Point of view: Electrophysiological endpoints differ when comparing the mode of action of highly successful anti-arrhythmic drugs in the CAVB dog model with TdP.In the anaesthetized, chronic atrioventricular block (CAVB) dog, ventricular ectopic beats and Torsade de pointes arrhythmias (TdP) are believed to ensue from an abrupt prolongation of ventricular repolarization and increased temporal dispersion of repolarization, quantified as short-term variability (STV). These TdP stop spontaneously or,...
Nutrients, Vol. 11, Pages 2797: Daily Ingestion of Eggplant Powder Improves Blood Pressure and Psychological State in Stressed Individuals: A Randomized Placebo-Controlled StudyNutrients, Vol. 11, Pages 2797: Daily Ingestion of Eggplant Powder Improves Blood Pressure and Psychological State in Stressed Individuals: A Randomized Placebo-Controlled Study Nutrients doi: 10.3390/nu11112797 Authors: Mie Nishimura Miho Suzuki Ryuto Takahashi Shohei Yamaguchi Kazufumi Tsubaki Tomoyuki Fujita Jun Nishihira...
Nanomaterials, Vol. 9, Pages 1630: Fractal Silver Dendrites as 3D SERS Platform for Highly Sensitive Detection of Biomolecules in Hydration ConditionsNanomaterials, Vol. 9, Pages 1630: Fractal Silver Dendrites as 3D SERS Platform for Highly Sensitive Detection of Biomolecules in Hydration Conditions Nanomaterials doi: 10.3390/nano9111630 Authors: Maria José Lo Faro Cristiano D'Andrea Antonio Alessio Leonardi Dario Morganti Alessia Irrera Barbara Fazio In this paper, we report on the realization of...
International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 5760: Stem Cells: The Game Changers of Human Cardiac Disease Modelling and Regenerative MedicineIJMS, Vol. 20, Pages 5760: Stem Cells: The Game Changers of Human Cardiac Disease Modelling and Regenerative Medicine International Journal of Molecular Sciences doi: 10.3390/ijms20225760 Authors: Elvira Immacolata Parrotta Stefania Scalise Luana Scaramuzzino Giovanni Cuda A comprehensive understanding of the molecular basis and mechanisms...
Antibiotics, Vol. 8, Pages 227: Microbial Growth and Biogenic Amine Production in a Balkan-Style Fresh Sausage during Refrigerated Storage under a CO2-Containing Anaerobic Atmosphere: Effect of the Addition of Zataria multiflora Essential Oil and Hops ExtractAntibiotics, Vol. 8, Pages 227: Microbial Growth and Biogenic Amine Production in a Balkan-Style Fresh Sausage during Refrigerated Storage under a CO2-Containing Anaerobic Atmosphere: Effect of the Addition of Zataria multiflora Essential Oil...
Association of participation in the American Board of Physical Medicine and Rehabilitation Maintenance of Certification program and physician disciplinary actionsObjective The study analyzed the relationship between participation in the American Board of Physical Medicine and Rehabilitation (ABPMR) maintenance of certification (MOC) program and the incidence of disciplinary actions (DAs) by state medical boards over a physician's career. The hypothesis is that physicians who do not maintain their...
Anterior cruciate ligament reconstruction in association with medial unicompartmental knee replacement: a retrospective study comparing clinical and radiological outcomes of two different implant designAbstractPurposeUnicompartmental knee arthroplasty (UKA) combined with anterior cruciate ligament (ACL) reconstruction has recently been suggested as a feasible treatment option for young and active patients with medial compartment osteoarthritis (OA) and ACL deficiency. The aim of this study is to...
Light-Based Neuronal Activation: The Future of Cranial Nerve StimulationPublication date: February 2020Source: Otolaryngologic Clinics of North America, Volume 53, Issue 1Author(s): Elliott D. Kozin, M. Christian Brown, Daniel J. Lee, Konstantina M. StankovicHypoglossal Nerve (Cranial Nerve XII) StimulationPublication date: February 2020Source: Otolaryngologic Clinics of North America, Volume 53, Issue 1Author(s): Jason L. Yu, Erica R. ThalerRecurrent Laryngeal Nerve StimulatorPublication date: February...
Oxygen Demand, Uptake, and Deficits in Elite Cross-country Skiers during a 15-km RacePurpose To quantify the repeated oxygen deficits attained during intermittent endurance exercise by measuring oxygen consumption (V[Combining Dot Above]O2) and oxygen demand (V[Combining Dot Above]O2dem) throughout a simulated roller ski race. Methods Eight male elite cross-country skiers (V[Combining Dot Above]O2,peak 77.4 ± 4.4 mL·min-1·kg-1) raced a 13.5 km roller ski time-trial on a World Cup course. On two additional...
Diagenetic changes on bone histology of Quaternary mammals from a tropical cave deposit in southeastern BrazilPublication date: 1 January 2020Source: Palaeogeography, Palaeoclimatology, Palaeoecology, Volume 537Author(s): Elver Luiz Mayer, Alex Hubbe, Jennifer Botha-Brink, Ana Maria Ribeiro, Paulo Miguel Haddad-Martim, Walter NevesAbstractKarst caves are suitable environments for the accumulation and preservation of fossils. Cave deposits are often complex and the environmental conditions within...
Prevention and Management of Serious Complications After Facial Fat GraftingPublication date: January 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 1Author(s): Ping Song, Xiao Xu, Minliang Chen, Lee L.Q. PuFat Grafting for Treatment of Facial SclerodermaPublication date: January 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 1Author(s): Aurélie Daumas, Jeremy Magalon, Flore Delaunay, Maxime Abellan, Cécile Philandrianos, Florence Sabatier, Brigitte Granel, Guy MagalonFat Grafting...
Fragmented realities: the 'sectarianisation' of space among Iraqi Shias in LondonAbstractHow do the spaces we inhabit shape our lived experiences? And how do those lived experiences in turn come to shape and influence our political subjectivity? Such questions are rendered all the more important in studies of migrant or diaspora populations who, by definition, conduct their daily lives in spaces and places that were initially alien to them. The way in which migrants interact with the spaces around...
Intraoperative Placement of Paravertebral Catheters to Manage Postoperative Pain in Opioid-Dependent Patients After Thoracolumbar Spine Fusion Surgery: A Case ReportWe introduce a regional technique that involves the intraoperative placement of bilateral paravertebral catheters under direct visualization. The patient had stage IV lung cancer and was on chronic oxycodone therapy. He presented with a T10 metastatic lesion, and underwent spinal decompression with T7–L1 fusion and T10 corpectomy. Before...
Evaluation of 99mTC-ECD SPECT/CT brain Imaging with NeuroGam analysis in Moyamoya disease after surgical revascularizationTo evaluate the clinical value of NeuroGam software in assessing the brain foci perfusion changes by 99mTC-ECD single photon emission computed tomography/computed tomography (SPECT/CT) brain imaging in patients with Moyamoya Disease (MMD). Seventy-two patients with MMD who underwent superficial temporal artery-middle cerebral artery (STA-MCA) bypass combined with encephalo-duro-myo-synangiosis...
Prioritizing Physical Activity in Schools: Educational Leaders' PerspectivesPurpose The purpose of this study was to assess the perspectives of diverse school leaders relative to feasible physical activity (PA) policies and practices. Objectives Our main objective was to identify barriers to school PA and find creative solutions for overcoming them. A secondary objective was to assess school leaders' perspectives on the integration of health and education as a function of ASCD's (the largest professional...
Thyroid Disease in Pregnancy,Bhatt, Shweta J. MD; Pinho, Gabriella MD; Morelli, Sara S. MD, PhDTopics in Obstetrics & Gynecology: December 31, 2019 - Volume 39 - Issue 18 - p 1–7doi: 10.1097/01.PGO.0000615660.61696.20
Two-Stage Combined Ortho-Plastic Management of Type IIIB Open Diaphyseal Tibial Fractures Requiring Flap Coverage: Is the Timing of Debridement and Coverage Associated With Outcomes?Objective: To delineate whether timing to initial debridement and definitive treatment had an effect on patient outcomes in those undergoing 2-stage ortho-plastic management of Gustilo–Anderson type IIIB open tibial diaphyseal fractures. Design: Retrospective comparative cohort study over a 2-year period. Setting: Level...
Supporting the supporter: a focus on families of patients with chronic obstructive pulmonary diseaseNo abstract availableFamily members' experiences and expectations of self-management counseling while caring for a person with chronic obstructive pulmonary disease: a systematic review of qualitative evidenceObjective: The objective of this review was to identify and synthesize existing evidence on the experiences and expectations of self-management counseling of adult family members who are informal...
Evaluation of an After-Hours Child Passenger Safety Resource GuideMotor vehicle crashes are a leading cause of unintentional injury deaths for children in the United States. Child safety seats are effective in reducing the rate and severity of injury for children. Families seen in an emergency department (ED) outside of injury prevention (IP) operational hours may not have the same opportunity to obtain a child safety seat due to the unavailability of IP resources. This study evaluated the effectiveness...
Forensic Spermatozoa DetectionSemen is crucial evidence for some sex crimes, with its sole confirmation being sperm detection. The success of sperm detection is dependent on all levels of preanalytic and analytic procedures. Specimen collection must be performed by well-trained and competent forensic physicians as well as forensic nurses, with preservation done properly before laboratory transfer. Laboratory procedures should consider archival sperm identification, by visualization, with adequate...
Fit-For-Purpose PD-L1 Biomarker Testing For Patient Selection in Immuno-Oncology: Guidelines For Clinical Laboratories From the Canadian Association of Pathologists-Association Canadienne Des Pathologistes (CAP-ACP)Since 2014, programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) checkpoint inhibitors have been approved by various regulatory agencies for the treatment of multiple cancers including melanoma, lung cancer, urothelial carcinoma, renal cell carcinoma, head and...
Risperidone Combination Therapy With Propentofylline for Treatment of Irritability in Autism Spectrum Disorders: A Randomized, Double-Blind, Placebo-Controlled Clinical TrialObjectives Propentofylline is a xanthine phosphodiesterase inhibitor and adenosine reuptake blocker with neuroprotective effects linked to anti-inflammatory and antiexcitatory properties. This is a double-blind, placebo-controlled trial investigating the potential beneficial effects of propentofylline, as an adjunctive treatment...
Toward Increased Understanding of the Steroid Controversy in Septic ShockNo abstract availableWhich Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic ReviewObjectives: To determine which multicenter randomized controlled trials in critically ill patients have shown that the study intervention was associated with a statistically significant reduction in mortality. Our analysis provides an update to a report published 10 years ago. Data Sources:...
Yet another perineural layer: so what?Miguel A Reina, Andre Boezaart, Olga C Nin et al. (2019-11-04)10.1136/rapm-2019-100765Pain medicine: if we want to be surgeons, we must have surgical trainingJonathan M Hagedorn, Tim Deer, Dawood Sayed et al. (2019-11-08)10.1136/rapm-2019-101105Refining a great idea: the consolidation of PECS I, PECS II and serratus blocks into a single thoracic fascial plane block, the SAP block—a concern on the muscle painHongye Zhang, Yongsheng Miao, Zongyang Qu (2019-10-25)10.1136/rapm-2019-101042Erector...
Medicina Interna | Noviembre 15, Nº 943Producido por la Sociedad Iberoamericana de Información Científica (SIIC)ARTÍCULOS DE FUENTES SELECCIONADASLos artículos de fuentes seleccionadas son resumidos en castellano por el Comité de Redacción Científica de SIIC.Renato CozziTRATAMIENTO COMBINADO CON DROGAS DOPAMINERGICAS Y SOMATOSTATINERGICAS EN PACIENTES CON ACROMEGALIAEn los pacientes con acromegalia, la normalización de los niveles de hormona de crecimiento y de factor de crecimiento tipo I similar...
Isolation, technological characterization and in vitro probiotic evaluation of Lactococcus strains from traditional Turkish skin bag Tulum cheesesAbstractPurposeThe present study was undertaken to evaluate in vitro prerequisite probiotic and technological characteristics of ten Lactococcus strains isolated from traditional goat skin bags of Tulum cheeses from the Central Taurus mountain range in Turkey.MethodsAll isolates were identified based on the nucleotide sequences of the 16S rRNA gene. Eight...
Treatment of Functional Mitral Regurgitation in Heart FailureAbstractPurpose of ReviewTo analyze the current state of the art of functional mitral regurgitation (FMR) treatment.Recent FindingsThe first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan needs further assessment. Valvular intervention may be considered in FMR symptomatic patients despite GMT, and can be...
An artificial miRNA as a new tool to silence and explore gene functions in appleAbstractArtificial miRNA (amiRNA) is a powerful technology to silence genes of interest. It has a high efficiency and specificity that can be used to explore gene function through targeted gene regulation or to create new traits. To develop this gene regulation tool in apple, we designed two amiRNA constructs based on an apple endogenous miRNA backbone previously characterized (Md-miR156h), and we checked their efficiency...
Cardiac Autonomic Neuropathy in Obesity, Metabolic Syndrome and Prediabetes: A Narrative ReviewThe authors of the article would like to amend the article title to 'Cardiac Autonomic Neuropathy in Obesity, Metabolic Syndrome and Prediabetes: A Narrative Review'.Is There a Role for Informal Caregivers in the Management of Diabetic Foot Ulcers? A Narrative ReviewAbstractSuccessful management of diabetic foot ulceration (DFU) is crucial for preventing long-term morbidity and lowering risk of amputations....
European Society of Neuroradiology (ESNR)Prediction of high proliferative index in pituitary macroadenomas using MRI-based radiomics and machine learningAbstractPurposePituitary adenomas are among the most frequent intracranial tumors. They may exhibit clinically aggressive behavior, with recurrent disease and resistance to multimodal therapy. The ki-67 labeling index represents a proliferative marker which correlates with pituitary adenoma aggressiveness. Aim of our study was to assess the accuracy...
The variability of pollen concentrations at two stations in the city of Wrocław in PolandIn the original publication of the article, the SPIn values in Tables 1 and 4 were incorrectly published. The correct Tables 1 and 4 are given below.Rapid pollen rupture and release of pollen cytoplasmic granules upon hydration of allergenic grass and weed species commonly found in subtropical regionsAbstractAirborne pollen is an important and potent source of allergens. Allergenic protein components located...
Ethics education should make room for emotions: a qualitative study of medical ethics teaching in Indonesia and the NetherlandsAbstractStudies have shown that students may feel emotional discomfort when they are asked to identify ethical problems which they have encountered during their training. Teachers in medical ethics, however, more often focus on the cognitive and rational ethical aspects and not much on students' emotions. The purpose of this qualitative study was to explore students' feelings...
Adhesion Evaluation of AG200-15: An Investigational Transdermal Contraceptive Delivery SystemAbstractIntroductionAG200-15, an investigational transdermal contraceptive delivery system or patch, is designed to be a low-dose, non-daily, combined hormonal contraceptive option for women. In this phase 1 study, the in vivo adhesion of the AG200-15 patch was compared to Xulane®, the only contraceptive patch available in the USA.MethodsThis phase 1, randomized, open-label, single-dose, two-treatment, two-period...
Moral reasoning of Chinese accounting students and practitionersAbstractThis exploratory study employs the Defining Issues Test (DIT2) to investigate the moral reasoning levels of a sample of 228 accounting students at Xi'an Jiaotong University, Xi'an, and 192 accounting practitioners from different regions of China. The results show that on average, the P scores (a measure of the post-conventional level of moral development) of Chinese accounting students and practitioners are 45.02 and 33.57, respectively....
Mitogenome analysis of dwarf pufferfish ( Carinotetraodon travancoricus ) endemic to southwest India and its implications in the phylogeny of TetraodontidaeAbstractThe Tetraodontidae (pufferfishes), is primarily a family of marine and estuarine fishes with a limited number of freshwater species. Freshwater invasions can be observed in South America, Southeast Asia and central Africa. In the present study, we have analysed the complete mitogenome of freshwater pufferfish, Carinotetraodon travancoricus (dwarf...
Klinische Untersuchung des KniesZusammenfassungDie klinische Untersuchung des Kniegelenks stellt zum einen eine große Herausforderung, zum anderen aber auch eine große Chance dar. Insbesondere ligamentäre Verletzungen werden trotz ihrer Komplexität immer besser verstanden und somit auch differenzierter therapiert. Eine rein radiologische Diagnosestellung ist v. a. bei chronischen Verletzungen nur begrenzt möglich. Daher ist die differenzierte klinische Untersuchung zur Diagnostizierung komplexer...
Investigating the foreign language effect as a mitigating influence on the 'optimality bias' in moral judgementsAbstractBilinguals often display reduced emotional resonance their second language (L2) and therefore tend to be less prone to decision-making biases in their L2 (e.g., Costa et al. in Cognition 130(2):236–254, 2014a, PLoS One 9(4):1–7, 2014b)—a phenomenon coined Foreign Language Effect (FLE). The present pre-registered experiments investigated whether FLE can mitigate a special case of...
Visual noise consisting of X-junctions has only a minimal adverse effect on object recognitionAbstractIn 1968, Guzman showed that the myriad of surfaces composing a highly complex and novel assemblage of volumes can readily be assigned to their appropriate volumes in terms of the constraints offered by the vertices of coterminating edges. Of particular importance was the L-vertex, produced by the cotermination of two contours, which provides strong evidence for the termination of a 2-D surface. An...
Upcoming Events in Pediatric CardiologyChemotherapy-Induced Cardiotoxicity in Adolescent After Heart Transplant: Do Not Forget the Right VentricleAbstractThe evaluation of oncologic patients at risk of chemotherapy-induced cardiotoxicity usually focuses on left ventricular function. However, recent studies have demonstrated that right ventricle impairment often coexists (and in some cases precedes) left-side affectation. We present the case of a 19-year-old heart transplant recipient who developed...
The diagnostic value of SNpc using NM-MRI in Parkinson's disease: meta-analysisThe above article was published online with incorrect author name. The right spelling should be Xiangming Wang instead of Xiangmin Wang. The correct name is presented here. The original article has been corrected.Agenesis of internal carotid artery and deformation of caudate and nucleus accumbensA case of recurrent vomiting: extending the spectrum of neuronal intranuclear inclusion diseaseHeadache and vision loss in a...
Coase and transaction costs reconsidered: the case of the English lighthouse systemAbstractWhat is Coase's understanding of transaction costs in economic theory and history? Our argument in this paper is twofold, one theoretical and the other empirical. First, Coase regarded positive transaction costs as the beginning, not the end, of any analysis of market processes. From a Coasean perspective, positive transaction costs represent a profit opportunity for entrepreneurs to erode such transaction...
Xenarthran Synsacrum Morphology and EvolutionAbstractXenarthra is unique in having striking features in the axial skeleton, usually very different from the rest of the eutherian clades. Some of these features are widely spread among the members of the group (e.g., the presence of xenarthrales in most cingulates and all pilosans, and the synsacrum with sacroischial union to the pelvis in almost all xenarthrans) and others are restricted to some taxa (e.g., deviated number of cervical vertebrae in Bradypus and Choloepus)....
rAAV6-mediated miR-29b delivery suppresses renal fibrosisAbstractBackgroundPrevious studies showed that microRNA-29b (miR-29b) inhibits renal fibrosis. Therefore, miR-29b replacement therapy represents a promising approach for treating renal fibrosis. However, an efficient method of kidney-targeted miRNA delivery has yet to be established. Recombinant adeno-associated virus (rAAV) vectors have great potential for clinical application. For kidney-targeted gene delivery, the most suitable AAV serotype...
Qualität und Effektivität der interdisziplinären multimodalen SchmerztherapieKeine Evidenz für die Abschwächung der analgetischen Opioidwirkung durch peripher wirksame µ‑OpioidrezeptorantagonistenErratum zu: Dronabinol bei geriatrischen Schmerz- und PalliativpatientenErratum zu:Schmerz 2019https://doi.org/10.1007/s00482-019-00408-1Im ursprünglich veröffentlichten Beitrag wurde in Abb. 3 eine fehlerhafte Legende dargestellt. Sowohl in der Online- als auch der Printversion des Beitrags wurde der Fehler...
Not All Pericardiac Fluid Is Pericardial: Ultrasound of Pericardial Effusion and Two of Its MimicsYuriy S. Bronshteyn, M.D., F.A.S.E.; Jennifer N. Hauck, M.D.; Rebecca A. Schroeder, M.D.; Atilio Barbeito, M.D., M.P.H. Author NotesFrom the Department of Anesthesiology, Duke University School of Medicine, Duke University Medical Center (J.N.H.), Durham Veterans Affairs Health Care System (Y.S.B., R.A.S., A.B.), Durham, North Carolina.Supplemental Digital Content is available for this article. Direct...
Supraglottic Mass Management in a Pediatric Patient with Proteus Syndrome,Proteus Syndrome is a rare genetic condition that is characterized by vascular, lymphatic malformation and asymmetric overgrowth of skin, bone, central nervous system, and adipose tissue.Sang Le, M.D.; Carl Lo, M.D.; Eugene Kim, M.D. Author NotesFrom the Children's Hospital Los Angeles, Los Angeles, California.Correspondence: Address correspondence to Dr. Le: sale@chla.usc.eduAnesthesiology Newly Published on November 15, 2019....
History of Cranial Nerve–Implanted Stimulators in OtolaryngologyThis article aims to clearly understand the historical development of cranial nerve–implanted stimulators in otolaryngology. The authors also discuss cranial nerve history; initial theory of the functional concept of animal spirit; electrical nerve impulse theory; first electrical otolaryngology cranial nerve stimulation devices; and the development of implanted stimulators.Hypoglossal Nerve (Cranial Nerve XII) StimulationHypoglossal...
Herald Cell: The Gateway to Posterior Tympanotomy—A Cadaveric StudyAbstractPosterior tympanotomy is the avenue to the facial recess of the middle ear from mastoid antrum. The entry into the facial recess in many cases is heralded by a distinct air cell before approaching the facial-chordal plane. The current study was undertaken to determine the prevalence of this 'Herald Cell' in an adult cadaveric population. It was a human cadaveric temporal bone dissection study. The bones were dissected to carry...
Coase and transaction costs reconsidered: the case of the English lighthouse systemAbstractWhat is Coase's understanding of transaction costs in economic theory and history? Our argument in this paper is twofold, one theoretical and the other empirical. First, Coase regarded positive transaction costs as the beginning, not the end, of any analysis of market processes. From a Coasean perspective, positive transaction costs represent a profit opportunity for entrepreneurs to erode such transaction...
Vocal Dose of Preservice Music Therapists, Preservice Music Teachers, and Other Undergraduate StudentsResearchers have studied various populations with high vocal doses and prevalence of related voice disorders. Teachers, singers, and university students are three such populations that have been examined extensively. No studies to date, however, have examined the voice use of music therapists and compared their voice use to these other populations.Treatment Outcomes of Arytenoid Dislocation by Closed...
New SyndromesDe novo loss-of-function KCNMA1 variants are associated with a new multiple malformation syndrome and a broad spectrum of developmental and neurological phenotypesA study published in the Human Molecular Genetics identified eight novel loss-of-function variants of KCNMA1. A phenotypic analysis of the patients carrying the recurrent de novo missense loss-of-function variant revealed a novel syndromic neurodevelopmental disorder associated with severe developmental delay, visceral and...
Treatment Outcomes of Arytenoid Dislocation by Closed Reduction: A Multidimensional EvaluationThis study aimed to investigate the treatment outcomes of arytenoid dislocation by a multidimensional evaluation.Nonselective Laryngeal Reinnervation versus Type 1 Thyroplasty in Patients with Unilateral Vocal Fold Paralysis: A Single Tertiary Centre ExperienceThis study compared the voice outcomes of selected patients with unilateral vocal fold palsy (UVFP) who underwent either nonselective laryngeal reinnervation...
Physician Fertility: A Call to ActionInfertility is more prevalent in female physicians than in the U.S. general population. While pregnancy and its potential medical and career development consequences among physicians have been explored in the literature, infertility and its consequences remain understudied and unaddressed. Fertility issues are important for all physicians hoping to start families, including male physicians, transgender physicians, single physicians, and physicians with same-sex...
International Journal of Molecular Sciences, IJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions... International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial InjuryIJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial Injury International Journal of Molecular Sciences doi: 10.3390/ijms20225728...
International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial InjuryIJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial Injury International Journal of Molecular Sciences doi: 10.3390/ijms20225728 Authors: Daria Shishkova Elena Velikanova Maxim Sinitsky Anna Tsepokina Olga Gruzdeva Leo Bogdanov...
Latest Results for Investigational New DrugsEarly depth of tumor shrinkage and treatment outcomes in non-small cell lung cancer treated using NivolumabSummary Background It would be useful to have criteria for predicting long-term treatment responses to immune checkpoint inhibitors (ICIs). Maximum depth of response correlates with treatment outcomes among patients receiving programmed death protein 1 axis inhibitors for non-small cell lung cancer (NSCLC). We investigated associations between early...
Clinical GeneticsChromatinopathies: a focus on Cornelia de Lange SyndromeAbstract In recent years, many genes have been associated with chromatinopathies classified as "Cornelia de Lange Syndrome‐like". It is known that the phenotype of these patients becomes less recognisable, overlapping to features characteristic of other syndromes caused by genetic variants affecting different regulators of chromatin structure and function. Therefore, Cornelia de Lange Syndrome diagnosis might be arduous due...
Antimicrobial Resistance and Infection Control - Latest ArticlesGradient diffusion antibiogram used directly on bronchial aspirates for a rapid diagnosis of ventilator-associated pneumoniaIn patients with suspected ventilator-associated pneumonia, a rapid etiological diagnosis is crucial as incorrect or delayed treatment in the first few hours leads to a worse prognosis and a higher mortality r...Antimicrobial Resistance and Infection Control - Latest ArticlesThu Nov 14, 2019 02:00Mark above section...
Performance and usability of machine learning for screening in systematic reviews: a comparative evaluation of three toolsWe explored the performance of three machine learning tools designed to facilitate title and abstract screening in systematic reviews (SRs) when used to (a) eliminate irrelevant records (automated simulation) ...Systematic Reviews - Latest Articles02:00Assessing the accuracy of machine-assisted abstract screening with DistillerAI: a user studyWeb applications that employ natural...
Is burn-out finally a disease or not?In May 2019, WHO has stated that burn-out should be considered as a disease in the new version of the International Classification of Diseases (ICD-11). This information was widely disseminated in the news media. However, a few hours later, the international organisation stepped back. All this confusion brings us to that question: what exactly is burn-out? Moreover, should it be considered a disease or not? Freudenberger defined burn-out as 'a state of fatigue...
Generation of solar spicules and subsequent atmospheric heatingSpicules are rapidly evolving fine-scale jets of magnetized plasma in the solar chromosphere. It remains unclear how these prevalent jets originate from the solar surface and what role they play in heating the solar atmosphere. Using the Goode Solar Telescope at the Big Bear Solar Observatory, we observed spicules emerging within minutes of the appearance of opposite-polarity magnetic flux around dominant-polarity magnetic field concentrations....
The relationship between the status and position of third molars and the presence of mandibular angle and condylar fracturesAbstract Introduction The aim of this study was to assess the relationship between the status and position of third molars, and the presence of mandibular angle and/or condylar fractures, in a group of patients treated for mandibular fractures, thus hoping to contribute to the knowledge of potential predictors of these fractures. Methods A retrospective study...Oral and Maxillofacial...
Comparison of wall removal type vs. wall retaining type of decompression for treating large mandibular odontogenic cystsAbstract Objective To evaluate the differences between two types of decompression for treating large mandibular odontogenic cysts. Materials and Methods This retrospective, cohort study included patients who were diagnosed for large mandibular odontogenic cysts from January 2015 to April 2018, and underwent two different types of decompression based on removal or retention of the...
Beyond prospective memory retrieval: Encoding and remembering of intentions across the lifespanPublication date: Available online 14 November 2019Source: International Journal of PsychophysiologyAuthor(s): Alexandra Hering, Nele Wild-Wall, Michael Falkenstein, Patrick D. Gajewski, Katharina Zinke, Mareike Altgassen, Matthias KliegelAbstractCombining behavioral and electrophysiological measures, we investigated the role of memory processes for prospective memory development in three different age...
Transplanted interneurons improve memory precision after traumatic brain injuryNature Communications, Published online: 14 November 2019; doi:10.1038/s41467-019-13170-wThe brain's capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury.Nature Communications - current - nature.com...
Proteomic research in sarcomas - current status and future opportunities.Proteomic research in sarcomas - current status and future opportunities. Semin Cancer Biol. 2019 Nov 10;: Authors: Burns J, Wilding CP, L Jones R, H Huang P Abstract Sarcomas are a rare group of mesenchymal cancers comprising over 70 different histological subtypes. For the majority of these diseases, the molecular understanding of the basis of their initiation and progression remains unclear. As such, limited clinical progress...
Perception of dental and medical teaching faculty regarding mobile dental applicationRicky Pal Singh, Ajithkrishnan Champettil Gopalakrishnapillai, Nagesh Bhat, Amrita PawarJournal of Pharmacy And Bioallied Sciences 2019 11(7):530-539Context: Mobile dental applications Aims: The aim of this study was to assess the attitude and awareness about use of mobile dental apps among the dental and medical teaching faculty of Ghaziabad district. Settings and Design: Cross-sectional questionnaire survey Materials...
Postoperative Venous Thromboembolism after Neurotologic SurgeryJ Neurol Surg BDOI: 10.1055/s-0039-3400223 Objective This study aimed to determine the incidence of postoperative venous thromboembolism (VTE) in adults undergoing neurotologic surgery at a single center. Methods The records of adults undergoing neurotologic surgery from August 2009 to December 2016 at a tertiary care hospital were reviewed for VTE within 30 postoperative days. Particular attention was focused on postoperative diagnosis...
Human Papillomavirus Related Multiphenotypic Sinonasal Carcinoma: Report of a Case with Early and...
Human Papillomavirus Related Multiphenotypic Sinonasal Carcinoma: Report of a Case with Early and Progressive Metastatic DiseaseJ Neurol Surg Rep 2019; 80: e41-e43DOI: 10.1055/s-0039-3399571 Introduction Human papillomavirus (HPV) related multiphenotypic sinonasal carcinoma (HMSC) is a newly described entity. The prognosis of this neoplasm is not well understood, but cases often demonstrate high-grade features and paradoxically indolent behavior. Case Report We present the case of a 65-year-old man...
Correlation between Type of Clefting and the Incidence of Otitis Media among Children with Lip and/or Palate Clefts.Correlation between Type of Clefting and the Incidence of Otitis Media among Children with Lip and/or Palate Clefts. ORL J Otorhinolaryngol Relat Spec. 2019 Nov 13;:1-10 Authors: Mangia LRL, Tramontina B, Tonocchi R, Polanski JF Abstract INTRODUCTION: Otitis media is a frequent condition among children with high morbidity. Orofacial clefts are undoubtedly one of the most well-established...
Secondary Surgical Cytoreduction for Recurrent Ovarian CancerThe American Cancer Society has estimated that in 2019 approximately 22,500 women would be diagnosed with epithelial ovarian, primary peritoneal, or fallopian-tube ("ovarian") cancer, and 14,000 would die. Despite the absence of randomized data showing a survival benefit conferred by primary…The New England Journal of Medicine: Search Results in SurgeryThu Nov 14, 2019 02:00Acute Upper Airway ObstructionAcute upper airway obstruction is...
Dissimilar associations of same metabolic parameters with main chronic noncommunicable diseases (cancer vs some other NCDs)Future Oncology, Ahead of Print.Future OncologyThu Nov 14, 2019 07:01Survival outcomes of mucosal melanoma in the USAFuture Oncology, Ahead of Print.Future OncologyThu Nov 14, 2019 06:30CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathwayThe NSD family of histone lysine methyltransferases have emerged...
Intramolecular photoinitiator induced atom transfer radical polymerization for DNA electrochemical detectionAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN02018G, PaperLigang Ma, Qianrui Liu, Lihe Jian, Shan Ye, Xiao Ke Zheng, Jinming KongA novel electrochemical biosensor was firstly reported to achieve DNA highly sensitive detection based on photoinduced atom transfer radical polymerization (photoATRP). In this work, PNA was applied as capture probes...The content of this RSS Feed (c) The Royal...
Electrospinning Drug Delivery Bandages Directly Onto WoundsElectrospinning is a maturing manufacturing technology that is already being used in medicine to produce unusual materials with novel properties. It involves melting a polymer and extruding it through a narrow nozzle, while an electric field is used to pull and spin the polymer into a very fine mesh. When a biocompatible polymer is used, the printed materials may be applicable for medical applications, as the resulting mesh has an extremely...
Comparative analysis of fresh chondrocytes, cultured chondrocytes and chondroprogenitors derived from human articular cartilagePublication date: Available online 13 November 2019Source: Acta HistochemicaAuthor(s): Elizabeth Vinod, Upasana Kachroo, Soosai Manickam Amirtham, Boopalan Ramasamy, Solomon SathishkumarAbstractIntroductionInterest in chondroprogenitors arose due to their inherent stem cell like properties, and their initial characterization was based on identification of a small percentage...
Risk factors for wheezing in primary health care settings in the tropics The "International Study...
Risk factors for wheezing in primary health care settings in the tropicsThe "International Study of Wheezing in Infants (EISL)", is a cross-sectional, population-based study, based on ISAAC. "(Http // www.isaac.auckland.ac.nz). It uses a validated questionnaire on early wheezing and risk/protective factors.Annals of Allergy, Asthma & ImmunologyThu Nov 14, 2019 02:00Efficacy and Safety of Twice-daily and Once-daily Olopatadine-Mometasone Combination Nasal Spray for Seasonal Allergic RhinitisGSP301...
The effects of cardiorespiratory fitness on executive function and prefrontal oxygenation in older adultsAbstract Reviews on cardiovascular fitness and cognition in older adults suggest that a higher level of cardiorespiratory fitness may protect the brain against the effects of aging. Although studies reveal positive effects of cardiorespiratory fitness on executive function, more research is needed to clarify the underlying mechanisms of these effects in older adults. The aim of the current study...
Reevaluating Norms for Childhood Obstructive Sleep Apnea Brooks DM, Brooks LJ. Reevaluating norms...
Reevaluating Norms for Childhood Obstructive Sleep ApneaBrooks DM, Brooks LJ. Reevaluating norms for childhood obstructive sleep apnea. J Clin Sleep Med. 2019;15(11):1557–1558.The American Academy of Sleep Medicine03:48Seeking the Cause of Restless Legs Syndrome in Chronic Kidney DiseaseMorse AM, Kothare SV. Seeking the cause of restless legs syndrome in chronic kidney disease. J Clin Sleep Med. 2019;15(11):1559–1560.The American Academy of Sleep Medicine03:48Familial Aggregation and Heritability...
International Journal of Molecular Sciences, IJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions... International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial InjuryIJMS, Vol. 20, Pages 5728: Calcium Phosphate Bions Cause Intimal Hyperplasia in Intact Aortas of Normolipidemic Rats through Endothelial Injury International Journal of Molecular Sciences doi: 10.3390/ijms20225728...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,