PeerJ Computer ScienceTall Pinus luzmariae trees with genes from P. herreraeContext Pinus herrerae and P. luzmariae are endemic to western Mexico, where they cover an area of more than 1 million hectares. Pinus herrerae is also cultivated in field trials in South Africa and South America, because of its considerable economic importance as a source of timber and resin. Seed quality, afforestation success and desirable traits may all be influenced by the presence of hybrid trees in seed stands. Aims...
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Head and NeckImpact of Time to Diagnosis and Treatment in Head and Neck Cancer: A Systematic Review.Related ArticlesImpact of Time to Diagnosis and Treatment in Head and Neck Cancer: A Systematic Review. Otolaryngol Head Neck Surg. 2020 Feb 25;:194599820906387 Authors: Schutte HW, Heutink F, Wellenstein DJ, van den Broek GB, van den Hoogen FJA, Marres HAM, van Herpen CML, Kaanders JHAM, Merkx TMAW, Takes RP Abstract OBJECTIVE: An increased interval between symptomatic disease and treatment may negatively...
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Head and NeckClinical Profiles of DFNA11 at Diverse Stages of Development and Aging in a Large Family Identified by Linkage Analysis.Related ArticlesClinical Profiles of DFNA11 at Diverse Stages of Development and Aging in a Large Family Identified by Linkage Analysis. Otol Neurotol. 2020 Feb 24;: Authors: Yamamoto N, Mutai H, Namba K, Goto F, Ogawa K, Matsunaga T Abstract HYPOTHESIS: The phenotype of DFNA11 consists of specific features at diverse developmental and age stages. BACKGROUND: Only...
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OncologyPrimary lymph node sites in Hodgkin lymphoma and the risk of second primary cancers: a population-based study.Related ArticlesPrimary lymph node sites in Hodgkin lymphoma and the risk of second primary cancers: a population-based study. Future Oncol. 2020 Feb 25;: Authors: Ebied A, Yousif M, Nam NH, Elhamamsy AR, Hassan OG, Mostafa EM, Nguyen GJ, Hirayama K, Huy NT Abstract Aim: Little is known about the association between specific primary lymph node (LN) sites and the risk of developing...
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cortical auditoryContext-dependent signaling of coincident auditory and visual events in primary visual cortex.Related ArticlesContext-dependent signaling of coincident auditory and visual events in primary visual cortex. Elife. 2019 05 23;8: Authors: Deneux T, Harrell ER, Kempf A, Ceballo S, Filipchuk A, Bathellier B Abstract Detecting rapid, coincident changes across sensory modalities is essential for recognition of sudden threats or events. Using two-photon calcium imaging in identified cell...
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pubmed: sleep apneaCan drug-induced sleep endoscopy improve the success rates of tongue base surgery?Related ArticlesCan drug-induced sleep endoscopy improve the success rates of tongue base surgery? J Otolaryngol Head Neck Surg. 2020 Feb 24;49(1):8 Authors: Ha JG, Lee Y, Nam JS, Park JJ, Yoon JH, Kim CH, Cho HJ Abstract BACKGROUND: The purpose of this study was to determine the therapeutic value of drug-induced sleep endoscopy (DISE) by comparing the outcomes of tongue base surgery based on Muller's...
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Latest Results for Sports MedicineMeasuring Well-Being in Sport Performers: Where are We Now and How do we Progress?Abstract The importance of optimal well-being and mental health in elite athletes has received increasing attention and debate in both the academic and public discourse. Despite the number of challenges and risk factors for mental health and well-being recognised within the performance lifestyle of elite athletes, the evidence base for intervention is limited by a number of methodological...
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European Journal of Surgical Oncology (EJSO)Clinical outcome of post-chemotherapy retroperitoneal lymph node dissection in metastatic nonseminomatous germ cell tumour: A systematic reviewPublication date: Available online 26 February 2020Source: European Journal of Surgical OncologyAuthor(s): Rianne Haarsma, Joost M. Blok, Kim van Putten, Richard P. MeijerEuropean Journal of Surgical Oncology (EJSO)Wed Feb 26, 2020 15:05Psychosocial well-being at time of diagnosis of breast cancer affects the decision...
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Pediatric OtorhinolaryngologyObstructive sleep apnea in children with Down syndrome - Prevalence and evaluation of surgical treatmentPublication date: Available online 26 February 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Pia Nerfeldt, Amalia SundelinPediatric OtorhinolaryngologyWed Feb 26, 2020 16:34Application of mesenchymal stem cell for tympanic membrane regeneration by tissue engineering approachPublication date: Available online 25 February 2020Source: International...
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Indian Journal of Pathology and Microbiology : 2015 - 58(2)Primary Ewing sarcoma of the kidney in an adult and a child: Solving a diagnostic challengeDiya Das, Chhanda Datta, Uttara Chatterjee, Dilip Kumar PalIndian Journal of Pathology and Microbiology 2020 63(5):61-63Indian Journal of Pathology and Microbiology : 2015 - 58(2)Wed Feb 26, 2020 00:00Secretory carcinoma of breast: A diagnostic dilemmaAnju Shukla, Farah Arshad, Iqbal NaseemIndian Journal of Pathology and Microbiology 2020 63(5):143-145Indian...
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The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical PracticeEscaping Pandora's Box — Another Novel CoronavirusThe 1918 influenza pandemic was the deadliest event in human history (50 million or more deaths, equivalent in proportion to 200 million in today's global population). For more than a century, it has stood as a benchmark against which all other pandemics and disease emergences have been measured.…The New England Journal of Medicine: Search Results in...
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PsychophysiologyCan arterial elasticity be estimated from heart rate variability response to paced 0.066 Hz sighing?Abstract Arterial elasticity is an important indicator of risk for cardiovascular disease (CVD). It is influenced by both gradual vessel wall damage due to aging and disease and vascular tone that responds, at the moment, to system loading. Measuring changes in arterial elasticity are critical to early detection of CVD but can be time and resource intensive. This study proposes and...
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The University of Chicago Press on behalf of Wenner-Gren Foundation for Anthropological Research: Current AnthropologySex, Prestige, and Booming Death—or Eating Bread: Natufian Low-Level Food Production in Southwest Asia (15,000–11,500 Cal BP): A Comment on Rosenberg and Nadel 2014Current Anthropology, Volume 61, Issue 1, Page 124-128, February 2020.The University of Chicago Press on behalf of Wenner-Gren Foundation for Anthropological Research: Current AnthropologyWed Feb 26, 2020 12:30The Function...
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Ear and Hearing - Current IssueVocal Turn-Taking Between Mothers and Their Children With Cochlear ImplantsObjectives: The primary objective of the study was to examine the occurrence and temporal structure of vocal turn-taking during spontaneous interactions between mothers and their children with cochlear implants (CI) over the first year after cochlear implantation as compared with interactions between mothers and children with normal hearing (NH). Design: Mothers' unstructured play sessions with...
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Plastic and Reconstructive Surgery - Current IssuePatient-Reported Outcomes following Surgical Treatment of Symptomatic Digital NeuromasBackground: Many surgical techniques are used to treat symptomatic neuroma, but options are limited for digital neuromas because of a paucity of soft-tissue coverage and/or the absence of the terminal nerve end. The authors assessed factors that influence patient-reported outcomes after surgery for symptomatic digital neuroma. Methods: The authors retrospectively...
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Plastic and Reconstructive Surgery - Current IssueString Fat/Dermis Graft for Correction of Wrinkles and ScarsNo abstract availablePlastic and Reconstructive Surgery - Current Issue04:16Surgical Correction of Breast Animation Deformity with Implant Pocket Conversion to a Prepectoral PlaneBackground: Animation deformity is an undesirable outcome of subpectoral breast reconstruction that results in abnormal breast contraction with activity, breast pain, and increased implant visibility. Surgical correction...
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Annals of Indian Academy of Neurology : 2015 - 18(2)Levodopa-responsive chorea: A reviewMark Farrenburg, Harsh V GuptaAnnals of Indian Academy of Neurology 2020 23(2):211-214 Background: Chorea is one of the disabling movement disorders, and the number of drugs which can treat this disorder effectively is limited. Tetrabenazine and deutetrabenazine are the two drugs approved by the US-FDA for the treatment of chorea associated with HD. Levodopa can improve chorea in some disorders, and this review...
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Journal of neuro-ophthalmologyEffect of Positioning on Intracranial PressureNo abstract availableJournal of neuro-ophthalmology06:20Treatment of Ptosis Using Brimonidine Tartrate for Anterior Laminectomy-Induced Horner SyndromeNo abstract availableJournal of neuro-ophthalmology06:20American Academy of Ophthalmology and Neuro-Ophthalmology Subspecialty Day 2019 SummaryNo abstract availableJournal of neuro-ophthalmology06:20Oculopalatal Tremor With Dissociated Pendular Nystagmus in Bilateral Inferior...
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Indian Journal of Cancer : 2014 - 51(1)Peer-review and post-publication discourse: The challengesRaj Kumar Shrimali, Yakhub Mohammed KhanIndian Journal of Cancer 2020 57(1):108-109Indian Journal of Cancer : 2014 - 51(1)Wed Feb 26, 2020 00:00Eribulin monotherapy in heavily pretreated metastatic breast cancer patients in real lifeMurat Sari, Pınar SaipIndian Journal of Cancer 2020 57(1):55-61 Background and Aim: Our retrospective, single-center study aimed at evaluating the efficacy and safety of...
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AudiologyAcoustics Team for the International Space Station Wins 2020 Safe-in-Sound AwardThe National Institute for Occupational Safety and Health (NIOSH) partnered with the National Hearing Conservation Association (NHCA) to create the Safe-in-Sound Excellence in Hearing Loss Prevention Awards™, to recognize organizations that document measurable achievements in hearing loss prevention, and to obtain information on their real-world successes. This year's award ceremony takes place at the Annual...
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LINC00662 triggers malignant progression of chordoma by the activation of RNF144B via targeting miR-16-5p.Related ArticlesLINC00662 triggers malignant progression of chordoma by the activation of RNF144B via targeting miR-16-5p. Eur Rev Med Pharmacol Sci. 2020 Feb;24(3):1007-1022 Authors: Wang CB, Wang Y, Wang JJ, Guo XL Abstract OBJECTIVE: Chordoma is a rare malignant tumor difficult to diagnose and treat. Long non-coding RNAs acting as novel biomarkers are frequently reported in numerous cancers....
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ReligionsReligions, Vol. 11, Pages 105: Multifaith Third Spaces: Digital Activism, Netpeace, and the Australian Religious Response to Climate ChangeReligions, Vol. 11, Pages 105: Multifaith Third Spaces: Digital Activism, Netpeace, and the Australian Religious Response to Climate Change Religions doi: 10.3390/rel11030105 Authors: Geraldine Smith Anna Halafoff Multifaith spaces typically imply sites where people of diverse faith traditions gather to participate in shared activities or practices,...
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MoleculesMolecules, Vol. 25, Pages 1045: Application of Halogen Bonding to Organocatalysis: A Theoretical PerspectiveMolecules, Vol. 25, Pages 1045: Application of Halogen Bonding to Organocatalysis: A Theoretical Perspective Molecules doi: 10.3390/molecules25051045 Authors: Hui Yang Ming Wah Wong The strong, specific, and directional halogen bond (XB) is an ideal supramolecular synthon in crystal engineering, as well as rational catalyst and drug design. These attributes attracted strong growing...
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International Journal of Molecular SciencesIJMS, Vol. 21, Pages 1582: Secreted Factors and EV-miRNAs Orchestrate the Healing Capacity of Adipose Mesenchymal Stem Cells for the Treatment of Knee OsteoarthritisIJMS, Vol. 21, Pages 1582: Secreted Factors and EV-miRNAs Orchestrate the Healing Capacity of Adipose Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis International Journal of Molecular Sciences doi: 10.3390/ijms21051582 Authors: Ragni Perucca Orfei De Luca Colombini Viganò de...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 1494: Hyperlipidemia and Statins Use for the Risk of New Diagnosed Sarcopenia in Patients with Chronic Kidney: A Population-Based StudyIJERPH, Vol. 17, Pages 1494: Hyperlipidemia and Statins Use for the Risk of New Diagnosed Sarcopenia in Patients with Chronic Kidney: A Population-Based Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17051494 Authors: Lin Chiu Chang...
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CellsCells, Vol. 9, Pages 540: Translational Regulations in Response to Endoplasmic Reticulum Stress in CancersCells, Vol. 9, Pages 540: Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers Cells doi: 10.3390/cells9030540 Authors: Jaud Philippe Di Bella Tang Pyronnet Laurell Mazzolini Rouault-Pierre Touriol Abstract: During carcinogenesis, almost all the biological processes are modified in one way or another. Among these biological processes affected, anomalies in protein...
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AntibioticsAntibiotics, Vol. 9, Pages 99: Synthesis and Bioactivity of Thiazolethioacetamides as Potential Metallo-β-Lactamase InhibitorsAntibiotics, Vol. 9, Pages 99: Synthesis and Bioactivity of Thiazolethioacetamides as Potential Metallo-β-Lactamase InhibitorsAntibiotics doi: 10.3390/antibiotics9030099Authors: Zhang Yan Wang YangMetallo-β-lactamase (MβLs) mediated antibiotic resistance seriously threatens the treatment of bacterial diseases. Recently, we found that thioacetamides can be a potential...
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American Journal of PrimatologyA longitudinal assessment of behavioral development in wild capuchins: Personality is not established in the first 3 yearsHigh intra‐individual variation in mean scores of behavioral traits across time indicated no repeatability. Abstract Animal personality is defined as consistent individual differences across time and situations, but little is known about how or when those differences are established during development. Likewise, several studies described the personality...
Wed Feb 26, 2020 10:37
International Journal of CancerExpression profiles of PRKG1, SDF2L1 and PPP1R12A are predictive and prognostic factors for therapy response and survival in high‐grade serous ovarian cancerAbstract High‐grade serous ovarian cancer (HGS‐EOCs) is generally sensitive to front‐line platinum (Pt)‐based chemotherapy although most patients at an advanced stage relapse with progressive resistant disease. Clinical or molecular data to identify primary resistant cases at diagnosis are not yet available. HGS‐EOC...
Wed Feb 26, 2020 10:37
Skull BasePediatric blunt cerebrovascular injuries: A national trauma database study.Related ArticlesPediatric blunt cerebrovascular injuries: A national trauma database study. J Pediatr Surg. 2020 Jan 31;: Authors: Savoie KB, Shi J, Wheeler K, Xiang H, Kenney BD Abstract BACKGROUND: The incidence of blunt cerebrovascular injuries (BCVIs) in children is unknown. We aimed to determine the rate and consequences of BCVIs in pediatric blunt trauma patients. METHODS: We queried the National Trauma Data...
Wed Feb 26, 2020 10:36
Biomedicine & PharmacotherapyMiR-451a attenuates doxorubicin resistance in lung cancer via suppressing epithelialmesenchymal transition (EMT) through targeting c-MycPublication date: May 2020Source: Biomedicine & Pharmacotherapy, Volume 125Author(s): Li Tao, Wang Shu-Ling, Hao Jing-Bo, Zhang Ying, Hu Rong, Liu Xiang-Qun, Cui Wen-Jie, Zhou Lin-FuBiomedicine & PharmacotherapyTue Feb 25, 2020 13:1518α-Glycyrrhetinic acid (GA) ameliorates fructose-induced nephropathy in mice by suppressing...
Wed Feb 26, 2020 10:35
ScienceDirect Publication: Annals of Allergy, Asthma & ImmunologyPediatric Allergists' Perspectives on the Psychosocial Challenges of Food Allergy and Factors that Support CopingPublication date: Available online 25 February 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Alexandria Bozen, Madeleine K. Kanaley, Olivia Negris, Ruchi S. Gupta, Lisa LombardScienceDirect Publication: Annals of Allergy, Asthma & ImmunologyTue Feb 25, 2020 13:29Prior Authorization FrustrationPublication...
Wed Feb 26, 2020 10:34
Journal of visualized experiments : JoVE,http://www.jove.com/Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems.Related ArticlesUltrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems. J Vis Exp. 2020 Feb 10;(156): Authors: Takaya T, Iwata K Abstract Femtosecond time-resolved stimulated Raman spectroscopy is a promising method of observing the structural dynamics of short-lived transients with near infrared (near-IR)...
Wed Feb 26, 2020 10:33
Nature Communications - current - nature.com science feedsEntropy and interfacial energy driven self-healable polymersNature Communications, Published online: 25 February 2020; doi:10.1038/s41467-020-14911-yDifferent self-healing materials were developed in the past but development of mechanically robust and affordable self-healing materials with high strain and stiffness is challenging. Here the authors develop mechanically robust thermoplastic polyurethane fibers and films capable of autonomous...
Wed Feb 26, 2020 10:33
Radiation protection dosimetryCOMPLIANCE TESTING FOR HUMAN BODY MODEL EXPOSURE TO ELECTROMAGNETIC FIELDS FROM A HIGH-POWER WIRELESS CHARGING SYSTEM FOR DRONES.Related ArticlesCOMPLIANCE TESTING FOR HUMAN BODY MODEL EXPOSURE TO ELECTROMAGNETIC FIELDS FROM A HIGH-POWER WIRELESS CHARGING SYSTEM FOR DRONES. Radiat Prot Dosimetry. 2020 Feb 24;: Authors: Ahn J, Hong SE, Kim H, Chun Y, Choi HD, Kim K, Andrés B, Choi J, Ahn S Abstract Recently, a wireless charging system (WCS) for drones has been extensively...
Wed Feb 26, 2020 10:32
Association of Military Surgeons of the United StatesMemories of the 18th Field Hospital (PW)(Cadre).Related ArticlesMemories of the 18th Field Hospital (PW)(Cadre). Mil Med. 2020 Feb 24;: Authors: Tulgan MH PMID: 32091611 [PubMed - as supplied by publisher]Association of Military Surgeons of the United StatesTue Feb 25, 2020 14:43Use of a Digital Cognitive Aid in the Early Management of Simulated War Wounds in a Combat Environment, a Randomized Trial.Related ArticlesUse of a Digital Cognitive Aid...
Wed Feb 26, 2020 10:32
Cranio-Maxillofacial SurgeryThe Benefit of Bilateral Inferior Alveolar Nerve Block in Managing Postoperative Nausea and Vomiting (PONV) After Mandibular OsteotomyPublication date: Available online 24 February 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): M. Vetter, A. Chatellier, A. Maltezeanu, R. De Mil, H. Bénateau, A. VeyssièreCranio-Maxillofacial SurgeryTue Feb 25, 2020 16:02Mark above section as read Journal of Internal MedicineEpigenetic insights into Multiple Sclerosis disease...
Wed Feb 26, 2020 10:31
Latest Results for Journal of AnesthesiaBatten disease and perioperative complications: a retrospective descriptive studyAbstract Purpose Batten disease or neuronal ceroid lipofuscinosis is the most prevalent neurodegenerative disorder of childhood. Previously reported perioperative complications in children with Batten disease have come mainly from single case reports. The primary aim of the current study was to investigate perioperative complications of patients with Batten disease in the largest...
Wed Feb 26, 2020 10:30
Allergy and Clinical ImmunologyInvestigating Novel Mechanisms Of Acute Angioedema Attacks In Hereditary AngioedemaPublication date: February 2020Source: Journal of Allergy and Clinical Immunology, Volume 145, Issue 2, SupplementAuthor(s): Umesh Singh, Jonathan BernsteinAllergy and Clinical ImmunologyTue Feb 25, 2020 19:01Pneumonia Risk in Asthmatic Children Using Inhaled Corticosteroids: A Nested Case-Control Study in a Birth CohortPublication date: February 2020Source: Journal of Allergy and Clinical...
Wed Feb 26, 2020 10:29
BMC Research NotesValidity and reliability of a dish-based semi-quantitative food frequency questionnaire for assessment of energy and nutrient intake among Iranian adultsThis study aimed to assess the validity and reliability of a dish-based, semi-quantitative food frequency questionnaire (DFFQ) for epidemiological studies in Iran. The DFFQ included 142 items (84 foods and 58 ...BMC Research NotesMon Feb 24, 2020 02:00covRNA: discovering covariate associations in large-scale gene expression dataThe...
Wed Feb 26, 2020 10:29
Medical Mycology Case ReportsIntra-cavitary pulmonary cryptococcoma in poorly controlled diabetes mellitusPublication date: Available online 24 February 2020Source: Medical Mycology Case ReportsAuthor(s): Najibu Kalyango, Richard Kwizera, Joseph B. Baluku, Felix BongominMedical Mycology Case ReportsTue Feb 25, 2020 21:30Mark above section as read European Journal of Surgical Oncology (EJSO)The clinical outcomes of undifferentiated pleomorphic sarcoma (UPS): a single-centre experience of two decades...
Wed Feb 26, 2020 10:28
Popular ScienceChina's missile force is growing at an unprecedented rateVehicles with long-range DF-26 missiles during a military parade in Beijing, China, in September 2015. (Ge jinfh/)China's long-range missiles play a central role in the country's military plans. And, in the event of armed conflict between that nation and the US, they're the weapon the American military worries the most about.Despite their pivotal role in Chinese war-fighting strategy, the service responsible for those missiles,...
Wed Feb 26, 2020 10:27
bioRxiv Subject Collection: Evolutionary BiologyEvolution of the standard genetic code [NEW RESULTS]A near-universal Standard Genetic Code (SGC) implies a single origin for Earthly life. To study this unique event, I compute paths to the SGC, comparing different histories. SGC-like coding tables emerge, using traditional evolutionary mechanisms - a superior evolutionary route can be identified. To objectively measure evolution, progress values from 0 (random coding) to 1 (SGC-like) are defined,...
Wed Feb 26, 2020 10:26
Indian Journal of Cancer : 2014 - 51(1)Indian clinical practice consensus guidelines for the management of squamous cell carcinoma of head and neckKumar Prabhash, Govind Babu, Pankaj Chaturvedi, Moni Kuriakose, Praveen Birur, Anil K Anand, Ashish Kaushal, Abhishek Mahajan, Judita Syiemlieh, Manish Singhal, Munish Gairola, Prakash Ramachandra, Sumit Goyal, Subashini John, Rohit Nayyar, Vijay M Patil, Vishal Rao, Vikas Roshan, GK RathIndian Journal of Cancer 2020 57(5):1-5 Head and neck cancers (HNCs)...
Wed Feb 26, 2020 10:26
Translational Genomics for Rare Cancers: Challenges and Opportunity.Related ArticlesTranslational Genomics for Rare Cancers: Challenges and Opportunity. Semin Cancer Biol. 2020 Feb 21;: Authors: Tan AC, Huang PH PMID: 32092353 [PubMed - as supplied by publisher]Rare CancersTue Feb 25, 2020 14:44Neuroendocrine tumors of the gastrointestinal tract and pancreas: Is it also a challenge for pediatricians?Related ArticlesNeuroendocrine tumors of the gastrointestinal tract and pancreas: Is it also a challenge...
Wed Feb 26, 2020 10:25
CancersCancers, Vol. 12, Pages 533: A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2Cancers, Vol. 12, Pages 533: A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2 Cancers doi: 10.3390/cancers12030533 Authors: Man-Hong Leung Ho Tsoi Chun Gong Ellen PS Man Stefania Zona Shang Yao Eric W.-F. Lam Ui-Soon Khoo Breast cancer is the most common type of female cancer. Reactive oxygen...
Wed Feb 26, 2020 10:24
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,Metastatic renal cell carcinoma to the pancreas and subcutaneous tissue 10 years after radical nephrectomy: a case reportMetastatic renal cell carcinoma to the pancreas and subcutaneous tissue 10 years after radical nephrectomy: a case report: AbstractBackgroundSynchronous renal cell carcinoma metastasizing to the pancreas and subcutaneous tissue is very rare. Unusual metastatic sites require attention...
Wed Feb 26, 2020 10:21
The Association Between Physiological Noise Levels and Speech Understanding in Noise: Objectives: Traditionally, elevated hearing thresholds have been considered to be the main contributors to difficulty understanding speech in noise; yet, patients will often report difficulties with speech understanding in noise despite having audiometrically normal hearing. The purpose of this cross-sectional study was to critically evaluate the relationship of various metrics of auditory function (behavioral thresholds...
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Health-Related Quality of Life With Cochlear Implants: The Children's Perspective: Objectives: The objective of this study was to assess self-reported health-related quality of life (HR-QOL) in a group of children with cochlear implants (CIs) and to compare their scores to age- and gender-matched controls. The authors also assessed the agreement between proxy- and self-reported HR-QOL in the CI group and examined individual and environmental variables that could be associated with higher or lower...
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Improving Sensitivity of the Digits-In-Noise Test Using Antiphasic Stimuli: Objectives: The digits-in-noise test (DIN) has become increasingly popular as a consumer-based method to screen for hearing loss. Current versions of all DINs either test ears monaurally or present identical stimuli binaurally (i.e., diotic noise and speech, NoSo). Unfortunately, presentation of identical stimuli to each ear inhibits detection of unilateral sensorineural hearing loss (SNHL), and neither diotic nor monaural...
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Oscillopsia in Bilateral Vestibular Hypofunction: Not Only Gain But Saccades Too: Objectives: Oscillopsia is a disabling condition for patients with bilateral vestibular hypofunction (BVH). When the vestibulo-ocular reflex is bilaterally impaired, its ability to compensate for rapid head movements must be supported by refixation saccades. The objective of this study is to assess the relationship between saccadic strategies and perceived oscillopsia.Design: To avoid the possibility of bias due to...
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Improving Cochlear Implant Performance in the Wind Through Spectral Masking Release: A Multi-microphone and Multichannel Strategy: Objectives: Adopting the omnidirectional microphone (OMNI) mode and reducing low-frequency gain are the two most commonly used wind noise reduction strategies in hearing devices. The objective of this study was to compare the effectiveness of these two strategies on cochlear implant users' speech-understanding abilities and perceived sound quality in wind noise. We also...
09:09
A Comparison of Intracochlear Pressures During Ipsilateral and Contralateral Stimulation With a Bone Conduction Implant: Objectives: To compare contralateral to ipsilateral stimulation with percutaneous and transcutaneous bone conduction implants.Background: Bone conduction implants (BCIs) effectively treat conductive and mixed hearing losses. In some cases, such as in single-sided deafness, the BCI is implanted contralateral to the remaining healthy ear in an attempt to restore some of the benefits...
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Links of Prosodic Stress Perception and Musical Activities to Language Skills of Children With Cochlear Implants and Normal Hearing: Objectives: A major issue in the rehabilitation of children with cochlear implants (CIs) is unexplained variance in their language skills, where many of them lag behind children with normal hearing (NH). Here, we assess links between generative language skills and the perception of prosodic stress, and with musical and parental activities in children with CIs and NH....
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Human Frequency Following Responses to Vocoded Speech: Amplitude Modulation Versus Amplitude Plus Frequency Modulation: Objectives: The most commonly employed speech processing strategies in cochlear implants (CIs) only extract and encode amplitude modulation (AM) in a limited number of frequency channels. Zeng et al. (2005) proposed a novel speech processing strategy that encodes both frequency modulation (FM) and AM to improve CI performance. Using behavioral tests, they reported better speech,...
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Barriers and Facilitators to Cochlear Implant Uptake in Australia and the United Kingdom: Objectives: Hearing loss (HL) affects a significant proportion of adults aged >50 years by impairing communication and social connectedness and, due to its high prevalence, is a growing global concern. Cochlear implants (CIs) are effective devices for many people with severe or greater sensorineural HL who experience limited benefits from hearing aids. Despite this, uptake rates globally are low among adults....
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Relationship Between Diet, Tinnitus, and Hearing Difficulties: Objectives: Diet may affect susceptibility of the inner ear to noise and age-related effects that lead to tinnitus and hearing loss. This study used complementary single nutrient and dietary pattern analysis based on statistical grouping of usual dietary intake in a cross-sectional analysis of tinnitus and hearing difficulties in a large population study sample.Design: The research was conducted using the UK Biobank resource. Tinnitus...
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Limitations of the Envelope Difference Index as a Metric for Nonlinear Distortion in Hearing Aids: Objectives: The envelope difference index (EDI) compares the envelopes of two signals. It has been used to measure nonlinear distortion in hearing aids, but it also responds to linear processing. This article compares linear and nonlinear processing effects on the EDI.Design: The EDI for spectral tilt and peak clipping distortion is computed to illustrate the effects of linear and nonlinear signal modifications....
09:08
The Effect of Musical Training and Working Memory in Adverse Listening Situations: Objectives: Speech-in-noise (SIN) perception is essential for everyday communication. In most communication situations, the listener requires the ability to process simultaneous complex auditory signals to understand the target speech or target sound. As the listening situation becomes more difficult, the ability to distinguish between speech and noise becomes dependent on recruiting additional cognitive resources,...
09:07
Masking Release for Speech-in-Speech Recognition Due to a Target/Masker Sex Mismatch in Children With Hearing Loss: Objectives: The goal of the present study was to compare the extent to which children with hearing loss and children with normal hearing benefit from mismatches in target/masker sex in the context of speech-in-speech recognition. It was hypothesized that children with hearing loss experience a smaller target/masker sex mismatch benefit relative to children with normal hearing due to...
09:07
Quantifying the Range of Signal Modification in Clinically Fit Hearing Aids: Objectives: Hearing aids provide various signal processing techniques with a range of parameters to improve the listening experience for a hearing-impaired individual. In previous studies, we reported significant differences in signal modification for mild versus strong signal processing in commercially available hearing aids. In this study, the authors extend this work to clinically prescribed hearing aid fittings based...
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Psychobiological Responses Reveal Audiovisual Noise Differentially Challenges Speech Recognition: Objectives: In noisy environments, listeners benefit from both hearing and seeing a talker, demonstrating audiovisual (AV) cues enhance speech-in-noise (SIN) recognition. Here, we examined the relative contribution of auditory and visual cues to SIN perception and the strategies used by listeners to decipher speech in noise interference(s).Design: Normal-hearing listeners (n = 22) performed an open-set...
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A Cross-Sectional Study of the Prevalence and Factors Associated With Tinnitus and/or Hyperacusis in Children AbstractObjectives: The aim of this study was to determine the prevalence of tinnitus and/or hyperacusis in Danish children aged 10 to 16 years, and to assess associations between tinnitus or hyperacusis and other relevant factors.Design: A cross-sectional study based on a previously established child cohort. A total of 501 children were enrolled in the project. The study was performed in...
09:06
Long-Term Variability of Distortion-Product Otoacoustic Emissions in Infants and Children and Its Relation to Pediatric Ototoxicity Monitoring: Objective: Distortion-product otoacoustic emissions (DPOAEs) provide a rapid, noninvasive measure of outer hair cell damage associated with chemotherapy and are a key component of pediatric ototoxicity monitoring. Serial monitoring of DPOAE levels in reference to baseline measures is one method for detecting ototoxic damage. Interpreting DPOAE findings in...
09:05
Effects of Simulated and Profound Unilateral Sensorineural Hearing Loss on Recognition of Speech in Competing Speech: Objectives: Unilateral hearing loss (UHL) is a condition as common as bilateral hearing loss in adults. Because of the unilaterally reduced audibility associated with UHL, binaural processing of sounds may be disrupted. As a consequence, daily tasks such as listening to speech in a background of spatially distinct competing sounds may be challenging. A growing body of subjective and...
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Age Effects on Cochlear Reflectance in Adults: Objectives: Cochlear reflectance (CR) is the cochlear contribution to ear-canal reflectance. CR is a type of otoacoustic emission that is calculated as a transfer function between forward pressure and reflected pressure. The purpose of this study was to assess effects of age on CR in adults and interactions among age, sex, and hearing loss.Design: Data were collected from 60 adults selected for their age (e.g., 20–29, 30–39, 40–49, 50–59, 60–69, 70–79...
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CircPSMC3 inhibits cell proliferation and induces cell apoptosis in nasopharyngeal carcinoma by downregulating ROCK1.: Related ArticlesCircPSMC3 inhibits cell proliferation and induces cell apoptosis in nasopharyngeal carcinoma by downregulating ROCK1.Eur Rev Med Pharmacol Sci. 2020 Feb;24(3):1219-1225Authors: Guo DQ, Liu F, Zhang L, Bian NN, Liu LY, Kong LX, Wang ZGAbstract OBJECTIVE: Currently, the importance of circular RNAs in malignant tumors has attracted much attention. However, the...
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Impact of delayed adjuvant therapy after surgery in p16 positive oropharyngeal cancer: a retrospective analysis.: Related ArticlesImpact of delayed adjuvant therapy after surgery in p16 positive oropharyngeal cancer: a retrospective analysis.Eur Rev Med Pharmacol Sci. 2020 Feb;24(3):1211-1218Authors: Sievert M, Goncalves M, Mueller SK, Hecht M, Pflaum A, Grundtner P, Iro H, Gostian AOAbstract OBJECTIVE: This study aimed to clarify the impact of delayed adjuvant therapy on the outcome of HPV...
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Vocal Turn-Taking Between Mothers and Their Children With Cochlear Implants: Objectives: The primary objective of the study was to examine the occurrence and temporal structure of vocal turn-taking during spontaneous interactions between mothers and their children with cochlear implants (CI) over the first year after cochlear implantation as compared with interactions between mothers and children with normal hearing (NH).Design: Mothers' unstructured play sessions with children with CI (n = 12) were...
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Discovery of novel molecular characteristics and cellular biological properties in ameloblastoma.: Related ArticlesDiscovery of novel molecular characteristics and cellular biological properties in ameloblastoma.Cancer Med. 2020 Feb 25;:Authors: Kondo S, Ota A, Ono T, Karnan S, Wahiduzzaman M, Hyodo T, Lutfur Rahman M, Ito K, Furuhashi A, Hayashi T, Konishi H, Tsuzuki S, Hosokawa Y, Kazaoka YAbstract Ameloblastoma is a rare odontogenic benign tumor accounting for less than 1% of head and...
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Serum levels of interleukin-32 and interleukin-6 in granulomatosis with polyangiitis and microscopic polyangiitis: association with clinical and biochemical findings.: Related ArticlesSerum levels of interleukin-32 and interleukin-6 in granulomatosis with polyangiitis and microscopic polyangiitis: association with clinical and biochemical findings.Eur Cytokine Netw. 2019 Dec 01;30(4):151-159Authors: Krajewska Wojciechowska J, Kościelska-Kasprzak K, Krajewski W, Morawski KAbstract BACKGROUND:...
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Oman Med J. 2018 Mar; 33(2): 97–103.doi: 10.5001/omj.2018.20PMCID: PMC5889841PMID: 29657677Immunoglobulin G4-Related Disease: An UpdateAbdullah Al-Mujaini,1,* Murtadha Al-Khabori,2 Kashinatha Shenoy,1 and Upender Wali1Author information Article notes Copyright and License information Disclaimer1Department of Ophthalmology, College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, Oman2Department of Hematology, College of Medicine and Health Sciences, Sultan Qaboos University...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,Metastatic renal cell carcinoma to the pancreas and subcutaneous tissue 10 years after radical nephrectomy: a case reportMetastatic renal cell carcinoma to the pancreas and subcutaneous tissue 10 years after radical nephrectomy: a case report: AbstractBackgroundSynchronous renal cell carcinoma metastasizing to the pancreas and subcutaneous tissue is very rare. Unusual metastatic sites require attention...
Wed Feb 26, 2020 10:21
Ultrasonography findings in immunoglobulin G4-related lymphadenopathy: a report of two cases.: Related ArticlesUltrasonography findings in immunoglobulin G4-related lymphadenopathy: a report of two cases.Med Ultrason. 2020 Mar 01;22(1):107-109Authors: Morisaki T, Fukuhara T, Matsuda E, Moritani S, Miyake N, Koyama S, Fujiwara K, Takeuchi HAbstract Lymphadenopathy is frequently observed in immunoglobulin G4 (IgG4)-related disease in some cases, and such cases are known as IgG4-related lymphadenopathy....
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A Mouse Model of Dysphagia After Facial Nerve Injury.: Related ArticlesA Mouse Model of Dysphagia After Facial Nerve Injury.Laryngoscope. 2020 Feb 25;:Authors: Welby L, Ukatu CC, Thombs L, Lever TEAbstract OBJECTIVE: Dysphagia is common following facial nerve injury; however, research is sparse regarding swallowing-related outcomes and targeted treatments. Previous animal studies have used eye blink and vibrissae movement as measures of facial nerve impairment and recovery. The purpose of...
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Reconfiguration of Upper Airway Stimulation Devices Utilizing Awake Endoscopy.: Related ArticlesReconfiguration of Upper Airway Stimulation Devices Utilizing Awake Endoscopy.Laryngoscope. 2020 Feb 25;:Authors: Meleca JB, Kominsky AHAbstract OBJECTIVES: Determine the rates of, reasons for, and effectiveness of device reprogramming utilizing in-office awake endoscopy (AE) in subjects who underwent upper airway stimulation (UAS) surgery. STUDY DESIGN: Retrospective chart review. ...
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Evolving Treatment of Frontal Sinus Cholesteatoma: A Case Report.: Related ArticlesEvolving Treatment of Frontal Sinus Cholesteatoma: A Case Report.Perm J. 2020;24:Authors: Tejani N, Kshirsagar R, Song B, Liang JAbstract INTRODUCTION: Cholesteatomas are lined by squamous epithelium, contain keratin debris, and can cause bony erosion. Although commonly found in the middle ear space and mastoid, cholesteatomas may develop in adjacent structures including the paranasal sinuses. Frontal sinus...
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Gonorrhea-positive sinus cultures in a 15-year-old with allergic fungal sinusitis.: Related ArticlesGonorrhea-positive sinus cultures in a 15-year-old with allergic fungal sinusitis.JAAPA. 2020 Mar;33(3):31-33Authors: Donner K, Kou YF, Tomkies A, Rakheja D, Mitchell RB, Shah GAbstract This article describes a patient with gonorrhea in sinus cultures and allergic fungal sinusitis. A multidisciplinary team was assembled to deliver the results to the minor patient and her family and provide...
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Pilot Evaluation of Sheep as In Vivo Model for Cochlear Implantation.: Related ArticlesPilot Evaluation of Sheep as In Vivo Model for Cochlear Implantation.Otol Neurotol. 2020 Feb 24;:Authors: Kaufmann CR, Tejani VD, Fredericks DC, Henslee AM, Sun DQ, Abbas PJ, Hansen MRAbstract OBJECTIVES: The rise in the use of cochlear implants (CIs) has continued to fuel research aimed at improving surgical approaches and the preservation of residual hearing. Current in vivo models involve small animals...
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The Effectiveness of bFGF in the Treatment of Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis.: Related ArticlesThe Effectiveness of bFGF in the Treatment of Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis.Otol Neurotol. 2020 Feb 24;:Authors: Huang J, Teh BM, Eikelboom RH, Han L, Xu G, Yao X, Hu Y, Zheng M, Shen YAbstract OBJECTIVE: To investigate the effectiveness of basic fibroblast growth factor (bFGF) versus placebo or no intervention in the...
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Clinical Profiles of DFNA11 at Diverse Stages of Development and Aging in a Large Family Identified by Linkage Analysis.: Related ArticlesClinical Profiles of DFNA11 at Diverse Stages of Development and Aging in a Large Family Identified by Linkage Analysis.Otol Neurotol. 2020 Feb 24;:Authors: Yamamoto N, Mutai H, Namba K, Goto F, Ogawa K, Matsunaga TAbstract HYPOTHESIS: The phenotype of DFNA11 consists of specific features at diverse developmental and age stages. BACKGROUND: Only...
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Deep Neck Abscesses in Children: An Italian Retrospective Study.: Related ArticlesDeep Neck Abscesses in Children: An Italian Retrospective Study.Pediatr Emerg Care. 2020 Feb 24;:Authors: Donà D, Gastaldi A, Campagna M, Montagnani C, Galli L, Trapani S, Pierossi N, De Luca M, DʼArgenio P, Tucci FM, De Vincentiis G, Grotto P, Da Mosto MC, Frigo AC, Volo T, Emanuelli E, Martini A, Da Dalt LAbstract BACKGROUND: Retropharyngeal and parapharyngeal abscesses (RPAs, PPAs) usually affect young children....
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Reconstruction of Complex Oromandibular Defects in Head and Neck Cancer: Role of the Chimeric Subscapular Free Flap.: Related ArticlesReconstruction of Complex Oromandibular Defects in Head and Neck Cancer: Role of the Chimeric Subscapular Free Flap.J Craniofac Surg. 2020 Feb 24;:Authors: Molteni G, Gazzini L, Plotegher C, Lanaro L, Fior A, Marchioni D, Nocini PFAbstract The purpose of this study is to present the chimeric scapula tip-free flap as a reconstructive choice in composite head...
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Distant metastasis of salivary gland cancer: Incidence, management, and outcomes.: Related ArticlesDistant metastasis of salivary gland cancer: Incidence, management, and outcomes.Cancer. 2020 Feb 25;:Authors: Mimica X, McGill M, Hay A, Karassawa Zanoni D, Shah JP, Wong RJ, Ho A, Cohen MA, Patel SG, Ganly IAbstract BACKGROUND: Distant metastases (DMs) are the primary cause of treatment failure in patients with salivary gland carcinoma. There is no consensus on the standard treatment. ...
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What is the optimal timing for implant placement in oral cancer patients? A scoping literature review.: Related ArticlesWhat is the optimal timing for implant placement in oral cancer patients? A scoping literature review.Oral Dis. 2020 Feb 25;:Authors: Alberga JM, Vosselman N, Korfage A, Delli K, Witjes M, Raghoebar GM, Vissink AAbstract BACKGROUND: Oral cancer patients can benefit from dental implant placement. Traditionally implants are placed after completing oncologic treatment (secondary...
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Is Empirical Treatment a Reasonable Strategy for Laryngopharyngeal Reflux? A Contemporary Review.: Related ArticlesIs Empirical Treatment a Reasonable Strategy for Laryngopharyngeal Reflux? A Contemporary Review.Clin Otolaryngol. 2020 Feb 25;:Authors: Lechien JR, Bock JM, Carroll TL, Akst LMAbstract BACKGROUND: Diagnosis and treatment of presumed laryngopharyngeal reflux (LPR) remains controversial. Empiric medication trials remain widespread for suspected LPR despite emerging evidence against...
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Tuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini.: Related ArticlesTuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini.Dev Cell. 2020 Feb 24;52(4):477-491.e8Authors: Ramos SI, Makeyev EV, Salierno M, Kodama T, Kawakami Y, Sahara SAbstract Most adult neurons and glia originate from radial glial progenitors (RGs), a type of...
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Self-channel-and-spatial-attention neural network for automated multi-organ segmentation on head and neck CT images.: Related ArticlesSelf-channel-and-spatial-attention neural network for automated multi-organ segmentation on head and neck CT images.Phys Med Biol. 2020 Feb 25;:Authors: Gou S, Tong N, Qi SX, Yang S, Chin RK, Sheng KAbstract Accurate segmentation of organs-at-risk (OARs) is necessary for adaptive head and neck (H&N) cancer treatment planning but manual delineation is tedious,...
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Parotidectomy via Individualized Mini-Blair Incision.: Related ArticlesParotidectomy via Individualized Mini-Blair Incision.ORL J Otorhinolaryngol Relat Spec. 2020 Feb 25;:1-9Authors: Khafif A, Niddal A, Azoulay O, Holostenco V, Masalha MAbstract BACKGROUND: The modified Blair incision is the standard facial incision for the vast majority of parotid gland lesions. We utilize three types of incisions: "classic mini-Blair" for parotid body tumors, "cervical mini-Blair" for parotid tail tumors,...
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Dopaminergic and Adrenergic Pathways as Targets for Drug Repurposing in the Neuroimmune Network: AbstractDopamine, noradrenaline and adrenaline are catecholamines, and are all produced along the same metabolic pathway. Their discovery dates back to the early 1900s, and they were appreciated until the second half of the century mainly for their role in the brain and in the regulation of autonomic functions. Nonetheless, in the 1970s characterization of the key role of sympathoadrenergic nerve fibers...
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Ellagic Acid Ameliorates Lung Inflammation and Heart Oxidative Stress in Elastase-Induced Emphysema Model in Rat: Abstract Chronic obstructive pulmonary disease (COPD) is one of the most important factors in the progress of cardiovascular disease (CVD) which is associated with limited airflow and alveolar demolition. The aim of this study is to investigate the possible protective effect of ellagic acid (EA), as a natural anti-oxidant, against pulmonary arterial hypertension (PAH) and development...
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Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomas: Condition: Malignant Melanoma Interventions: Drug: Fluvastatin; Other: RNA-sequencing; Other: Gene expression profiling Sponsor: Case Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
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Predictive Value of 10 microRNA in Thyroid Cytologies of Undetermined Type: Condition: Thyroid Cancer Intervention: Diagnostic Test: Signature of 10 microRNA for patients with bethesda classification 3, 4 or 5 Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle Not yet recruiting (Source: ClinicalTrials.gov)
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IMaging Pilot Study of the αvβ6 Integrin Radiotracer [18F]-A20FMDV2 in PAtients With Solid Cancer Types: Condition: Cancer Intervention: Procedure: PET Scan Sponsor: Queen Mary University of London Active, not recruiting (Source: ClinicalTrials.gov)
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Rituximab, Venetoclax, and Bortezomib for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Conditions: High Grade B-Cell Lymphoma, Not Otherwise Specified; Recurrent Burkitt Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory Burkitt Lymphoma; Refractory Diffuse Large B-Cell Lymphom a; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements Interventions:...
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Chemical constituents, antioxidant and cytotoxicity properties of Leonotis leonurus used in the folklore management of neurological disorders in the Eastern Cape, South Africa: AbstractIn the present study, we evaluated the phytochemical compounds and antioxidant properties of chloroform, ethanol and acetone extracts for leaves and flowers of Leonutus leonurus (L. leonurus) alongside with their cytotoxic effects on human cervical carcinoma (HeLa) cell lines. The phytochemical compounds present in...
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Calpain suppresses cell growth and invasion of glioblastoma multiforme by producing the cleavage of filamin A: AbstractBackgroundFilamin A is the most widely expressed isoform of filamin in mammalian tissues. It can be hydrolyzed by Calpain, producing a 90-kDa carboxyl-terminal fragment (ABP90). Calpeptin is a chemical inhibitor of Calpain, which can inhibit this effect. It has been shown that ABP90 acts as a transcription factor which is involved in mediating cell signaling. However, the significance...
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All Wrong About Alzheimer's: Alzheimer's disease, a condition characterized by an accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, affects an estimated 5 million Americans; this number is expected to reach 14 million by 2060.1 With no known cure, researchers are scrambling to find treatments, often with a misguided focus on drugs designed to remove excess beta-amyloid in the brain.Drug development for Alzheimer's has so far been a dismal failure, with 300 failed trials...
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Heart Attack or Panic Attack? How to Tell the Difference: According to the U.S. Centers for Disease Control and Prevention,1 nearly 805,000 Americans have a heart attack each year, and 605,000 are first heart attacks. Knowing the risk factors, symptoms and how to take early action will increase your chances of survival.However, what may look and feel like an apparent heart attack may actually be a panic attack, and according to researchers, the cost of misdiagnosing noncardiac chest pain is high.2...
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Vestibular Schwannoma Causing Unilateral Facial Pain in 20-Year-Old Patient: Ear, Nose &Throat Journal, Ahead of Print.
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Creating a Validated Simulation Training Curriculum in Otolaryngology: AbstractPurpose of ReviewSimulation-based training is an integral component of surgical training. It allows practice of technical skills within a safe environment without compromising patient safety. This article seeks to review current virtual and non-virtual reality simulation models within the literature and review their validation status.Recent FindingsMany simulation models exist within otolaryngology and are currently being...
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ROS-induced oxidative damage in lymphocytes ex vivo/in vitro from healthy individuals and MGUS patients: protection by myricetin bulk and nanoforms: AbstractWe investigated the protective role of myricetin bulk and nanoforms, against reactive oxygen species (ROS)-induced oxidative stress caused by hydrogen peroxide and tertiary-butyl hydro peroxide in lymphocytes in vitro from healthy individuals and those from pre-cancerous patients suffering with monoclonal gammopathy of undetermined significance...
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Does injury of the thalamocortical connection between the mediodorsal nucleus of the thalamus and the dorsolateral prefrontal cortex affect motor recovery after cerebral infarct?: AbstractWe assessed the state of the thalamocortical connection between the mediodorsal nucleus (MD) and the dorsolateral prefrontal cortex (DLPFC) in patients with corona radiata infarct using diffusion tensor tractography (DTT). Altogether, 110 patients with corona radiata infarct were recruited, all of whom underwent...
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Selenium and antioxidant levels in children with intractable epilepsy receiving ketogenic diet: AbstractKetogenic diet is a high-fat, low-carbohydrate, and adequate-protein diet. It is well-established as a treatment option for drug-resistant childhood epilepsies. Our study aimed to evaluate Selenium levels and oxidative stress in children receiving ketogenic diet for intractable seizures for 6 months. This is a comparative case–control study included 90 children under 6 years age. They were subdivided...
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Progressive hemiparesis reveals X-linked adrenoleukodystrophy in a 3.5-year-old boy:
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Caries prevalence in preterm and low birth weight children: This review of the prevalence of dental caries in preschool children born preterm and/or with a low birth weight included 59 observational studies suggesting caries prevelence was similar to full term children of normal weight. However, the certainty of teh evidence was very low. The post Caries prevalence in preterm and low birth weight children appeared first on National Elf Service.
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Gestational pulmonary giant cell carcinoma - An autopsy report: Rushabh Shah, Pradeep Vaideeswar, Tasneem CochinIndian Journal of Cancer 2020 57(1):102-104Cancer is an uncommon event in pregnancy. The most common gestational cancers arise from the breast and cervix. Although lung cancer is the most common malignancy, its occurrence in pregnancy is a distinctly rare event. Diagnosing it during pregnancy is an additional challenge as the pregnancy, common respiratory ailments, and the lung cancer can...
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Diagnostic value of a power Doppler ultrasound-based malignancy index for differentiating malignant and benign solid breast lesions: Ali Enshaei, Afshin Mohammadi, Seyed Babak Moosavi Toomatari, Zahra Yekta, Seyed Ehsan Moosavi Toomatari, Mohammad Ghasemi-Rad, Saber Zafar Shamspour, Zahra Karimi Sarabi, Nariman SepehrvandIndian Journal of Cancer 2020 57(1):44-48Background: Power Doppler ultrasound (PDUS) can provide useful information regarding the vascularity of breast lesions. The aim of this study...
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Scrambler therapy: A ray of hope for refractory chemotherapy-induced peripheral neuropathy: Deepti Ahuja, Sachidanand Jee Bharati, Nishkarsh Gupta, Vinod Kumar, Sushma BhatnagarIndian Journal of Cancer 2020 57(1):93-97Scrambler therapy (ST) is a novel noninvasive modality for treatment of chronic neuropathic and cancer pain using 5 artificial neurons. The principle with Scrambler Therapy is that synthetic "non-pain" information is transmitted by C fiber surface receptors. Chemotherapy-induced peripheral...
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Chemo-radiation outcomes for esophageal cancer: A reflection from a tertiary cancer center on selection of patients for more aggressive therapy: Janaki Gururajachar Manur, M G John Sebastian, Savitha Mary DavidIndian Journal of Cancer 2020 57(1):84-88Introduction: Most esophageal cancer patients present with poor nutritional status and may not tolerate radical treatment. Aim: We aim to identify patients who are good candidates for chemo-radiation (CTRT). Materials and Methods: Fifty-four patients...
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Characteristics and significance of changes of thrombomodulin and plasma protein C in patients with cancer before and after PICC: Min Yan, Xiang-Tao Pan, Xu Cheng, Ye LuIndian Journal of Cancer 2020 57(1):27-30Objective: This study aimed to evaluate the changes and clinical significance of thrombomodulin (TM) and plasma protein C (PC) in patients with cancer before and after peripherally inserted central catheter placement (PICC). Materials and Methods: The levels of plasma TM and PC in 35 patients...
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Juvenile myelomonocytic leukemia: A case series of a rare hematological disease: Kalaivani S Subramanian, Sree Rekha Jinkala, Rakhee Kar, Debdatta Basu, Biswajit DubashiIndian Journal of Cancer 2020 57(1):105-108Juvenile myelomonocytic leukemia (JMML) is a rare but frequently lethal clonal myeloproliferative neoplasm (MPN) of childhood. JMML accounts for less than 1% of childhood leukemias.[1] It predominately affects young children under the age of 4 years and is characterised by the overproduction...
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Infrahyoid flap revisited – A head and neck surgical perspective in the Indian setting: Manikandan Venkatasubramaniyan, Suhas Kodasoge Rajappa, Mudit Agarwal, Anshu Chopra, Abhishek Singh, Rajiv PaulIndian Journal of Cancer 2020 57(1):62-69Purpose: In India, head and neck cancer contributes to about 35% of all malignancies. Among head and neck squamous cell cancers, buccal mucosa and tongue are the most common subsites. Reconstruction of defects after resection of primary in these subsites with acceptable...
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Middle ear adenoma with neuroendocrine differentiation: Report of a rare case: Shakti Kumar Yadav, Roshina Naeem, Amitabh Sharma, Sompal Singh, Namrata Sarin, Sonam Kumar PruthiIndian Journal of Cancer 2020 57(1):98-101Middle ear adenoma with neuroendocrine differentiation (MEA-ND) is also called as neuroendocrine adenoma. Neuroendocrine tumors are rarely seen in the head and neck region and are even more rare in the middle ear. Clinical and radiological findings are non-specific and seldom suggest...
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Efficacy and tolerability of nimotuzumab in combination with chemotherapy in recurrent and metastatic squamous cell carcinoma of head and neck at a cancer center in Northern India: Abhishek Yadav, Pankaj Goyal, Chaturbhuj R Agrawal, Sneha J Bothra, Parveen Jain, Kumardeep Dutta Choudhury, Sunil Kumar Gupta, Manish Sharma, Rajat Bajaj, Amitabh Upadhyay, Prashanta Dash, Dinesh C DovalIndian Journal of Cancer 2020 57(1):76-83Introduction: Squamous cell carcinoma of head and neck (SCCHN) account for...
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Efficacy and tolerability of nimotuzumab in combination with chemotherapy in recurrent and metastatic squamous cell carcinoma of head and neck at a cancer center in Northern India: Abhishek Yadav, Pankaj Goyal, Chaturbhuj R Agrawal, Sneha J Bothra, Parveen Jain, Kumardeep Dutta Choudhury, Sunil Kumar Gupta, Manish Sharma, Rajat Bajaj, Amitabh Upadhyay, Prashanta Dash, Dinesh C DovalIndian Journal of Cancer 2020 57(1):76-83Introduction: Squamous cell carcinoma of head and neck (SCCHN) account for...
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Campylobacter chicken liver outbreak adds to evidence of risk: Researchers have called for increased awareness to reduce the risk of Campylobacter outbreaks linked to incorrectly cooked chicken liver dishes.Communication from food safety and public health authorities may be required. Any strategy should ensure the risk profile of poultry liver-containing dishes is raised and availability of evidence-based preventative strategies for food preparation promoted, according to the study published in the...
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MiR-214 Mediates Cell Proliferation and Apoptosis of Nasopharyngeal Carcinoma Through Targeting Both WWOX and PTEN: Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print. AbstractBackground: Nasopharyngeal carcinoma (NPC) was highly prevalent with poor prognosis among the patients. MiR-214 reported as an important NPC biomarker was associated with regulation of biological functions. This study aimed to investigate interactions between miR-214, PTEN, and WWOX and their effect on AKT signaling...
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Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection: In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were reviewed for common CT findings in relationship to the time between symptom onset and the initial CT scan (i.e. early, 0-2 days (36 patients), intermediate 3-5 days (33 patients), late 6-12 days (25...
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Happiness at Your Fingertips: Assessing Mental Health with Smartphone Photoplethysmogram-Based Heart Rate Variability Analysis: Telemedicine and e-Health, Ahead of Print.AbstractBackground: Heart rate variability (HRV) provides essential mental health information for clinical diagnosis, telemedicine, preventive medicine, and public health; however, the lack of a convenient detection method limits its potential.Objective: This study aims to investigate the feasibility and credibility of smartphone...
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Surgical Management of Medication-Related Osteonecrosis of the Jaw Patients Related to Dental Implants: Objectives: The aim of the present study is to report a case series of patients with peri-implant medication-related osteonecrosis of the jaw (MRONJ), in particular describing the onset of the condition and surgical treatment outcome.Material and Methods: Fifteen consecutive patients with clinical diagnosis of peri-implant MRONJ were retrospectively included in the study. The sample was stratified...
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Comparison of Quality of Life Before and After Septoplasty With Short Form-36: The authors aimed to evaluate quality of life after septal surgery with Short Form-36 survey, and the effectiveness of the survey. Nasal symptoms (nasal obstruction, facial pain, catarrh), and general quality of life (using the Turkish version of the Short Form-36 questionnaire) were assessed preoperatively and at 1st and 6th postoperative months. Acoustic rhinometry and rhinomanometry were assessed preoperatively and...
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Transbrow Excision Blepharoplasty for Upper Eyelid Dermatochalasis: A Modified Approach: Backgrounds: Many aging women with upper lid dermatochalasis pluck their lower lateral eyebrows to combat lateral drooping. The authors present and evaluate outcomes of a modified excision blepharoplasty method performed using a transbrow excision approach instead of infra/suprabrow access to more efficiently correct upper eyelid dermatochalasis.Methods: The authors conducted a retrospective review of 192 patients...
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Influence of Inhalation Injury on Incidence, Clinical Profile and Recovery Pattern of Dysphagia Following Burn Injury: AbstractInhalation injury is predictive of dysphagia post burns; however, the nature of dysphagia associated with inhalation burns is not well understood. This study describes the clinical profile and recovery pattern of swallowing following inhalation burn injury. All patients admitted 2008–2017 with confirmed inhalation burns on laryngoscopy and managed by speech-language pathology...
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Nondiagnostic Fine-Needle Aspiration Biopsy of Thyroid Nodules: Outcomes and Determinants: Thyroid, Ahead of Print.AbstractBackground: Nondiagnostic results are common following fine-needle aspiration biopsy (FNAB) of thyroid nodules, but recommendations for the management of these patients vary. We sought to determine the outcomes and predictors of nondiagnostic FNABs in a single-center cohort of patients undergoing thyroid nodule evaluation.Methodology: We identified all first time ultrasound-guided...
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Patterns of Use, Efficacy, and Safety of Treatment Options for Patients with Graves' Disease: A Nationwide Population-Based Study: Thyroid, Ahead of Print.AbstractBackground: Considerable uncertainty remains about the pattern of use of treatment options for Graves' disease (GD) and their comparative effectiveness and safety.Methods: Between 2005 and 2013, we identified patients with GD who received antithyroid drugs (ATDs), radioactive iodine (RAI) or surgery, and were represented in a large administrative...
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Decision-Analytic Modeling Studies in Prevention and Treatment of Iodine Deficiency and Thyroid Disorders: A Systematic Overview: Thyroid, Ahead of Print.AbstractBackground: Prevention and treatment of iodine deficiency-related diseases remain an important public health challenge. Iodine deficiency can have severe health consequences, such as cretinism, goiter, or other thyroid disorders, and it has economic implications. Our aim was to give an overview of studies applying decision-analytic modeling...
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PRO/EDR> Meningitis, meningococcal - Costa Rica: 3rd-gen. cephalosporin resistance, RFI: Meningitis - Neisseria -- Costa RicaA 50-year-old man and a senior became the 1st 2 people in Costa Rica -- and in the Americas -- found to be infected with the bacteria most resistant to antibiotics used in the treatment of meningitis and meningococcal septicemia that cause serious brain damage and even death.The Centro Nacional de Referencia en Bacteriología (CNRB) -- National Center of Reference in Bacteriology,...
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PRO/AH/EDR> Plague - Congo DR (02): (IT) bubonic, pneumonic, fatal: Plague -- DR CongoOn 22 Feb 2020, the Aungba Health Zone chief medical doctor was alerted that suspect bubonic plague cases were reported in the Ugunzu-Makangi village of the Aterlembe health area, Djugu territory, Ituri Province, DR Congo. Murine epizootics were also mentioned in the Makangi village. On 23 Feb 2020, the chief medical doctor of the Aungba health Zone (Lat 2 33' 00'' Long 30 30' 00'') was appointed to visit the...
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PRO/AH/EDR> Ebola update (11): Congo DR (NK, IT) cases, summary, vaccine: Ebola -- DR Congo- 16 637 people were vaccinated as of 22 Feb 2020 with the 2nd vaccine Ad26.ZEBOV/MVA-BN-Filo (Johnson & Johnson) in the 2 health areas from Karisimbi to Goma;- Since the start of vaccination on 8 Aug 2018 with the rVSV-ZEBOV vaccine, 297 699 people have been vaccinated.--Communicated by:ProMED-mail[Also see WHO AFRO dashboard at .]- Mon 24 Feb 2020. CMRE (Comite Multisectoriel de la Riposte a la maladie...
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PRO/AH/EDR> COVID-19 update (19): China, global, Italy & Iran. imported cases, WHO: COVID-19 -- ChinaAt 04:00 on [26 Feb 2020], 31 provinces (autonomous regions and municipalities) and the Xinjiang Production and Construction Corps reported 433 new confirmed cases and 29 new deaths (26 in Hubei and 1 in Beijing, Heilongjiang, and Henan). 508 new suspected cases were added. On the same day, 2750 new cases were cured and discharged, and 1823 people who had been in close contact with medical...
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Pinyin Is an Effective Proxy for Early Screening for Mandarin-Speaking Children at Risk of Reading Disorders: Reading disorders (RD) are common and complex neuropsychological conditions associated with decoding printed words and/or reading comprehension. Early identification of children at risk of RD is critical to allow timely interventions before mental suffering and reading impairment take place. Chinese is a unique medium for studying RD because of extra efforts required in reading acquisition...
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Investigating Flow State and Cardiac Pre-ejection Period During Electronic Gaming Machine Use: Flow activities (e.g. sports and gaming) have been associated with positive affect and prolonged engagement. In the gambling field, modern electronic gaming machines (EGMs, including modern slot machines) have drawn concern as a potentially flow-inducing activity that may be associated with gambling-related harms. Current research has heavily relied on self-reported flow, and further insights may be afforded...
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Aging Effects on Phonological and Semantic Priming in the Tip-of-the-Tongue: Evidence From a Two-Step Approach: The mechanism underlying the age difference in spoken word production remains controversial. We used a two-step approach proposed by Gollan and Brown (2006) to investigate the semantic and phonological retrieval deficits when tip-of-the-tongue occurs in young and older adults. Importantly, we controlled the inhibition ability in both older and young groups. In experiment 1 with a people...
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Development of Cynicism in Medical Students: Exploring the Role of Signature Character Strengths and Well-Being: Reports of medical students experiencing burnout-related symptoms (e.g., cynicism) have increased in recent years. Little is known about the developmental process of this phenomenon and its relations with signature character strengths and well-being. The aim of this longitudinal analysis was to explore changes in the level of cynicism of medical students while in preclinical education....
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Music, Rhythm and Trauma: A Critical Interpretive Synthesis of Research Literature: Recent theorizing about the connection between the brain and trauma (Perry, 2009; Porges, 2011; van der Kolk, 2015) has led to a burgeoning of interest in the provision of music-based programs with people who have had adverse experiences. Although there has been critique of the lack of scientific basis of these theories and their implications for practice (McLean, 2016), they remain popular with practitioners who...
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Height After Side: Goalkeepers Detect the Vertical Direction of Association-Football Penalty Kicks From the Ball Trajectory: The present research analyzes the relation between the height of penalty kicks in association football and (a) the probability that goalkeepers stop the ball, (b) the kinematics of the kicker, and (c) the movements of the goalkeeper. We re-analyzed movement registration data that were collected in an experiment (with professional and semi-professional players) that focused...
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Design and Fabrication of Three-Dimensional Printed Scaffolds for Cancer Precision Medicine: Tissue Engineering Part A, Ahead of Print. AbstractThree-dimensional (3D)-engineered scaffolds have been widely investigated as drug delivery systems (DDS) or cancer models with the aim to develop effective cancer therapies. The in vitro and in vivo models developed via 3D printing (3DP) and tissue engineering concepts have significantly contributed to our understanding of cell–cell and cell–extracellular...
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Deaf moths evolved noise-cancelling scales to evade predators: Some species of deaf moths can absorb as much as 85 per cent of the incoming sound energy from predatory bats — who use echolocation to detect them. The findings, published in Royal Society Interface today [26 February], reveal the moths, who are unable to hear the ultrasonic calls of bats, have evolved this clever defensive strategy to help it survive. (Source: University of Bristol news)
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Hearing aids may delay cognitive decline, research finds: (University of Melbourne) Wearing hearing aids may delay cognitive decline in older adults and improve brain function, according to promising new research. University of Melbourne researchers have tested the use of hearing aids in almost 100 adults aged 62-82 years with hearing loss. After 18 months of hearing aid use, researchers found speech perception, self-reported listening disability and quality of life had significantly improved for...
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The Case of the Missing Nose: Congenital Arhinia Case Presentation and Management Recommendations: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objectives:To discuss the presentation and management of infants with arhinia or congenital absence of the nose.Methods:This case report describes an infant with arhinia that was diagnosed prenatally. In addition to a discussion of the case, a review of the literature was completed to define appropriate postnatal work-up and management.Results:The...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,