Antioxidants, Vol. 8, Pages 580: Effect of Marine Bacteria and Ulvan on the Activity of Antioxidant Defense Enzymes and the Bio-Protection of Papaya Fruit against Colletotrichum gloeosporioidesAntioxidants, Vol. 8, Pages 580: Effect of Marine Bacteria and Ulvan on the Activity of Antioxidant Defense Enzymes and the Bio-Protection of Papaya Fruit against Colletotrichum gloeosporioides Antioxidants doi: 10.3390/antiox8120580 Authors: Roberto G. Chiquito-Contreras Bernardo Murillo-Amador Saul Carmona-Hernandez...
Oncology, ZnO nanocrystals shuttled by extracellular vesicles as effective Trojan nano-horses against cancer cells.Related ArticlesZnO nanocrystals shuttled by extracellular vesicles as effective Trojan nano-horses against cancer cells. Nanomedicine (Lond). 2019 Nov 21;: Authors: Dumontel B, Susa F, Limongi T, Canta M, Racca L, Chiodoni A, Garino N, Chiabotto G, Centomo ML, Pignochino Y, Cauda V Abstract Aim: The effective application of nanoparticles in cancer theranostics is jeopardized by their...
pubmed: cell cycle arrest, Actinomycin D-Activated RNase L Promotes H2A.X/H2B-Mediated DNA Damage and Apoptosis in Lung Cancer Cells.Related ArticlesActinomycin D-Activated RNase L Promotes H2A.X/H2B-Mediated DNA Damage and Apoptosis in Lung Cancer Cells. Front Oncol. 2019;9:1086 Authors: Yin H, Jiang Z, Wang S, Zhang P Abstract Background: Chemotherapy is an essential component for comprehensive cancer treatment, while drug resistance usually fails therapy. DNA repair mechanism of cancer cells...
pubmed: "world j surg"[jour] Advanced Modeling to Predict Pneumonia in Combat Trauma Patients.Related ArticlesAdvanced Modeling to Predict Pneumonia in Combat Trauma Patients. World J Surg. 2019 Nov 20;: Authors: Bradley M, Dente C, Khatri V, Schobel S, Lisboa F, Shi A, Hensman H, Kirk A, Buchman TG, Elster E Abstract BACKGROUND: Tools to assist clinicians in predicting pneumonia could lead to a significant decline in morbidity. Therefore, we sought to develop a model in combat trauma patients for...
Nature Communications - SERS discrimination of single DNA bases in single oligonucleotides by electro-plasmonic trappingNature Communications, Published online: 22 November 2019; doi:10.1038/s41467-019-13242-xSensing DNA bases by surface-enhanced Raman spectroscopy (SERS) in plasmonic nanopores has suffered from rapid flow through of molecules. Here, the authors attach DNA molecules to gold nanoparticles which, due to electro-plasmonic trapping, allow for controlled residence times and discrimination...
Larynx,Potential of robotic systems in phonosurgery.Related ArticlesPotential of robotic systems in phonosurgery. Robot Surg. 2019;6:3-8 Authors: Vasan N, Sharum M, Rodney JP Abstract There has been rapid growth in the utilization of robotic surgery in the head and neck. Its utilization in the phonosurgical space has lagged owing to difficulty with access and exposure to the laryngeal site, small working space due to the size of the larynx and the need to work around an endotracheal tube. The goal...
ScienceDirect Publication: Annals of Allergy, Asthma & Immunology, Factors Associated with Reduced Time Lapse of Medication Fills in Uncontrolled Childhood AsthmaPublication date: Available online 22 November 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Arlene M. Butz, Melissa H. Bellin, Tricia Morphew, Mona Tsoukleris, Mary Elizabeth BollingerScienceDirect Publication: Annals of Allergy, Asthma & Immunology11:18Evaluation of antihypertensive therapies in immunotherapy-associated...
Angewandte Chemie International Edition,,Organocatalytic Enantioselective Synthesis of Tetrasubstituted α‐Amino Allenoates by Dearomative γ‐Addition of 2,3‐Disubstituted Indoles to β,γ‐Alkynyl‐α‐imino EstersTetrasubstituted α‐amino allenoates were generated by a chiral phosphoric acid catalyzed dearomative γ‐addition of 2,3‐disubstituted indoles to β,γ‐alkynyl‐α‐imino esters. This method provides access to a series of highly functionalized tetrasubstituted allenes featuring quaternary stereocenters...
Psychopharmacology,Co-expression Network of mRNAs and lncRNAs Regulated by Stress-Linked Behavioral AssaysAbstract Rationale Mood-related behavioral assays, designed typically on rodents' natural aversion to certain threats, are useful in studying the mechanisms of mood and in discovering effective treatments for neuropsychiatric disorders. Objectives Although reasonable attention has been paid to the conducted sequence, few studies address the argument whether...Latest Results for Psychopharmacology02:00Nicotine...
Flapless Immediate Implant Placement and Provisionalization in Periodontal Patients: A Retrospective Consecutive Case‐Series Study of Single Tooth Sites with Dehiscence‐Type Osseous DefectsAbstract Objective To assess the clinical outcomes of flapless, immediate implant placement with simultaneous augmentation of dehiscence defects and immediate provisional restoration. Material and Methods Retrospective evaluation of 40 periodontal patients who received a flapless immediate implant for single tooth...
Computational modelling in source space from scalp EEG to inform presurgical evaluation of epilepsyPublication date: Available online 22 November 2019Source: Clinical NeurophysiologyAuthor(s): Marinho A. Lopes, Leandro Junges, Luke Tait, John R. Terry, Eugenio Abela, Mark P. Richardson, Marc GoodfellowAbstractObjectiveThe effectiveness of intracranial electroencephalography (iEEG) to inform epilepsy surgery depends on where iEEG electrodes are implanted. This decision is informed by noninvasive recording...
Phase II study of S-1 in patients with previously-treated invasive thymoma and thymic carcinoma: North Japan lung cancer study group trial 1203.Related ArticlesPhase II study of S-1 in patients with previously-treated invasive thymoma and thymic carcinoma: North Japan lung cancer study group trial 1203. Lung Cancer. 2019 Oct 18;139:89-93 Authors: Tsukita Y, Inoue A, Sugawara S, Kuyama S, Nakagawa T, Harada D, Tanaka H, Watanabe K, Mori Y, Harada T, Hino T, Fujii M, Ichinose M Abstract OBJECTIVES:...
Early Maladaptive Schemas Are Associated with Increased Suicidal Risk among Individuals with SchizophreniaAbstractEarly maladaptive schemas (EMSs) are a dysfunctional cognitive pattern that can result from maladaptive functioning during childhood. EMSs are broad patterns of memories, emotions, cognitions, and bodily sensations related to the self and others. The aims of this study were to evaluate EMSs among individuals with schizophrenia and to evaluate the relations of EMSs and clinical factors...
Clinical utility of 177Lu‐DOTATATE PRRT in somatostatin receptor‐positive metastatic medullary carcinoma of thyroid patients with assessment of efficacy, survival analysis, prognostic variables, and toxicityAbstract Background The primary aim of this study was to evaluate the therapeutic efficacy and outcome of 177Lu‐DOTATATE peptide receptor radionuclide therapy (PRRT) in somatostatin receptor‐positive metastatic medullary thyroid carcinoma (MTC), including progression‐free survival (PFS) and overall...
Evidence-based treatment of cavernous sinus meningiomaEvidence-based treatment of cavernous sinus meningioma Category: Article Type: Javad HekmatpanahDepartment of Neurosurgery, University of Chicago Medicine, Chicago IL USA.DOI:10.25259/SNI_268_2019Copyright: © 2019 Surgical Neurology International This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others...Surgical neurology internationalFri Nov 22,...
Transcription factors NFIA and NFIB induce cellular differentiation in high-grade astrocytomaAbstract Introduction Malignant astrocytomas are composed of heterogeneous cell populations. Compared to grade IV glioblastoma, low-grade astrocytomas have more differentiated cells and are associated with a better prognosis. Therefore, inducing cellular differentiation to alter the behaviour of high-grade astrocytomas may serve as a therapeutic strategy. The nuclear factor one (NFI) transcription factors...
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLCNew England Journal of Medicine, Ahead of Print.Massachusetts Medical Society: New England Journal of Medicine: Table of ContentsThu Nov 21, 2019 06:05Lateral Knee DislocationFigure 1.The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical PracticeThu Nov 21, 2019 02:00Eastern Equine Encephalitis Virus — Another Emergent Arbovirus in the United StatesHumans have always lived in intimate association...
Microvascular Effects of Pulsed Dye Laser in Combination With OxymetazolineBackground and Objective Oxymetazoline, an α‐1A agonist, is approved by the United States Food and Drug Administration (FDA) for treatment of persistent facial erythema associated with rosacea and induces vasoconstriction by interacting with α receptors. The objective of our study was to study the microvascular effects of oxymetazoline and pulsed dye laser (PDL). Materials and Methods A dorsal window chamber was surgically...
Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial CarcinomaHere, we present a protocol to increase the surgical field of view and reduce the difficulty of total transperitoneal laparoscopic nephroureterectomy surgery by precutting the umbilical ligament before treating the terminal ureter.JoVE: Journal of Visualized ExperimentsFri Nov 22, 2019 21:00Evaluating the Differentiation Capacity of Mouse Prostate...
Pattern of inappropriate antibiotic use among hospitalized patients in Pakistan: a longitudinal surveillance and implicationsThe inappropriate use of antibiotics in hospitals increases resistance, morbidity, and mortality. Little is currently known about appropriate antibiotic use among hospitals in Lahore, the capital city of Pakis...Antimicrobial Resistance and Infection Control - Latest ArticlesThu Nov 21, 2019 02:00Unidirectional animal-to-human transmission of methicillin-resistant Staphylococcus...
Integration of PET-imaging into radiotherapy treatment planning for low-grade meningiomas improves outcomeAbstract Purpose Meningiomas have an excellent survival prognosis, and radiotherapy (RT) is a central component of interdisciplinary treatment. During treatment planning, the definition of the target volume remains challenging using MR and CT imaging alone. This is the first study to analyze the impact of additional PET-imaging on local control (LC) and overall survival (OS) after high-precision...
Healthy Diet Tied to Lower Risk of Hearing Loss,Eating a healthy diet has been associated with lower risk of heart disease, stroke, and many other conditions, and now a new study found it may also reduce the risk of acquired hearing loss (Am J Epidemiol. 2019 Oct 14. pii: kwz223. doi: 10.1093/aje/kwz223. [Epub ahead of print]). Using over 20 years of dietary intake information from the Nurses' Health Study II Conservation of Hearing Study (CHEARS), researchers from Brigham and Women's Hospital investigated...
Redo Tracheostomy: Our Experience, Problems Encountered and How to Overcome Them.Related ArticlesRedo Tracheostomy: Our Experience, Problems Encountered and How to Overcome Them. Indian J Otolaryngol Head Neck Surg. 2019 Dec;71(4):470-473 Authors: Sayoo C, Das AK, Das A, Rahman T, Das RJ, Das K Abstract Tracheostomy is a life-saving procedure done electively or most commonly in emergency basis. In patients with diagnosed case of cancer in upper airway tract they usually require tracheostomy at some...
Revision surgery rates in chronic rhinosinusitis with nasal polyps: meta-analysis of risk factors.Related ArticlesRevision surgery rates in chronic rhinosinusitis with nasal polyps: meta-analysis of risk factors. Int Forum Allergy Rhinol. 2019 Nov 21;: Authors: Loftus CA, Soler ZM, Koochakzadeh S, Desiato VM, Yoo F, Nguyen SA, Schlosser RJ Abstract BACKGROUND: Wide variations in revision endoscopic sinus surgery (ESS) rates for chronic rhinosinusitis with nasal polyposis (CRSwNP) have been reported....
Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability ElementAnalysis of synonymous mutations established that although the primary amino acid sequence remains unchanged, alterations in transcription and translation can result in significant phenotypic consequences. We report the novel observation that a series of nonsynonymous mutations in an unconserved stretch of amino acids found in the yeast multidrug efflux pump Pdr5 increases expression, thus enhancing...
Intra-articular injection of hUC-MSCs expressing miR-140-5p induces cartilage self-repairing in the rat osteoarthritisAbstract Introduction Currently, osteoarthritis (OA) receives global increasing attention because it associates severe joint pain and serious disability. Stem cells intra-articular injection therapy showed a potential therapeutic superiority to reduce OA development and to improve treating outputs. However, the long-term effect of stem cells intra-articular injection on the cartilage...
Success rate 1 year after apical surgery: a retrospective analysisAbstract Purpose The aim of the current study was the retrospective analysis of the outcomes of teeth treated with apical surgery after a 1-year follow-up period. Furthermore, potential factors associated with the success rate were investigated. Methods All patients were treated at the Clinic of Cranio-Maxillofacial and Oral Surgery at the University of Zurich...Oral and Maxillofacial SurgeryFri Nov 22, 2019 02:00Customised, disposable...
Coccydynia relieved by a tarsal tunnel block: a case series,This case series describes, for the first time, to the author's knowledge, a novel treatment for coccydynia. Tarsal tunnel block with lignocaine only brought relief of chronic coccydynia lasting more than 6 mo...Journal of Medical Case Reports - Latest ArticlesThu Nov 21, 2019 02:00Unusual Case of Localized Upper Limbs and Truncal Edema Associated with Fever, Anemia, and Acute Kidney InjuryThe patient is a 75-year-old man who presented with...
Polydatin Exerts an Antitumor Effect Through Regulating miR-382/PD-L1 Axis in Colorectal CancerCancer Biotherapy and Radiopharmaceuticals, Ahead of Print.Cancer Biotherapy & Radiopharmaceuticals - Table of Contents07:10ZEB2-AS1 Accelerates Epithelial/Mesenchymal Transition Through miR-1205/CRKL Pathway in Colorectal CancerCancer Biotherapy and Radiopharmaceuticals, Ahead of Print.Cancer Biotherapy & Radiopharmaceuticals - Table of Contents07:10Intrigue: Phase III study of ripretinib versus...
Characterization of a Halotolerant Fungus from a Marine SpongeIntroduction. Marine sponges have established symbiotic interactions with a large number of microorganisms including fungi. Most of the studies so far have focussed on the characterization of sponge-associated bacteria and archaea with only a few reports on sponge-associated fungi. During the isolation and characterization of bacteria from marine sponges of South Australia, we observed multiple types of fungi. One isolate in particular...
[ASAP] An Integrated Approach for Determining a Protein–Protein Binding Interface in Solution and an Evaluation of Hydrogen–Deuterium Exchange Kinetics for Adjudicating Candidate Docking ModelsAnalytical ChemistryDOI: 10.1021/acs.analchem.9b03879Analytical ChemistryFri Nov 22, 2019 07:00[ASAP] Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large ProteoformsAnalytical ChemistryDOI: 10.1021/acs.analchem.9b03925Analytical ChemistryFri Nov 22, 2019 07:00[ASAP] Visual Simultaneous...
Associations of the BRAF V600E Mutation and PAQR3 Protein Expression with Papillary Thyroid Carcinoma Clinicopathological FeaturesAbstract The BRAFV600E mutation is the most prevalent genetic event in patients with papillary thyroid cancer (PTC). However, no study has investigated the expression of PAQR3 in papillary thyroid tissues in relation to the BRAFV600E mutation and the clinicopathological features of PTC patients. Furthermore, the potential associations of the BRAFV600E mutation, PAQR3 expression...
A novel mutation in NCF2 resulting in very-early-onset colitis and juvenile idiopathic arthritis in a patient with chronic granulomatous diseaseChronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder caused by a defect in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. The disease primarily presents wit...Allergy, Asthma & Clinical Immunology - Latest ArticlesThu Nov 21, 2019 02:00Agreement between self-reported asthma symptoms and exhaled nitric...
Εγκεφαλικό επεισόδιο: Τι αλλάζει για τις γυναίκες συγκριτικά με τους άνδρεςΠερισσότερες πιθανότητες να επιβιώσουν από εγκεφαλικό επεισόδιο, αλλά χειρότερη ποιότητα ζωής μετά από αυτό έχουν οι γυναίκες συγκριτικά με τους άνδρες, σύμφωνα με έρευνα που πραγματοποιήθηκε από επιστήμονες του Ινστιτούτου George και δημοσιεύθηκε στο Neurology. Οι ερευνητές εξέτασαν τις διαφορές ανάμεσα στα δύο φύλα όσον αφορά τη θεραπεία και τις συνέπειες του εγκεφαλικού επεισοδίου. Συνολικά μελέτησαν 19.652 άτομα που συμμετείχαν...
Plants, Vol. 8, Pages 536: Comparative Analysis of the YABBY Gene Family of Bienertia sinuspersici, a Single-Cell C4 PlantPlants, Vol. 8, Pages 536: Comparative Analysis of the YABBY Gene Family of Bienertia sinuspersici, a Single-Cell C4 Plant Plants doi: 10.3390/plants8120536 Authors: Soundararajan Won Park Lee Kim The emergence and expression of the YABBY gene family (YGF) coincided with the evolution of leaves in seed plants, and was integral to the early evidence of lamina followed by reproductive...
Molecules, Vol. 24, Pages 4263: Bioactive Plant Compounds in Coffee Charcoal (Coffeae carbo) Extract Inhibit Cytokine Release from Activated Human THP-1 MacrophagesMolecules, Vol. 24, Pages 4263: Bioactive Plant Compounds in Coffee Charcoal (Coffeae carbo) Extract Inhibit Cytokine Release from Activated Human THP-1 Macrophages Molecules doi: 10.3390/molecules24234263 Authors: Weber Hammoud Mahdi Jankuhn Lipowicz Vissiennon The herbal preparation coffee charcoal is produced by over-roasting and milling...
International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 5863: Genome-Wide Analysis of the YABBY Transcription Factor Family in Pineapple and Functional Identification of AcYABBY4 Involvement in Salt StressIJMS, Vol. 20, Pages 5863: Genome-Wide Analysis of the YABBY Transcription Factor Family in Pineapple and Functional Identification of AcYABBY4 Involvement in Salt Stress International Journal of Molecular Sciences doi: 10.3390/ijms20235863 Authors: Zeyun Li Gang Li Mingxing Cai Samaranayaka...
International Journal of Environmental Research and Public Health,IJERPH, Vol. 16, Pages 4669: The Effect of Treatment during A Haze/Post-Haze Year on Subsequent Respiratory Morbidity Status among Successful Treatment Tuberculosis CasesIJERPH, Vol. 16, Pages 4669: The Effect of Treatment during A Haze/Post-Haze Year on Subsequent Respiratory Morbidity Status among Successful Treatment Tuberculosis Cases International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16234669...
Antibiotics, Vol. 8, Pages 233: Novel Tetracyclines Versus Alternative Antibiotics for Treating Acute Bacterial Infection: A Meta-Analysis of Randomized Controlled TrialsAntibiotics, Vol. 8, Pages 233: Novel Tetracyclines Versus Alternative Antibiotics for Treating Acute Bacterial Infection: A Meta-Analysis of Randomized Controlled Trials Antibiotics doi: 10.3390/antibiotics8040233 Authors: Lan Lin Chang Lu Lai Wang Chao This meta-analysis assessed the efficacy and safety of novel tetracyclines for...
Solitary fibrous tumor: a case series identifying pathological adverse factors—implications for risk stratification and classificationAbstractSolitary fibrous tumors (SFTs) are a rare type of mesenchymal lesion in which specific clinicopathologic factors have been related to patient outcome. We collected clinical, pathological, and molecular data of 28 patients with histologically confirmed SFT having at least one pathological factor associated with aggressive behavior. Molecular analysis to detect NAB2/STAT6 gene...
Nutrient Limitation in a Coastal System Influenced by Mussel Farming, River Outflow and On-shore Circulation of WatersAbstractThe aim of this study was to investigate nutrient availability for mussel growth in the coastal waters of NW Thessaloniki Gulf (Greece). Nutrient and chlorophyll-a measurements were taken on a monthly basis during 2014–15, along an experimental line of mussels growing in suspension and in the open sea, outside the area of intensive mussel farming. The results are based on...
Risk of injury to the femoral blood vessels based on the extent of acetabular dysplasia in total hip arthroplastyAbstractWe evaluated the course of the femoral blood vessels of patients with acetabular dysplasia. Patients were divided into five groups: those with Crowe type I, II, III, and IV dysplastic hips and those with normal hips. A computed tomography-based hip navigation software was used to measure the distance between the femoral blood vessels and the anterior pelvic wall in four axial planes...
Affective dysregulation: a transdiagnostic research concept between ADHD, aggressive behavior conditions and borderline personality traitsBaclofen as an adjuvant therapy for autism: a randomized, double-blind, placebo-controlled trialAbstractIncreasing evidence suggests that the function of the GABAergic system is abnormally low in autism spectrum disorder (ASD). Baclofen, which functions as a selective agonist for GABAB receptors, does appear promising for the treatment of ASD. We conducted a 10-week...
Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male miceIt has been brought to our attention that Fig. 5a showing the vasculature in islets of control flox mice is not in fact an endocrine cell but rather exocrine tissue.UpfrontExtracellular vesicles in metabolic diseaseAbstractExtracellular vesicles (EVs) are submicron-sized lipid envelopes that are produced and released from a parent cell and can be taken up by a recipient cell....
Body fatness, diabetes, physical activity and risk of kidney stones: a systematic review and meta-analysis of cohort studiesSoy intake and breast cancer risk: a prospective study of 300,000 Chinese women and a dose–response meta-analysisAbstractEpidemiological evidence on the association of soy intake with breast cancer risk is still inconsistent due to different soy intake levels across previous studies and small number of breast cancer cases. We aimed to investigate this issue by analyzing data...
CPAP Compliance in Obstructive Sleep ApneaThe article "CPAP Compliance in Obstructive Sleep Apnea" written by Manvir Bhatia, was originally published electronically on the publisher's internet portal (currently SpringerLink) on August 10, 2019 with open access. With the author(s) decision to step back from Open Choice, the copyright of the article changed to © Springer Nature Singapore Pte Ltd. 2019 and the article is forthwith distributed under the terms of copyright.A Case of Severe Delayed Sleep–Wake...
TAF and TDF attenuate liver fibrosis through NS5ATP9, TGFβ1/Smad3, and NF-κB/NLRP3 inflammasome signaling pathwaysAbstractBackgroundThis study aimed to investigate the roles and mechanisms of tenofovir alafenamide fumarate (TAF)/tenofovir disoproxil fumarate (TDF) in treating liver fibrosis.MethodsThe effects of TAF/TDF on carbon tetrachloride (CCl4)-induced liver fibrosis in C57BL/6 wild-type or nonstructural protein 5A transactivated protein 9 (NS5ATP9) knockout mice were studied. The differentiation,...
Nuclear atypia in Pindborg tumor: An unexplored phenomenon of a well recognized entityDeepak Pandiar, Rahul Anand, Mala KambojIn Press, Corrected Proof, Available online 23 November 2019Purchase PDFselect article A new wave of oral cancer epidemic among youth in PakistanCorrespondenceNo accessA new wave of oral cancer epidemic among youth in PakistanTayyaba, Nida Akram, Fawad Ur RehmanIn Press, Corrected Proof, Available online 21 November 2019Purchase PDFselect article Teeth extraction revealing...
A longitudinal qualitative evaluation of patient perspectives of adverse events after pelvic reconstruction surgery'A case of mesh erosion in the ureter eight years after a tension-free vaginal mesh surgeryVentral-onlay buccal mucosal graft urethroplasty for the treatment of female urethral stricture: a step-by-step video for Female Pelvic Reconstructive SurgeonsAbstractIntroduction and hypothesisFemale urethral stricture is a relatively uncommon disease. Conservative management with repeated urethral...
The Training Room,The Value of Senior Mentorship Among Orthopaedic SurgeonsSalazar, Dane H.; Schiff, Adam P.; Light, Terry R.Journal of the American Academy of Orthopaedic Surgeons. 27(23):861-867, December 1, 2019.AbstractFavorites PDF Get Content & PermissionsTable of Contents Outline | Back to Top Review ArticleHamstring Injuries in Athletes: Evidence-based TreatmentArner, Justin W.; McClincy, Michael P.; Bradley, James P.Journal of the American Academy of Orthopaedic Surgeons. 27(23):868-877,...
Total parathyroidectomy plus multi-point subcutaneous transplantation in the forearm may be a reliable surgical approach for patients with end-stage renal disease: A case reportRationale: We studied the feasibility of total arathyroidectomy(tPTX)+multi-point transplantation in the forearm for treatment of secondary hyperparathyroidism. Considering the controversial nature of the appropriate timing for and location of this type of surgery, relevant research is relatively rare. Our experience may be...
Trauma-Informed Nursing Improves Equity,Journal of Forensic Nursing 2018 Articles of the YearAdvancing Health Equity and Social Justice in Forensic Nursing Research, Education, Practice, and Policy: Introducing Structural Violence and Trauma- and Violence-Informed CareInitial conceptualizations of violence and trauma in forensic nursing have remained relatively narrowly defined since the specialty's inception. The advent of trauma-informed care has been important but has limitations that obfuscate...
State Health Official Career Advancement and Sustainability Evaluation—Description of the Methods Used in the SHO-CASE StudyState health officials (SHOs) lead state governmental public health agencies, playing an important role in their states. However, little comprehensive research has examined SHOs or characteristics of these leaders, limiting evidence about ways to improve SHO selection and subsequent performance. This brief describes the methods of the SHO-CASE study focused on current and former...
The anesthesia airway evaluation: Correlation with sleep endoscopy findingsMichael Eggerstedt, Matthew J. Urban, Emily Chi, Ethan M. Ritz, Phillip LosavioIn Press, Journal Pre-proof, Available online 23 November 2019Purchase PDFArticle previewAbstractAbstractPurposeDrug-induced sleep endoscopy (DISE) is a cost-effective, safe, and reliable tool to evaluate obstructive sleep apnea (OSA) patients by revealing upper airway sites, patterns, and severity of obstruction. DISE provides valuable data because...
Timing of Complementary Feeding Introduction and Adiposity Throughout Childhood,Véronique Gingras, Izzuddin M. Aris, Sheryl L. Rifas-Shiman, Karen M. Switkowski, Emily Oken and Marie-France HivertPediatrics November 2019, e20191320; DOI: https://doi.org/10.1542/peds.2019-1320 Download PDFAbstractSharePlay VideoVideo AbstractThis study examines associations of timing of CF introduction with adiposity throughout childhood and adolescence in the US Project Viva prospective cohort study.OBJECTIVES: To...
Interventions for Occluded Central Venous Catheters: A Meta-analysis,Ana Cristina Carvalho da Costa, Nayara Narley Pires Vieira, Christiane Inocêncio Vasques, Elaine Barros Ferreira, Eliete Neves Silva Guerra and Paula Elaine Diniz dos ReisPediatrics November 2019, e20183789; DOI: https://doi.org/10.1542/peds.2018-3789ArticleFigures & DataSupplementalInfo & MetricsCommentsThis article requires a subscription to view the full text. If you have a subscription you may use the login form below...
Static and Dynamic Transpulmonary Driving Pressures Affect Lung and Diaphragm Injury during Pressure-controlled versus Pressure-support Ventilation in Experimental Mild Lung Injury in RatsEliete F. Pinto, M.Sc.; Raquel S. Santos, Ph.D.; Mariana A. Antunes, Ph.D.; Ligia A. Maia, Ph.D.; Gisele A. Padilha, Ph.D.; et alJoana de A. Machado, M.S.; Anna C. F. Carvalho, M.S.; Marcos V. S. Fernandes, M.S.; Vera L. Capelozzi, M.D., Ph.D.; Marcelo Gama de Abreu, M.D., Ph.D.; Paolo Pelosi, M.D., F.E.R.S.; Patricia...
Regional atmospheric pollutant transport mechanisms over the North China Plain driven by topography and planetary boundary layer processesPublication date: 15 January 2020Source: Atmospheric Environment, Volume 221Author(s): Jiannong Quan, Youjun Dou, Xiujuan Zhao, Quan Liu, Zhaobin Sun, Yubing Pan, Xingcan Jia, Zhigang Cheng, Pengkun Ma, Jie Su, Jinyuan Xin, Yangang LiuAbstractComprehensive measurements were conducted in winter 2018 and combined with RMPAS-Chem model simulations to analyze the regional...
Glial mitochondrial function and dysfunction in health and neurodegenerationPublication date: December 2019Source: Molecular and Cellular Neuroscience, Volume 101Author(s): Kevin McAvoy, Hibiki KawamataAbstractMitochondria play essential metabolic roles in neural cells. Mitochondrial dysfunction has profound effects on the brain. In primary mitochondrial diseases, mutations that impair specific oxidative phosphorylation (OXPHOS) proteins or OXPHOS assembly factors lead to isolated biochemical defects...
Be Antibiotics Aware is the Centers for Disease Control and Prevention's (CDC) national educational effort to help improve antibiotic prescribing and use and combat antibiotic resistance.Read More >NorovirusYou can help protect yourself and others from norovirus by washing your hands thoroughly with soap and water and following other simple prevention tips.Read More > En EspañolDisease of the WeekLung CancerImage of the WeekEmerson RespiratorEbola Outbreak Responder StoriesCongo-born CDC Photographer...
Medicina Interna | Noviembre 22, Nº 944Producido por la Sociedad Iberoamericana de Información Científica (SIIC)ARTÍCULOS DE FUENTES SELECCIONADASLos artículos de fuentes seleccionadas son resumidos en castellano por el Comité de Redacción Científica de SIIC.Javier Gallego PlazasDETECCIÓN PROBABILÍSTICA DE CÁNCER COLORRECTAL MEDIANTE EL ANÁLISIS DE SANGRE RUTINARIOMediante el análisis de sangre es posible evaluar la inmunovigilancia frente a la aparición de neoplasias. El análisis de megadatos permitió...
Lifecycle Regulation of Artificial Intelligence– and Machine Learning–Based Software Devices in MedicineThomas J. Hwang, AB; Aaron S. Kesselheim, MD, JD, MPH; Kerstin N. Vokinger, MD, JD, PhDEditorial: Evaluating Machine Learning Articles; Finale Doshi-Velez, PhD; Roy H. Perlis, MD, MScMachine Learning, Predictive Analytics, and Clinical Practice: Can the Past Inform the Present?Eric D. Peterson, MD, MPHEditorial: Evaluating Machine Learning Articles; Finale Doshi-Velez, PhD; Roy H. Perlis, MD, MScAddressing...
The diagnostic and prognostic roles of serum irisin in bladder cancerPublication date: Available online 20 November 2019Source: Current Problems in CancerAuthor(s): Marwa M. Esawy, Khalid M. Abdel-SamdAbstractBackground: Egypt is among the countries with the highest incidence of bladder cancer (BC). Adipokines involved in BC development. This study aimed to examine the diagnostic and prognostic roles of irisin in BC through its function as an adipokine. Patients and methods: This study included 150...
Sacrococcygeal teratoma with intraspinal extensionPublication date: January 2020Source: Journal of Pediatric Surgery Case Reports, Volume 52Author(s): G. Frongia, M. Kessler, H. Bächli, J. Kunz, J.P. Schenk, M. Elsässer, B. Beedgen, A. Mehrabi, P. GüntherAbstractWe report a case series of two newborns with a sacrococcygeal teratoma (SCT) with intraspinal involvement. In one case, the SCT was detected prenatally and presented postnatally as a large mass of 8 × 10 × 10 cm. In the second case the prenatal...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,Surgical and Nonsurgical Lines of Treatment of Reinke's Edema: A Systematic Literature ReviewThe aim of this study was to carry out a systematic review of different surgical and nonsurgical lines of treatment of Reinke's edema to identify the effectiveness and the guidelines described to use each of them.Olfactory Ecto-Mesenchymal Stem Cells in Laryngeal Nerve Regeneration...
Surgical and Nonsurgical Lines of Treatment of Reinke's Edema: A Systematic Literature ReviewThe aim of this study was to carry out a systematic review of different surgical and nonsurgical lines of treatment of Reinke's edema to identify the effectiveness and the guidelines described to use each of them.Olfactory Ecto-Mesenchymal Stem Cells in Laryngeal Nerve Regeneration in RatsSelective intralaryngeal reinnervation has been shown to be effective in experimental models. This consists of independently...
Why State Medicaid Programs Should Cover Hearing Aids for Adults,Amber Willink, PhD; Mary Ann Hernando, MPH; Sarah Steege, JD, MPPORIGINAL INVESTIGATIONAssociation of Delayed Time to Treatment Initiation With Overall Survival and Recurrence Among Patients With Head and Neck Squamous Cell Carcinoma in an Underserved Urban PopulationDavid Z. Liao, BE; Nicolas F. Schlecht, PhD; Gregory Rosenblatt, PhD; et al.Earn CME creditInvited Commentary: Delivering Timely Head and Neck Cancer Care to an Underserved...
Social Sciences, Vol. 8, Pages 321: Big Data and Employee Wellbeing: Walking the Tightrope between Utopia and DystopiaSocial Sciences, Vol. 8, Pages 321: Big Data and Employee Wellbeing: Walking the Tightrope between Utopia and Dystopia Social Sciences doi: 10.3390/socsci8120321 Authors: Carolyn Axtell Mark Taylor Bridgette Wessels This special issue was inspired by an Economic & Social Research Council funded seminar series that explored the possibilities for using Big Data and data analytics...
Molecules, Vol. 24, Pages 4234: Immobilization of Naringinase from Penicillium decumbens on Chitosan Microspheres for Debittering Grapefruit JuiceMolecules, Vol. 24, Pages 4234: Immobilization of Naringinase from Penicillium decumbens on Chitosan Microspheres for Debittering Grapefruit Juice Molecules doi: 10.3390/molecules24234234 Authors: Joanna Bodakowska-Boczniewicz Zbigniew Garncarek Naringinase is an enzyme complex which exhibits α-l-rhamnosidase and β-d-glucosidase activity. This enzymatic...
Journal of Clinical Medicine,JCM, Vol. 8, Pages 2041: Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC)JCM, Vol. 8, Pages 2041: Prognostic Value of MiR-21: An Updated Meta-Analysis in Head and Neck Squamous Cell Carcinoma (HNSCC) Journal of Clinical Medicine doi: 10.3390/jcm8122041 Authors: Irimie-Aghiorghiesei Pop-Bica Pintea Braicu Cojocneanu Zimța Gulei Slabý Berindan-Neagoe Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies...
International Journal of Environmental Research and Public Health, IJERPH, Vol. 16, Pages 4632: Association of Serum Uric Acid with Cardiovascular Disease Risk Scores in KoreansIJERPH, Vol. 16, Pages 4632: Association of Serum Uric Acid with Cardiovascular Disease Risk Scores in Koreans International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16234632 Authors: Seung Yun Lee Won Park Young Ju Suh Mie Jin Lim Seong-Ryul Kwon Joo-Hyun Lee Young Bin Joo Youn-Kyung Oh Kyong-Hee...
Cancers, Vol. 11, Pages 1834: Overcoming Ibrutinib Resistance in Chronic Lymphocytic LeukemiaCancers, Vol. 11, Pages 1834: Overcoming Ibrutinib Resistance in Chronic Lymphocytic Leukemia Cancers doi: 10.3390/cancers11121834 Authors: Puła Gołos Górniak Jamroziak Ibrutinib is the first Bruton's tyrosine kinase (BTK) inhibitor, which showed significant clinical activity in chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) patients regardless of cytogenetic risk factors. Recent...
Antibiotics, Vol. 8, Pages 230: Harnessing the Potential of Killers and Altruists within the Microbial Community: A Possible Alternative to Antibiotic Therapy?Antibiotics, Vol. 8, Pages 230: Harnessing the Potential of Killers and Altruists within the Microbial Community: A Possible Alternative to Antibiotic Therapy? Antibiotics doi: 10.3390/antibiotics8040230 Authors: Ikryannikova Kurbatov Soond Zamyatnin In the context of a post-antibiotic era, the phenomenon of microbial allolysis, which is defined...
Oncology,Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.Related ArticlesTargeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas. Cell Rep. 2019 Nov 19;29(8):2321-2337.e7 Authors: Yamagishi M, Hori M, Fujikawa D, Ohsugi T, Honma D, Adachi N, Katano H, Hishima T, Kobayashi S, Nakano K, Nakashima M, Iwanaga M, Utsunomiya A, Tanaka Y, Okada S, Tsukasaki...
Effects of chemical and mechanical stimulation on laryngeal motion during alfaxalone, thiopentone or propofol anaesthesia in healthy dogs.Related ArticlesEffects of chemical and mechanical stimulation on laryngeal motion during alfaxalone, thiopentone or propofol anaesthesia in healthy dogs. Vet Anaesth Analg. 2019 Jul;46(4):435-442 Authors: Labuscagne S, Zeiler GE, Dzikiti BT Abstract OBJECTIVE: To compare the effect of chemical and mechanical stimulation on arytenoid cartilage motion during anaesthetic...
pubmed: snoring,Tracheostomy and mandibular distraction in acute sleep apnea.Related ArticlesTracheostomy and mandibular distraction in acute sleep apnea. Indian J Dent Res. 2019 Jul-Aug;30(4):625-629 Authors: Balaji SM, Balaji P Abstract Severe restriction of airway volume in the orofacial region, caused by temporomandibular joint (TMJ) ankylosis, may lead to obstructive sleep apnea (OSA). If the TMJ ankylosis is progressive, rarely, the caregivers may fail to notice the problem. Such patients...
pubmed: "drug chem toxicol"[...Correction.Related ArticlesCorrection. Drug Chem Toxicol. 2019 Nov 20;:1 Authors: PMID: 31746247 [PubMed - as supplied by publisher]pubmed: "drug chem toxicol"[...Thu Nov 21, 2019 14:49Long-term consumption of alcohol exacerbates neural lesions by destroying the functional integrity of the blood-brain barrier.Related ArticlesLong-term consumption of alcohol exacerbates neural lesions by destroying the functional integrity of the blood-brain barrier. Drug Chem Toxicol....
Latest Results for Radiation and Environmental Biophysics,Modeling of chromosome aberration response functions induced by particle beams with different LETAbstract This study is based on our already published experimental data (Kowalska et al. in Radiat Environ Biophys 58:99–108, 2019) and is devoted to modeling of chromosome aberrations in human lymphocytes induced by 22.1 MeV/u 11B ions, 199 MeV/u 12C ions, 150 MeV and spread-out Bragg peak (SOBP) proton beams as well as by 60Co γ rays. The curvature...
Journal of Biophotonics,Comparative analysis of intrinsic skin aging between Caucasian and Asian subjects by slide‐free in vivo harmonic generation microscopyPhenotypical and functional differences in the intrinsic skin aging process of individuals between Caucasians and Asians have generated considerable interest in dermatology and cosmetic industry. Most of the studies focused on the stratum corneum, and in some other studies inter‐individual differences overwhelms the racial difference. None...
Latest Results for Psychopharmacology,Effects of a methamphetamine vaccine, IXT-v100, on methamphetamine-related behaviorsAbstract Rationale: Vaccines have been developed as a potential treatment for methamphetamine (meth) use disorder (MUD). Immunization with the meth vaccine IXT-v100 has previously been shown to elicit antibodies with high affinity for meth and thus may be an effective treatment for MUD. Objectives: These studies were designed to determine the efficacy of...Latest Results for...
Effects of virtual reality technology locomotive multi-sensory motion stimuli on a user simulator sickness and controller intuitiveness during a navigation taskAbstract Simulator sickness of users and intuitiveness of controllers contribute to a user's acceptance or rejection of a virtual reality (VR) experiment. However, few studies investigated the effects of different VR locomotive controllers and potential gender effects. Hence, we investigated the effects of different motion stimuli combinations...
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLCIn patients with advanced or metastatic non–small-cell lung cancer (NSCLC) with mutations in the gene encoding epidermal growth factor receptor (EGFR) that are sensitive to tyrosine kinase inhibitors (TKIs) (exon 19 deletions or L858R point mutations), guidelines recommend treatment with an…NEJM : ResearchThu Nov 21, 2019 02:00An Anti-Opioid System, Courtesy of a Worm ModelThe worm Caenorhabditis elegans is a simple yet powerful...
Nutrition knowledge and attitude in medical students of Tabriz University of Medical Sciences in 2017–2018In this cross-sectional study among 220 medical students we aimed to determine the nutritional knowledge and attitude of medical students through clinical training courses (externship and internship) of Tabriz...BMC Research NotesThu Nov 21, 2019 02:00The spectrum of heart disease among adults at the Bamenda Regional Hospital, North west Cameroon: a semi urban settingWe sought to determine the...
Mimicking exercise: What matters most and where to next?Abstract The past decade has witnessed growing scientific and commercial interest in the identification of bioactive oral compounds that mimic or potentiate the effects of exercise, so‐called "exercise pills" or "exercise mimetics." These compounds have, to date, typically targeted skeletal muscle in an attempt to stimulate some of the adapations to exercise induced by endurance training. Accordingly, they fail to impart many of the broad health...
The Evolution of Neuroscience as a Research Field Relevant to Dentistry.Related ArticlesThe Evolution of Neuroscience as a Research Field Relevant to Dentistry. J Dent Res. 2019 Dec;98(13):1407-1417 Authors: Iwata K, Sessle BJ Abstract The field of neuroscience did not exist as such when the Journal of Dental Research was founded 100 y ago. It has emerged as an important scientific field relevant to dentistry in view of the many neurally based functions manifested in the orofacial area (e.g., pain,...
Surgical and Nonsurgical Lines of Treatment of Reinke's Edema: A Systematic Literature ReviewThe aim of this study was to carry out a systematic review of different surgical and nonsurgical lines of treatment of Reinke's edema to identify the effectiveness and the guidelines described to use each of them.Journal of VoiceThu Nov 21, 2019 02:00Olfactory Ecto-Mesenchymal Stem Cells in Laryngeal Nerve Regeneration in RatsSelective intralaryngeal reinnervation has been shown to be effective in experimental...
Anatomy of the Great Posterior Radiculomedullary Artery [SPINE]BACKGROUND AND PURPOSE:Although considerable variability exists as to the overall caliber of radiculomedullary arteries, dominant radiculomedullary arteries such as the artery of Adamkiewicz exist. The existence of a great posterior radiculomedullary artery has attracted little attention and has been a matter of debate. The aim of this anatomic study was to determine the presence or absence of the great posterior radiculomedullary artery.MATERIALS...
Resonant and non-resonant femtosecond ionization mass spectrometry of organochlorine pesticidesAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01861A, PaperSiddihalu Lakshitha Madunil, Totaro Imasaka, Tomoko ImasakaThirteen organochlorine pesticides in a standard sample mixture were measured by gas chromatography combined with mass spectrometry using an ultraviolet femtosecond laser (267 nm) as the ionization source, and the...The content of this RSS Feed (c) The Royal Society of ChemistryRoyal...
Modified Craniocervical Approach for Resection of the Styloid Process in Patients with Eagle's SyndromeJ Neurol Surg BDOI: 10.1055/s-0039-3400297 Objectives Surgical treatment of Eagle's syndrome remains the mainstay of treatment. Palsy of the marginal mandibular branch of the facial nerve is the most significant complication encountered in transcervical resections, due to direct compression during the approach. We proposed a modification of the craniocervical approach to the jugular foramen to resect...
Tumors of the conjunctiva and cornea,Carol L Shields, Jerry A ShieldsIndian Journal of Ophthalmology 2019 67(12):1930-1948Tumors of the conjunctiva and cornea comprise a large and varied spectrum of conditions. These tumors are grouped into two major categories of congenital and acquired lesions. The acquired lesions are further subdivided based on origin of the mass into surface epithelial, melanocytic, vascular, fibrous, neural, histiocytic, myxoid, myogenic, lipomatous, lymphoid, leukemic, metastatic...
Future of 5-fluorouracil in cancer therapeutics, current pharmacokinetics issues and a way forwardSania Zafar Iqbal, Farhat Jubeen, Farooq SherJournal of Cancer Research and Practice 2019 6(4):155-161Background: In addition to exhibiting antitumor potential, antitumor drugs exhibit toxicity due to a poor pharmacokinetic profile. An enormous amount of research has been carried out and is still ongoing to obtain more targeted, potent, and safe drugs to treat cancer, and pharmacokinetic evaluations...
Size, site, and signaling: Three attributes of estrogen receptorsJunita Desouza, Sushama Gadkar, Dhanashree Jagtap, Geetanjali SachdevaBiomedical Research Journal 2019 6(2):37-48Estrogens are implicated in a diverse range of functions varying from reproduction, circulation, skeletal health to neuroprotection. Estrogens are also being increasingly recognized for their pathological contribution to cancers of various organs. This has spurred several investigations on estrogen-initiated signaling mechanisms...
Role of nanotechnology in dentistry: Systematic reviewMuhamood Moothedath, Muhaseena Moothedath, Abhishek Jairaj, B Harshitha, Suheel Manzoor Baba, Shafait Ullah KhateebJournal of International Society of Preventive and Community Dentistry 2019 9(6):535-541Aim: This systematic review aimed to provide an overview of role of nanotechnology in dentistry and to evaluate its applicability in prevention and treatment of oral diseases. Materials and Methods: A systematic literature search was conducted...
Analog Retinal Redshifts Visible Absorption of QuasAr Transmembrane Voltage Sensors into Near‐infraredGaoxiang Mei, Natalia Mamaeva, Srividya Ganapathy, Peng Wang, Willem J. DeGrip, Kenneth J. RothschildVersion of Record online: 10 November 2019 QuasAr1 and QuasAr2, mutants of archaerhodopsin‐3, are used in optogenetic applications as fluorescent transmembrane voltage sensors. The native A1 retinal chromophore was substituted with a synthetic retinal analog MMAR containing a methylamino modified...
La prima colazione: il ruolo centrale in una dieta equilibrata,Aspetti nutrizionali e demenza,Il piatto mediterraneo: come si compone?VIDEO IN EVIDENZAAppropriatezza in antibioticoterapiaProf. Giovanni Di PerriDirettore Dipartimento Clinico di Malattie Infettive dell'Università di Torino NOVITÀThe psychic structure of the Substance Use DisorderIcro MaremmaniIn collaboration withAngelo G.I. MaremmaniMatteo PaciniForeword by Pedro Ruizvai alla scheda libro
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,Surgical and Nonsurgical Lines of Treatment of Reinke's Edema: A Systematic Literature ReviewThe aim of this study was to carry out a systematic review of different surgical and nonsurgical lines of treatment of Reinke's edema to identify the effectiveness and the guidelines described to use each of them.Olfactory Ecto-Mesenchymal Stem Cells in Laryngeal Nerve Regeneration...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,