone blocks for nasal dorsum augmentation: A new technique for nasomaxillary hypoplasia treatment.J Plast Reconstr Aesthet Surg. 2020 Sep 20;:Authors: Hernández-Alfaro F, González-Soto J, Giralt-Hernando M, Masià-Gridilla J, Raffaini M, Valls-Ontañón AAbstract Nasomaxillary hypoplasia is a rare...
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St Andrew's COVID-19 surgery safety (StACS) study: Elective plastic surgery, trauma & burns.: Related ArticlesSt Andrew's COVID-19 surgery safety (StACS) study: Elective plastic surgery, trauma & burns.J Plast Reconstr Aesthet Surg. 2020 Aug 21;:Authors: Miranda BH, Hughes WRM, Pinto-Lopes R, Mathur BS, Ramakrishnan VV, Sood MK, St Andrew's CollaborativeAbstract INTRODUCTION: This study evaluates COVID-19 related patient risk, when undergoing management within one of the largest...
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Gut amyloid‐β induces cognitive deficits and Alzheimer's disease‐related histopathology in a mouse model: PMC2813509J Alzheimers Dis. Author manuscript; available in PMC 2010 Jan 29.Published in final edited form as:J Alzheimers Dis. 2010 Jan; 19(1): 311.doi: 10.3233/JAD-2010-1221PMCID: PMC2813509NIHMSID: NIHMS171690PMID: 20061647Alzheimer's Disease and the β-Amyloid PeptideM. Paul Murphy and Harry LeVine, IIIAuthor information Copyright and License information DisclaimerDepartment of Molecular and...
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A horse of a different colour: distinct mechanisms of HFpEF and HFrEF: PMC6952981Cells. 2019 Dec; 8(12): 1651.Published online 2019 Dec 16. doi: 10.3390/cells8121651PMCID: PMC6952981PMID: 31888288Heart Failure with Reduced Ejection Fraction (HFrEF) and Preserved Ejection Fraction (HFpEF): The Diagnostic Value of Circulating MicroRNAsYei-Tsung Chen,1,2,3,* Lee Lee Wong,2,3 Oi Wah Liew,2,3 and Arthur Mark Richards2,3,4Author information Article notes Copyright and License information Disclaimer1Department...
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YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation: AbstractMost cancer cells are exposed to altered extracellular environments, such as an increase in extracellular matrix (ECM) stiffness and soluble signals consisting of growth factors and cytokines. It is therefore conceivable that changes in tumor extracellular environments affect tumor cell behavior. The Hippo pathway reportedly responds to the extracellular environment and regulates the nuclear localization...
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Effect of highly effective modulator therapy on quality of life in adults with cystic fibrosis: BackgroundElexacaftor/tezacaftor/ivacaftor is a highly effective modulator that improves function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, resulting in improved pulmonary function in patients with cystic fibrosis (CF). We hypothesize that improvements in lung function are associated with improvements in health‐related quality of life and sinonasal health. The aim of this...
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Transcervical endoscopic retropharyngeal lymph node (RPLN) dissection in nasopharyngeal carcinoma with RPLN recurrence: AbstractBackgroundSurgical access for retropharyngeal lymph node (RPLN) dissection is difficult. We aimed to examine the efficacy of transcervical endoscopic RPLN dissection (TSE‐RPLND) for recurrent RPLN in nasopharyngeal carcinoma (NPC).MethodsFrom April 2013 to February 2019, a total of 31 patients with NPC diagnosed with RPLN recurrence underwent TSE‐RPLND. The clinical characteristics,...
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Association between swallowing function and muscle strength in elderly individuals with dysphagia.: Related ArticlesAssociation between swallowing function and muscle strength in elderly individuals with dysphagia.Auris Nasus Larynx. 2020 Sep 23;:Authors: Sugaya N, Goto F, Okami K, Nishiyama KAbstract OBJECTIVE: This study aimed to investigate the association among swallowing function, hand grip strength, and peak expiratory flow in elderly patients with dysphagia. METHODS: A total...
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Polyamines in the Virulence of Bacterial Pathogens of Respiratory Tract.: Related ArticlesPolyamines in the Virulence of Bacterial Pathogens of Respiratory Tract.Mol Oral Microbiol. 2020 Sep 26;:Authors: Banerji R, Kanojiya P, Patil A, Saroj SDAbstract Polyamines are positively charged hydrocarbons that are essential for the growth and cellular maintenance in prokaryotes and eukaryotes. Polyamines have been demonstrated to play a role in bacterial pathogenicity and biofilm formation. However,...
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Why COVID-19 is less frequent and severe in children: a narrative review.: Related ArticlesWhy COVID-19 is less frequent and severe in children: a narrative review.World J Pediatr. 2020 Sep 25;:Authors: Sinaei R, Pezeshki S, Parvaresh S, Sinaei RAbstract BACKGROUND: Despite the streaks of severity, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection is, in general, less frequent and severe in children than in adults. We searched for causal evidence of this mystery. ...
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Is dental caries associated with lower respiratory tract infections?: Related ArticlesIs dental caries associated with lower respiratory tract infections?Evid Based Dent. 2020 Sep;21(3):106-107Authors: Chestnutt IGAbstract Design This study comprised an analysis of data from a cohort, born in the Finnish city of Espoo between January 1 1984 and March 31 1990.Objectives The objective of the study was to investigate the effect of dental caries on the risk of lower respiratory tract infections...
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A transient increase in MHC-IIlow monocytes after experimental infection with Avibacterium paragallinarum (serovar B-1) in SPF chickens.: Related ArticlesA transient increase in MHC-IIlow monocytes after experimental infection with Avibacterium paragallinarum (serovar B-1) in SPF chickens.Vet Res. 2020 Sep 25;51(1):123Authors: Alvarez KLF, Poma-Acevedo A, Fernández-Díaz MAbstract Infectious coryza (IC), an upper respiratory tract disease affecting chickens, is caused by Avibacterium paragallinarum....
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Bladder preservation therapy for muscle invasive bladder cancer: the past, present and future: AbstractRadical cystectomy is the gold standard treatment for muscle invasive bladder cancer, but some patients have medically inoperable disease or refuse cystectomy to preserve their bladder function. Bladder preservation therapy with transurethral resection of the bladder tumor and concurrent chemoradiotherapy, known as trimodal treatment, is regarded to be a curative-intent alternative to radical cystectomy...
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Ventriculoatrial and ventriculopleural shunts as second-line surgical treatment have equivalent revision, infection, and survival rates in paediatric hydrocephalus: AbstractPurposeVentriculoatrial (VA) and ventriculopleural (VPL) shunts are used as alternatives when CSF diversion to the peritoneal compartment with a ventriculoperitoneal (VP) shunt is not possible. The objective of this study is to compare directly the shunt survival and complications for both procedures in this setting in children....
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Brain Structural Changes in Focal Dystonia-What About Task Specificity? A Multimodal MRI Study.: Related ArticlesBrain Structural Changes in Focal Dystonia-What About Task Specificity? A Multimodal MRI Study.Mov Disord. 2020 Sep 26;:Authors: Tomić A, Agosta F, Sarasso E, Svetel M, Kresojević N, Fontana A, Canu E, Petrović I, Kostić VS, Filippi MAbstract BACKGROUND: The neural basis of task specificity in dystonia is still poorly understood. This study investigated gray and white matter (WM)...
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Performance of cochlear implant recipients fitted with triphasic pulse patterns.: Related ArticlesPerformance of cochlear implant recipients fitted with triphasic pulse patterns.Eur Arch Otorhinolaryngol. 2020 Sep 26;:Authors: Alhabib SF, Abdelsamad Y, Yousef M, Alzhrani FAbstract PURPOSE: To assess the effect of triphasic pulse pattern stimulation strategy on the audiological performance of cochlear implant recipients with unintended facial nerve stimulation (FNS), and to compare the audiological...
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The ability of the eating assessment tool-10 to detect penetration and aspiration in Parkinson's disease.: Related ArticlesThe ability of the eating assessment tool-10 to detect penetration and aspiration in Parkinson's disease.Eur Arch Otorhinolaryngol. 2020 Sep 26;:Authors: Schlickewei O, Nienstedt JC, Frank U, Fründt O, Pötter-Nerger M, Gerloff C, Buhmann C, Müller F, Lezius S, Koseki JC, Pflug CAbstract PURPOSE: Dysphagia is common in patients with Parkinson's disease (PD) and often...
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[Predictable toxicities with futures immunotherapies or combinations].: Related Articles[Predictable toxicities with futures immunotherapies or combinations].Bull Cancer. 2020 Sep 22;:Authors: Mogenet A, Tomasini P, Greillier L, Barlesi FAbstract Immunotherapy by immune check-points inhibitors (ICIs) recently improved many solid tumors survival data. ICIs target and inhibit down-regulation signals between T cells and tumor cells involved in carcinogenesis, in order to enhance anti-tumor...
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[First results of a breast cancer risk assessment and management consultation].: Related Articles[First results of a breast cancer risk assessment and management consultation].Bull Cancer. 2020 Sep 22;:Authors: Uzan C, Ndiaye-Guèye D, Nikpayam M, Oueld Es Cheikh E, Lebègue G, Canlorbe G, Azais H, Gonthier C, Belghiti J, Benusiglio PR, Séroussi B, Gligorov J, Uzan SAbstract INTRODUCTION: In France, participation in the organized breast cancer screening program remains insufficient. A personalized...
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[Dosimetric factors related to postoperative pulmonary complications in locally advanced esophageal cancers treated with preoperative chemoradiotherapy: Literature review].: Related Articles[Dosimetric factors related to postoperative pulmonary complications in locally advanced esophageal cancers treated with preoperative chemoradiotherapy: Literature review].Bull Cancer. 2020 Sep 22;:Authors: Dworczak M, Le Deley MC, Adenis A, Piessen G, Lartigau É, Mirabel X, Lacornerie T, Pasquier DAbstract ...
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[New European approvals: Alpelisib for HRpos/HER2neg metastatic breast cancer with PIK3CA mutation].: Related Articles[New European approvals: Alpelisib for HRpos/HER2neg metastatic breast cancer with PIK3CA mutation].Bull Cancer. 2020 Sep 22;:Authors: Corbaux P, Sabatier RPMID: 32977934 [PubMed - as supplied by publisher]
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Lumbar drains: Practical understanding and application for the otolaryngologist.: Related ArticlesLumbar drains: Practical understanding and application for the otolaryngologist.Am J Otolaryngol. 2020 Sep 19;41(6):102740Authors: Livingston AJ, Laing B, Zwagerman NT, Harris MSAbstract INTRODUCTION: Lumbar drains are frequently used in patients with otolaryngologic concerns. These can be used therapeutically or prophylactically with the primary purpose being to modulate CSF pressure. Within...
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The Current Landscape of Staging and Treatment of Colorectal Cancer in a Region of Ukraine: a Mixed Methods Study.: Related ArticlesThe Current Landscape of Staging and Treatment of Colorectal Cancer in a Region of Ukraine: a Mixed Methods Study.World J Surg. 2020 Sep 25;:Authors: Lu PW, Shabat G, Semeniv S, Fedorkiv M, Fields AC, Lyu HG, Beznosenko A, Davids JS, Melnitchouk NAbstract BACKGROUND: In Ukraine, the 1-year mortality for colorectal cancer is much higher than that seen in high-income...
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Outcome Predictors in Civilian and Iatrogenic Arterial Trauma.: Related ArticlesOutcome Predictors in Civilian and Iatrogenic Arterial Trauma.World J Surg. 2020 Sep 25;:Authors: Kakkos SK, Tyllianakis M, Panagopoulos A, Kokkalis Z, Lianou I, Koletsis E, Tsolakis I, Papadoulas S, Gliatis J, Maroulis I, Kitrou PAbstract BACKGROUND: Our aim was to identify predictors of mortality and limb loss in iatrogenic and civilian arterial trauma. METHODS: Cases were identified by searching prospectively...
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Prevalence of photoparoxysmal response in patients with epilepsy: Effect of the underlying syndrome and treatment status.: Related ArticlesPrevalence of photoparoxysmal response in patients with epilepsy: Effect of the underlying syndrome and treatment status.Seizure. 2020 Sep 18;82:39-43Authors: Rathore C, Prakash S, Makwana PAbstract OBJECTIVE: To prospectively study the prevalence of photoparoxysmal response (PPR) and its determinants in epilepsy patients. METHODS: Consecutive...
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Risk-benefit assessment of treatment of epileptic women of childbearing age with valproic acid.: Related ArticlesRisk-benefit assessment of treatment of epileptic women of childbearing age with valproic acid.Seizure. 2020 Sep 16;82:27-30Authors: Quílez A, Baraldés-Rovira M, Gallego Y, Sanahuja J, Mauri-Capdevila G, Purroy FAbstract AIM: Valproic acid (VPA) is a widely used anti-epileptic drug (AED) of demonstrated efficacy. However, its teratogenic effects have resulted in many regulatory...
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The efficacy of assisted reproductive treatment in women with epilepsy.: Related ArticlesThe efficacy of assisted reproductive treatment in women with epilepsy.Reprod Biomed Online. 2020 Aug 01;:Authors: Larsen MD, Jølving LR, Fedder J, Nørgård BMAbstract RESEARCH QUESTION: The question of interest for this study was to examine the chance of a live birth following assisted reproductive technology (ART) treatment in women with epilepsy compared with women without epilepsy. In sub-analyses,...
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Description of a giant hypothalamic hamartoma associated with an immature ruptured giant sacrococcygeal teratoma: a case report.: Related ArticlesDescription of a giant hypothalamic hamartoma associated with an immature ruptured giant sacrococcygeal teratoma: a case report.Childs Nerv Syst. 2020 Sep 25;:Authors: Serratrice N, Faure A, de Paula AM, Girard N, André N, Scavarda DAbstract Giant hypothalamic hamartomas (GHH) are rare neonatal intracerebral congenital malformations responsible...
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Multiscale in-vitro analysis of photo-activated riboflavin incorporated in an experimental universal adhesive.: Related ArticlesMultiscale in-vitro analysis of photo-activated riboflavin incorporated in an experimental universal adhesive.J Mech Behav Biomed Mater. 2020 Sep 15;112:104082Authors: Fu C, Deng S, Koneski I, Awad MM, Akram Z, Matinlinna J, Pichika MR, Daood U, Fawzy ASAbstract OBJECTIVE: To investigate the effect of blue light photoactivated riboflavin modified universal adhesives...
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Testing the theory of Differential Susceptibility to nightmares: The interaction of Sensory Processing Sensitivity with the relationship of low mental wellbeing to nightmare frequency and nightmare distress: SummaryPropensity to have nightmares has been theorised in terms of diathesis–stress models, with this propensity being seen as negative or even pathological. In contrast, a recent model proposes that nightmare propensity is due to Differential Susceptibility to stimuli, where high susceptibility...
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Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma.: Related ArticlesIdentification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma.Invest New Drugs. 2020 Sep 25;:Authors: Özenver N, Abdelfatah S, Klinger A, Fleischer E, Efferth TAbstract Multiple myeloma (MM) is a devastating disease with low...
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Overexpressed sFRP3 exerts an inhibitory effect on hepatocellular carcinoma via inactivation of the Wnt/β-catenin signaling pathway.: Related ArticlesOverexpressed sFRP3 exerts an inhibitory effect on hepatocellular carcinoma via inactivation of the Wnt/β-catenin signaling pathway.Cancer Gene Ther. 2020 Sep 26;:Authors: Fang L, Gao C, Bai RX, Wang HF, Du SYAbstract Hepatocellular carcinoma (HCC) is recognized as the most common malignancy of the liver in adults. Many human cancers have...
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FZR1 as a novel biomarker for breast cancer neoadjuvant chemotherapy prediction.: Related ArticlesFZR1 as a novel biomarker for breast cancer neoadjuvant chemotherapy prediction.Cell Death Dis. 2020 Sep 25;11(9):804Authors: Liu S, Wang H, Li J, Zhang J, Wu J, Li Y, Piao Y, Pan L, Xiang R, Yue SAbstract The concept of breast-conserving surgery is a remarkable achievement of breast cancer therapy. Neoadjuvant chemotherapy is being used increasingly to shrink the tumor prior to surgery. Neoadjuvant...
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Cellular Senescence Variation by Metabolic and Epigenomic Remodeling.: Related ArticlesCellular Senescence Variation by Metabolic and Epigenomic Remodeling.Trends Cell Biol. 2020 Sep 23;:Authors: Nakao M, Tanaka H, Koga TAbstract Cellular senescence is a state of permanent cell cycle arrest accompanied by unique secretory actions, which influences tissue formation, tumor suppression and aging in vivo. Recent evidences suggest that metabolic and epigenomic reprogram cooperatively creates...
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EGFR exon 20 insertions in advanced non-small cell lung cancer: A new history begins.: Related ArticlesEGFR exon 20 insertions in advanced non-small cell lung cancer: A new history begins.Cancer Treat Rev. 2020 Sep 14;90:102105Authors: Remon J, Hendriks LEL, Cardona AF, Besse BAbstract Although targeted therapy is standard of care in a large subset of oncogenic addicted non-small cell lung cancers (NSCLC), until recently, this therapeutic approach has not been feasible for all genomic alterations...
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Molecular correlates of cisplatin-based chemotherapy response in muscle invasive bladder cancer by integrated multi-omics analysis.: Related ArticlesMolecular correlates of cisplatin-based chemotherapy response in muscle invasive bladder cancer by integrated multi-omics analysis.Nat Commun. 2020 Sep 25;11(1):4858Authors: Taber A, Christensen E, Lamy P, Nordentoft I, Prip F, Lindskrog SV, Birkenkamp-Demtröder K, Okholm TLH, Knudsen M, Pedersen JS, Steiniche T, Agerbæk M, Jensen JB, Dyrskjøt LAbstract...
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Selecting suitable reference genes for qPCR normalization: a comprehensive analysis in MCF-7 breast cancer cell line.: Related ArticlesSelecting suitable reference genes for qPCR normalization: a comprehensive analysis in MCF-7 breast cancer cell line.BMC Mol Cell Biol. 2020 Sep 25;21(1):68Authors: Jain N, Nitisa D, Pirsko V, Cakstina IAbstract BACKGROUND: MCF-7 breast cancer cell line is undoubtedly amongst the most extensively studied patient-derived research models, providing pivotal...
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Development of the SPARK family member web pages to improve symptom management for pediatric patients receiving cancer treatments.: Related ArticlesDevelopment of the SPARK family member web pages to improve symptom management for pediatric patients receiving cancer treatments.BMC Cancer. 2020 Sep 25;20(1):923Authors: Watling CZ, McCarthy C, Theodorakidis A, Cook S, Vettese E, Schechter T, Abubeker H, Dupuis LL, Sung LAbstract BACKGROUND: Supportive care Prioritization, Assessment and Recommendations...
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Syk Inhibitors: New Computational Insights into Their Intraerythrocytic Action in Plasmodium falciparum Malaria.: Related ArticlesSyk Inhibitors: New Computational Insights into Their Intraerythrocytic Action in Plasmodium falciparum Malaria.Int J Mol Sci. 2020 Sep 23;21(19):Authors: Marchetti G, Dessì A, Dallocchio R, Tsamesidis I, Pau MC, Turrini FM, Pantaleo AAbstract Resistance to antimalarial drugs has spread rapidly over the past few decades. The WHO recommends artemisinin-based combination...
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Overexpression of wild type or a Q311E mutant MB21D2 promotes a pro-oncogenic phenotype in HNSCC.: Related ArticlesOverexpression of wild type or a Q311E mutant MB21D2 promotes a pro-oncogenic phenotype in HNSCC.Mol Oncol. 2020 Sep 26;:Authors: Gracilla DE, Korla PK, Lai MT, Chiang AJ, Liou WS, Sheu JJAbstract Cadherin-mediated cell-cell contacts regulated by intracellular binders play critical roles in tissue homeostasis and tumorigenesis. Here, we screened mutational profiles of 312 annotated...
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Toll-like receptor 4 mediates the development of fatigue in the murine Lewis Lung Carcinoma model independently of activation of macrophages and microglia.: Related ArticlesToll-like receptor 4 mediates the development of fatigue in the murine Lewis Lung Carcinoma model independently of activation of macrophages and microglia.Psychoneuroendocrinology. 2020 Sep 16;122:104874Authors: Vichaya EG, Ford BG, Quave CB, Rishi MR, Grossberg AJ, Dantzer RAbstract Cancer-related fatigue at the time...
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The use of medical modeling in microvascular free tissue transfer reconstruction with osseointegrated implantation in complex midface defects.: Related ArticlesThe use of medical modeling in microvascular free tissue transfer reconstruction with osseointegrated implantation in complex midface defects.Oral Oncol. 2020 Sep 23;110:104982Authors: Tamaki A, Seim NB, Valentin S, Ozer E, Agrawal A, VanPutten M, Kang SY, Old MOAbstract Osseointegrated implants in conjunction with microvascular free...
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A survey of personal protective equipment use among US otolaryngologists during the COVID-19 pandemic.: Related ArticlesA survey of personal protective equipment use among US otolaryngologists during the COVID-19 pandemic.Am J Otolaryngol. 2020 Sep 18;41(6):102735Authors: Yu K, Micco AG, Ference E, Levy JM, Smith SSAbstract OBJECTIVE: Describe current practices and challenges in personal protective equipment (PPE) use among US otolaryngologists during the COVID-19 pandemic. STUDY...
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Considerations for povidone-iodine antisepsis in pediatric nasal and pharyngeal surgery during the COVID-19 pandemic.: Related ArticlesConsiderations for povidone-iodine antisepsis in pediatric nasal and pharyngeal surgery during the COVID-19 pandemic.Am J Otolaryngol. 2020 Sep 19;41(6):102737Authors: Chorney SR, Rizzi MD, Dedhia KAbstract PURPOSE: Surgeons resuming elective procedures during the COVID-19 pandemic should consider strategies to mitigate risk of exposure. For otolaryngologists...
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Early voice therapy for unilateral vocal fold paralysis improves subglottal pressure and glottal closure.: Related ArticlesEarly voice therapy for unilateral vocal fold paralysis improves subglottal pressure and glottal closure.Am J Otolaryngol. 2020 Sep 13;41(6):102727Authors: Miyata E, Miyamoto M, Shiromoto O, Kobayashi Y, Yagi M, Kitawaki T, Kawaura T, Tomoda K, Iwai HAbstract PURPOSE: In cases of unilateral vocal fold paralysis (UVFP), voice disorders caused by glottic insufficiency...
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A pilot study on pediatric mononucleosis presenting with abscess.: Related ArticlesA pilot study on pediatric mononucleosis presenting with abscess.Am J Otolaryngol. 2020 Sep 10;41(6):102716Authors: Levi JM, Nassif SJ, Shetty K, McKee-Cole KM, Barth PCAbstract CONTEXT: To describe this new clinical entity, diagnosis, and potential management of pediatric intratonsillar/peritonsillar abscesses in children affected by infectious mononucleosis. METHODS: After institutional review board...
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Robot-assisted epiglottopexy as a method for managing adult obstructive sleep apnea.: Related ArticlesRobot-assisted epiglottopexy as a method for managing adult obstructive sleep apnea.Am J Otolaryngol. 2020 Sep 18;41(6):102742Authors: Shehan JN, Du E, Cohen MBAbstract INTRODUCTION: Patients who do not tolerate continuous positive airway pressure (CPAP) for treatment of obstructive sleep apnea (OSA) often seek surgical management. A variety of procedures exist to address the nasal passages,...
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Management of squamous cell carcinoma of the temporal bone: long-term results and factors influencing outcomes.: Related ArticlesManagement of squamous cell carcinoma of the temporal bone: long-term results and factors influencing outcomes.Eur Arch Otorhinolaryngol. 2020 Sep 26;:Authors: Piras G, Grinblat G, Albertini R, Sykopetrites V, Zhong SX, Lauda L, Sanna MAbstract OBJECTIVE: Temporal bone squamous cell carcinoma (TBSCC) is a rare, aggressive tumor. Surgery, alone or combined with...
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Enhanced Optimization Of Volumetric Modulated Arc Therapy Plans Using Monte Carlo Generated Beamlets.: Related ArticlesEnhanced Optimization Of Volumetric Modulated Arc Therapy Plans Using Monte Carlo Generated Beamlets.Med Phys. 2020 Sep 26;:Authors: Mathews J, French S, Bhagroo S, Pant A, Nazareth DPAbstract PURPOSE: A TPS produces VMAT plans by applying an optimization process to an objective function, followed by an accurate calculation of the final, deliverable dose. However, during...
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Evaluating Patient Benefit From Laryngochondroplasty.: Related ArticlesEvaluating Patient Benefit From Laryngochondroplasty.Laryngoscope. 2020 Sep 26;:Authors: Tang CGAbstract OBJECTIVES/HYPOTHESIS: To elucidate and review current literature on the surgical technique for laryngochondroplasty in male-to-female transgender patients. To determine the degree of benefit afforded to male-to-female transgender patients by laryngochondroplasty using the Glasgow Benefit Inventory (GBI). Study Design...
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Management of odontogenic infections and sepsis: an update.: Related ArticlesManagement of odontogenic infections and sepsis: an update.Br Dent J. 2020 Sep;229(6):363-370Authors: Jevon P, Abdelrahman A, Pigadas NAbstract The management of odontogenic infections has improved over recent decades, but further improvements are still required. The ongoing education of GDPs and their dental teams on this issue continues to be important, especially during the current COVID-19 pandemic, where remote...
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Is there evidence that radiotherapy for head and neck cancer influences the incidence of dental caries?: Related ArticlesIs there evidence that radiotherapy for head and neck cancer influences the incidence of dental caries?Evid Based Dent. 2020 Sep;21(3):116-117Authors: Araújo Andrade SAbstract Data sources Six databases (MEDLINE, EMBASE, CENTRAL, ProQuest, Scopus and Web of Science) and two trial registries (ICTRP, ClinicalTrials.gov) were searched from their inception to May 2019 using...
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Impairment of synaptic plasticity and novel object recognition in the hypergravity-exposed rats.: Related ArticlesImpairment of synaptic plasticity and novel object recognition in the hypergravity-exposed rats.Sci Rep. 2020 Sep 25;10(1):15813Authors: Lee J, Jang D, Jeong H, Kim KS, Yang SAbstract The gravity is necessary for living organisms to operate various biological events including hippocampus-related functions of learning and memory. Until now, it remains inconclusive how altered...
08:27
Betahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial.: Related ArticlesBetahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial.Braz J Otorhinolaryngol. 2020 Sep 12;:Authors: Sayin I, Koç RH, Temirbekov D, Gunes S, Cirak M, Yazici ZMAbstract INTRODUCTION: Benign paroxysmal positional vertigo is a common vestibular disorder that...
08:26
Quality of care in dysphagia patients: adaptation and validation of the Swedish SWAL-CARE questionnaire.: Related ArticlesQuality of care in dysphagia patients: adaptation and validation of the Swedish SWAL-CARE questionnaire.Health Qual Life Outcomes. 2020 Sep 25;18(1):316Authors: Hedström J, Johansson M, Olsson C, Tuomi L, Finizia CAbstract BACKGROUND: The aim of this study was to adapt the instrument and evaluate the psychometric properties of the Swedish version of the Swallowing Quality...
08:25
A unique radioprotective effect of resolvin E1 reduces irradiation-induced damage to the inner ear by inhibiting the inflammatory response.: Related ArticlesA unique radioprotective effect of resolvin E1 reduces irradiation-induced damage to the inner ear by inhibiting the inflammatory response.Radiat Oncol. 2020 Sep 25;15(1):223Authors: Zhang J, Xu A, Niu T, Liu C, Zhang Y, Li T, Wang J, Wang Y, Sun DAbstract BACKGROUND: In addition to the direct effects of irradiation, the induced inflammatory...
08:14
In Vitro Studies to Define the Cell-Surface and Intracellular Targets of Polyarginine-Conjugated Sodium Borocaptate as a Potential Delivery Agent for Boron Neutron Capture Therapy.: Related ArticlesIn Vitro Studies to Define the Cell-Surface and Intracellular Targets of Polyarginine-Conjugated Sodium Borocaptate as a Potential Delivery Agent for Boron Neutron Capture Therapy.Cells. 2020 Sep 23;9(10):Authors: Fujimura A, Yasui S, Igawa K, Ueda A, Watanabe K, Hanafusa T, Ichikawa Y, Yoshihashi S,...
08:14
Intra-Operative Detection of a Left-Sided Non-Recurrent Laryngeal Nerve during Vagus Nerve Stimulator Implantation.: Related ArticlesIntra-Operative Detection of a Left-Sided Non-Recurrent Laryngeal Nerve during Vagus Nerve Stimulator Implantation.Medicina (Kaunas). 2020 Sep 23;56(10):Authors: Labuschagne JJ, Hammer NAbstract Left sided non-recurrent laryngeal nerves (NRLN) are very rarely observed during surgery in the head and neck region. Arising directly from the cervical aspect of...
08:13
An Adult Case of Hemifacial Spasm as the Predominant Manifestation of Spontaneous Intracranial Hypotension.: Related ArticlesAn Adult Case of Hemifacial Spasm as the Predominant Manifestation of Spontaneous Intracranial Hypotension.Headache. 2020 Sep 26;:Authors: Chow CY, Harrison N, Fermo OPPMID: 32979212 [PubMed - as supplied by publisher]The demonstration of a spinal CSF leak (ie, the presence of extrathecal CSF) is sufficient to diagnose spontaneous intracranial hypotension, regardless of associated...
08:11
SARS-CoV-2 Infection and COVID-19 in 5 Patients in Ecuador After Prior Treatment with Hydroxychloroquine for Systemic Lupus Erythematosus.: Related ArticlesSARS-CoV-2 Infection and COVID-19 in 5 Patients in Ecuador After Prior Treatment with Hydroxychloroquine for Systemic Lupus Erythematosus.Am J Case Rep. 2020 Sep 26;21:e927304Authors: Zurita MF, Iglesias Arreaga A, Luzuriaga Chavez AA, Zurita LAbstract BACKGROUND This case series describes 5 patients with SARS-CoV-2 infection and COVID-19...
08:08
Pegvisomant in combination or pegvisomant alone after failure of somatostatin analogs in acromegaly patients: an observational French ACROSTUDY cohort study: AbstractObjectiveAfter surgery, when somatostatin analogs (SAs) do not normalise IGF-I, pegvisomant (PEG) is indicated. Our aim was to define the medical reasons for the treatment of patients with PEG as monotherapy (M) or combined with SA, either as primary bitherapy, PB (PEG is secondarily introduced after SA) or as secondary bitherapy, SB...
08:07
A Case of Guillain-Barré Syndrome Associated With COVID-19: Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. A novel member of human RNA coronavirus, which is an enveloped betacoronavirus, has been termed severe acute respiratory syndrome coronavirus-2 (SARS COV-2). The illness caused by SARS COV-2 is referred to as the coronavirus disease 2019 (COVID-19). It is a highly contagious disease that has resulted in a global pandemic. The clinical spectrum...
08:06
Vitreous haemorrhage caused by unusual giant macular tear: a case report: Journal of International Medical Research, Volume 48, Issue 9, September 2020. Macular tears rarely occur without trauma. Here, we describe a patient with vitreous haemorrhage, which was caused by an unusual giant macular tear secondary to existing branch retinal vein occlusion. A 60-year-old woman presented with vision loss in the right eye because of vitreous haemorrhage. She had a history of branch retinal vein occlusion...
08:05
Imaging features of neonatal systemic juvenile xanthogranuloma: a case report and review of the literature: Journal of International Medical Research, Volume 48, Issue 9, September 2020. Juvenile xanthogranuloma (JXG) is the most common non-Langerhans cell histiocytic disorder in children. This report describes the case of a 28-day-old boy that presented with multiple subcutaneous nodular lesions on the trunk and extremities, and multiple red nodular lesions on the scrotum. Magnetic resonance imaging...
08:03
Cohabitation, infection and breast cancer risk: AbstractFor 50 years the effect of age at first birth (AFB) has been thought to explain the strong association between breast cancer risk and age at first marriage (AFM), which was first reported in 1926. The independent effects of AFM, AFB and number of sexual partners adjusted for parity and other risk factors were estimated in reanalysis of a large international case‐control study conducted in 1979‐82 (2,274 breast cancers, 18,209 controls) by unconditional...
08:02
Prognostic Significance of Post‐Surgery Circulating Tumor DNA in Non‐Metastatic Colorectal Cancer: Individual Patient Pooled Analysis of Three Cohort Studies: ABSTRACTStudies in multiple solid tumor types have demonstrated the prognostic significance of ctDNA analysis after curative intent surgery. A combined analysis of data across completed studies could further our understanding of circulating tumor DNA (ctDNA) as a prognostic marker and inform future trial design. We combined individual patient...
08:01
Polaprezinc for prevention of oral mucositis in patients receiving chemotherapy followed by hematopoietic stem cell transplantation: a multi‐institutional randomized controlled trial: AbstractOral mucositis is a common and distressing complication in patients receiving high‐dose chemotherapy followed by hematopoietic stem cell transplantation (HSCT). We reported previously in a single‐center retrospective analysis that zinc‐L‐carnosine (polaprezinc, PZ) reduced the incidence of oral mucositis associated...
08:01
Establishment of PDX‐derived salivary adenoid cystic carcinoma cell lines using organoid culture method: AbstractTo generate a reliable preclinical model system exhibiting the molecular features of salivary adenoid cystic carcinoma (ACC) whose biology is still unclear due to the paucity of stable cell cultures. To develop new in vitro and in vivo models of ACC, the techniques of organoid culture and patient‐derived tumor xenograft (PDX), which have attracted attention in other malignancies in recent...
08:00
ASPIRIN AND THE RISK OF NON‐DIGESTIVE TRACT CANCERS: AN UPDATED META‐ANALYSIS TO 2019: ABSTRACTAspirin has been associated to a reduced risk of colorectal and other selected digestive tract cancers, but the evidence other neoplasms is still controversial. In order to provide an up‐to‐date quantification of the role of aspirin on lung, breast, endometrium, ovary, prostate, bladder, and kidney cancer, we conducted a systematic review and meta‐analysis of all observational studies published up to March...
07:51
PharmaceuticsPharmaceutics, Vol. 12, Pages 925: Positron Emission Tomography in the Inflamed Cerebellum: Addressing Novel Targets among G Protein-Coupled Receptors and Immune ReceptorsPharmaceutics, Vol. 12, Pages 925: Positron Emission Tomography in the Inflamed Cerebellum: Addressing Novel Targets among G Protein-Coupled Receptors and Immune Receptors Pharmaceutics doi: 10.3390/pharmaceutics12100925 Authors: Margit Pissarek Inflammatory processes preceding clinical manifestation of brain diseases...
07:51
MicroorganismsMicroorganisms, Vol. 8, Pages 1489: Elimination of Extracellular Adenosine Triphosphate for the Rapid Prediction of Quantitative Plate Counts in 24 h Time-Kill Studies against Carbapenem-Resistant Gram-Negative BacteriaMicroorganisms, Vol. 8, Pages 1489: Elimination of Extracellular Adenosine Triphosphate for the Rapid Prediction of Quantitative Plate Counts in 24 h Time-Kill Studies against Carbapenem-Resistant Gram-Negative Bacteria Microorganisms doi: 10.3390/microorganisms8101489...
07:51
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 7152: Neuroprotective Effect of Antioxidants in the BrainIJMS, Vol. 21, Pages 7152: Neuroprotective Effect of Antioxidants in the Brain International Journal of Molecular Sciences doi: 10.3390/ijms21197152 Authors: Kyung Hee Lee Myeounghoon Cha Bae Hwan Lee The brain is vulnerable to excessive oxidative insults because of its abundant lipid content, high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS)...
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DiversityDiversity, Vol. 12, Pages 374: Limnological Characteristics and Diatom Dominants in Lakes of Northeastern PolandDiversity, Vol. 12, Pages 374: Limnological Characteristics and Diatom Dominants in Lakes of Northeastern Poland Diversity doi: 10.3390/d12100374 Authors: Monika Eliasz-Kowalska Agata Z. Wojtal Determination of the relationships between environmental factors and diatom assemblages is usually made for several hundred lakes spread over a large area. However, the analysis of several...
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AntibioticsAntibiotics, Vol. 9, Pages 651: Acquisition Risk Factors of the SCCmec IX-Methicillin-Resistant Staphylococcus aureus in Swine Production Personnel in Chiang Mai and Lamphun Provinces, ThailandAntibiotics, Vol. 9, Pages 651: Acquisition Risk Factors of the SCCmec IX-Methicillin-Resistant Staphylococcus aureus in Swine Production Personnel in Chiang Mai and Lamphun Provinces, Thailand Antibiotics doi: 10.3390/antibiotics9100651 Authors: Peerapat Rongsanam Terdsak Yano Wuttipong Yokart...
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▼ Σεπτεμβρίου (110)
- International Journal of Molecular SciencesIJMS...
- Obesity and Hair Cortisol: Relationships Varied B...
- Influence of Personality and Attitude Towards Lo...
- Evaluation of confirmatory data following the Art...
- Combining Clinical and MR Data for Diagnosis of Ly...
- Factors of Adjacent Segment Disease Onset After Mi...
- Association between stroke lesions and videofluoro...
- A small mass on the palmar surface of hand, which ...
- Radical surgery for primary thyroid lymphoma
- Synchronous sigmoid and transverse volvulus
- Enteroatmospheric fistula (EAF)
- A 21-year-old male with a solitary palpable tumoro...
- Perioperative FOLFOX in management of peritoneal m...
- Worsening abdominal pain, fever and nausea
- Hepatic artery aneurysm
- Anorectal malignant melanoma in the transitional z...
- Covering a large abdominal wall defect using bilat...
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- Interpositional collagenated cancellous bone block...
- St Andrew's COVID-19 surgery safety (StACS) study:...
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- A horse of a different colour: distinct mechanisms...
- YAP signaling induces PIEZO1 to promote oral squam...
- Effect of highly effective modulator therapy on qu...
- Transcervical endoscopic retropharyngeal lymph nod...
- The association among swallowing function, hand gr...
- Polyamines in the Virulence of Bacterial Pathogens...
- Why COVID-19 is less frequent and severe in children
- Is dental caries associated with lower respiratory...
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- Bladder preservation therapy for muscle invasive b...
- Ventriculoatrial and ventriculopleural shunts as s...
- Brain Structural Changes in Focal Dystonia-What Ab...
- Performance of cochlear implant recipients fitted ...
- The Penetration-Aspiration Scale (PAS)
- Predictable toxicities with futures immunotherapie...
- Oncogenetic consultation
- Dosimetric factors related to postoperative pulmon...
- New European approvals: Alpelisib for HRpos/HER2ne...
- Within otolaryngology, lumbar drains are most freq...
- Staging and Treatment of Colorectal Cancer
- Arterial Trauma.
- Prevalence of photoparoxysmal response in patients...
- Treatment of epileptic women of childbearing age w...
- The efficacy of assisted reproductive treatment in...
- Giant hypothalamic hamartoma associated with an im...
- Blue light photoactivated riboflavin modified univ...
- Nightmares
- The antibiotic deschloro-chlorotricin (DCCT)
- Overexpressed sFRP3 exerts an inhibitory effect on...
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- Metabolic and epigenomic reprogram cooperatively c...
- EGFR exon 20 insertions in advanced non-small cell...
- Molecular correlates of cisplatin-based chemothera...
- Reference genes for qPCR normalization: a comprehe...
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- Povidone-iodine antisepsis in pediatric nasal and ...
- Early voice therapy for unilateral vocal fold para...
- Pediatric mononucleosis presenting with abscess.
- Robot-assisted epiglottopexy as a method for manag...
- Management of squamous cell carcinoma of the tempo...
- Enhanced Optimization Of Volumetric Modulated Arc ...
- Laryngochondroplasty in male-to-female transgender...
- Management of odontogenic infections and sepsis
- There is an incidence of approximately 29% of dent...
- The gravity is necessary for living organisms to o...
- Betahistine add-on therapy for treatment of subjec...
- SWAL-CARE questionnaire.
- Resolvin E1 reduces irradiation-induced damage to ...
- Polyarginine-Conjugated Sodium Borocaptate as a Po...
- Left-Sided Non-Recurrent Laryngeal Nerve
- An Adult Case of Hemifacial Spasm as the Predomina...
- SARS-CoV-2 Infection in Patients After Prior Treat...
- Pegvisomant in combination or pegvisomant alone af...
- fever, fatigue, dry cough, dyspnea, and diarrhea,G...
- Vitreous haemorrhage caused by unusual giant macul...
- Juvenile xanthogranuloma (JXG) is the most common ...
- Cohabitation, infection and breast cancer risk
- Prognostic Significance of Post‐Surgery Circulatin...
- Polaprezinc for prevention of oral mucositis
- the molecular features of salivary adenoid cystic ...
- Aspirin has been associated to a reduced risk of c...
- PharmaceuticsPharmaceutics, Vol. 12, Pages 925:...
- MicroorganismsMicroorganisms, Vol. 8, Pages 148...
- International Journal of Molecular SciencesIJMS,...
- DiversityDiversity, Vol. 12, Pages 374: Limnolog...
- AntibioticsAntibiotics, Vol. 9, Pages 651: Acqui...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,