Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017 Viruses doi: 10.3390/v11110990 Authors: Yassmin Moatasim Ahmed Kandeil Basma Emad Aboulhoda Rabeh El-Shesheny...
Journal of Clinical MedicineJCM, Vol. 8, Pages 1801: A Cross-Sectional Study of Hyponatremia Associated with Acute Central Nervous System InfectionsJCM, Vol. 8, Pages 1801: A Cross-Sectional Study of Hyponatremia Associated with Acute Central Nervous System Infections Journal of Clinical Medicine doi: 10.3390/jcm8111801 Authors: Andy K.H. Lim Sahira Paramaswaran Lucy J. Jellie Ralph K. Junckerstorff Hyponatremia can occur with central nervous system (CNS) infections, but the frequency and severity...
Antioxidants, Vol. 8, Pages 513: Modulation of Reactive Oxygen Species in Health and DiseaseAntioxidants, Vol. 8, Pages 513: Modulation of Reactive Oxygen Species in Health and Disease Antioxidants doi: 10.3390/antiox8110513 Authors: Solomon Habtemariam In diverse living organisms, signaling within the cell, chemical communication between cells or simply the fate of cells to survive or die is largely dependent on the intricate balance of control mechanisms related to reactive oxygen species (ROS)[...]AntioxidantsSat...
Latest Results for Acta Analytica,A Defense of Free-Roaming Cats from a Hedonist Account of Feline Well-beingAbstract There is a widespread belief that for their own safety and for the protection of wildlife, cats should be permanently kept indoors. Against this view, I argue that cat guardians have a duty to provide their feline companions with outdoor access. The argument is based on a sophisticated hedonistic account of animal well-being that acknowledges that the performance of species-normal...
Biomedicine & Pharmacotherapy,Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathwaysPublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Nagla A. El-Shitany, Basma G. EidAbstractCellular inflammation has been recognized as the leading factor in numerous diseases, causing either cell death, organ-specific damage, or genesis of different cancers. Icariin, a flavonol glucoside, extracted from Herba Epimedii,...
Delay of Surgery for DCIS Ups Risk for Invasive Breast CancerEach month delay increases risk for invasive cancer by 1 percent (Source: The Doctors Lounge - Oncology)The Doctors Lounge - Oncology19hMark above section as read The Journal of PhysiologyLocation, location, location: Lessons from airway epithelial anion channelsThe Journal of Physiology20hRegional activation in the human longissimus thoracis pars lumborum muscleKey points •Longissimus activity in the lumbar region was measured using indwelling...
ScienceDirect Publication Sleep Medicine,Utility of the pictorial Epworth sleepiness scale in the adult Down syndrome populationPublication date: Available online 25 October 2019Source: Sleep MedicineAuthor(s): Elizabeth Hill, Donna Fairley, Ewan McConnell, Ian Morrison, Marta Celmina, Serafeim – Chrysovalantis Kotoulas, Renata L. RihaAbstractObjective/BackgroundThe utility of the pictorial Epworth sleepiness scale (pESS) has been assessed by only a few studies in a clinical population. Some of...
Syphilis, congenitalSyphilis, congenital: Infection of a fetus or newborn with syphilis. Syphilis in a fetus can cause deformity, particularly of the long bones, or death. Syphilis infection acquired at birth is also dangerous. See also TORCH infection.MedTerms (TM) is the Medical Dictionary of MedicineNet.com.We Bring Doctors' Knowledge To YouMedTerms Word of the Day4hMark above section as read Movement DisordersDriving genotype treatment options down the right path(way)Movement Disorders12hMark...
Latest Results for Education and Information TechnologiesE-learning readiness of universities in Nigeria- what are the opinions of the academic staff of Nigeria's premier university?Abstract This paper examined the opinions of academic staff of the University of Ibadan Nigeria regarding the preparedness of stakeholders of e-learning in Nigeria for fruitful e-learning experience and action in Nigerian universities. Data was collected from 240 lecturers using a questionnaire. The lecturers considered...
Pediatric Metabolic and Bariatric Surgery: Evidence, Barriers, and Best PracticesSevere obesity among youth is an "epidemic within an epidemic" and portends a shortened life expectancy for today's children compared with those of their parents' generation. Severe obesity has outpaced less severe forms of childhood obesity in prevalence, and it disproportionately affects adolescents. Emerging evidence has linked severe obesity to the development and progression of multiple comorbid states, including...
Journal of Pediatric Surgery,Learning Health Systems and the Future of Clinical ResearchPediatric surgeons are collectively passionate about prioritizing the healthcare needs of children. We contend that this passion is deeply ingrained in how we drive clinical care and influence scientific discovery. Thus, the future of clinical research in our field will be deeply embedded in our history as a "patient-centric" profession. Service to pediatric patients requires an understanding of their needs and...
Hindawi Publishing Corporation,Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical StressBackground. Mechanical stress-induced cardiac remodeling that results in heart failure is characterized by transcriptional reprogramming of gene expression. However, a systematic study of genomic changes involved in this process has not been performed...
Gastrointestinal Endoscopy,Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polypsCold snare polypectomy (CSP) is associated with higher complete resection rates when compared with cold biopsy forceps (CBF) for the removal of small polyps (4-9 mm). This study aimed to evaluate self-reported polypectomy preferences and actual practice patterns among endoscopists at an academic center and to identify factors associated with the use of CSP for...
American Journal of Medical Genetics Part A,Behavioral characterization of dup15q syndrome: Toward meaningful endpoints for clinical trialsAbstract Duplication of 15q11.2‐q13.1 (dup15q syndrome) is one of the most common copy number variations associated with autism spectrum disorders (ASD) and intellectual disability (ID). As with many neurogenetic conditions, accurate behavioral assessment is challenging due to the level of impairment and heterogeneity across individuals. Large‐scale phenotyping...
Psycho-Oncology,Stigma and its correlates in people living with lung cancer: A cross‐sectional study from ChinaAbstract Objectives This study aimed to examine the level of stigma and identify the correlates of stigma among lung cancer patients in China. Methods In total, 283 lung cancer patients were recruited from a tertiary cancer center in China by the convenience sampling method and completed a demographic, disease‐related information and situational characteristics questionnaire and self‐reported...
Psycho-Oncology,Stigma and its correlates in people living with lung cancer: A cross‐sectional study from ChinaAbstract Objectives This study aimed to examine the level of stigma and identify the correlates of stigma among lung cancer patients in China. Methods In total, 283 lung cancer patients were recruited from a tertiary cancer center in China by the convenience sampling method and completed a demographic, disease‐related information and situational characteristics questionnaire and self‐reported...
The Journal of Physiology,Regional activation in the human longissimus thoracis pars lumborum muscleKey points •Longissimus activity in the lumbar region was measured using indwelling electromyography to characterize the territory of its motor units. •The distribution of motor units in the longissimus pars lumborum muscle was mainly grouped into two distinct regions. •Regional activation of the longissimus pars lumborum was also observed during functional tasks involving trunk movements. •The regional...
Clinical ImmunologyImmunomodulatory receptors are differentially expressed in B and T cell subsets relevant to autoimmune diseasePublication date: Available online 25 October 2019Source: Clinical ImmunologyAuthor(s): Katherine A. Murphy, Kartik Bhamidiphati, Samuel J.S. Rubin, Lucas Kipp, William H. Robinson, Tobias V. LanzAbstractInhibitory cell-surface receptors on lymphocytes, often called immune checkpoints, are powerful targets for cancer therapy. Despite their direct involvement in autoimmune...
Journal of NeuroEngineering and Rehabilitation - Cervical trans-spinal direct current stimulation: a modelling-experimental approachTrans-spinal direct current stimulation (tsDCS) is a non-invasive technique with promising neuromodulatory effects on spinal cord (SC) circuitry. Computational studies are essential to guide effective tsDCS pr...Journal of NeuroEngineering and Rehabilitation - Latest Articles17hMark above section as read Journal of Cancer EducationAdvance Care Planning Conversations...
Latest Results for Acta Neuropathologica Communications, Dynein activating adaptor BICD2 controls...
Latest Results for Acta Neuropathologica Communications,Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivoAbstract For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlying this neuronal migration is still poorly understood. The dynein-adaptor protein BICD2 is associated with a spectrum of human neurological...
The Laryngoscope,The prevalence of cognitive impairment in laryngology treatment–seeking patientsObjectives/Hypothesis The incidence of cognitive impairment (CI) in the elderly general population is 10% to 20%. The incidence of CI in the elderly laryngology treatment–seeking population is unknown, and CI may impact decision making for elective medical/surgical treatment and negatively impact the outcome of voice/swallowing therapy. We sought to determine the prevalence of CI in elderly patients...
Cancer Medicine,Real‐world health utility scores and toxicities to tyrosine kinase inhibitors in epidermal growth factor receptor mutated advanced non‐small cell lung cancerReal‐world health utility scores (HUS) in epidermal growth factor receptor mutations (EGFRm) non‐small cell lung cancer outpatients were similar between those treated by first‐ and second‐line tyrosine kinase inhibitors, which were superior to chemotherapy. Treatment‐associated toxicities corresponded to HUS of treatment groups....
Latest Results for Rheumatology and Therapy,Risk of Potential Glucocorticoid-Related Adverse Events in Patients with Giant Cell Arteritis: Results from a USA-Based Electronic Health Records DatabaseAbstract Introduction Oral glucocorticoids (GC) have been the mainstay of treatment for giant cell arteritis (GCA). We estimated the risk and dose–effect relationship of potential GC-related adverse events (AEs) in patients with GCA. Methods This retrospective, observational cohort study utilized data...
Paediatric Renal Synovial Sarcoma: Another Diagnostic Pathological Dilemmahttp://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=13193&channel-name=Indian+Journal+of+Surgical+Oncology5mPeriampullary Carcinoma Complicated by a Transpancreatic Hepatomesenteric Trunk—a Case Report of an Extremely Rare Vascular Anomalyhttp://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=13193&channel-name=Indian+Journal+of+Surgical+Oncology1hMark above...
ScienceDirect Publication: American Journal of Infection Control,Evaluation of a benzalkonium chloride hand sanitizer in reducing transient <em>Staphylococcus aureus</em> bacterial skin contamination in health care workersPublication date: Available online 25 October 2019Source: American Journal of Infection ControlAuthor(s): Sidney Bondurant, Tanya McKinney, Liza Bondurant, Lisa FitzpatrickBackgroundThis study was performed to evaluate the effectiveness of a new commercially available...
Latest Results for Applied Microbiology and Biotechnology,Amelioration of TMAO through probiotics and its potential role in atherosclerosisAbstract Atherosclerosis is a major cause of mortalities and morbidities worldwide. It is associated with hyperlipidemia and inflammation, and become chronic by triggering metabolites in different metabolic pathways. Disturbance in the human gut microbiota is now considered a critical factor in the atherosclerosis. Trimethylamine-N-oxide (TMAO) attracts attention...
Oral and Maxillofacial Surgery,Implant prognosis in irradiated versus non-irradiated nasal, orbital and auricular sitesPublication date: Available online 26 October 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): M.A. ElKhashab, I.A.W. Radi, A.H. ElkhademAbstractThe purpose of this systematic review was to evaluate implant survival in irradiated nasal, auricular, orbital sites and to compare them with non-irradiated respective sites. Four electronic databases and seven...
Otolaryngology-Head and Neck Surgery,Surgery for adult laryngeal papillomatosisPublication date: Available online 26 October 2019Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Adi Primov-Fever, Ory MadgarRecurrent laryngeal papillomatosis is a viral (human papillomavirus) disease that causes the growth of epithelial verrucous lesions. Patients with laryngeal papillomatosis undergo multiple surgeries due to the tendency of the lesions to reoccur and cause recurrent...
Perioperative Acute Kidney Injury ,Sam D. Gumbert, M.D.; Felix Kork, M.D., M.Sc.; Maisie L. Jackson, M.D.; Naveen Vanga, M.D.; Semhar J. Ghebremichael, M.D.; et alChristy Y. Wang, M.D.; Holger K. Eltzschig, M.D., Ph.D. Author NotesFrom the Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas (S.D.G., M.L.J., N.V., S.J.G., C.Y.W., H.K.E.); and the Department of Anesthesiology, Rheinisch-Westfälische Technische Hochschule Aachen...
Verrucous dysplasia or verrucous hyperplasia: Clarity in terminology,Author links open overlay panelAakrutiShahRajiv S.DesaiPankajShirsatShivaniBansalPoojaPrasadDepartment of Oral Pathology, Nair Hospital Dental College, Mumbai 400008, IndiaReceived 25 September 2019, Revised 9 October 2019, Accepted 21 October 2019, Available online 26 October 2019.Show lesshttps://doi.org/10.1016/j.oraloncology.2019.104457Get rights and contentHighlights•Clinicians should be aware that verrucous hyperplasia can...
Acute Kidney Injury after Surgery: Where Does the Journey Lead?Simon Gelman, M.D., Ph.D., F.A.N.Z.C.A. Author NotesFrom the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts.Accepted for publication September 26, 2019.Correspondence: Address correspondence to Dr. Gelman: sgelman@bwh.harvard.eduAnesthesiology Newly Published on October 25, 2019. doi:10.1097/ALN.0000000000003027For decades acute kidney injury has been recognized as one...
Usability Assessment of an Electronic Handoff Tool to Facilitate and Improve Postoperative Communication Between Anesthesia and Intensive Care Unit StaffThe handoff or handover is the exchange of pertinent medical information from one provider to another. Inadequate handoff communication between healthcare providers can negatively impact patient outcomes. In an effort to improve handoff communication, many studies have developed and evaluated the use of a handoff tool such as a handoff checklist...
Beyond atrial septal defect closure, it is time to start seriously considering closing ventricular septal defects with devicesPurpose of the review The purpose of this review is to discuss the history and current state of transcutaneous device closure of ventricular septal defects. Recent findings Newer devices and techniques have expanded the role of transcutaneous device closure of ventricular septal defects. Device closure of ventricular septal defects is a mainstay of therapy in many parts of...
Exercise and lifestyle changes in pediatric asthmaPurpose of review The purpose of this review is to discuss the most recent studies on lifestyle interventions in pediatric asthma. We include studies on physical activity and exercise, sedentary time, nutrition, behavioral therapy and the role of schools. Recent findings Several small studies in children with asthma suggest that exercise interventions can improve aerobic fitness, asthma symptoms or control and quality of life. Existing evidence supports...
Systemic and breath biomarkers for asthma: an updatePurpose of review Finding suitable biomarkers to phenotype asthma, identify individuals at risk of worsening and guide treatment is highly prioritized in asthma research. We aimed to provide an analysis of currently used and upcoming biomarkers, focusing on developments published in the past 2 years. Recent findings Type 2 inflammation is the most studied asthma mechanism with the most biomarkers in the pipeline. Blood eosinophils and fractional...
Increasing Students' Activity in Physical Education: Results of the SELF-FIT TrialPurpose To examine the effects of the SELF-FIT intervention on students' moderate-to-vigorous physical activity (MVPA) and motivation in physical education (PE). Methods In a clustered randomized controlled trial, 667 students (mean age = 14.4 years, SD = 0.78) from 26 schools (i.e., clusters) were randomized into either an experimental group or a wait-list control group. Students in the experimental group received...
Promoting Parent Partnership in Developmentally Supportive Care for Infants in the Pediatric Cardiac Intensive Care UnitBackground: Limited opportunities for parents to care for their critically ill infant after cardiac surgery can lead to parental unpreparedness and distress. Purpose: This project aimed to create and test a bedside visual tool to increase parent partnership in developmentally supportive infant care after cardiac surgery. Methods: The Care Partnership Pyramid was created by a multidisciplinary...
An obscure case of using apixaban anti-Xa levels in a morbidly obese patient who was nil per os with enterocutaneous fistulaApixaban anti-Xa levels have been introduced to monitor apixaban activity. Presented is a fundamental use of anti-Xa monitoring in questionable absorption in enterocutaneous fistula. A 57-year-old morbidly obese male (150 kg, BMI 42.5) presented to the emergency department with deep venous thromboses and pulmonary embolisms. He also had high-output enterocutaneous fistula managed...
Operative Techniques in Otolaryngology - Head and Neck Surgery via MedWorm.com , Robotics in laryngeal surgeryIn conclusion, TORS can be a valuable tool in surgery for adult benign laryngeal masses. (Source: Operative Techniques in Otolaryngology Head and Neck Surgery)Operative Techniques in Otolaryngology - Head and Neck Surgery via MedWorm.com1dOpen surgical approach to laryngoceles and saccular cystsPublication date: Available online 24 October 2019Source: Operative Techniques in Otolaryngology-Head...
Journal of Otolaryngology - Head and Neck Surgery,Pathological margins and advanced cutaneous squamous cell carcinoma of the head and neckThe recommended treatment for cutaneous squamous cell cancer (CuSCC) of the head and neck is Mohs surgical excision or wide local excision. Excision is recommended to a gross surgical margin of 4–6 mm however ...Journal of Otolaryngology - Head and Neck Surgery11hImpact of marginalization on tobacco use in individuals diagnosed with head and neck CancerConsiderable...
Annals of Indian Academy of Neurology : Risperidone-induced tardive akathisia: A rare antipsychotic side effect with management issuesBiswa Ranjan Mishra, Rajeev Ranjan, Debadatta Mohapatra, Santanu NathAnnals of Indian Academy of Neurology 2019 22(4):499-501 Akathisia is a movement disorder, a common extrapyramidal side effect that has been reported to occur primarily with antipsychotics and some neurological conditions. It is manifested by a subjective feeling of inner restlessness along with...
Food Safety News,Belgian Listeria infections linked to Dutch outbreakTwo people in Belgium have been infected with the same type of Listeria behind an outbreak in the Netherlands with European agencies investigating illnesses in other countries. Belgian media cited a report from Sciensano, the Belgian Institute for Health, and agency officials confirmed to Food Safety News that the details were correct while directing us to the Agency for Health and Care (Zorg en gezondheid). The two people that...
The Laryngoscope,What is the optimal duration of antibiotic prophylaxis in clean‐contaminated head and neck surgery?The Laryngoscope3hPrevalence of Vocal Fold Pathologies Among First‐Year Singing Students Across GenresObjectives/Hypothesis The purpose of the study was to compare the prevalence of vocal fold pathologies among first‐year singing students from the classical, musical theatre, and contemporary commercial music (CCM) genres. Study Design Prospective cohort study. Methods Videostroboscopic...
Head & Neck,Degree of technical difficulty of thyroidectomy for autoimmune thyroid diseaseAbstract Background Our goal was to elucidate the differences in degree of technical difficulty of thyroidectomy in patients with autoimmune thyroid diseases. Methods Charts of adult patients who had undergone thyroidectomy were reviewed. Patients with Hashimoto's Thyroiditis (HT) or Graves' Disease (GD) were individually compared to a control group of patients with early stage malignancy or goiter. Results...
Αλλεργία ή κρύωμα; – Οι ενδείξεις που θα σας βοηθήσουν να καταλάβετεΕίναι εύκολο να πιστέψουμε ότι το φτέρνισμα και η μύτη που 'τρέχει' είναι ενδείξεις κρυώματος. Πόσο σίγουροι όμως μπορεί να είμαστε ότι δεν πρόκειται για αλλεργία; Οι παρακάτω διαφορές μας βοηθούν στο να κάνουμε σωστά το διαχωρισμό και να καταλάβουμε για ποιο από τα δύο πρόκειται. Ο βήχας είναι ξηρός. Τα συμπτώματα του λαιμού είναι δυσκολότερα στο να τα καταλάβουμε, αλλά υπάρχει μία διαφορά. Αν βήχουμε φλέγμα, μάλλον είναι κρύωμα....
Ολιγοθερμιδικές γλυκαντικές ύλες και εγκυμοσύνηΗ πηγή του κειμένου που ακολουθεί είναι το pdf "Ολιγοθερµιδικές Γλυκαντικές Ύλες, Ένας Ασφαλής Σύµµαχος στη ∆ιατροφή των Ατόµων µε ∆ιαβήτη", το οποίο έχει αναρτηθεί στο site της ΕΔΕ (Ελληνική Διαβητολογική Εταιρεία). Η κατανάλωση των εγκεκριμένων ολιγοθερμιδικών γλυκαντικών εντός των ορίων της αποδεκτής ημερήσιας πρόσληψης (ADI), είναι ασφαλής και στη διάρκεια της εγκυμοσύνης. Επιστημονικές κοινότητες στην Ευρώπη και σε ολόκληρο τον κόσμο έχουν πραγματοποιήσει...
ScienceDirect Publication: Revista Española de Medicina Nuclear e Imagen Molecular , Segmentación...
ScienceDirect Publication: Revista Española de Medicina Nuclear e Imagen Molecular, Segmentación de gliomas con PET/TC con <sup>18</sup>F-fluorocolina. Estudio multiaproximaciónPublication date: Available online 24 October 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): A.M. García Vicente, J. Pérez-Beteta, G.A. Jiménez Londoño, M. Amo-Salas, F.J. Pena Pardo, M. Villena Martín, J.M. Borrás Moreno, Á. Soriano CastrejónResumenObjetivoEl objetivo fue doble,...
Medical News Today: What to know about heart murmursIn this article, we discuss different types of heart murmur, what causes them, and when they could be serious. We also discuss some treatment options.Featured Health News from Medical News Today11hMedical News Today: Everything you need to know about ACE inhibitorsACE inhibitors are a popular treatment for high blood pressure and other cardiovascular conditions. Read on to learn about the effectiveness of ACE inhibitors and the different types available....
European Journal of Cancer,A systematic literature review and network meta-analysis of effectiveness and safety outcomes in advanced melanomaPublication date: December 2019Source: European Journal of Cancer, Volume 123Author(s): Margreet G. Franken, Brenda Leeneman, Maria Gheorghe, Carin A. Uyl-de Groot, John B.A.G. Haanen, Pieter H.M. van BaalAbstractBackgroundAlthough a myriad of novel treatments entered the treatment paradigm for advanced melanoma, there is lack of head-to-head evidence. We conducted...
ClinicalTrials,Sintilimab and Nab-paclitaxel in Second-line Treatment of Advanced Gastric or Gastro-oesophageal Junction AdenocarcinomaCondition: Advanced Gastric and Gastro-esophageal Junction AdenocarcinomaIntervention: Drug: sintilimabSponsors: Chinese Academy of Medical Sciences; Chinese PLA General Hospital; Beijing Friendship Hospital; Beijing HospitalNot yet recruitingClinicalTrialsFri Oct 25, 2019 15:58Mark above section as read Journal of Human EvolutionPelvic shape variation...
Magnetic Resonance Imaging,Channel-combination method for phase-based |B<sub>1</sub><sup>+</sup>| mapping techniquesPublication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Yunyu Gao, Jijun Han, Yurong Zhu, Jiajia Wang, Xinhua Wei, Xuegang XinAbstractPurposeThe aim of this study was to propose a channel combination method for |B1+| mapping methods using phase difference to reconstruct |B1+| map.Theory and methodsPhase-based |B1+| mapping methods...
Respiratory Care current issue, Noninvasive Diagnostics in the Emergency Department: Just Because...
Respiratory Care current issue,Noninvasive Diagnostics in the Emergency Department: Just Because We Can Doesn't Mean We ShouldRespiratory Care current issueFri Oct 25, 2019 17:34The Effects of Temperature on Lung FunctionRespiratory Care current issueFri Oct 25, 2019 17:34Mark above section as read Behavioural Brain ResearchCornel Iridoid Glycoside Improves Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion via Activating PI3K/Akt/GSK-3β/CREB Pathway in RatsPublication date: Available...
Impact of Home Oxygen Therapy on the Level of Physical Activities in Daily Life in Subjects With COPD: BACKGROUND:Chronic hypoxemia in patients with COPD is a limiting factor that is associated with disease progression and significantly contributes to decreased physical activity. Although correction of hypoxemia results in physiological improvements, oxygen therapy may be related to social isolation and inactivity. However, few studies have objectively investigated the level of physical activity...
bioRxiv Subject Collection: Evolutionary Biology,"And if you gaze long into an abyss, the abyss gazes also into thee": four morphs of Arctic charr adapting to a depth-gradient in Lake Tinnsjoen [NEW RESULTS]BackgroundThe origin of species is a central topic in biology aiming at understanding mechanisms, level and rate of diversification. Ecological speciation is an important driver in adaptive radiation during post-glacial intra-lacustrine niche diversification in fishes. The Arctic charr Salvelinus...
JoVE: Journal of Visualized Experiments,An Experimental Paradigm for Measuring the Effects of Ageing on Sentence ProcessingHere, we present a protocol to examine the age-related decline in sentence processing using a maze task that allowed us to localize the processing difficulty at each word of the sentences during reading.JoVE: Journal of Visualized ExperimentsFri Oct 25, 2019 22:00Absolute Quantification of Cell-Free Protein Synthesis Metabolism by Reversed-Phase Liquid Chromatography-Mass SpectrometryHere,...
Latest Results for Investigational New Drugs,Phase I study of the mTOR inhibitor everolimus in combination with the histone deacetylase inhibitor panobinostat in patients with advanced clear cell renal cell carcinomaSummary Background Preclinical studies suggested synergistic anti-tumor activity when pairing mTOR inhibitors with histone deacetylase (HDAC) inhibitors. We completed a phase I, dose-finding trial for the mTOR inhibitor everolimus combined with the HDAC inhibitor panobinostat in advanced...
Head and Neck,Neoadjuvant PD-1 immune checkpoint blockade reverses functional immunodominance among tumor-antigen specific T cells.Related ArticlesNeoadjuvant PD-1 immune checkpoint blockade reverses functional immunodominance among tumor-antigen specific T cells. Clin Cancer Res. 2019 Oct 23;: Authors: Friedman J, Moore EC, Zolkind P, Robbins Y, Clavijo PE, Sun L, Greene S, Morisada MV, Mydlarz WK, Schmitt N, Hodge JW, Schreiber H, Van Waes C, Uppaluri R, Allen C Abstract PURPOSE: Surgical resection...
pubmed: sleep apnea,Employer-Mandated Obstructive Sleep Apnea Treatment and Healthcare Cost Savings among Truckers.Employer-Mandated Obstructive Sleep Apnea Treatment and Healthcare Cost Savings among Truckers. Sleep. 2019 Oct 24;: Authors: Burks SV, Anderson JE, Panda B, Haider R, Ginader T, Sandback N, Pokutnaya D, Toso D, Hughes N, Haider HS, Brockman R, Toll A, Solberg N, Eklund J, Cagle M, Hickman JS, Mabry E, Berger M, Czeisler CA, Kales SN Abstract OBJECTIVE: To evaluate the effect of an...
Rare Cancers,[Urinary tract hemangiopericytoma treated with radical surgery and neoadjuvant chemotherapy. Report of two cases.]Related Articles[Urinary tract hemangiopericytoma treated with radical surgery and neoadjuvant chemotherapy. Report of two cases.] Arch Esp Urol. 2019 Sep;72(7):705-709 Authors: García-Ibáñez J, Cayuelas-Rubio C, Durán-Rivera A, Mitjana-Biosca S, Monzó-Cataluña A, Ramos-de-Campo M, Sánchez Ballester F, López-Alcina E Abstract OBJECTIVE: Hemangiopericytoma is a tumor of vascular...
pubmed: "cell physiol bioche...Dicer Sequencing, Whole Genome Methylation Profiling, mRNA and smallRNA Sequencing Analysis in Basal Cell Carcinoma.Dicer Sequencing, Whole Genome Methylation Profiling, mRNA and smallRNA Sequencing Analysis in Basal Cell Carcinoma. Cell Physiol Biochem. 2019;53(5):760-773 Authors: Sand M, Bromba A, Sand D, Gambichler T, Hessam S, Becker JC, Stockfleth E, Meyer T, Bechara FG Abstract BACKGROUND/AIMS: Perturbations in the expression of microRNAs (miRNAs) and their maturing...
pubmed: "j cell physiol"[jou...Colon cancer therapy by focusing on colon cancer stem cells and their tumor microenvironment.Colon cancer therapy by focusing on colon cancer stem cells and their tumor microenvironment. J Cell Physiol. 2019 Oct 24;: Authors: Jahanafrooz Z, Mosafer J, Akbari M, Hashemzaei M, Mokhtarzadeh A, Baradaran B Abstract Despite many advances and optimization in colon cancer treatment, tumor recurrence and metastases make the development of new therapies necessary. Colon cancer...
Human Pathology,<em>RUNX2</em> (6p21.1) amplification in osteosarcomaPublication date: Available online 25 October 2019Source: Human PathologyAuthor(s): Sounak Gupta, Tatsuo Ito, Deepu Alex, Chad M. Vanderbilt, Jason C. Chang, Nasrin Islamdoust, Yanming Zhang, Khedoudja Nafa, John Healey, Marc Ladanyi, Meera R. HameedSummaryPrior cytogenetic profiling of osteosarcomas has suggested that amplifications at the 6p12–21 locus are relatively common alterations in these tumors. However, these...
Annals of Indian Academy of Neurology : Comorbidities and long-term outcomes in a cohort with myasthenic crisis: Experiences from a tertiary care centerAjith Sivadasan, Mathew Alexander, Sanjith Aaron, Vivek Mathew, Shalini Nair, Karthik Muthusamy, AT Prabhakar, Rohit N Benjamin, Atif Shaikh, Gideon RynjahAnnals of Indian Academy of Neurology 2019 22(4):464-471 Introduction: There is scarce literature regarding the clinical course, comorbidities and long-term outcomes after myasthenic crisis (MC)....
RNA In Advance,An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21 [Article]DDX21 is a newly discovered RNA G-quadruplex (rG4) binding protein with no known biological rG4 targets. In this study we used label-free proteomic MS/MS to identify 26 proteins that are expressed at significantly different levels in cells expressing wild type DDX21 relative to an rG4 binding deficient DDX21 (M4). Data are available via ProteomeXchange with identifier PXD013501.From this list we validate...
Oncoimmunology,Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma.Related ArticlesStaphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma. Oncoimmunology. 2019;8(11):e1641387 Authors: Blümel E, Willerslev-Olsen A, Gluud M, Lindahl LM, Fredholm S, Nastasi C, Krejsgaard T, Surewaard BGJ, Koralov SB, Hu T, Persson JL, Bonefeld CM, Geisler C, Iversen L, Becker JC,...
bioRxiv Subject Collection: Evolutionary Biology,Trade-offs and selection conflicts in hybrid poplars indicate the stomatal ratio as an important trait regulating disease resistance [NEW RESULTS]Natural selection can remove maladaptive genotypic variance from populations, leaving reduced phenotypic variation as a signal of its action. Hybrid populations offer a unique opportunity to study phenotypic variance before selection purifies it, as these populations can have increased genotypic and phenotypic...
International Journal of Cancer , Benserazide is a novel inhibitor targeting PKM2 for melanoma treatmentThe M2 splice isoform of pyruvate kinase (PKM2) is a key enzyme for generating pyruvate and ATP in the glycolytic pathway, whereas the role of PKM2 in tumorigenesis remains a subject of debate. In this study, we found PKM2 is highly expressed in melanoma patients and the malignance is positively corelated with high PKM2 activity and glycolytic capability in melanoma cells. Suppression of PKM2...
Nanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction...Nanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction Solar Cells by Applying a Spectral Conversion Layer Containing Eu-Doped and Yb/Er-Doped PhosphorsNanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction Solar Cells by Applying a Spectral Conversion Layer Containing Eu-Doped and Yb/Er-Doped Phosphors Nanomaterials doi: 10.3390/nano9111518...
Nanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction...Nanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction Solar Cells by Applying a Spectral Conversion Layer Containing Eu-Doped and Yb/Er-Doped PhosphorsNanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction Solar Cells by Applying a Spectral Conversion Layer Containing Eu-Doped and Yb/Er-Doped Phosphors Nanomaterials doi: 10.3390/nano9111518...
Nanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction...Nanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction Solar Cells by Applying a Spectral Conversion Layer Containing Eu-Doped and Yb/Er-Doped PhosphorsNanomaterials, Vol. 9, Pages 1518: Enhancing Photovoltaic Performance of GaAs Single-Junction Solar Cells by Applying a Spectral Conversion Layer Containing Eu-Doped and Yb/Er-Doped Phosphors Nanomaterials doi: 10.3390/nano9111518...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,