Mediators of Inflammation,The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs)Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate substrates by enzymatic cleavage and, on the basis of their activities, have been demonstrated to play a role in ageing. Thus, in order to gain insight into the pathophysiology of ageing and to identify new markers of longevity, we analysed the activity levels...
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Mitochondrial energy metabolism is negatively regulated by cannabinoid receptor 1 in intact human epidermis: AbstractEpidermal energy metabolism is relevant to skin physiology, aging, and photodamage. While selected hormones stimulate epidermal keratinocyte mitochondrial activity, its negative regulation remains unknown. In several cell types, cannabinoid receptor 1 (CB1) is expressed both in the cell membrane (cmCB1), and in the mitochondrial outer membrane (mtCB1), where its stimulation directly...
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Wiley: Dermatologic Therapy: Performing dermoscopy in the COVID‐19 pandemicWiley: Dermatologic Therapy: Table of ContentsTue May 05, 2020 20:03Association between prognosis and complete resection in primary cutaneous myoepithelial carcinoma: two case presentations and literature reviewAbstract Myoepithelial carcinoma is a rare tumor that occurs in the salivary glands. Therefore, primary cutaneous myoepithelial carcinoma is extremely rare. The malignancy of this tumor is due to its aggressive nature...
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Spinal Intramedullary Epidermoid Cyst: Case Report and Updated Literature Review: Publication date: July 2020Source: World Neurosurgery, Volume 139Author(s): Octavian-Mihai Sîrbu, Alin-Vasile Chirteş, Marian Mitricã, Carmen-Adella Sîrbu
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Beetroot juice lowers blood pressure and improves endothelial function in pregnant eNOS−/− mice: importance of nitrate‐independent effects: More imagesBeetrootVegetableDescriptionThe beetroot is the taproot portion of a beet plant, usually known in Canada and the USA as beets while the vegetable is referred to as beetroot in British English, and also known as the table beet, garden beet, red beet, dinner beet or golden beet. WikipediaNutrition FactsBeetsBeets, boiledBeetsAmount Per 1 beet (2" dia)...
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American Journal of Physical Anthropology,Concerning data sharing in biological anthropologyAmerican Journal of Physical AnthropologyTue May 05, 2020 18:08Enamel growth rates of anterior teeth in males and females from modern and ancient British populationsAbstract Objective This study explored biological sex differences in the regional daily growth rates of human anterior enamel from modern and ancient populations in Britain. Methods Maxillary permanent incisors (n = 80) and canines (n = 69) from...
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bioRxiv Subject Collection: Evolutionary Biology,Organ-specific propensity drives patterns of gene expression evolution [NEW RESULTS]The origins of multicellular physiology are tied to evolution of gene expression. Genes can shift expression as organisms evolve, but how ancestral expression influences altered descendant expression is not well understood. To examine this, we amalgamated 1,903 RNA-seq datasets from 182 research projects, including 6 organs in 21 vertebrate species. Quality control...
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Magnetic Resonance Imaging,Multi-parametric MRI of the physiology and optics of the <em>in-vivo</em> mouse lensPublication date: Available online 5 May 2020Source: Magnetic Resonance ImagingAuthor(s): Eric R. Muir, Xingzheng Pan, Paul J. Donaldson, Ehsan Vaghefi, Zhao Jiang, Caterina Sellitto, Thomas W. WhiteMagnetic Resonance ImagingTue May 05, 2020 20:36Mark above section as read
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ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy, Photodynamic performance of amphiphilic chlorin e6 derivatives with appropriate properties: A comparison between different-type liposomes as delivery systemsPublication date: Available online 5 May 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Agnieszka Szurko, Marzena Rams-Baron, Franz-Peter Montforts, Daniela Bauer, Patrycja Kozub, Jerzy Gubernator, Sandra Altmann, Agata Stanek, Aleksander Sieroń, Alicja RatusznaScienceDirect...
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Evolutionary Biology News -- Electrical activity in living organisms mirrors electrical fields in atmosphereA new study provides evidence for a direct link between electrical fields in the atmosphere and those found in living organisms, including humans.Evolutionary Biology News -- ScienceDailyTue May 05, 2020 19:16Overlapping versions of our genetic history complicate precision medicineThe promise of personalized medicine has not fully materialized, say researchers, because the full sophistication...
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Gait & Posture,Major factors influencing rearfoot external eversion moment during barefoot walkingPublication date: Available online 5 May 2020Source: Gait & PostureAuthor(s): Norio Tsujimoto, Hiroyuki Nunome, Yasuo IkegamiGait & PostureTue May 05, 2020 21:06The immediate effects of a shoulder brace on muscle activity and scapular kinematics in subjects with shoulder impingement syndrome and rounded shoulder posture: A randomized crossover designPublication date: Available online 4 May...
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Ultrasound in Medicine & Biology,Ultrasound Definitions and Findings in Greater Trochanteric Pain Syndrome: A Systematic ReviewPublication date: Available online 5 May 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Mads Hilligsøe, Michael Skovdal Rathleff, Jens Lykkegaard OlesenUltrasound in Medicine & BiologyTue May 05, 2020 21:32<em>In vivo</em> Ultrafast Quantitative Ultrasound and Shear Wave Elastography Imaging on Farm-Raised Duck Livers during Force FeedingPublication...
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Latest Results for Radiation and Environmental Biophysics,Eurados review of retrospective dosimetry techniques for internal exposures to ionising radiation and their applicationsAbstract This work presents an overview of the applications of retrospective dosimetry techniques in case of incorporation of radionuclides. The fact that internal exposures are characterized by a spatially inhomogeneous irradiation of the body, which is potentially prolonged over large periods and variable over time, is...
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Case Reports in Pathology,Hydrocele of the Canal of Nuck with Endometriosis: Right-Side Dominance Confirmed by Literature Review and Statistical AnalysisIntroduction. The canal of Nuck is an embryological remnant of the peritoneal pouch that extends into the labium majus of women. Hydrocele is the most common presentation, but only a small number of cases are reported in association with endometriosis. Case Presentation. The patient is a 45-year-old woman who presented with left inguinal mass with...
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Description and relationships of the parotid gland levels proposed by the European Salivary Gland Society staging system: an anatomical study: AbstractObjectivesTo perform an anatomical study to analyze the size, weight, and the relationships of the parotid levels proposed by the European Salivary Gland Society (ESGS).Materials and methodsAnatomical dissections of the parotid region in 19 human specimens were performed. All dissections were systematically carried out to study the dimensions and weight...
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Journal of Cancer Research and Clinical Oncology,Feasibility and safety of 1.5 T MR-guided and daily adapted abdominal-pelvic SBRT for elderly cancer patients: geriatric assessment tools and preliminary patient-reported outcomesAbstract Background We present preliminary data of the first older cancer patients treated with Hybrid Linac for stereotactic body radiotherapy (SBRT) consisting of 1.5 T MRI-guided and daily-adapted treatment. The aim was to assess feasibility, safety and the role of G8...
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Active HPV infection and its influence on survival in head and neck squamous-cell cancer: AbstractPurposeHPV is involved in the development of some head and neck squamous-cell carcinomas (HNSCC). It was suggested that only transcriptionally active virus can induce carcinogenesis, therefore, the aim of our study was to analyze the frequency of active HPV infection, virus type, and its prognostic role in HNSCC patients.MethodsStatus of active HPV infection was assessed for 155 HNSCC patients based...
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Latest Results for Current Microbiology,Rudanella paleaurantiibacter sp. nov., Isolated from Activated SludgeAbstract A Gram-stain-negative, orange-colored bacterium, designated HX-22-17T, was isolated from activated sludge of an agricultural chemical plant in Maanshan, Anhui province, China (118° 52′ E 31° 68′ N). The strain was strictly aerobic, non-endospore forming, non-motile, and ellipse. Growth of the strain was observed at 16–42 °C (optimum between 25 and 30 °C) at pH 6.0–9.0 (optimum at...
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Neuropilin-2 promotes growth and progression of papillary thyroid cancer cells: Publication date: Available online 4 May 2020Source: Auris Nasus LarynxAuthor(s): Geonho Lee, Yea Eun Kang, Chan Oh, Lihua Liu, Yanli Jin, Mi Ae Lim, Ho-Ryun Won, Jae Won Chang, Bon Seok Koo
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JoVE: Journal of Visualized Experiments,Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived CardiomyocytesWe present a model of ischemic heart disease using cardiomyocytes derived from human induced pluripotent stem cells, together with a method for quantitative evaluation of tissue damage caused by ischemia. This model can provide a useful platform for drug screening and further research on ischemic heart disease.JoVE: Journal of Visualized...
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Genetic variants of the peroxisome proliferator‐activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer: AbstractBecause the peroxisome proliferator‐activated receptor (PPAR) signaling pathway is involved in development and progression of pancreatic cancer, we investigated associations between genetic variants of the PPAR pathway genes and pancreatic cancer risk by using three published genome‐wide association study datasets including 8477 cases and 6946 controls of European...
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Lymphocyte-to-monocyte ratio prior to radioiodine ablation in low- and intermediate-risk, papillary thyroid cancer: AbstractPurposeWe aimed to investigate inflammation indices based on preablation hematological parameter of the lymphocyte-to-monocyte ratio (LMR) to predict the clinical outcome in papillary thyroid cancer (PTC) patients with low- and intermediate-risk stratification.MethodsThis retrospective study analyzed 772 patients with low- and intermediate-risk PTC who underwent total thyroidectomy...
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Periprostatic paraganglioma causing occult Cushing's syndrome: References1.S.T. Sharma; AACE Adrenal Scientific Committee, An individualized approach to the evaluation of Cushing syndrome. Endocr. Pract. 23(6), 726–737 (2017). https://doi.org/10.4158/EP161721.RAArticlePubMedGoogle Scholar2.N.A. Wagner-Bartak, A. Bajomy, M.A. Habra, S.H. Mukhi, A.C. Morani, B.R. Korivi et al. Cushing syndrome: diagnostic workup and imaging features, with clinical and pathologic correlation. AJR Am. J. Roentgenol. 209(1),...
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International journal of basic and clinical endocrinology,The novel founder homozygous V225M mutation in the HSD17B3 gene causes aberrant splicing and XY-DSDAbstract Purpose Mutations in the gene HSD17B3 encoding the 17-beta hydroxysteroid dehydrogenase 3 enzyme cause testosterone insufficiency leading to XY disorders of sex development. In this study the clinical and molecular characteristics of three patients from consanguineous families are elucidated. Methods We identified three patients from...
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Imaging,Enhancing clinician and patient understanding of radiology reports: a scoping review of international guidelinesAbstract Imaging reports are the primary method of communicating diagnostic imaging findings between the radiologist and the referring clinician. Guidelines produced by professional bodies provide guidance on content and format of imaging reports, but the extent to which they consider comprehensibility for referring clinicians and their patients is unclear. The objective of this...
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Latest Results for Abdominal Radiology,Diagnostic performance of commercially available vs. in-house radiomics software in classification of CT images from patients with pancreatic ductal adenocarcinoma vs. healthy controlsAbstract Purpose The purpose of this study is to evaluate diagnostic performance of a commercially available radiomics research prototype vs. an in-house radiomics software in the binary classification of CT images from patients with pancreatic ductal adenocarcinoma (PDAC) vs....
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Improved robust tensor principal component analysis for accelerating dynamic MR imaging reconstruction: AbstractDynamic magnetic resonance imaging (dMRI) strikes a balance between reconstruction speed and image accuracy in medical imaging field. In this paper, an improved robust tensor principal component analysis (RTPCA) method is proposed to reconstruct the dynamic magnetic resonance imaging (MRI) from highly under-sampled K-space data. The MR reconstruction problem is formulated as a high-order...
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Neurosurgical management of brain and spine tumors in the COVID-19 era: an institutional experience from the epicenter of the pandemic: AbstractThe challenges of neurosurgical patient management and surgical decision-making during the 2019–2020 COVID-19 worldwide pandemic are immense and never-before-seen in our generation of neurosurgeons. In this case-based formatted report, we present the Mount Sinai Hospital (New York, NY) Department of Neurosurgery institutional experience in the epicenter of...
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Therapeutic Hypothermia in Acute Ischemic Stroke—a Systematic Review and Meta-Analysis: AbstractPurpose of ReviewTherapeutic hypothermia (TH) in stroke demonstrates robust neuroprotection in animals but clinical applications remain controversial. We assessed current literature on the efficacy of TH in ischemic stroke.Recent FindingsWe conducted a meta-analysis comparing TH versus controls in studies published until June 2019. Controlled studies reporting on ≥ 10 adults with acute ischemic stroke...
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PD-L1 and HER2 Expression in Gastroesophageal Cancer: a Matched Case Control Study: AbstractImmunotherapy with check-point inhibitors serves as a promising treatment strategy in patients with upper gastrointestinal (GI) tumors. Human epidermal growth factor receptor 2 (HER2) is the only identified therapeutic target in upper GI tumors, whose potential interaction with programmed death-ligand 1 (PD-L1) is unknown. The aim of this study was the investigation of PD-L1 and HER2 in upper GI tumors. We...
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BioMed Research International,Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling PathwayBackground. Lanthanum (La) exposure can cause central nervous system (CNS) damage and dysfunction in children, seriously affecting intellectual development. miR-124 plays an important role in the development of the nervous system. We exposed rats to a La environment then observed the rats' learning and memory damage and neurotoxicity...
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ANZ Journal of Surgery,Sexually transmitted infective vasitis mimicking left inguinal hernia: computed tomography clarifies diagnosisANZ Journal of SurgeryTue May 05, 2020 22:56Atypical mesenteroaxial gastric volvulus with wandering spleen as a late complication of vagotomy and pyloromyotomy for peptic duodenal ulcerANZ Journal of SurgeryTue May 05, 2020 22:56Unusual case of primary cutaneous cryptococcosisANZ Journal of SurgeryTue May 05, 2020 22:56Mark above section as read
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Cancer Immunology, Immunotherapy,A gene expression-based immune signature for lung adenocarcinoma prognosisAbstract Background Lung adenocarcinoma (LUAD) has become the most frequent histologic type of lung cancer in the past several decades. Recent successes with immune checkpoint blockade therapy have demonstrated that the manipulation of the immune system is a very potent treatment for LUAD. This study aims to explore the role of immune-related genes in the development of LUAD and establish a...
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Angewandte Chemie International Edition,Rolf Huisgen's Classic Studies of Cyclic Triene Diels‐Alder Reactions Elaborated by Modern Computational AnalysisRolf Huisgen explored the Diels‐Alder reactions of 1,3,5‐cycloheptatriene (CHT) and cyclooctatetraene (COT) with dienophiles maleic anhydride and 4‐phenyl‐1,2,4‐triazoline‐3,5‐dione (PTAD) to determine the kinetics and mechanisms of various electrocyclizations and Diels‐Alder reactions. These reactions have been examined with density functional...
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Expanding Awareness of the Distribution and Biologic Potential of Ectomesenchymal Chondromyxoid Tumor: AbstractEctomesenchymal chondromyxoid tumor is a rare neoplasm of uncertain histogenesis that typically occurs in the anterior dorsal tongue. Recent reports in the literature have described rare examples of gingival, palatal and tonsillar lesions. Histologically, ectomesenchymal chondromyxoid tumors are typically well-circumscribed, lacking overtly aggressive features. Herein we report a tumor arising...
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Which Anesthesia Regimen Is Best to Reduce Pulmonary Complications After Head and Neck Surgery?: Objectives/HypothesisThe differences between intravenous and inhalation anesthesia in clinical postoperative pulmonary complications (PPCs) have been studied in cardiac and lung resection surgery. Clinical evidence for the effects of these two anesthetics on PPCs in other types of surgery is still missing. We aimed to assess the impact of sevoflurane and propofol on the incidence of PPCs in patients undergoing...
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Laryngotracheal Mucosal Surface Expression of Candidate Biomarkers in Idiopathic Subglottic Stenosis
Laryngotracheal Mucosal Surface Expression of Candidate Biomarkers in Idiopathic Subglottic Stenosis: ObjectivesIdiopathic subglottic stenosis (iSGS) is an inflammatory process leading to fibrosis and narrowing of the laryngotracheal airway. There is variability in patient response to surgical intervention, but the mechanisms underlying this variability are unknown. In this pilot study, we measure expression of candidate targets at the mucosal surface of the subglottis in iSGS patients. We aim to...
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The LaryngoscopeHow to reorgan,ize an ENT outpatient service during the COVID‐19 outbreak: report from northern ItalyThe LaryngoscopeTue May 05, 2020 21:19Which Anesthesia Regimen Is Best to Reduce Pulmonary Complications After Head and Neck Surgery?Objectives/Hypothesis The differences between intravenous and inhalation anesthesia in clinical postoperative pulmonary complications (PPCs) have been studied in cardiac and lung resection surgery. Clinical evidence for the effects of these two anesthetics...
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Cancer/Radiothérapie,Guide pratique pour la radiothérapie des hémopathies malignes dans la situation d'épidémie de covid-19 : recommandations de l'International Lymphoma Radiation Oncology GroupPublication date: Available online 4 May 2020Source: Cancer/RadiothérapieAuthor(s): Youlia KirovaCancer/RadiothérapieTue May 05, 2020 23:47Radiothérapie mammaire dans le contexte de la pandémie de covid-19: astuces pratiques en période épidémique et conseils pour la reprise de l'activité en fin de crisePublication...
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Critical Reviews in Oncology/Hematology (open access),Systematic review: Soluble immunological biomarkers in advanced non-small-cell lung cancer (NSCLC)Publication date: Available online 5 May 2020Source: Critical Reviews in Oncology/HematologyAuthor(s): Finn Mildner, Sieghart Sopper, Arno Amann, Andreas Pircher, Georg Pall, Stefan Köck, Erin Naismith, Dominik Wolf, Gabriele GamerithCritical Reviews in Oncology/Hematology (open access)00:18Challenges and opportunities of cfDNA analysis implementation...
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IL-1Rahigh-IL-4low-IL-13low: A Novel Plasma Cytokine Signature Associated with Olfactory Dysfunction in Older US Adults: AbstractInflammation has been implicated in physical frailty, but its role in sensory impairment is unclear. Given that olfactory impairment predicts dementia and mortality, determining the role of the immune system in olfactory dysfunction would provide insights mechanisms of neurosensory decline. We analyzed data from the National Social Life, Health and Aging Project, a representative...
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How the CDC plans to track the mutating coronavirus Having more sequenced samples of SARS-CoV-2 will help epidemiologists and others in the public health field better understand the profile of different strains of SARS-CoV-2, and track their spread. (NIAID/)Follow all of PopSci's COVID-19 coverage here, including tips for cleaning groceries, ways to tell if your symptoms are just allergies, and a tutorial on making your own mask.An initiative spearheaded by the Centers for Disease Control's Office...
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Journal of Voice,The Dysphonia Severity Index (DSI)—Normative Values. Systematic Review and Meta-AnalysisAs the dysphonia severity index (DSI) is used in clinical practice as a diagnostic tool, a thorough systematic review of the literature is required to assess the normative value of DSI. The main propose of present study was to determine the normative value of DSI among subjects whose voices were judged as normal.Journal of VoiceTue May 05, 2020 03:00Voice Handicap Index-Throat: Translation and...
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Clinical Ophthalmology,Anterior Segment Biometry During Accommodation and Effects of Cycloplegics by Swept-Source Optical Coherence TomographyClinical OphthalmologyTue May 05, 2020 23:57Modified Intraocular Lens Intrascleral Fixation Technique Using Two Vitrectomy Ports as Lens Haptic Fixation SitesClinical OphthalmologyTue May 05, 2020 23:56Ripasudil Hydrochloride Hydrate in the Treatment of Glaucoma: Safety, Efficacy, and Patient SelectionClinical OphthalmologyTue May 05, 2020 23:53Mark above...
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NMR‐based Tissue Metabolomic Analysis Clarifies Molecular Mechanisms of Gastric Carcinogenesis: AbstractGastric cancer (GC) is one of the deadliest cancers worldwide, and the progression of gastric carcinogenesis (GCG) covers multiple complicated pathological stages. Molecular mechanisms of GCG are still unclear. Here, we performed NMR‐based metabolomic analysis of aqueous metabolites extracted from gastric tissues in an established rat model of GCG. We showed that the metabolic profiles were clearly...
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Middle Ear and Temporal Bone Nonkeratinizing Squamous Cell Carcinomas With DEK-AFF2 Fusion: An Emerging Entity: Primary squamous cell carcinomas (SCCs) of the middle ear and temporal bone are rare and usually keratinizing by morphology. Nonkeratinizing, basaloid SCCs arising in this area are exceedingly rare, and, due to the anatomic proximity to the skull base, nasopharynx, and nasal sinuses, the differential diagnosis is broad. Most tumors with squamous differentiation arising in these subsites...
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Journal of Prosthodontics,Layperson and Dental Professional Perception When Evaluating Their Own Virtually 2D or 3D Simulated Esthetic DiscrepanciesAbstract Purpose To analyze the perceptions of laypersons, dental students, and dentists regarding disparities of the maxillary dental midline and the occlusal plane (OP) when analyzing their own 2D or 3D clinical simulation. Material and methods 20 participants per group volunteered (N = 60). Intraoral and facial scans, and a photograph were obtained...
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Complete resolution of epileptic spasms with vigabatrin in a patient with 3‐methylglutaconic aciduria caused by TIMM50 gene mutation:
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Latest Results for Applied Microbiology and Biotechnology,Expression vector cassette engineering for recombinant therapeutic production in mammalian cell systemsAbstract Human tissue plasminogen activator was the first recombinant therapy protein that successfully produced in Chinese hamster ovary cells in 1986 and approved for clinical use. Since then, more and more therapeutic proteins are being manufactured in mammalian cells, and the technologies for recombinant protein production in this expression...
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Annals of Allergy, Asthma & Immunology,How to Compare the Efficacy of Biologic Agents in AsthmaAsthma affects approximately 10% of the U.S. population and worldwide it is estimated that 300 million people are affected by this disease (www.ginaasthma.org; www.cdc.gov/asthma). One of the emerging and important aspects of asthma is its heterogeneity, which is reflected in many of its characteristics: onset of disease, severity, persistence, and responsiveness to treatment.1 The subpopulations with...
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Superior Turbinate Eosinophilia Predicts Olfactory Decline in Patients with Chronic Rhinosinusitis: Predicting the postoperative olfactory decline in patients with chronic rhinosinusitis (CRS) remains a significant challenge.
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Oral Diseases,Overactivation of the NF‐κB pathway impairs molar enamel formationAbstract Objective Hypohidrotic ectodermal dysplasia (HED) is a hereditary disorder characterized by abnormal structures and functions of the ectoderm‐derived organs, including teeth. HED patients exhibit a variety of dental symptoms, such as hypodontia. Although disruption of the EDA/EDAR/EDARADD/NF‐κB pathway is known to be responsible for HED, it remains unclear whether this pathway is involved in the process of enamel...
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Radiotherapy and Oncology,Error detection thresholds for routine real time in vivo dosimetry in HDR prostate brachytherapyIn high dose rate (HDR) prostate brachytherapy metal or plastic needles are implanted into the prostate gland through the perineum and the treatment is delivered using a single radioactive source driven by a remote afterloader. The dwell positions where the source stops within each needle, and the dwell time that the source stops at each dwell position, are optimised to deliver...
09:30
bioRxiv Subject Collection: Evolutionary Biology,The insertion of a mitochondrial selfish element into the nuclear genome and its consequences [NEW RESULTS]Homing endonucleases (HE) are enzymes capable of cutting DNA at highly specific target sequences, the repair of the generated double-strand break resulting in the insertion of the HE-encoding gene ("homing" mechanism). HEs are present in all three domains of life and viruses; in eukaryotes, they are mostly found in the genomes of mitochondria...
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Dentoskeletal effects of the maxillary splint headgear in the early correction of Class II malocclusion: To compare dentoskeletal changes produced by the maxillary splint headgear and cervical headgear appliance during the early phase of Class II treatment, specially the initial overjet and upper incisors position.
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Oligometastasis and local ablation in the era of systemic targeted and immunotherapy: During these last years, new agents have dramatically improved the survival of the metastatic patients. Oligometastases represent a continuous field of interest in which the integration of metastases-directed ...
09:29
Inflammation as a risk factor for stroke in atrial fibrillation: data from a microarray data analysis: Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveStroke is a severe complication of atrial fibrillation (AF). We aimed to discover key genes and microRNAs related to stroke risk in patients with AF using bioinformatics analysis.MethodsGSE66724 microarray data, including peripheral blood samples from eight patients with AF and stroke and eight patients with AF without...
09:28
Exploration of the role of serum ghrelin in the diagnosis and treatment of digestive tract malignancies: Journal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveThe incidence of digestive tract malignancies (DTMs) is increasing, early diagnosis is limited, and treatment effects are unsatisfactory. DTMs express ghrelin, which might be involved in tumor formation and development; whether serum ghrelin can provide useful guidance remains unknown.MethodsSera of healthy individuals...
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SAGE Publications Ltd: Journal of International Medical Research: Table of Contents, Usefulness of non-invasive cardiac output monitoring in elderly patients undergoing monopolar transurethral resection of the prostate: a pilot studyJournal of International Medical Research, Volume 48, Issue 5, May 2020. ObjectiveTo assess the impact of irrigating fluid on hemodynamic profiles using real-time non-invasive cardiac output monitoring (NICOM) in elderly patients undergoing monopolar transurethral resection...
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Elevated PCT at ICU discharge predicts poor prognosis in patients with severe traumatic brain injury: a retrospective cohort study: Journal of International Medical Research, Volume 48, Issue 5, May 2020. PurposeDisease severity and inflammatory response status are closely related to a poor prognosis and must be assessed in patients with severe traumatic brain injury (STBI) before intensive care unit (ICU) discharge. Whether elevated serum procalcitonin (PCT) levels can predict a poor prognosis in...
09:27
Distinction between the Lymph Vessel and the Vein on ICG lymphography: Intradermal or Subcutaneous ICG Injection also Enhances the Vein: We read the article reported by Hara et al. (Hara H, et al. Multilymphosome injection indocyanine green lymphography can detect more lymphatic vessels than lymphoscintigraphy in lymphedematous limbs. J Plast Reconstr Aesthet Surg. 2020 Jan 21. [Epub ahead of print]) with an interest, and agree with their conclusive statement that multiple injection indocyanine green...
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Analytical Chemistry,[ASAP] Isothermal Chemical Denaturation: Data Analysis, Error Detection, and Correction by PARAFAC2Analytical ChemistryDOI: 10.1021/acs.analchem.9b05748Analytical ChemistryTue May 05, 2020 07:00[ASAP] Rapid and Sensitive Detection of anti-SARS-CoV-2 IgG, Using Lanthanide-Doped Nanoparticles-Based Lateral Flow ImmunoassayAnalytical ChemistryDOI: 10.1021/acs.analchem.0c00784Analytical ChemistryTue May 05, 2020 07:00[ASAP] Excimer-FRET Cascade in Dual DNA Probes: Open Access to...
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Eplasty,Earlobe Reconstruction With an Anteriorly Based Postauricular Flap.Related ArticlesEarlobe Reconstruction With an Anteriorly Based Postauricular Flap. Eplasty. 2020;20:ic7 Authors: Chang J, Awh C, Riccio CA, Konofaos P PMID: 32362993 [PubMed]Eplasty03:37PIK3CA-Related Overgrowth Syndrome (PROS) and Angiosarcoma: A Case Report.Related ArticlesPIK3CA-Related Overgrowth Syndrome (PROS) and Angiosarcoma: A Case Report. Eplasty. 2020;20:ic6 Authors: Weinstein B, Henderson-Jackson E, Cruse CW,...
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Journal of the American Chemical Society: Latest Articles (ACS Publications), [ASAP] All-Inorganic Halide Perovskites as Potential Thermoelectric Materials: Dynamic Cation off-Centering Induces Ultralow Thermal ConductivityJournal of the American Chemical SocietyDOI: 10.1021/jacs.0c03427Journal of the American Chemical Society: Latest Articles (ACS Publications)Tue May 05, 2020 07:00[ASAP] Too Persistent to Give Up: Aromaticity in Boron Clusters Survives Radical Structural ChangesJournal of the...
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RNA In Advance,RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers [Article]RNA-Puzzles is a collective endeavor dedicated to the advancement and improvement of RNA 3D structure prediction. With agreement from crystallographers, the RNA structures are predicted by various groups before the publication of the crystal structures. We now report the prediction of six RNA sequences: four structures of nucleolytic ribozymes and two of riboswitches. Systematic protocols for...
09:24
Clinical Cancer Research Online First Articles,Association of NOS3 and ANGPT2 gene polymorphisms with survival in patients with hepatocellular carcinoma receiving sorafenib: results of the multicenter prospective INNOVATE studyPurpose: After 10 years of clinical practice and research studies, there are still no validated prognostic or predictive factors of response to sorafenibfor hepatocellular carcinoma (HCC).On the basis of the results of our two retrospective studies, we designed the multicenter...
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Clinical Cancer Research Online First Articles,Chimeric Antigen Receptor-Glypican-3 T-Cell Therapy for Advanced Hepatocellular Carcinoma: Results of Phase 1 TrialsPurpose: Our preclinical studies demonstrated the potential of chimeric antigen receptor (CAR)-glypican-3 (GPC3) T-cell therapy for hepatocellular carcinoma (HCC). We report herein the first published results of CAR-GPC3 T-cell therapy for HCC. Materials and Methods: In two prospective phase 1 studies, adult patients with advanced GPC3+...
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Concurrent definitive immunoradiotherapy for patients with Stage III-IV Head and Neck Cancer and Cisplatin contraindication: Purpose: Although cisplatin plus radiotherapy is a standard treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC), cisplatin contraindication is common. Radiation elicits and promotes tumor-directed immune-stimulation, which may potentiate anti-PD-1 therapy. We provide the first efficacy report of combined pembrolizumab and definitive radiotherapy...
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Latest Results for Maternal and Child Health Journal,Using Supervised Learning Methods to Develop a List of Prescription Medications of Greatest Concern during PregnancyAbstract Introduction Women and healthcare providers lack adequate information on medication safety during pregnancy. While resources describing fetal risk are available, information is provided in multiple locations, often with subjective assessments of available data. We developed a list of medications of greatest concern during...
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European Journal of Neuroscience,Participation of TRPV1 in the activity of the GnRH system in male ratsAbstract GnRH neuron activity is under the influence of multiple stimuli, including those coming from the endocannabinoid and the immune systems. Since it has been previously suggested that some of the main elements controlling the GnRH pulse generator possess the TRPV1 receptor, the aim of the present study was to evaluate the participation of the hypothalamic TRPV1, through its pharmacological...
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Journal of Experimental & Clinical Cancer Research - Latest Articles,Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancersAdapter chimeric antigen receptor (CAR) approaches have emerged has promising strategies to increase clinical safety of CAR T-cell therapy. In the UniCAR system, the safety switch is controlled via a target mo...Journal of Experimental & Clinical Cancer Research - Latest ArticlesTue May 05, 2020 03:00Downregulation of GLYR1...
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Progressively increasing density of the solid center of a ground‐glass nodule in a solitary pulmonary capillary hemangioma: A case report: Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground‐glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiological distinction from peripheral lung cancers...
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Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma:
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Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma: British Journal of Cancer, Published online: 06 May 2020; doi:10.1038/s41416-020-0871-1Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma
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Latest Results for Psychopharmacology,Quantification of observable behaviors induced by typical and atypical kappa-opioid receptor agonists in male rhesus monkeysAbstract Rationale Kappa-opioid receptor (KOR) agonists are antinociceptive but have side effects that limit their therapeutic utility. New KOR agonists have been developed that are fully efficacious at the KOR but may produce fewer or reduced side effects that are typical of KOR agonists. Objectives We determined behavioral profiles for...
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G3: .Genes, Genomes, Genetics Mission - Online First Articles,Inferring Parameters of the Distribution of Fitness Effects of New Mutations When Beneficial Mutations Are Strongly Advantageous and RareCharacterising the distribution of fitness effects (DFE) for new mutations is central in evolutionary genetics. Analysis of molecular data under the McDonald-Kreitman test has suggested that adaptive substitutions make a substantial contribution to between-species divergence. Methods have been proposed...
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Oral and Maxillofacial Surgery,Perils of Intermaxillary Fixation ScrewsIntermaxillary fixation (IMF) screws, typically self-tapping, are easy and quick to use, seemingly safe, are compatible with plating systems, reduce buccal and gingival tissue trauma and are used to assist with open reduction and internal fixation (ORIF) of fractured mandibles.1 However, there is limited literature on complications that may arise with their use.2Oral and Maxillofacial SurgeryTue May 05, 2020 03:00A perspective...
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Laser,Nonlinear optical microscopy is a novel tool for the analysis of cutaneous alterations in pseudoxanthoma elasticumAbstract Pseudoxanthoma elasticum (PXE, OMIM 264800) is a rare autosomal recessive disorder with ectopic mineralization and fragmentation of elastin fibers. It is caused by mutations of the ABCC6 gene that leads to decreased serum levels of inorganic pyrophosphate (PPi) anti-mineralization factor. The occurrence of severe complications among PXE patients highlights the importance...
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Oncogenesis - Loss of <i>HAT1</i> expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1ROncogenesis, Published online: 05 May 2020; doi:10.1038/s41389-020-0228-xLoss of HAT1 expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1ROncogenesis - nature.com science feedsTue May 05, 2020 03:00Loss of <i>HAT1</i> expression confers BRAFV600E inhibitor resistance to melanoma cells...
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Journal of Internal Medicine,Copper deficiency, heart disease and homocysteine thiolactoneJournal of Internal MedicineMon May 04, 2020 16:22Ethnic differences in adiposity and diabetes risk – insights from genetic studiesAbstract Type 2 diabetes is more common in non‐Europeans and starts at a younger age and at lower BMI cut‐offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of adiposity and body...
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Toxocara infection: seroprevalence and associated risk factors among primary school children in central China: Authors: Shuai Wang, Haoran Li, Zhijun Yao, Pengju Li, Dong Wang, Haizhu Zhang, Qing Xie, Zhenchao Zhang and Xiangrui Li.<br />Parasite Vol. 27 , page 30<br />Published online: 05/05/2020<br /> Keywords: Toxocara ; Primary school children ; Seroprevalence ; Risk factors ; Central China.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/rtk9evfetec"...
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Tumour biomarkers: association with heart failure outcomes: AbstractBackgroundThere is increasing recognition that heart failure (HF) and cancer are conditions with a number of shared characteristics.ObjectivesTo explore the association between tumour biomarkers and HF outcomes.MethodsIn 2,079 patients of BIOSTAT‐CHF cohort, we measured six established tumour biomarkers: CA125, CA15‐3, CA19‐9, CEA, CYFRA 21‐1 and AFP.ResultsDuring a median follow‐up of 21 months, 555 (27%) patients reached the primary...
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Latest Results for Folia Microbiologica,Corn stover induces extracellular laccase activity in Didymosphaeria sp. (syn. = Paraconiothyrium sp.) and exhibits increased in vitro ruminal digestibility when treated with this fungal speciesAbstract Fungi can improve stover digestibility due to their ability to secrete oxidative enzymes that depolymerize lignin, allowing the rumen microorganisms to access the polysaccharides of the plant cell wall. Some ascomycetes have shown good delignification capability;...
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Hormon- und Stoffwechselforschung,Liraglutide Ameliorates Lipotoxicity-Induced Oxidative Stress by Activating the NRF2 Pathway in HepG2 CellsHorm Metab ResDOI: 10.1055/a-1157-0166Although glucagon-like peptide-1 (GLP-1) analogue has been reported to suppress oxidative stress in non-alcoholic fatty liver disease (NAFLD), an effective therapeutic agent for NAFLD is currently unavailable. Therefore, in this study, we aimed to investigate the protective effects of the GLP-1 analogue liraglutide against...
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Cancer survivors' experiences with financial toxicity: A systematic review and meta‐synthesis of qualitative studies: AbstractObjectiveThe aim of this study was to synthesize qualitative research evidence on cancer survivors' experiences with financial toxicity (FT).MethodsWe carried out a systematic review of qualitative studies using a meta‐aggregation approach. Papers published prior to 31 August 2019, were collected from electronic databases, including PubMed/MEDLINE, MEDLINE (Ovid), EMBASE (Ovid),...
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Stopping CSF leaks at external ventricular drain exit sites: a technical note: AbstractPurposeCerebrospinal fluid (CSF) leak is a major risk factor for external ventricular drain infection. Here, we present a surgical technique to reduce the possibility of CSF leak at the external ventricular drain (EVD) exit site in high-risk patients.MethodsVertical mattress sutures are placed circumferentially around the EVD catheter tract as it passes under the skin, so to close off the tract along which CSF...
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Proteomics of pediatric ependymomas: a review: AbstractEpendymomas, affecting both children and adults, are neuroepithelial tumors occurring throughout all compartments of the central nervous system. Pediatric ependymomas arise almost exclusively intracranially and are associated with a poor 10-year overall survival of around 60%. During the last years, the application of multi-omics technologies on the study and understanding of neuro-cancer diseases has become a standard; in this regard, application...
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Outcomes and prognostic factors of pediatric patients with a Glasgow Coma Score of 3 after blunt head trauma: AbstractPurposeThis study aims to assess outcomes of pediatric patients with blunt traumatic brain injury (TBI) with a presenting Glasgow Coma Score (GCS) of 3.MethodsAfter local institutional review board approval, we identified patients ages 0 to15 years with blunt TBI and a reported GCS of 3 between 2007 and 2017 from a pediatric level 1 trauma center prospective registry. Exclusion criteria...
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Water, Vol. 12, Pages 1308: Assessing Impact of Climate Change on Hydrology of Melka Kuntrie Subbasin, Ethiopia With Ar4 and Ar5 ProjectionsWater, Vol. 12, Pages 1308: Assessing Impact of Climate Change on Hydrology of Melka Kuntrie Subbasin, Ethiopia With Ar4 and Ar5 Projections Water doi: 10.3390/w12051308 Authors: Yitea Seneshaw Getahun Ming-Hsu Li and Pei-Yuan Chen Assessing future challenges in water resources management is crucial to the Melka Kuntrie (MK) subbasin suffering water shortage....
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Toxins, Vol. 12, Pages 297: Potential Roles and Functions of Listerial Virulence Factors during Brain EntryToxins, Vol. 12, Pages 297: Potential Roles and Functions of Listerial Virulence Factors during Brain Entry Toxins doi: 10.3390/toxins12050297 Authors: Franjo Banović Horst Schroten Christian Schwerk Although it rarely induces disease in humans, Listeria monocytogenes (Lm) is important due to the frequency of serious pathological conditions—such as sepsis and meningitis—it causes in those few...
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JCM, Vol. 9, Pages 1357: Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States: JCM, Vol. 9, Pages 1357: Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United StatesJournal of Clinical Medicine doi: 10.3390/jcm9051357Authors: Tarun Bathini Charat Thongprayoon Api Chewcharat Tananchai Petnak Wisit Cheungpasitporn Boonphiphop Boonpheng Narut Prasitlumkum Ronpichai Chokesuwattanaskul Saraschandra Vallabhajosyula Wisit Kaewput...
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Vaccines, Vol. 8, Pages 209: Arthritogenic Alphavirus Vaccines: Serogrouping Versus Cross-Protection in Mouse Models: Vaccines, Vol. 8, Pages 209: Arthritogenic Alphavirus Vaccines: Serogrouping Versus Cross-Protection in Mouse ModelsVaccines doi: 10.3390/vaccines8020209Authors: Wilson Nguyen Eri Nakayama Kexin Yan Bing Tang Thuy T. Le Liang Liu Tamara H. Cooper John D. Hayball Helen M. Faddy David Warrilow Richard J. N. Allcock Jody Hobson-Peters Roy A. Hall Daniel J....
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Viruses, Vol. 12, Pages 511: An RNA-Directed Gene Editing Strategy for Attenuating the Infectious Potential of Feline Immunodeficiency Virus-Infected Cells: A Proof of ConceptViruses, Vol. 12, Pages 511: An RNA-Directed Gene Editing Strategy for Attenuating the Infectious Potential of Feline Immunodeficiency Virus-Infected Cells: A Proof of Concept Viruses doi: 10.3390/v12050511 Authors: Brian G. Murphy Tatiana Wolf Helena Vogel Diego Castillo Kevin Woolard Modern antiretroviral therapy for immunodeficiency...
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Resources, Vol. 9, Pages 55: Importance of Sustainable Mineral Resource Management in Implementing the Circular Economy (CE) Model and the European Green Deal Strategy: Resources, Vol. 9, Pages 55: Importance of Sustainable Mineral Resource Management in Implementing the Circular Economy (CE) Model and the European Green Deal StrategyResources doi: 10.3390/resources9050055Authors: Marzena Smol Paulina Marcinek Joanna Duda Dominika Szołdrowska The European Green Deal is the new strategy for...
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Toxins, Vol. 12, Pages 296: Minimizing Ochratoxin A Contamination through the Use of Actinobacteria and Their Active Molecules: Toxins, Vol. 12, Pages 296: Minimizing Ochratoxin A Contamination through the Use of Actinobacteria and Their Active MoleculesToxins doi: 10.3390/toxins12050296Authors: Ixchel Campos-Avelar Alexandre Colas de la Noue Noel Durand Blandine Fay Véronique Martinez Angélique Fontana Caroline Strub Sabine Schorr-Galindo Ochratoxin A (OTA) is a secondary metabolite...
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Religions, Vol. 11, Pages 228: The Legacies of Bindy Johal: The Contemporary Folk Devil or Sympathetic Hero: Religions, Vol. 11, Pages 228: The Legacies of Bindy Johal: The Contemporary Folk Devil or Sympathetic HeroReligions doi: 10.3390/rel11050228Authors: Manjit Pabla A folk devil has the ability to elicit a community's fear over crime. Notorious late gangster, Bindy Johal, occupies this position as his legacy stirs the social anxieties over gang violence by some in the Punjabi-Sikh community...
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Plants, Vol. 9, Pages 590: MCA1 and MCA2 Are Involved in the Response to Hypergravity in Arabidopsis HypocotylsPlants, Vol. 9, Pages 590: MCA1 and MCA2 Are Involved in the Response to Hypergravity in Arabidopsis Hypocotyls Plants doi: 10.3390/plants9050590 Authors: Hattori Otomi Nakajima Soga Wakabayashi Iida Hoson Plants respond to and resist gravitational acceleration, but the mechanism of signal perception in the response is unknown. We studied the role of MCA (mid1-complementing activity) proteins...
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Safety, Vol. 6, Pages 22: A Model to Predict Children's Reaction Time at Signalized Intersections: Safety, Vol. 6, Pages 22: A Model to Predict Children's Reaction Time at Signalized IntersectionsSafety doi: 10.3390/safety6020022Authors: Irena Ištoka Otković Traffic accident statistics in urban areas, both locally in Croatia and at the European level, identify children as a group of vulnerable road users. The analysis of the parameters that influence the interaction of child pedestrians and other...
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Nutrients, Vol. 12, Pages 1316: Beyond Body Weight-Loss: Dietary Strategies Targeting Intrahepatic Fat in NAFLDNutrients, Vol. 12, Pages 1316: Beyond Body Weight-Loss: Dietary Strategies Targeting Intrahepatic Fat in NAFLD Nutrients doi: 10.3390/nu12051316 Authors: Nicolai Worm Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease in industrialized countries. It is regarded as the hepatic manifestation of the metabolic syndrome (MetS) resulting from insulin resistance....
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Pharmaceutics, Vol. 12, Pages 423: Gel Formulation of Nabumetone and a Newly Synthesized Analog: Microemulsion as a Photoprotective Topical Delivery System: Pharmaceutics, Vol. 12, Pages 423: Gel Formulation of Nabumetone and a Newly Synthesized Analog: Microemulsion as a Photoprotective Topical Delivery SystemPharmaceutics doi: 10.3390/pharmaceutics12050423Authors: Fedora Grande Gaetano Ragno Rita Muzzalupo Maria Antonietta Occhiuzzi Elisabetta Mazzotta Michele De Luca Antonio Garofalo...
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Pathogens, Vol. 9, Pages 350: Silver Nanoparticles as a Novel Potential Preventive Agent against Acanthamoeba KeratitisPathogens, Vol. 9, Pages 350: Silver Nanoparticles as a Novel Potential Preventive Agent against Acanthamoeba Keratitis Pathogens doi: 10.3390/pathogens9050350 Authors: Hendiger Padzik Sifaoui Reyes-Batlle López-Arencibia Rizo-Liendo Bethencourt-Estrella Nicolás-Hernández Chiboub Rodríguez-Expósito Grodzik Pietruczuk-Padzik Stępień Olędzka Chomicz Piñero Lorenzo-Morales Free living,...
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Nanomaterials, Vol. 10, Pages 887: Strategies to Improve Nanofibrous Scaffolds for Vascular Tissue EngineeringNanomaterials, Vol. 10, Pages 887: Strategies to Improve Nanofibrous Scaffolds for Vascular Tissue Engineering Nanomaterials doi: 10.3390/nano10050887 Authors: Tianyu Yao Matthew B. Baker Lorenzo Moroni The biofabrication of biomimetic scaffolds for tissue engineering applications is a field in continuous expansion. Of particular interest, nanofibrous scaffolds can mimic the mechanical and...
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Molecules, Vol. 25, Pages 2166: Subcritical Water Extraction of Valuable Metals from Spent Lithium-Ion BatteriesMolecules, Vol. 25, Pages 2166: Subcritical Water Extraction of Valuable Metals from Spent Lithium-Ion Batteries Molecules doi: 10.3390/molecules25092166 Authors: Jenni Lie Stefani Tanda Jhy-Chern Liu The leaching of valuable metals (Co, Li, and Mn) from spent lithium-ion batteries (LIBs) was studied using subcritical water extraction (SWE). Two types of leaching agents, hydrochloric acid...
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J. Imaging, Vol. 6, Pages 29: Unsupervised Clustering of Hyperspectral Paper Data Using t-SNE: J. Imaging, Vol. 6, Pages 29: Unsupervised Clustering of Hyperspectral Paper Data Using t-SNEJournal of Imaging doi: 10.3390/jimaging6050029Authors: Binu Melit Devassy Sony George Peter Nussbaum For a suspected forgery that involves the falsification of a document or its contents, the investigator will primarily analyze the document's paper and ink in order to establish the authenticity of the subject...
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Microorganisms, Vol. 8, Pages 670: The Role of Bacterial Membrane Vesicles in the Dissemination of Antibiotic Resistance and as Promising Carriers for Therapeutic Agent DeliveryMicroorganisms, Vol. 8, Pages 670: The Role of Bacterial Membrane Vesicles in the Dissemination of Antibiotic Resistance and as Promising Carriers for Therapeutic Agent Delivery Microorganisms doi: 10.3390/microorganisms8050670 Authors: Md Jalal Uddin Jirapat Dawan Gibeom Jeon Tao Yu Xinlong He Juhee Ahn The rapid emergence...
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Medicina, Vol. 56, Pages 219: Influence of a Foot Insole for a Down Syndrome Patient with a Flat Foot: A Case StudyMedicina, Vol. 56, Pages 219: Influence of a Foot Insole for a Down Syndrome Patient with a Flat Foot: A Case Study Medicina doi: 10.3390/medicina56050219 Authors: Yusuke Endo Yoshihide Kanai Arito Yozu Yasuto Kobayashi Takashi Fukaya Hirotaka Mutsuzaki Background and Objectives: Patients with Down syndrome have many orthopedic problems including flat foot. Insertion of an insole for...
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JFB, Vol. 11, Pages 29: Synthetic Bone Substitutes and Mechanical Devices for the Augmentation of Osteoporotic Proximal Humeral Fractures: A Systematic Review of Clinical Studies: JFB, Vol. 11, Pages 29: Synthetic Bone Substitutes and Mechanical Devices for the Augmentation of Osteoporotic Proximal Humeral Fractures: A Systematic Review of Clinical StudiesJournal of Functional Biomaterials doi: 10.3390/jfb11020029Authors: Giuseppe Marongiu Marco Verona Gaia Cardoni Antonio Capone Background:...
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Journal of Clinical Medicine,JCM, Vol. 9, Pages 1356: Anti-Aminoacyl Transfer-RNA-Synthetases (Anti-tRNA) Autoantibodies Associated with Interstitial Lung Disease: Pulmonary Disease Progression has a Persistent Elevation of the Th17 Cytokine ProfileJCM, Vol. 9, Pages 1356: Anti-Aminoacyl Transfer-RNA-Synthetases (Anti-tRNA) Autoantibodies Associated with Interstitial Lung Disease: Pulmonary Disease Progression has a Persistent Elevation of the Th17 Cytokine Profile Journal of Clinical Medicine doi:...
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International Journal of Molecular Sciences,IJMS, Vol. 21, Pages 3276: Designer Biopolymers: Self-Assembling Proteins and Nucleic AcidsIJMS, Vol. 21, Pages 3276: Designer Biopolymers: Self-Assembling Proteins and Nucleic Acids International Journal of Molecular Sciences doi: 10.3390/ijms21093276 Authors: Ayae Sugawara-Narutaki Yukiko Kamiya Nature has evolved sequence-controlled polymers such as DNA and proteins over its long history [...]International Journal of Molecular Sciences03:00IJMS, Vol....
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HealthcareHealthcare, Vol. 8, Pages 124: Unmet Dental Care Needs among Korean National Health Insurance Beneficiaries Based on Income Inequalities: Results from Five Waves of a Population-Based Panel StudyHealthcare, Vol. 8, Pages 124: Unmet Dental Care Needs among Korean National Health Insurance Beneficiaries Based on Income Inequalities: Results from Five Waves of a Population-Based Panel Study Healthcare doi: 10.3390/healthcare8020124 Authors: Minsung Sohn Xianhua Che Hee-Jung Park This study...
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Foods, Vol. 9, Pages 588: The Effect of Whey on Performance, Gut Health and Bone Morphology Parameters in Broiler ChicksFoods, Vol. 9, Pages 588: The Effect of Whey on Performance, Gut Health and Bone Morphology Parameters in Broiler Chicks Foods doi: 10.3390/foods9050588 Authors: Vasileios Tsiouris Michael G. Kontominas Giorgos Filioussis Sofia Chalvatzi Ilias Giannenas Georgios Papadopoulos Konstantinos Koutoulis Paschalis Fortomaris Ioanna Georgopoulou Whey is a highly nutritious byproduct of...
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Diversity, Vol. 12, Pages 179: Life History Divergence in Livebearing Fishes in Response to Predation: Is There a Microevolution to Macroevolution Barrier?Diversity, Vol. 12, Pages 179: Life History Divergence in Livebearing Fishes in Response to Predation: Is There a Microevolution to Macroevolution Barrier? Diversity doi: 10.3390/d12050179 Authors: Mark C. Belk Spencer J. Ingley Jerald B. Johnson A central problem in evolutionary biology is to determine whether adaptive phenotypic variation within...
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Cells, Vol. 9, Pages 1138: Regulation of TMEM16A by CK2 and Its Role in Cellular ProliferationCells, Vol. 9, Pages 1138: Regulation of TMEM16A by CK2 and Its Role in Cellular Proliferation Cells doi: 10.3390/cells9051138 Authors: Madalena C. Pinto Rainer Schreiber Joana Lerias Jiraporn Ousingsawat Aires Duarte Margarida Amaral Karl Kunzelmann Casein kinase 2 (CK2) is a highly ubiquitous and conserved serine/threonine kinase that forms a tetramer consisting of a catalytic subunit (CK2α) and a regulatory...
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Diagnostics, Vol. 10, Pages 279: CCNE1 Amplification as a Predictive Biomarker of Chemotherapy Resistance in Epithelial Ovarian Cancer: Diagnostics, Vol. 10, Pages 279: CCNE1 Amplification as a Predictive Biomarker of Chemotherapy Resistance in Epithelial Ovarian CancerDiagnostics doi: 10.3390/diagnostics10050279Authors: Justin W. Gorski Frederick R. Ueland Jill M. Kolesar Ovarian cancer is the most-deadly gynecologic malignancy, with greater than 14,000 women expected to succumb to the disease...
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Diagnostics, Vol. 10, Pages 280: Loss of Integrase Interactor 1 (INI1) Expression in a Subset of Differentiated Thyroid Cancer: Diagnostics, Vol. 10, Pages 280: Loss of Integrase Interactor 1 (INI1) Expression in a Subset of Differentiated Thyroid CancerDiagnostics doi: 10.3390/diagnostics10050280Authors: Kung-Chen Ho Jie-Jen Lee Chi-Hsin Lin Ching-Hsiang Leung Shih-Ping Cheng Alterations in the switching defective/sucrose non-fermenting (SWI/SNF) chromatin-remodeling complex are enriched...
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Cells, Vol. 9, Pages 1135: Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal Melanomas: Cells, Vol. 9, Pages 1135: Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal MelanomasCells doi: 10.3390/cells9051135Authors: Piotr Donizy Cheng-Lin Wu Jason Mull Masakazu Fujimoto Agata Chłopik Yan Peng Sara C. Shalin M. Angelica Selim Susana Puig Maria-Teresa Fernandez-Figueras Christopher R. Shea Wojciech Biernat...
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Cancers, Vol. 12, Pages 1166: Multicenter Evaluation of Independent High-Throughput and RT-qPCR Technologies for the Development of Analytical Workflows for Circulating miRNA AnalysisCancers, Vol. 12, Pages 1166: Multicenter Evaluation of Independent High-Throughput and RT-qPCR Technologies for the Development of Analytical Workflows for Circulating miRNA Analysis Cancers doi: 10.3390/cancers12051166 Authors: Anna Babayan Martin H. D. Neumann Andrei Herdean Jonathan M. Shaffer Melanie Janning Franca...
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Brain Sciences, Vol. 10, Pages 279: Attentional Flexibility Predicts A-Not-B Task Performance in 14-Month-Old-Infants: A Head-Mounted Eye Tracking Study: Brain Sciences, Vol. 10, Pages 279: Attentional Flexibility Predicts A-Not-B Task Performance in 14-Month-Old-Infants: A Head-Mounted Eye Tracking StudyBrain Sciences doi: 10.3390/brainsci10050279Authors: Hanna Mulder Carolien A. Van Houdt Ineke J. M. Van der Ham Stefan Van der Stigchel Ora Oudgenoeg-Paz Early individual differences in...
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Biomolecules, Vol. 10, Pages 718: Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom PhosphodiesteraseBiomolecules, Vol. 10, Pages 718: Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase Biomolecules doi: 10.3390/biom10050718 Authors: Kaniowski Kulik Ebenryter-Olbińska Wielgus Leśnikowski Nawrot Antisense oligonucleotides conjugated with boron clusters...
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Biosensors, Vol. 10, Pages 48: Smell – Adding a New Dimension to Urinalysis: Biosensors, Vol. 10, Pages 48: Smell – Adding a New Dimension to UrinalysisBiosensors doi: 10.3390/bios10050048Authors: Visser Berkhout Singh Vermeulen Ashtiani Boer Wijk Meij Bökenkamp Background: Urinary tract infections (UTI) are among the most common infections in children. The primary tool to detect UTI is dipstick urinalysis; however, this has limited sensitivity and specificity. Therefore,...
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Biomedicines, Vol. 8, Pages 110: Nobiletin in Cancer Therapy: How This Plant Derived-Natural Compound Targets Various Oncogene and Onco-Suppressor Pathways: Biomedicines, Vol. 8, Pages 110: Nobiletin in Cancer Therapy: How This Plant Derived-Natural Compound Targets Various Oncogene and Onco-Suppressor PathwaysBiomedicines doi: 10.3390/biomedicines8050110Authors: Ashrafizadeh Zarrabi Saberifar Hashemi Hushmandi Hashemi Moghadam Mohammadinejad Najafi Garg Cancer therapy...
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Bioengineering, Vol. 7, Pages 42: Ex-Vivo Stimulation of Adipose Stem Cells by Growth Factors and Fibrin-Hydrogel Assisted Delivery Strategies for Treating Nerve Gap-Injuries: Bioengineering, Vol. 7, Pages 42: Ex-Vivo Stimulation of Adipose Stem Cells by Growth Factors and Fibrin-Hydrogel Assisted Delivery Strategies for Treating Nerve Gap-InjuriesBioengineering doi: 10.3390/bioengineering7020042Authors: Prautsch Degrugillier Schaefer Guzman Kalbermatten Madduri Peripheral nerve...
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Atmosphere, Vol. 11, Pages 467: Deaths Attributable to Air Pollution in Nordic Countries: Disparities in the EstimatesAtmosphere, Vol. 11, Pages 467: Deaths Attributable to Air Pollution in Nordic Countries: Disparities in the Estimates Atmosphere doi: 10.3390/atmos11050467 Authors: Heli Lehtomäki Camilla Geels Jørgen Brandt Shilpa Rao Katarina Yaramenka Stefan Åström Mikael Skou Andersen Lise M. Frohn Ulas Im Otto Hänninen Particulate matter air pollution is widely considered as the leading environmental...
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Antioxidants, Vol. 9, Pages 386: Bioavailability of Coenzyme Q10: An Overview of the Absorption Process and Subsequent MetabolismAntioxidants, Vol. 9, Pages 386: Bioavailability of Coenzyme Q10: An Overview of the Absorption Process and Subsequent Metabolism Antioxidants doi: 10.3390/antiox9050386 Authors: Mantle Dybring A lack of understanding of the processes determining the absorption and subsequent metabolism of coenzyme Q10 (CoQ10) has resulted in some manufacturers' making incorrect claims...
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Antibiotics, Vol. 9, Pages 232: Bacteriophage Therapy for Critical Infections Related to Cardiothoracic SurgeryAntibiotics, Vol. 9, Pages 232: Bacteriophage Therapy for Critical Infections Related to Cardiothoracic Surgery Antibiotics doi: 10.3390/antibiotics9050232 Authors: Evgenii Rubalskii Stefan Ruemke Christina Salmoukas Erin C. Boyle Gregor Warnecke Igor Tudorache Malakh Shrestha Jan D. Schmitto Andreas Martens Sebastian V. Rojas Stefan Ziesing Svetlana Bochkareva Christian Kuehn Axel Haverich...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,