Effectiveness of a Pulmonary Rehabilitation Program on Persistent Asthma Stratified for SeverityBACKGROUND:Asthma is defined by airway inflammation associated with various respiratory symptoms, and pharmacologic treatment is based on inhaled corticosteroids and bronchodilators. Physical activity, educational training, nutritional support, and psychological counseling are considered part of non-pharmacologic treatment; however, studies so far have investigated the effect of single non-pharmacologic...
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Alcohol-mediated behaviours and the gut-brain axis; with focus on glucagon-like peptide-1.Related ArticlesAlcohol-mediated behaviours and the gut-brain axis; with focus on glucagon-like peptide-1. Brain Res. 2019 Nov 21;:146562 Authors: Elisabet J Abstract The neurochemical mechanisms that regulate development of alcohol use disorder (AUD) are complex, and gut-brain peptides were recently pinpointed as novel modulators. Gut-brain peptides, such as glucagon-like peptide-1 (GLP-1), are well known for...
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Comparison of the structural dynamic and mitochondrial electron-transfer properties of the proapoptotic human cytochrome c variants, G41S, Y48H and A51V.Related ArticlesComparison of the structural dynamic and mitochondrial electron-transfer properties of the proapoptotic human cytochrome c variants, G41S, Y48H and A51V. J Inorg Biochem. 2019 Nov 14;203:110924 Authors: Deacon OM, White RW, Moore GR, Wilson MT, Worrall JAR Abstract Mitochondrial cytochrome c is associated with electron transfer in...
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ScienceDirect Publication: International ImmunopharmacologyIntroducing of an integrated artificial neural network and Chou's pseudo amino acid composition approach for computational epitope-mapping of Crimean-Congo haemorrhagic fever virus antigensPublication date: Available online 24 November 2019Source: International ImmunopharmacologyAuthor(s): Mokhtar Nosrati, Hassan Mohabatkar, Mandana BehbahaniAbstractThis study was aimed to introduce a novel algorithm for determining linear B- and T-cell...
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The Effects of Different Exercise Trainings on Suprahyoid Muscle Activation, Tongue Pressure Force and Dysphagia Limit in Healthy SubjectsAbstract Suprahyoid muscle activation and tongue pressure force play a critical role for swallowing function. In addition, dysphagia limit is one of most important factors indicating swallowing efficiency. The purpose of this study was to compare the effects of 8-week training sessions of three different exercises including chin tuck against resistance (CTAR),...
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Study tracks genomic changes that reinforce darter speciationWhen they share habitat, orangethroat and rainbow darters tend to avoid one another, even though they are closely related and can produce 'hybrid' offspring. A new study offers an analysis of the genomic changes that occur when these fish hybridize, offering insight into the gradual accumulation of incompatible traits that likely drives them to diverge.Evolutionary Biology News -- ScienceDailyMon Nov 25, 2019 19:09Mark above section as...
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Laryngo-Rhino-Otologie,Spätkomplikationen nach Tracheotomie im ambulanten PflegebereichLaryngo-Rhino-OtolDOI: 10.1055/a-1058-0440 Hintergrund Fortschritte der modernen Intensivmedizin haben zu einem drastischen Anstieg der Tracheotomie-Zahlen auf Intensivstationen geführt. Im Gegensatz zur chirurgischen epithelisierten Tracheostomie (ST) entsteht mittels perkutaner Dilatation angelegter Tracheotomie (PDT) ein nur wenig stabiles Stoma. Die Vorteile einer PDT im Vergleich zur ST liegen in dem geringeren...
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Simultaneous multi-signal quantification for highly precise serodiagnosis utilizing a rationally constructed platformNature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13358-0Single channel detection methods often suffer from false positives when analysing biological samples. Here, the authors report on the development of a three-channel detection device for measuring hydrogen sulphide in serum and demonstrate application in an in vivo model.Nature Communications -...
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Update on Facial Skin Rejuvenation TechnologyRecent years have provided multiple modalities being promoted for improvement of facial appearance, including facial rhytid removal or smoothing, facial lesion correction, scar improvement, and general tightening and skin rejuvenation. Evaluation of the effectiveness of these techniques in addition to insightful selection of the appropriate equipment and treatment technology can be challenging to the contemporary facial plastic surgeon. This issue of Facial...
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Latest Results for PsychopharmacologyBinding of the D3-preferring antipsychotic candidate F17464 to dopamine D3 and D2 receptors: a PET study in healthy subjects with [ 11 C]-(+)-PHNOAbstract Rationale F17464, a dopamine D3 receptor antagonist with relatively high D3 selectivity (70 fold vs D2 in vitro), exhibits an antipsychotic profile in preclinical studies, and therapeutic efficacy was demonstrated in a randomized placebo-controlled clinical trial in patients with schizophrenia (Bitter et al....
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International Journal of Environmental Research and Public Health,IJERPH, Vol. 16, Pages 4698: Parent Engagement and Support, Physical Activity, and Academic Performance (PESPAAP): A Proposed Theoretical ModelIJERPH, Vol. 16, Pages 4698: Parent Engagement and Support, Physical Activity, and Academic Performance (PESPAAP): A Proposed Theoretical Model International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16234698 Authors: Ryan D. Burns Yang Bai You Fu Christopher D....
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Psychological impact of working in paediatric intensive care. A UK-wide prevalence studyGareth A L Jones, Gillian A Colville, Padmanabhan Ramnarayan et al. (2019-11-21)10.1136/archdischild-2019-317439Daily life participation in childhood chronic disease: a qualitative studyMerel M Nap-van der Vlist, Marijke C Kars, Emma E Berkelbach van der Sprenkel et al. (2019-11-20)10.1136/archdischild-2019-318062PostScriptWhat does 'PEWing' or 'PEWsing' mean? A new word in paediatricsCatherine Diskin, Rachel...
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Closure of the retroperitoneal space in laparoscopic anterior resection with FLEXDEX™Comment on 'Optimized fistulectomy using the novel FiXcision ® device: a technical feasibility study and evaluation of short term healing rates'The evidence base for pilonidal sinus surgery is the pitsImproving outcomes for the treatment of Anal Squamous Cell Carcinoma and Anal Intraepithelial NeoplasiaNear-infrared fluorescence imaging for sentinel lymph node identification in colon cancer: a prospective single-center...
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Nonpowder Firearm Injuries to Children Treated in Emergency DepartmentsMargaret Jones, Sandhya Kistamgari and Gary A. SmithFrom the American Academy of PediatricsDealing With the Caretaker Whose Judgment Is Impaired by Alcohol or Drugs: Legal and Ethical ConsiderationsSteven A. Bondi, James Scibilia and COMMITTEE ON MEDICAL LIABILITY AND RISK MANAGEMENTPerinatal Palliative CareAluminum Effects in Infants and ChildrenMark R. Corkins and COMMITTEE ON NUTRITION
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Association between Smoking and 30-Day Outcomes in Otologic SurgeryEmily Kay-Rivest, Marco Mascarella, Maida J. Sewitch, François Cloutier, Tamara MijovicOtolaryngology–Head and Neck SurgeryNov 19, 2019 | OnlineFirstOriginal ResearchAppropriateness of Otic Quinolone Use among Privately Insured US PatientsPhuong T. Tran, Almut G. Winterstein, Xi Wang, Kiyon Rhew, Patrick J. AntonelliOtolaryngology–Head and Neck SurgeryNov 19, 2019 | OnlineFirstOriginal ResearchEpidemiology of Pediatric Tracheostomy...
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Implementation Strategies for Cardiovascular PolypillsMark D. Huffman, MD, MPH; Abdul Salam, PhD; Anushka Patel, MD, PhDAudio Interview: Implementation Strategies for Cardiovascular PolypillsCardiovascular Disease Prevention at a Crossroads: Precision Medicine or Polypill?Michael J. Joyner, MD; Nigel Paneth, MD, MPHAUDIOAudio InterviewImplementation Strategies for Cardiovascular PolypillsTRENDING NOW ON JAMA NETWORK OPENAssessment of Jugular Venous Blood Flow Stasis and Thrombosis During SpaceflightAssessment...
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Otoscopic Clinic,Cavernous Hemangioma of the External Auditory Canal in Patients Older than 60 Years: A Rare Tumor,Junhui Jeong, Yeejeong Kim, Tae Seong Eo, Hyun Seung ChoiEar, Nose & Throat JournalNov 24, 2019 | OnlineFirstPathology ClinicNoninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear FeaturesLester D. R. ThompsonEar, Nose & Throat JournalNov 24, 2019 | OnlineFirstOtherVerrucous Squamous Cell CarcinomaLester D. R. ThompsonEar, Nose & Throat JournalNov 24, 2019 | OnlineFirstPathology...
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Ten Commandments of Safe and Optimum Neck DissectionZeal to HealPost-pneumonectomy Empyema Due to Necrosis and Perforation of a Herniated StomachAbstractPleural complications after pneumonectomy occur not only in the early postoperative period but also several years after surgery. Post-pneumonectomy empyema (PPE) is such a possible complication that must be recognized and adequately treated. Sometimes the management of PPE can be extremely challenging because of an abnormal disease presentation and...
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Emerging antimicrobial resistance and newer tools to address the resistancePardeep Kumar Goyal, Ankita Semwal, Ajay Prakash, Bikash MedhiIndian Journal of Pharmacology 2019 51(5):291-295Nicorandil: A drug with ongoing benefits and different mechanisms in various diseased conditionsLamiaa Ahmed AhmedIndian Journal of Pharmacology 2019 51(5):296-301Nicorandil is a well-known antianginal agent, which has been recommended as one of the second-line treatments for chronic stable angina as justified by...
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Facial Skin Rejuvenation Technology,FACIAL PLASTIC SURGERY CLINICS OF NORTH AMERICAPrefaceHaving beautiful skin has been a constant desire through the ages, and the history of skin improvement, including cosmetics, dates to ancient Egypt nearly 6000 years ago.1 My interest in skin care started with my residency training at Baylor College of Medicine. At that time, most commercial skin-care improvement products existed in cosmetics, and not much was available for prescription skin-care and medical...
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Clinical and Experimental DermatologyEarly ViewOnline Version of Record before inclusion in an issueConcise reportsThe spectrum of staphylococcal scalded skin syndrome: a case series in childrenD. R. Mazori, A. Leonard, J. B. Alexander, S. A. GlickVersion of Record online: 22 November 2019Viewpoints in dermatologyCorrespondenceMycobacterium chelonae infection mimicking Demodex folliculitisM. Gibson, C. Theocharous, K. Tran, D. F. Murrell, B. S. DanielVersion of Record online: 21 November 2019Original...
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Conventional X-ray as an additional tool in the analysis of fatal neck traumaMedico-legal considerations for Morel-Lavallée lesionsAbstractThe Morel-Lavallée lesion is an infrequent traumatic lesion that the forensic physician may need to evaluate during examination of a victim. Using a review of the literature and an illustrative case, the objective of this paper is to discuss the medico-legal issues (accountability, functional recovery and healing times, and aftermath) associated with Morel-Lavallée...
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High heavy metal load does not inhibit nitrogen fixation in moss-cyanobacteria associationsAbstractNitrogen (N2) fixation by moss-associated cyanobacteria is one of the main sources of new N input in pristine ecosystems such as boreal forests and arctic tundra. Given the non-vascular physiology of mosses, they are especially sensitive to e.g. increased N input and heavy metal deposition. While the effects of increased N input on moss-associated N2 fixation has been comprehensively assessed, hardly...
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detection of Cryptosporidium and Giardia in the slaughterhouse, sewage and river waters of the Qinghai Tibetan plateau area (QTPA), ChinaThe authors of this article would like to state that C. environmental is not a species, but rather a group of un-identified Cryptosporidium isolates from the environment. It is referred to in the literature as Cryptosporidium environmental sequence and not as a species.Chrysomya bezziana : a case report in a dog from Southern China and review of the Chinese literatureAbstractChrysomya...
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Engaging Young Men as Community Health Leaders in an STI and Intimate Partner Violence Prevention Trial in Dar es Salaam, TanzaniaAbstractBackgroundThis article presents lessons learned from a microfinance and health intervention for young men designed to prevent sexually transmitted infections (STI) and intimate partner violence (IPV) in Dar es Salaam, Tanzania. We describe the different strategies we used to identify and train young men to become change agents within their social networks.DescriptionA...
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Biomechanical and microstructural characterisation of the porcine stomach wall: Location- and layer-dependent investigationsPublication date: Available online 22 November 2019Source: Acta BiomaterialiaAuthor(s): Melanie Bauer, Enrique Morales-Orcajo, Lisa Klemm, Robert Seydewitz, Victoria Fiebach, Tobias Siebert, Markus BölAbstractThe mechanical properties of the stomach wall help to explain its function of storing, mixing, and emptying in health and disease. However, much remains unknown about its...
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Efficacy of All- Trans -Retinoic Acid in High-Risk Acute Myeloid Leukemia with Overexpression of EVI1AbstractIntroductionEVI1 (MECOM)-positive acute myeloid leukemia (AML) cells have shown in vitro sensitivity to all-trans-retinoic acid (ATRA) by inducing differentiation, cell death, and decreased leukemic engraftment.MethodsIn this pilot study, we investigated the response to ATRA in 13 high-risk AML patients with overexpression of EVI1.ResultsSeven of the 13 patients (53.8%) achieved complete remission...
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Structural and Functional Organization and Evolution of the WD40 Genes Involved in the Regulation of Flavonoid Biosynthesis in the Triticeae TribeAbstractFlavonoid biosynthesis in plants is regulated by a specific MBW protein complex, which is formed by the interaction of the R2R3-Myb, bHLH, and WD40 transcription factors. The genomes of the representatives of the Triticeae tribe are characterized by the presence of orthologous and homeologous copies of the flavonoid biosynthesis regulatory genes....
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Thoracic radiotherapy for extensive-stage small-cell lung cancer: what is the optimal dose and timing?Guler Yavas, Cagdas YavasPages 251-258Original ResearchChallenges in the re-irradiation of locally advanced head and neck cancers: outcomes and toxicitiesChristina Phuong, Anthony Pham, Sukhjeet S. Batth…Pages 259-266Original ResearchPatterns of utilization and comparative efficacy of altered fractionation and concurrent chemoradiation for treatment for T2N0M0 glottic carcinomaAnesa Ahamad, Sharon...
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Effectiveness and Patient Satisfaction with Budesonide/Formoterol Easyhaler ® Among Patients with Asthma or COPD Switching from Previous Treatment: a Real-World Study of Patient-Reported OutcomesAbstractIntroductionPersistent symptoms, poor disease control, and reduced quality of life (QoL) are common in patients with asthma and chronic obstructive pulmonary disease (COPD). Current therapies are only partially effective and inhaler misuse contributes to insufficient disease control and poor outcomes....
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Chika Watanabe: Becoming One: Religion, Development, and Environmentalism in a Japanese NGO in MyanmarAmanda Lashway, Christian Vannier and Steven Sampson (eds.): Culture of Doing Good: Anthropologists and NGOsTerry Gibson: Making Aid Agencies Work: Reconnecting INGOs with the People They ServeHumanitarian Organizations in International Disaster Relief: Understanding the Linkage Between Donors and Recipient CountriesAbstractThis study explores how humanitarian organizations (HOs) link donors and...
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Improvement of the robustness to set up error by a virtual bolus in total scalp irradiation with Helical TomoTherapyAbstractIntensity-modulated radiation therapy has recently been used for total scalp irradiation. In inverse planning, the treatment planning system increases the fluence of tangential beam near the skin surface to counter the build-up region. Consequently, the dose to the skin surface increases even with small setup errors. Replacing the electron density of the surrounding air of some...
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Explaining the Illusion of Asymmetric InsightAbstractPeople tend to think that they know others better than others know them (Pronin et al. in Journal of Personality and Social Psychology 81: 639–656, 2001). This phenomenon is known as the "illusion of asymmetric insight." While the illusion has been well documented by a series of recent experiments, less has been done to explain it. In this paper, we argue that extant explanations are inadequate because they either get the explanatory direction...
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Effects of funding mechanisms on participation in multilateral environmental agreementsIn the original publication of the article, there were few mistakes in the text, tables and figure. The corrected text has been presented with this correction.Farewell editorialAn economic analysis of international environmental rightsAbstractThis article offers a descriptive and normative economic analysis of international environmental rights. States, sovereignty, international negotiations, and international...
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Intra-articular injection of hUC-MSCs expressing miR-140-5p induces cartilage self-repairing in the rat osteoarthritisAbstractIntroductionCurrently, osteoarthritis (OA) receives global increasing attention because it associates severe joint pain and serious disability. Stem cells intra-articular injection therapy showed a potential therapeutic superiority to reduce OA development and to improve treating outputs. However, the long-term effect of stem cells intra-articular injection on the cartilage...
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Thucydides's Trap "when one great power threatens to displace another, war is almost always the result".
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Graham Allison, Destined for War: Can America and China Escape Thucydides's Trap?M. Taylor Fravel, Active Defense: China's Military Strategy since 1949Karen Eggleston, Jean C. Oi, and Yiming Wang, eds., Challenges in the Process of China's UrbanizationSuisheng Zhao, ed., Debating Regime Legitimacy in Contemporary China: Popular Protests and Regime PerformancesChen, Ling. Manipulating Globalization: The Influence of Bureaucrats on Business in ChinaXiaoyu Pu, ed., Rebranding China: Contested Status...
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Naive T cells can be primed for tissue residencyAlexandra Flemmingpp718 - 719 | doi:10.1038/s41577-019-0239-zThis study sheds light onto the processes by which naive T cells are preconditioned for tissue residency.PDFEffects of stroke beyond the brainConnie H. Y. Wongp719 | doi:10.1038/s41577-019-0234-4Connie Wong describes a 2003 paper by Andreas Meisel and colleagues linking post-stroke systemic immunosuppression to effects of the sympathetic nervous system on immune cells.PDFIL-17: an immune mnemonicYvonne...
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Long non-coding RNA GAS5 acts as proliferation "brakes" in CD133+ cells responsible for tumor recurrenceNikita S. Sharma, Prisca Gnamlin, Brittany Durden, Vineet K. Gupta, Kousik Kesh et al.Oncogenesis 2019 8: 10.1038/s41389-019-0177-4Abstract | Full TextMT1G serves as a tumor suppressor in hepatocellular carcinoma by interacting with p53Yingchao Wang, Gaoxiong Wang, Xionghong Tan, Kun Ke, Bixing Zhao et al.Oncogenesis 2019 8: 10.1038/s41389-019-0176-5Abstract | Full TextEpigenetic regulation of...
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Extubation Parameters and Postoperative Sore Throat,Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement on Perioperative Smoking CessationSmokers are at increased risk for surgical complications. Despite the known benefits of smoking cessation, many perioperative health care providers do not routinely provide smoking cessation interventions. The variation in delivery of perioperative smoking cessation interventions may be due to limited high-level evidence for...
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Anticipating a Banner Year for NursingWhat do you want to accomplish?Milk and Molasses EnemasNo abstract availableMilk and Molasses EnemasNo abstract availableDelirium in ICU PatientsNo abstract availableNursing Theory in Hospital Models of CareNo abstract availableThe Cannabis ConundrumUnderstanding a popular but still investigational medicinal plant.States Take On High Drug CostsNew laws aim to monitor and restrain price hikes.NewsCAP: Clinical trial shows N95 respirator and medical mask provide...
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Collaboration to prevent an influenza pandemic,Empowering DNP students through mentorship in NP organizationsNo abstract availableElectronic nicotine delivery systems, adolescent use, and nicotine addictionNo abstract availableLowering the cost of prescription drugsNo abstract availableEradicating hepatitis C virus: The APRN's roleAbstract: Chronic hepatitis C virus (HCV) infection is a leading cause of liver disease. The World Health Organization has called for the global elimination of HCV by 2030....
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Effect of Uric Acid Control on Serum CreatinineObjective Hyperuricemia has been epidemiologically associated with multiple comorbidities including chronic renal failure and cardiovascular disease. Cause and effect are difficult to address, given comorbidities associated with and prevalence of metabolic syndrome. One impediment to achieving serum uric acid (sUa) levels less than or equal to 6.0 mg/DL is the concept that allopurinol might be nephrotoxic. We examined the relation of sUa less than or...
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Correlation of Cardiovascular Risk Factors and Biomarkers With Platelet Reactivity in Coronary Artery DiseaseBackground: Low response to aspirin, aspirin resistance, and high platelet reactivity on aspirin treatment are similar names for lack of response to block arachidonic acid–induced aggregation with aspirin therapy and have an important role in the evolution of coronary artery disease (CAD) with thromboembolic events. Study Question: Was to evaluate the correlation between cardiovascular risk...
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The Benefit of Influenza Vaccines: Beyond Prevention of Clinical InfectionNo abstract availableHighlights of Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of AmericaAsymptomatic bacteriuria is a common cause of unnecessary antimicrobial use. The Infectious Diseases Society of America has published an update of the clinical practice guideline for the management of asymptomatic bacteriuria. The guideline provides recommendations...
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Short-Term Clinical and Quality Outcomes Have Inconsistent Changes From a Quality Improvement Initiative to Increase Access to Physical Therapy in the Cardiovascular and Surgical ICUObjectives: Studies of mobility during critical illness have mostly examined transitions from immobility (passive activities) or limited mobility to active "early mobility." Design: Observational analysis of a quality improvement initiative. Setting: Two ICUs (surgical ICU, cardiovascular ICU) at a tertiary academic medical...
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Activation of HMGB1 – TLR4 pathway and Inflammasome contribute to enhanced inflammatory response in extended criteria and kidneys with KDPI ≥ 85%Background. Metrics for evaluating "low-quality" kidneys have failed to predict outcomes or reduce the kidney refusal and discard rates. Kidneys from extended-criteria donors (ECDs) and kidneys with ≥85% kidney donor profile indexes (KDPI) might have different sensitivities to the proinflammatory milieu generated by brain death. We aimed to identify gene...
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Peptidylarginine Deiminase 2 Knockout Improves Survival in Hemorrhagic ShockBackground: The peptidylarginine deiminase (PAD) family converts arginine into citrulline through protein citrullination. PAD2 and PAD4 inhibitors can improve survival in hemorrhagic shock (HS). However, the impact of isoform specific PAD inhibition in improving survival has not been studied. In this study, we utilize selective Pad2−/− knockout (KO) mice to elucidate loss of function of PAD2 leads to pro-survival effect in...
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Interactions between analgesic drug therapy and mindfulness-based interventions for chronic pain in adults: protocol for a systematic scoping reviewIntroduction: Most current chronic pain treatment strategies have limitations in effectiveness and tolerability, and accumulating evidence points to the added benefits of rational combinations of different therapies. However, most published clinical trials of treatment combinations have involved combinations of 2 drugs, whereas very little research has...
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Selective afferent renal denervation mitigates renal and splanchnic sympathetic nerve overactivity and renal function in chronic kidney disease-induced hypertensionBackground: Clinical and experimental evidence have shown that renal denervation, by removing both the sympathetic and afferent nerves, improves arterial hypertension and renal function in chronic kidney disease (CKD). Given the key role of renal sympathetic innervation in maintaining sodium and water homeostasis, studies have indicated...
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Promoting Patient Utilization of Outpatient Cardiac Rehabilitation: A JOINT INTERNATIONAL COUNCIL AND CANADIAN ASSOCIATION OF CARDIOVASCULAR PREVENTION AND REHABILITATION POSITION STATEMENTPurpose: Cardiac rehabilitation (CR) is a recommendation in international clinical practice guidelines given its benefits; however, use is suboptimal. The purpose of this position statement was to translate evidence on interventions that increase CR enrollment and adherence into implementable recommendations. Methods:...
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Surgical Management of Complex Syndromic Craniosynostosis: Experience With a Rare Genetic VariantPatients with syndromic craniosynostosis (CS) can present with both intracranial and extracranial manifestations. Extracranial features include proptosis, exorbitism, and midface hypoplasia. Intracranial manifestations can include elevated intracranial pressure (ICP), brainstem compression, foramen magnum stenosis or jugular foramen hypoplasia with resultant venous hypertension and anomalous drainage....
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Multimodality imaging approach to paradoxical embolism: a cauliflower mass on the Eustachian valveNo abstract availableEchocardiographic outcomes from seven randomized trials of transcatheter versus surgical aortic valve replacementAims We performed meta-analyses of echocardiographic outcomes, including postprocedural aortic valve area (AVA), aortic valve mean pressure gradient (MPG), and paravalvular aortic regurgitation (PAR), exclusively from all currently available randomized controlled trials...
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The effect of rolling walker use on interpretation of Timed Up and Go test scores: a preliminary studyStudies have shown that the type of assistive device used during the Timed Up and Go test impacts the time it takes to complete the test. This study examines the impact of the use of a rolling walker within individuals on Timed Up and Go scores and assessment of fall risk. The Berg Balance Scale, Timed Up and Go, and linear gait speed were used to measure balance and fall risk on 13 older adults...
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The effect of pre-procedural sublingual nifedipine on radial artery diameterObjective This study aimed to investigate the effect of nifedipine on radial artery (RA) relaxation before puncture for coronary intervention. Methods In all, 120 patients were randomly assigned to nifedipine or control group. The diameter, resistance index (RI), and peak systolic velocity (PSV) of the RA were observed at 5, 15, and 30 min after nifedipine administration by a Doppler ultrasound examination. Results The greatest...
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Techniques to monitor respiratory drive and inspiratory effortPurpose of review There is increased awareness that derangements of respiratory drive and inspiratory effort are frequent and can result in lung and diaphragm injury together with dyspnea and sleep disturbances. This review aims to describe available techniques to monitor drive and effort. Recent findings Measuring drive and effort is necessary to quantify risk and implement strategies to minimize lung and the diaphragm injury by modifying...
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Single-Cell Functional Proteomics Accelerates Immunotherapy Development, FREE DOWNLOADIntroduction to Cell Therapy: CAR-T therapies have transformed ImmunotherapyCAR-T therapies have quickly shifted the direction of treatments for aggressive diseases, such as blood cancers, where previous treatments were limited. There are currently over 1000 cell and gene therapy trials and two approved cell therapies, Axicabtagene ciloleucel and Tisagenlecleucel, but determining cellular fitness is still a top...
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Pharmacy, Vol. 7, Pages 158: Impact of Pharmacist Involvement on Telehealth Transitional Care Management (TCM) for High Medication Risk PatientsPharmacy, Vol. 7, Pages 158: Impact of Pharmacist Involvement on Telehealth Transitional Care Management (TCM) for High Medication Risk Patients Pharmacy doi: 10.3390/pharmacy7040158 Authors: Jessica Cole Nick Wilkins Maeghan Moss Danny Fu Paige Carson Linda Xiong This pilot study sought to evaluate the impact of pharmacist involvement in the preexisting...
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JoF, Vol. 5, Pages 110: The XVIII Congress of European Mycologists: Conference ReportJoF, Vol. 5, Pages 110: The XVIII Congress of European Mycologists: Conference Report Journal of Fungi doi: 10.3390/jof5040110 Authors: Julia Pawłowska Magdalena Frąc Izabela Kałucka Małgorzata Ruszkiewicz-Michalska Sylwia Różalska Marta Wrzosek The 18th Congress of European Mycologists took place from 16 to 21 September 2019 in Warsaw and Białowieża, Poland (Figure 1) [...]Journal of FungiMon Nov 25, 2019 02:00Mark...
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International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 5933: The Role of EjSVPs in Flower Initiation in Eriobotrya japonicaIJMS, Vol. 20, Pages 5933: The Role of EjSVPs in Flower Initiation in Eriobotrya japonica International Journal of Molecular Sciences doi: 10.3390/ijms20235933 Authors: Yuanyuan Jiang Jiangrong Peng Zhike Zhang Shoukai Lin Shunquan Lin Xianghui Yang Flowering plants have evolved different flowering habits to sustain long-term reproduction. Most woody trees experience...
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International Journal of Environmental Research and Public Health , IJERPH, Vol. 16, Pages 4697: Depressive Symptoms, Lack of Physical Activity, and Their Combination Towards Health Care Utilisation FrequencyIJERPH, Vol. 16, Pages 4697: Depressive Symptoms, Lack of Physical Activity, and Their Combination Towards Health Care Utilisation Frequency International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16234697 Authors: Sandra Haider Igor Grabovac Anita Rieder Thomas...
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Antioxidants, Vol. 8, Pages 586: Saffron Processing Wastes as a Bioresource of High-Value Added Compounds: Development of a Green Extraction Process for Polyphenol Recovery Using a Natural Deep Eutectic SolventAntioxidants, Vol. 8, Pages 586: Saffron Processing Wastes as a Bioresource of High-Value Added Compounds: Development of a Green Extraction Process for Polyphenol Recovery Using a Natural Deep Eutectic Solvent Antioxidants doi: 10.3390/antiox8120586 Authors: Achillia Lakka Spyros Grigorakis...
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Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?Purpose of review The aims of this review are to discuss the impact of extracorporeal membrane oxygenation (ECMO) on antibiotic pharmacokinetics and how this phenomenon may influence antibiotic dosing requirements in critically ill adult ECMO patients. Recent findings The body of literature describing antibiotic pharmacokinetic and dosing requirements during ECMO support in critically adult patients is currently...
Mon Nov 25, 2019 16:49
Conditioned Pain Modulation in Chronic Low Back Pain: A Systematic Review of LiteratureObjective: The objective of the review is to determine whether conditioned pain modulation (CPM) is impaired in adults with chronic low back pain when compared to pain-free individuals. Methods: First a systematic search of the literature was undertaken using the databases: MEDLINE, Scopus, CINAHL and Web of Science. Second, the citations of included studies were reviewed for additional studies. Observational,...
Mon Nov 25, 2019 16:46
Spatiotemporal Dynamics of Immune Cells in Early Left Venticular Remodeling after Acute Myocardial Infarction in MiceMyocardial infarction (MI) remains a leading cause of morbidity and death. Insufficient delivery of oxygen to the myocardium sets into play a complicated process of repair that involves the temporal recruitment of different immune cells so as to remove debris and necrotic cells expeditiously and form effective scar tissue. Clearly defined and overlapping phases have been identified...
Mon Nov 25, 2019 16:46
Functional Mitral Regurgitation in Heart Failure. Erratum.No abstract availableAspirin for the Primary Prevention of Cardiovascular Disease: A Review of the Literature and Considerations for Clinical PracticeCardiovascular disease is the leading cause of death globally, and deaths due to coronary heart disease or stroke account for over half of all cardiovascular deaths in the United States. While many important advances have been made in the treatment and secondary prevention of atherosclerotic...
Mon Nov 25, 2019 16:46
Comparison between blood pressure readings using a mercury versus an aneroid sphygmomanometerObjective For more than a century since its introduction, mercury sphygmomanometer (HgS) had been the mainstay for office measurement of blood pressure (BP). In light of the environmental and health hazards associated with mercury, there is a need to replace it with mercury-free alternatives all over the world. We aimed to validate the widely used aneroid sphygmomanometer (AnS) by comparing its BP readings...
Mon Nov 25, 2019 16:45
Biosimilars and Novel InsulinsBackground: Insulin therapy is the mainstay of treatment for type 1 diabetes and may be necessary in type 2 diabetes. Current insulin analogues present a more physiological profile, are effective, and with less risk of hypoglycemia, but they are expensive. Biosimilar insulins should offer the advantages of insulin analogues at reduced costs. In addition, current rapid-acting insulin analogues are not fast enough to control excessive postprandial glucose excursions in...
Mon Nov 25, 2019 16:45
Effectiveness of hydrotherapy on balance and paretic knee strength in patients with stroke: A systematic review and meta-analysis of randomized controlled trialsObjective To compare the effects of hydrotherapy and land-based conventional therapy (CT) on postural balance and knee strength in stroke patients. Designs A comprehensive search was done via databases (PubMed, EMBASE, and Web of Science) until April, 12th, 2019 to select randomized controlled trials. The methodological quality was assessed...
Mon Nov 25, 2019 16:45
Purification and characterization of a thrombin-like enzyme isolated from Vipera lebetina venom: its interaction with platelet receptorSnake venoms contain various molecules that can be used as tools in the diagnosis and in the treatment of hemostatic disorders. This study reports the isolation and functional characterization of a new thrombin-like enzyme and its role in the modulation of platelet aggregation and coagulation. The molecule was purified by gel filtration, anion exchange chromatography...
Mon Nov 25, 2019 16:44
From the realms of the depths of neurosurgeryAhmed AnsariAsian Journal of Neurosurgery 2019 14(4):1057-1057Flow diversion for the treatment of petrous internal carotid artery aneurysmsMichael George Zaki Ghali, Mandy BinningAsian Journal of Neurosurgery 2019 14(4):1058-1062Petrous internal carotid artery (ICA) aneurysms are rare and pose a unique management dilemma. They are most commonly fusiform. They are difficult to treat surgically and typically not amenable to selective aneurysmal obliteration....
Mon Nov 25, 2019 16:44
His-purkinje conduction system pacing: State of the artKeping Chen, Shu ZhangInternational Journal of Heart Rhythm 2019 4(1):1-3Radiotherapy and devices in cancer patients: What is new in clinical practice?Fabiana Lucà, Iris Parrini, Laura Cipolletta, Stefania Di Fusco, Carmelo Massimiliano Rao, Annamaria Iorio, Andrea Pozzi, Sandro Gelsomino, Domenico Gabrielli, Nadia Ingianni, Massimo Zecchin, Michele Massimo GuliziaInternational Journal of Heart Rhythm 2019 4(1):4-13There has been a significant...
Mon Nov 25, 2019 16:42
Urinary neutrophil gelatinase-associated lipocalin as a clinical biomarker in patients with diabetic nephropathy in Beni-Suef Governorate, EgyptHeba H El Demellawy, Mohammed A El Feki, Hesham H Eissa, Mohamed S Tawfik, Dina F ElessawiJournal of The Egyptian Society of Nephrology and Transplantation 2019 19(4):101-108Aim To demonstrate the importance of the marker of tubulointerstitial damage, urinary neutrophil gelatinase-associated lipocalin (uNGAL), in the follow-up of the progression of chronic...
Mon Nov 25, 2019 16:42
Urinary neutrophil gelatinase-associated lipocalin as a clinical biomarker in patients with diabetic nephropathy in Beni-Suef Governorate, EgyptHeba H El Demellawy, Mohammed A El Feki, Hesham H Eissa, Mohamed S Tawfik, Dina F ElessawiJournal of The Egyptian Society of Nephrology and Transplantation 2019 19(4):101-108Aim To demonstrate the importance of the marker of tubulointerstitial damage, urinary neutrophil gelatinase-associated lipocalin (uNGAL), in the follow-up of the progression of chronic...
Mon Nov 25, 2019 16:39
Urinary neutrophil gelatinase-associated lipocalin as a clinical biomarker in patients with diabetic nephropathy in Beni-Suef Governorate, EgyptHeba H El Demellawy, Mohammed A El Feki, Hesham H Eissa, Mohamed S Tawfik, Dina F ElessawiJournal of The Egyptian Society of Nephrology and Transplantation 2019 19(4):101-108Aim To demonstrate the importance of the marker of tubulointerstitial damage, urinary neutrophil gelatinase-associated lipocalin (uNGAL), in the follow-up of the progression of chronic...
Mon Nov 25, 2019 16:36
National HIV testing and diagnosis coverage in sub-Saharan Africa: a new modeling tool for estimating the "first 90" from program and survey dataObjective: HIV testing services (HTS) are a crucial component of national HIV responses. Learning one's HIV diagnosis is the entry point to accessing life-saving antiretroviral treatment and care. Recognizing the critical role of HTS, the Joint United Nations Programme on HIV/AIDS (UNAIDS) launched the 90-90-90 targets stipulating that by 2020, 90% of people...
Mon Nov 25, 2019 16:36
A Randomized Trial of Continuous Versus Intermittent Skin-to-Skin Contact After Premature Birth and the Effects on Mother–Infant InteractionBackground: Premature birth affects opportunities for interaction between infants and mothers. Skin-to-skin contact (SSC) is standard care in neonatal care but has not been sufficiently studied regarding the effects on interaction between preterm infant and mothers. Purpose: The purpose of this study was to compare interaction between preterm infants and their...
Mon Nov 25, 2019 16:35
Role of triphasic computed tomography in prediction of response to transcatheter arterial chemoembolization in unresectable hepatocellular carcinoma patientsAhmed A.E Hassan Desoky, Mohammed K Omar, Hala M MaghrabyJournal of Medicine in Scientific Research 2019 2(3):181-184Background The initial approach in the management of hepatocellular carcinoma (HCC) is to determine if either surgical resection or liver transplantation is feasible. Unfortunately, more than three-quarters of the patients are...
Mon Nov 25, 2019 16:34
Safer dissection of spinal accessory nerve from sternocleidomastoid muscle during neck dissectionAkhlak Hussain, Ashish Singhal, Nida Siddiquee, Bimlesh ThakurAnnals of Indian Academy of Otorhinolaryngology Head and Neck Surgery 2019 3(2):55-57Background: The spinal accessory nerve (SAN) may damage during its dissection from the sternocleidomastoid (SCM) muscle during modified neck dissection type II due to their intimate relation. Routinely, it is dissected from the anterior aspect of the SCM. The...
Mon Nov 25, 2019 16:33
Free-living Evaluation of Laboratory-based Activity Classifiers in PreschoolersMachine learning (ML) classification models for accelerometer data are a potentially more accurate method to measure physical activity in young children than traditional cut-point methods. However, existing algorithms have been trained on laboratory-based activity trials and their performance has not been investigated under free living conditions. Purpose To evaluate the accuracy of laboratory trained hip and wrist Random...
Mon Nov 25, 2019 16:31
The prevalence of different Kennedy's classifications and their relationship with age, gender, and location of the edentulous arches in PalestineShockry Mustafa, Naji Ziad ArandiInternational Journal of Preventive and Clinical Dental Research 2019 6(3):53-55Aim and Objectives:In West Bank, Palestine, there are no studies that have investigated the prevalence of different Kennedy's classifications and their relationship with age, gender, and location of the edentulous arches. Materials and Methods:...
Mon Nov 25, 2019 16:30
Comparative assessment of left ventricular function after coronary artery bypass grafting and percutaneous coronary intervention to LAD by speckle tracking echocardiography studyMahmoud S Abd El Moneum, Eman Saeed Elkeshk, Khaled Emad El-Din El-Rabbat, Adem M AhmedInternational Journal of the Cardiovascular Academy 2019 5(4):109-115Background: Speckle-tracking echocardiography (STE) is a noninvasive imaging technique that analyzes global and regional myocardial function. Aims: This study aims to...
Mon Nov 25, 2019 16:30
Optimal sidescan sonar and subbottom profiler surveying of ancient wrecks: The 'Fiskardo' wreck, Kefallinia Island, Ionian SeaPublication date: January 2020Source: Journal of Archaeological Science, Volume 113Author(s): George Ferentinos, Elias Fakiris, Dimitrios Christodoulou, Maria Geraga, Xenophontas Dimas, Nikos Georgiou, Stavroula Kordella, George Papatheodorou, Michalis Prevenios, Makis SotiropoulosAbstractMarine geophysical data collected during an underwater natural and cultural heritage...
Mon Nov 25, 2019 16:29
The depressed heartSeth W Perry, Julio Licinio, Ma-Li WongHeart and Mind 2019 3(2):35-46Our appreciation and understanding of the interrelationships between disrupted metabolic function and depression have increased significantly over the last few decades. This review focuses still more specifically on the intersections between cardiovascular disease (CVD) and major depressive disorder (MDD). General pathophysiological mechanisms implicated in both diseases include inflammation, cytokine and hypothalamic–pituitary–adrenal...
Mon Nov 25, 2019 16:28
Human immunodeficiency virus self-testing in adolescents living in Sub-Saharan Africa: An advocacySerge Tonen-Wolyec, François-Xavier Mbopi-Kéou, Donato Koyalta, Mounir Filali, Salomon Batina-Agasa, Laurent BélecNigerian Medical Journal 2019 60(4):165-168Acquired immune deficiency syndrome (AIDS) has become the leading cause of death among adolescents (aged 10–19) in sub-Saharan Africa. Less than 20% of African adolescents know their human immunodeficiency virus (HIV) status, whereas HIV testing...
Mon Nov 25, 2019 16:28
Abstracts of the Second Conference of the Arab Association of Genetic Research (AAGR)Middle East Journal of Medical Genetics 2019 8(1):1-27Prenatal counseling and diagnosis of Gaucher disease in Egypt: an 18-year experienceAhmed L Aboulnasr, Ekram M FateenMiddle East Journal of Medical Genetics 2019 8(1):28-32Objective To provide prenatal counseling (PC) and prenatal diagnosis (PD) of Gaucher disease in pregnant women with previous affected sibling (s). Patients and methods PC was done in 154 pregnancies...
Mon Nov 25, 2019 16:28
Knowledge, attitude and practice on uses of plastic products, their disposal and environmental pollution: A study among school-going adolescentsNajnin Khanam, Vasant Wagh, Abhay M Gaidhane, Syyed Zahiruddin QuaziJournal of Datta Meghe Institute of Medical Sciences University 2019 14(2):57-60Background: Toxic gases and carcinogens released from manufacturing and burning of plastics cause environmental pollution. Aims and Objectives: The objectives of this study are to study the knowledge, attitude,...
Mon Nov 25, 2019 16:27
Impact of Long‐Wavelength Ultraviolet A1 and Visible Light on Light‐Skinned IndividualsIndermeet Kohli, Raheel Zubair, Alexis B. Lyons, Amanda F. Nahhas, Taylor L. Braunberger, Mohsen Mokhtari, Eduardo Ruvolo, Henry W. Lim, Iltefat H. HamzaviPages: 1285-1287 | First Published: 25 July 2019 Solar radiation is known to be a major contributor to the development of skin cancer. Most sunscreen formulations, including those with broad spectrum, offer minimal protection in long wavelength ultraviolet A1...
Mon Nov 25, 2019 16:27
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,Antibiotics, Vol. 8, Pages 234: Development of a Novel Pharmaceutical Formula of Nanoparticle Lipid Carriers of Gentamicin/α-Tocopherol and In Vivo Assessment of the Antioxidant Protective Effect of α-Tocopherol in Gentamicin-Induced NephrotoxicityAntibiotics, Vol. 8, Pages 234: Development of a Novel Pharmaceutical Formula of Nanoparticle Lipid Carriers of Gentamicin/α-Tocopherol...
Mon Nov 25, 2019 09:55
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,