Antibodies against ARHGDIB and ARHGDIB gene expression associate with kidney allograft outcomeBackground. The impact of donor-specific anti-HLA antibodies (DSA) on antibody-mediated rejection (AMR) and kidney allograft failure is well established. However, the relevance of non-HLA antibodies remains unclear. Methods. We investigated 13 pretransplant non-HLA antibodies and their association with histology of AMR (AMRh) and kidney allograft failure. We included single kidney recipients (N=203) with...
09:24
Pulmonary Artery/Vein Separation Using Single-Phase Computed Tomography: Feasibility and the Influence of Patient Characteristics on Vessel EnhancementPurpose: The purpose of this article was to verify the usefulness and feasibility of a single-phase scan for pulmonary artery/vein separation using a bolus-tracking technique and to evaluate the influence of patient characteristics on differentiation of computed tomography (CT) values between arteries and veins. Material and Methods: A total of 79...
09:23
Expression of maspin tumor suppressor and mTOR in laryngeal carcinomaAuthor links open overlay panelGinoMarioniaGiancarloOttavianoaAndreaLovatobLeonardoFranzaLuigiaBandolinaGiacomoControaLucianoGiacomellicLaraAlessandrinicRobertoStramaredCosimode FilippiscStellaBlandamuracaDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, ItalybDepartment of Neuroscience DNS, Audiology Unit, University of Padova, Treviso, ItalycDepartment of Medicine DIMED, University of Padova,...
09:23
Provider Consensus on Candidate Protective and Risk Factors for Adverse Psychosocial Outcomes Following Discharge From a PICU: A Modified Delphi StudyObjectives: Pediatric palliative care promotes interdisciplinary, family-centered care when children are faced with diagnoses threatening length and/or quality of life. A significant knowledge gap remains in how to best match pediatric palliative care resources to palliate the psychosocial impact of a PICU admission. This study was designed to identify...
09:22
Multi-frequency Electrocochleography Measurements can be Used to Monitor and Optimize Electrode Placement During Cochlear Implant SurgeryObjective: To report the use of multi-frequency intra-cochlear electrocochleography (ECOG) in monitoring and optimizing electrode placement during cochlear implant surgery. An acoustic pure tone complex comprising of 250, 500, 1000, and 2000 Hz was used to elicit ECOG, or more specifically cochlear microphonics (CMs), responses from various locations in the cochlea....
09:22
Sexual Abuse and Future Mental Health Hospitalization in a Swedish National Sample of Men Who Use OpioidsObjective: Experiences of trauma, specifically sexual abuse, have been linked to both mental health and substance use disorders. This study used 14 years of Swedish health registry data to select a sample of adult men who reported frequent opioid use and assessed if those with a self-reported history of sexual abuse had a higher likelihood of hospitalization for a mental health disorder. Methods:...
09:21
The Importance of Imaging Informatics and Informaticists in the Implementation of AIPublication date: Available online 19 October 2019Source: Academic RadiologyAuthor(s): Tessa S. CookImaging informatics is critical to the success of AI implementation in radiology. An imaging informaticist is a unique individual who sits at the intersection of clinical radiology, data science, and information technology. With the ability to understand each of the different domains and translate between the experts...
09:21
Serum uric acid and fatal myocardial infarction: detection of prognostic cut-off values: The URRAH (Uric Acid Right for Heart Health) studyObjective: The Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension conceived and designed an ad-hoc study aimed at searching for prognostic cut-off values of serum uric acid (SUA) in predicting fatal myocardial infaction (MI) in women and men. Methods: The URic acid Right for heArt Health study is a nationwide, multicentre,...
09:20
Myths about breastfeedingHussein KouraAl-Azhar Assiut Medical Journal 2019 17(2):109-113Breastfeeding is an unparalleled way of providing ideal food for healthy growth and development of the infant through its unique biological and emotional influences. WHO recommends exclusive breastfeeding for the first 6 months of an infant's life, with continued breastfeeding and complementary feeding introduced after the first 6 months up to the age of 2 years. Many factors affect breastfeeding, and they can...
09:20
Pain monitor: reality or fantasy in ambulatory patientsPurpose of review In an unconscious patient, there can be significant challenges to monitoring nociception and proper dosing of analgesic medications. The traditional measures of intraoperative nociception have poor sensitivity and specificity with little predictive value in postoperative outcomes such as postoperative pain, opioid-induced side effects, length of stay or incidence of opioid use disorder. To date, several monitoring modalities...
09:20
Does Repeated Painful Stimuli Change Cerebral Near-infrared Spectroscopy Response in Healthy Term Large for Gestational Age Newborns?Objective: To evaluate the effect of repeated painful stimuli on short-term pain response in healthy, term, large for gestational age (LGA) newborns by measuring the regional cerebral oxygen saturation (rScO2), behavioral and physiological responses. Methods: We compared term LGA infants who received repeated painful stimuli (study group) to term, appropriate for gestational...
09:19
Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide Into Adipose Tissue During SepsisObjectives: Obese patients have lower sepsis mortality termed the "obesity paradox." We hypothesized that lipopolysaccharide, known to be carried within lipoproteins such as very low density lipoprotein, could be sequestered in adipose tissue during sepsis; potentially contributing a survival benefit. Design: Retrospective analysis. Setting: University research laboratory. Subjects and Patients: Vldlr...
09:19
Myocardial Phosphodiesterases and their Role in cGMP RegulationCyclic nucleotide phosphodiesterases comprise an 11-member superfamily yielding near 100 isoform variants that hydrolyze cAMP or cGMP to their respective 5'-monophosphate form. Each plays a role in compartmentalized cyclic nucleotide signaling, with varying selectivity for each substrate, and conveying cell and intracellular specific localized control. This review focuses on the five PDEs expressed in the cardiac myocyte capable of hydrolyzing...
09:18
Bronchoscopy for Chronic Unexplained Cough: Use of Biopsies and Cultures Increase Diagnostic YieldBackground: Prior studies assessing the diagnostic utility of bronchoscopy for chronic unexplained cough have focused primarily on identifying endobronchial anomalies to determine chronic cough etiology. On the basis of our institutional experience, expanding bronchoscopy to include cultures and biopsies can considerably increase its diagnostic yield for identifying the etiology of chronic unexplained...
09:18
Mixing-based inhibitor screening in haemophilia A: challenges in interpretationInhibitor development in haemophilia A patients is a dreaded complication of factor VIII (FVIII) replacement therapy. With increasing use of FVIII replacement therapy, there is an imperative need for cost-effective and standardized screening. To evaluate the efficacy of mixing-based inhibitor screening (MBIS) in the detection of FVIII inhibitors and to assess the best cut-off values for MBIS. Forty inhibitor positive and...
09:17
Vortioxetine-Related Call–Fleming SyndromeNo abstract availableTreatment Failures of Direct Oral AnticoagulantsBackground: Use of direct oral anticoagulants (DOACs) has increased over the years, because they have become a safe and effective alternative to the Vitamin-K antagonists in various clinical scenarios. With their increased use, reports have emerged describing their failure. Study Question: What are the patient characteristics and clinical settings in which DOAC treatment failure manifests?...
09:17
Clinical outcomes post transition to adult services in young adults with perinatally acquired HIV infection: mortality, retention in care, and viral suppressionObjective: Adolescence is the only age group globally where HIV associated mortality is rising, with poorer outcomes at all stages of the care cascade compared to adults. We examined post-transition outcomes for young adults living with perinatal HIV (YAPaHIV). Design: Retrospective cohort analysis. Setting: A tertiary Youth Friendly Service...
09:16
Droplet digital polymerase chain reaction offers an improvisation over conventional immunohistochemistry and fluorescent in situ hybridization for ascertaining Her2 status of breast cancerMoushumi Suryavanshi, Jiten Jaipuria, Anurag Mehta, Dushyant Kumar, Manoj Kumar Panigrahi, Haristuti Verma, Mumtaz Saifi, Sanjeev Sharma, Simran Tandon, Dinesh Chandra Doval, Bhudev C DasSouth Asian Journal of Cancer 2019 8(4):203-210Background: Droplet digital polymerase chain reaction (DDPCR) is a recent modality...
09:16
CDC Travelers' Health Update , Travelers' diarrhea (TD) is the most common travel-related illness.In otherwise healthy adults, TD is rarely serious or life-threatening, but it can certainly make for an unpleasant trip. Take steps to avoid TD when you travel. Full article.Prevent• Only drink water that you know is safe; otherwise, stick to bottled or boiled drinks. Avoid ice.• Only eat food that is cooked and served hot, peeled by you, or factory-sealed. Self-Treatment• Drink fluids.• Consider...
09:15
The epididymal immune balance: a key to preserving male fertilityAllison Voisin, Fabrice Saez, Joël R Drevet, Rachel GuitonAsian Journal of Andrology 2019 21(6):531-539Up to 15% of male infertility has an immunological origin, either due to repetitive infections or to autoimmune responses mainly affecting the epididymis, prostate, and testis. Clinical observations and epidemiological data clearly contradict the idea that the testis confers immune protection to the whole male genital tract. As a consequence,...
09:10
Interactions of ginseng with therapeutic drugsAuthors:Min-Koo Choi and Im-Sook SongContent type:Review31 August 2019Warburg effect and its role in tumourigenesisAuthors:Maphuti T. Lebelo, Anna M. Joubert and Michelle H. VisagieContent type:Research Article19 August 2019Pifithrin-μ induces necroptosis through oxidative mitochondrial damage but accompanies epithelial–mesenchymal transition-like phenomenon in malignant mesothelioma cells under lactic acidosisAuthors:Yoon-Jin Lee, Kwan-Sik Park, Su-Hak...
09:09
A Common Frame for Formal ImaginationAuthors:Joan Casas-Roma, M. Elena Rodríguez and Antonia HuertasContent type:OriginalPaper15 October 2019A Misdirected Principle with a Catch: Explicability for AIAuthors:Scott RobbinsContent type:Commentary11 October 2019Ethics of AI and Cybersecurity When Sovereignty is at StakeAuthors:Paul TimmersContent type:OriginalPaper21 September 2019The Rhetoric and Reality of Anthropomorphism in Artificial IntelligenceAuthors:David WatsonContent type:Original Article30...
09:08
KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cellsPublication date: 28 January 2020Source: Cancer Letters, Volume 469Author(s): Yingying Tong, Dong Guo, Dong Yan, Chunmin Ma, Fei Shao, Yugang Wang, Shudi Luo, Liming Lin, Jingjing Tao, Yuhui Jiang, Zhimin Lu, Dongming XingAbstractFrequently occurring histone lysine succinylation is a newly identified histone modification that can be...
09:08
Practitioner Perceptions of Evidence-Based Practice in Elite Sport in the United States of AmericaFullagar, HHK, Harper, LD, Govus, A, McCunn, R, Eisenmann, J, and McCall, A. Practitioner perceptions of evidence-based practice in elite sport in the United States of America. J Strength Cond Res 33(11): 2897–2904, 2019—Practitioners' perceptions regarding the use and effectiveness of research evidence in sport is not well understood. The purpose of the present study was to examine practitioners' perceptions...
09:07
Indices of pain variability: a paradigm shiftNo abstract availableAcute neuropathic pain: equivalent or different to chronic neuropathic pain? A call for gathering of scientifically based information on acute neuropathic painNo abstract availableInvestigating intraindividual pain variability: methods, applications, issues, and directionsPain is a dynamic experience subject to substantial individual differences. Intensive longitudinal designs best capture the dynamical ebb and flow of the pain experience...
09:07
Gender Differences and Similarities in Accelerated Nursing Education Programs: Evidence of Success From the New Careers in Nursing ProgramAIM The aim of the study was to examine the profile of male students in accelerated nursing education programs (ANEPs) focusing on key demographic, educational, and outcome variables and compare male and female students on these variables. BACKGROUND Though ANEPs have proliferated over the last two decades, there has been little study of students enrolled in these...
09:06
Parental Attitudes Towards Prenatal Genetic Testing For Sickle Cell DiseaseUptake of prenatal genetic testing (PGT) is low among those with sickle cell disease (SCD). This study evaluated the association of knowledge and attitudes towards prenatal genetic counseling (PGC), awareness of posttesting intervention options and omission bias with attitudes towards PGT. In addition, we explored changes among knowledge, attitudes, and awareness of options following exposure to an educational, clinical vignette...
09:05
The Impact of Hematologic Cancer and Its Treatment on Physical Activity Level and Quality of Life Among Children in Mainland China: A Descriptive StudyBackground The effects of hematologic cancer and its treatment on Chinese children's physical activity level and quality of life (QoL) remain unclear despite numerous studies conducted in Western countries and Hong Kong. Objective The aim of this study was to examine the effects of hematologic cancer and its treatment on the physical activity level...
09:05
Contributors: Clinical Dilemmas and Unresolved Issues in GynecologyNo abstract availableForeword: Clinical Dilemmas and Unresolved Issues in GynecologyNo abstract availableBreast Cancer and the Obstetrician-Gynecologist: A Focus on Screening, Risk Assessment and Treatment of Survivors With Genitourinary Syndrome of MenopauseBecause of conflicting guidelines, providing appropriate breast cancer screening recommendations to our patients has become challenging. Given the high prevalence of genitourinary...
09:04
Magnetic Resonance Imaging for the Follow-up of Treated Thymic Epithelial MalignanciesPurpose: The purpose of this article was to compare magnetic resonance imaging (MRI) depiction of thymic malignancy progression/recurrence with that of computed tomography (CT). Methods: We retrospectively reviewed all surgically treated thymic epithelial malignancy (TEM) patients between 2011 and 2018 who were followed-up with chest CT and MRI. We compared the detection of recurrence and metastatic disease between...
09:04
Adverse Events Associated with Balloon Sinuplasty: A MAUDE Database Analysis: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveBalloon sinuplasty utilization has increased significantly since its introduction over a decade ago. However, the most common associated complications are still unknown. The objective of this study was to analyze adverse events related to balloon sinuplasty.Study DesignRetrospective cross-sectional analysis.SettingFood and Drug Administration's MAUDE database...
Wed Oct 23, 2019 09:50
Surgical Instrument Optimization to Reduce Instrument Processing and Operating Room Setup Time: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveAs health care expenditures rise, novel ways to increase efficiency are sought. The operating room (OR) represents an area where there is opportunity to optimize work flow and supply use. Evidence suggests that instrument redundancy in the OR tends to be high and that direct cost savings can be achieved by "optimizing" surgical trays. The purpose...
Wed Oct 23, 2019 09:49
Five-Year Objective and Subjective Outcomes of Velopharyngeal Surgery for Patients with Obstructive Sleep Apnea: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveTo assess the long-term effects of velopharyngeal surgery on objective and subjective symptoms in patients with obstructive sleep apnea (OSA).Study DesignProspective cohort study.SettingUniversity medical center.Subjects and MethodsEighty-six patients with OSA underwent velopharyngeal surgery, which consisted of revised uvulopalatopharyngoplasty...
Wed Oct 23, 2019 09:49
Clinical Implications of Carcinoma In Situ in Sinonasal Inverted Papilloma: Otolaryngology–Head and Neck Surgery, Ahead of Print. ObjectiveSinonasal inverted papilloma (IP) is a typically benign sinonasal tumor with a tendency to recur and the potential for malignant transformation. Varying degrees of dysplasia may be present, of which carcinoma in situ (CIS) is most advanced. We hereby describe the biological and clinical behavior of IP with CIS (IPwCIS).Study DesignRetrospective cohort.SettingTertiary...
Wed Oct 23, 2019 09:48
Predictors of Occult Lymph Node Metastasis and Prognosis in Patients with cN0 T1–T2 Supraglottic Laryngeal Carcinoma: A Retrospective Study: Background: This work aimed to explore the predictors of lymph node metastasis (LNM) and analyze the prognosis of patients with clinically node-negative (cN0) T1–T2 supraglottic laryngeal carcinoma (SGLC). Methods: Data for 130 patients with cN0 T1–T2 SGLC who initially underwent surgery were retrospectively reviewed. Occult LNM incidence, relevant factors,...
Wed Oct 23, 2019 09:47
Endolymphatic sac decompression and shunt placement: Publication date: September 2019Source: Operative Techniques in Otolaryngology-Head and Neck Surgery, Volume 30, Issue 3Author(s): Sarah E. Mowry, Mark Frilling, Nauman F. Manzoor, Maroun T. Semaan, Cliff A. MegerianEndolymphatic sac decompression and shunting is a nonablative surgical option for patients with intractable Meniere's disease. Sac surgery had a high success rate for vertigo control in this population with 75%-95% of patients experiencing...
Wed Oct 23, 2019 09:46
A case report of severe nasal ischemia from cold agglutinin disease and a novel treatment protocol including HBOT: Cold agglutinin disease (CAD) is a rare condition leading to blood agglutination and autoimmune hemolytic anemia. Cutaneous ischemia resulting from CAD in the head and neck is uncommon. Treatment regimens and ...
Wed Oct 23, 2019 09:45
Food Safety News District's popular Persian restaurant chain is not having a good yearThe Moby Dick House of Kabob, a Persian restaurant chain with two dozen locations in the Washington D.C. area, has had 30 good years, but this is not one of them. Maryland, Virginia and Washington D.C. health departments continue their investigations into Salmonella illnesses likely linked to hummus served at various Moby Dick locations throughout the nation's capital region. Humus production for Moby Dick was...
Wed Oct 23, 2019 09:44
Indian Journal of Ophthalmology : Structural evaluation of preperimetric and perimetric glaucomaGunjan Deshpande, Richa Gupta, Prashant Bawankule, Dhananjay Raje, Moumita ChakarbortyIndian Journal of Ophthalmology 2019 67(11):1843-1849 Purpose: To evaluate diagnostic ability of macular ganglion cell layer–inner plexiform layer (GCL-IPL) for detection of preperimetric glaucoma (PPG) and perimetric glaucoma and comparison with peripapillary RNFL. Methods: Three hundred and thirty seven eyes of 190...
Wed Oct 23, 2019 09:43
Dentistry and Medical Research : Systemic antibiotics in the treatment of periodontitisEsra Guzeldemir-AkcakanatDentistry and Medical Research 2019 7(2):33-33Dentistry and Medical Research : 2014 - 2(2)7hRelevance of hematological parameters in patients with recurrent aphthous stomatitisAlberto Rodriguez-Archilla, Maria BrykovaDentistry and Medical Research 2019 7(2):35-39 Background: Recurrent aphthous stomatitis (RAS) continues to be a very common ulcerative disease of the oral mucosa, affecting...
Wed Oct 23, 2019 09:42
Impact of lumbar interbody fusion surgery on postoperative outcomes in patients with recurrent lumbar disc herniation: Analysis of the US national inpatient sample.Related ArticlesImpact of lumbar interbody fusion surgery on postoperative outcomes in patients with recurrent lumbar disc herniation: Analysis of the US national inpatient sample. J Clin Neurosci. 2019 Oct 17;: Authors: Ye YP, Hu JW, Zhang YG, Xu H Abstract Little information is available on associations between different lumbar interbody...
Wed Oct 23, 2019 09:12
Der Pathologe , Die IgG4-assoziierte ErkrankungZusammenfassung Bei dem als „IgG4-assoziierte Erkrankung" bezeichneten Krankheitsbild handelt es sich um einen potenziell systemischen, chronisch entzündlichen und fibrosierenden Prozess. Unabhängig von der Organmanifestation sind die histologischen Hauptmerkmale ein lymphoplasmazelluläres Infiltrat, eine storiforme Fibrose und eine obliterative Phlebitis. Diese Hauptmerkmale werden jedoch in bestimmten Organen unterschiedlich gewichtet. Wenn mehrere...
Wed Oct 23, 2019 09:11
[Spindle-cell sarcoma in the mandibular area of a 5-year-old Holstein Friesian cow].Related Articles[Spindle-cell sarcoma in the mandibular area of a 5-year-old Holstein Friesian cow]. Tierarztl Prax Ausg G Grosstiere Nutztiere. 2019 Oct;47(5):311-315 Authors: Gaude I, Otzen H, Hoedemaker M, Attig F, Gerhauser I, Hewicker-Trautwein M, Heppelmann M Abstract A 5-year-old German-Holstein cow was presented with a swelling of the head which had been present for 3 months. Clinical examination revealed...
Wed Oct 23, 2019 09:09
Preliminary development of a questionnaire measuring patient views of participation in clinical trialsThis study aimed to develop a questionnaire for measuring patient perceptions of participating in clinical trials. Development was based on earlier research on patient views of involvement in medical care and ...BMC Research NotesMon Oct 21, 2019 03:00Flight muscles degenerate by programmed cell death after migration in the wheat aphid, Sitobion avenaePrevious studies showed that flight muscles degenerate...
Wed Oct 23, 2019 09:08
Postnatal morphological lung development of wild type and CD26/DPP4 deficient rat pups in dependency of LPS exposurePublication date: Available online 22 October 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Wagener Inga, Jungen Meike, von Hörsten Stephan, Stephan Michael, Schmiedl AndreasAbstractBackgroundRodents are born with morphological immature lungs and an intact surfactant system. CD26/DPP4 is a multifactorialtransmembrane integral type II protein, which is involved in physiological...
Wed Oct 23, 2019 09:06
Radiation Molecular Biology.Exam Preparation and Performance Reporting Changes for the American Board of Radiology Radiation Oncology Physics Examination: Results From the ASTRO WorkgroupPublication date: Available online 21 October 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Jay Burmeister, John Buatti, Rachel Jimenez, Samuel Marcrom, Kenneth Olivier, Michael Price, Paul WallnerRadiation Molecular Biology.Tue Oct 22, 2019 14:41"Examinations in Radiation Oncology:...
Wed Oct 23, 2019 09:05
Incidence and Outcomes of Acute Laryngeal Injury After Prolonged Mechanical Ventilation.Related ArticlesIncidence and Outcomes of Acute Laryngeal Injury After Prolonged Mechanical Ventilation. Crit Care Med. 2019 Oct 17;: Authors: Shinn JR, Kimura KS, Campbell BR, Sun Lowery A, Wootten CT, Garrett CG, Francis DO, Hillel AT, Du L, Casey JD, Ely EW, Gelbard A Abstract OBJECTIVES: Upper airway injury is a recognized complication of prolonged endotracheal intubation, yet little attention has been paid...
Wed Oct 23, 2019 09:04
Mometasone absorption in cultured airway epitheliumBackground Topical mometasone is frequently used as an intranasal spray, on drug‐eluting stents, and compounded by specialty pharmacies as a sinus rinse. A typical sinus rinse contains 1.2 mg of mometasone dissolved in 240 mL of buffered saline and is flushed through the sinonasal cavity. The mometasone irrigation rapidly flows to the contralateral sinonasal cavity or the nasopharynx with a contact time on the order of 5 to 10 seconds. However, no...
Wed Oct 23, 2019 09:03
Adjuvant intensity modulated whole-abdominal radiation therapy for high-risk patients with ovarian cancer FIGO stage III: final results of a prospective phase 2 studyTo assess late toxicity, quality of life and oncological outcome after consolidative whole abdominal radiotherapy (WART) following cytoreductive surgery and carboplatin/paclitaxel chemotherapy in high risk pat...Radiation Oncology - Latest ArticlesMon Oct 21, 2019 03:00Mark above section as read Otology & Neurotology Published Ahead-of-PrintThe...
Wed Oct 23, 2019 09:02
Neuro-Oncology , Analysis of intra-operative variables as predictors of 30-day readmission in patients undergoing glioma surgery at a single centerAbstract Purpose Reducing the time from surgery to adjuvant chemoradiation, by decreasing unnecessary readmissions, is paramount for patients undergoing glioma surgery. The effects of intraoperative risk factors on 30-day readmission rates for such patients is currently unclear. We utilized a predictive model-driven approach to assess the impact of intraoperative factors...
Wed Oct 23, 2019 09:01
Cancer Immunology, Immunotherapy , Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinomaAbstract Hepatic stellate cells (HSCs) are important stromal cells and pivotal mediators involved in the pathogenesis and immunosuppression of hepatocellular carcinoma (HCC). The liver has been demonstrated to be a site for accumulation of tumor-induced myeloid-derived suppressor cells (MDSCs). We previously reported that...
Wed Oct 23, 2019 08:59
Facial Plastic Surgery , Clinical Aesthetics of the Nose for Filler InjectionFacial plast Surg 2019; 35: 561-562DOI: 10.1055/s-0039-1696991Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents | Full textFacial Plastic SurgeryTue Oct 22, 2019 02:00Reductive Nasal ProfileplastyFacial plast Surg 2019; 35: 446-457DOI: 10.1055/s-0039-1696653Reductive nasal profileplasty is often the pillar of aesthetic nasal surgery. The surgeon must be...
Wed Oct 23, 2019 08:58
Latest Results for Applied Microbiology and Biotechnology , Biocatalytic production of D- p -hydroxyphenylglycine by optimizing protein expression and cell wall engineering in Escherichia coliAbstract D-p-hydroxyphenylglycine (D-HPG) functions as an intermediate and has important value in antibiotic industries. The high pollution and costs from chemical processes make biotechnological route for D-HPG highly desirable. Here, a whole-cell transformation process by D-hydantoinase(Hase) and D-carbamoylase(Case)...
Wed Oct 23, 2019 08:57
International Journal of Molecular Sciences , IJMS, Vol. 20, Pages 5244: Transcription Factor... International Journal of Molecular Sciences , IJMS, Vol. 20, Pages 5244: Transcription Factor GarWRKY5 Is Involved in Salt Stress Response in Diploid Cotton Species (Gossypium aridum L.)IJMS, Vol. 20, Pages 5244: Transcription Factor GarWRKY5 Is Involved in Salt Stress Response in Diploid Cotton Species (Gossypium aridum L.) International Journal of Molecular Sciences doi: 10.3390/ijms20215244 Authors:...
Wed Oct 23, 2019 08:50
International Journal of Molecular Sciences , IJMS, Vol. 20, Pages 5244: Transcription Factor GarWRKY5 Is Involved in Salt Stress Response in Diploid Cotton Species (Gossypium aridum L.)IJMS, Vol. 20, Pages 5244: Transcription Factor GarWRKY5 Is Involved in Salt Stress Response in Diploid Cotton Species (Gossypium aridum L.) International Journal of Molecular Sciences doi: 10.3390/ijms20215244 Authors: Qi Guo Liang Zhao Xinqi Fan Peng Xu Zhenzhen Xu Xianggui Zhang Shan Meng Xinlian Shen Cotton is...
Wed Oct 23, 2019 08:45
Cancers, Vol. 11, Pages 1616: Epigenetic Reprogramming for Targeting IDH-Mutant Malignant Gliomas...
Cancers, Vol. 11, Pages 1616: Epigenetic Reprogramming for Targeting IDH-Mutant Malignant GliomasCancers, Vol. 11, Pages 1616: Epigenetic Reprogramming for Targeting IDH-Mutant Malignant Gliomas Cancers doi: 10.3390/cancers11101616 Authors: Jong-Whi Park Şevin Turcan Targeting the epigenome has been considered a compelling treatment modality for several cancers, including gliomas. Nearly 80% of the lower-grade gliomas and secondary glioblastomas harbor recurrent mutations in isocitrate dehydrogenase...
Wed Oct 23, 2019 08:43
Antibiotics, Vol. 8, Pages 190: Erratum: Kamiński, M., Łoniewski, I., Marlicz, W. Global Internet...
Antibiotics, Vol. 8, Pages 190: Erratum: Kamiński, M., Łoniewski, I., Marlicz, W. Global Internet Data on the Interest in Antibiotics and Probiotics Generated by Google Trends. Antibiotics 2019, 8(3), 147Antibiotics, Vol. 8, Pages 190: Erratum: Kamiński, M., Łoniewski, I., Marlicz, W. Global Internet Data on the Interest in Antibiotics and Probiotics Generated by Google Trends. Antibiotics 2019, 8(3), 147 Antibiotics doi: 10.3390/antibiotics8040190 Authors: Mikołaj Kamiński Igor Łoniewski Wojciech...
Wed Oct 23, 2019 08:43
The American Journal of Cultural Sociology, Volume 7 (2019)Material culture and the problem of agencyBetween legitimization and popularization: the rise and reception of U.S. cultural products in culture sections of quality European newspapers, 1960–2010AbstractA prominent feature of cultural globalization has been the rising influence of U.S. culture—and American popular culture in particular—worldwide since the mid-20th century. Relatively little is known, however, about the thoroughness, reception,...
Wed Oct 23, 2019 08:40
Increasing prevalence of antibiotic resistance genes in manured agricultural soils in northern ChinaAbstractLand application of manure tends to result in the dissemination of antibiotic resistance in the environment. In this study, the influence of long-term manure application on the enrichment of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in agricultural soils was investigated. All the analyzed eight ARGs (tetA, tetW, tetX, sulI, sulII, ermF, aac(6′)-Ib-cr and blaTEM)...
Wed Oct 23, 2019 08:39
The Respimat ® Soft Mist Inhaler: Implications of Drug Delivery Characteristics for PatientsAbstractSuccessful treatment for respiratory diseases relies on effective delivery of medication to the lungs using an inhalation device. Different inhalers have distinct characteristics affecting drug administration and patient adherence, which can impact clinical outcomes. We report on the development of the Respimat® soft mist inhaler (SMI) and compare key attributes with metered-dose inhalers (MDIs) and...
Wed Oct 23, 2019 08:39
Synthesis, characterization and pharmacological potential of green synthesized copper nanoparticlesAbstractThe phenomenal and astonishing properties and their different application in the field of pharmaceutical made copper nanoparticles (Cu-NPs) to be in the spotlight of the researcher's focus. In the present study, copper nanoparticles were biologically synthesized with the aqueous extract of the flower Millettia pinnata, and their corresponding characteristics were studied using UV–visible spectroscopy,...
Wed Oct 23, 2019 08:39
Biocatalytic production of D- p -hydroxyphenylglycine by optimizing protein expression and cell wall engineering in Escherichia coliAbstractD-p-hydroxyphenylglycine (D-HPG) functions as an intermediate and has important value in antibiotic industries. The high pollution and costs from chemical processes make biotechnological route for D-HPG highly desirable. Here, a whole-cell transformation process by D-hydantoinase(Hase) and D-carbamoylase(Case) was developed to produce D-HPG from DL-hydroxyphenylhydantoin(DL-HPH)...
Wed Oct 23, 2019 08:38
Biologic treatment options for the hip: A narrative reviewThe goal of surgery around the hip is to preserve both acetabular and femoral bone stock and to optimize function, specifically abductor function. Biologic options include allografts, allograft metal composites, and structural grafts that over time incorporate, are durable, and provide bone stock for future reconstruction(s). Reconstructive principles are guided by the defect(s) after tumor surgery, patient factors (age, chemotherapy, comorbid...
Wed Oct 23, 2019 08:38
HypophysenadenomeZusammenfassungAufgrund der Seltenheit klinisch relevanter Hypophysenadenome erfolgt die Diagnosestellung trotz charakteristischer Symptome oft erst im fortgeschrittenen Stadium. Die typischen klinischen Erscheinungsformen werden in dieser Übersichtsarbeit dargestellt. In jüngster Vergangenheit gelang mit dem Nachweis der USP8-Mutation bei Morbus Cushing und des X‑linked-acrogigantism(X-LAG)-Syndroms ein Durchbruch bei der Erforschung molekularer Ursachen von Hypophysenadenomen....
Wed Oct 23, 2019 08:38
Prevalence of Indoor Tanning Among U.S. High School Students from 2009 to 2017AbstractIndoor tanning exposes users to high levels of ultraviolet radiation, increasing skin cancer risk. The risk is greatest for those who begin indoor tanning at a young age. The objective of this study was to assess changes in indoor tanning prevalence over time among U.S. high school students, by sex, age, and race/ethnicity. We used cross-sectional data from the 2009, 2011, 2013, 2015, and 2017 national Youth Risk...
Wed Oct 23, 2019 08:38
Tension measurements in abdominal wall hernia repair: Concept and clinical applicationsPaul L Tenzel, Jordan A Bilezikian, Frederic E Eckhauser, William W HopeInternational Journal of Abdominal Wall and Hernia Surgery 2019 2(4):119-124Tension has always been and remains an important concept in hernia repair. Revolutionary techniques in the field of hernia repair have generally aimed to reduce tension and thereby reduce recurrence rates. Despite the uniformly agreed upon idea that tension is an important...
Wed Oct 23, 2019 08:38
Universal neonatal hearing screening in a tertiary care center in South IndiaRamiya Ramachandran Kaipuzha, Davis Thomas Pulimoottil, Padmanabhan KarthikeyanSaudi Journal of Otorhinolaryngology Head and Neck Surgery 2019 21(2):29-32Objective: The aim of the study is to determine the prevalence of hearing loss among newborn infants and to assess the effectiveness and utility of otoacoustic emission (OAE) as a screening tool to detect hearing impairment in newborns and the relationship between selected...
Wed Oct 23, 2019 08:37
First record of a fossil monkey (Primates, Cercopithecidae) from the Late Pliocene of SerbiaPublication date: December 2019Source: Journal of Human Evolution, Volume 137Author(s): Predrag Radović, Joshua Lindal, Zoran Marković, Sanja Alaburić, Mirjana RoksandicAbstractThe cercopithecid fossil record of the Balkan Peninsula extends from the Late Miocene to the Early Pleistocene, but to date no fossils of non-human primates have been identified in Serbia. Here we report the identification of two primate...
Wed Oct 23, 2019 08:37
Coordinate based meta-analysis of networks in neuroimaging studiesPublication date: 15 January 2020Source: NeuroImage, Volume 205Author(s): C.R. Tench, Radu Tanasescu, C.S. Constantinescu, W.J. Cottam, D.P. AuerAbstractMeta-analysis of summary results from published neuroimaging studies independently testing a common hypothesis is performed using coordinate based meta-analysis (CBMA), which tests for consistent activation (in the case of functional MRI studies) of the same anatomical regions. Using...
Wed Oct 23, 2019 08:37
Patients with Persistently Low MELD-Na Scores Continue to be at Risk of Liver Related DeathBackground: The vast majority of patients with cirrhosis have low Model for End Stage Liver Disease-Sodium (MELD-Na) scores, however the ability for the MELD-Na score to predict patient outcomes at low scores is unclear. Methods: Adult patients in a multicenter, Chicago-wide database of medical records with ICD-9 codes of cirrhosis and without a history of hepatocellular carcinoma were included. Records were...
Wed Oct 23, 2019 08:37
Dyslipidemia and cardiovascular diseases: Science or fairy taleBasil Nwaneri OkeahialamNigerian Journal of Cardiology 2019 16(1):1-4Echocardiographic findings in Nigerian patients with strokeJamila Ado Ya'u, Kamilu Musa Karaye, BN OkeahialamNigerian Journal of Cardiology 2019 16(1):5-10Stroke is the third leading cause of death in several industrial countries and cardio-embolism accounts for 15–30% of ischaemic strokes. Studies investigating associations between echocardiographic parameters and stroke...
Wed Oct 23, 2019 08:37
Pediatric Plasma and Platelet Transfusions on Extracorporeal Membrane Oxygenation: A Subgroup Analysis of Two Large International Point-Prevalence Studies and the Role of Local GuidelinesObjectives: To describe the indications and thresholds for plasma and platelet transfusions for pediatric extracorporeal membrane oxygenation, to compare responses to these transfusions and to describe institutional protocols directing their administration. Design: Subgroup analysis of two prospective, observational...
Wed Oct 23, 2019 08:36
Laryngoscopic techniques modulate anaesthesiologists' perception of halitosis in patients: A randomised controlled trialBACKGROUND Perception of halitosis in patients during intubation is a common and additional stressor for anaesthesiologists and may lead to potential health risks. OBJECTIVES We hypothesised that intubation with videolaryngoscopy could help reduce the anaesthesiologists' perception of patients' oral malodor during intubation. DESIGN Randomised, single-blinded, prospective, controlled...
Wed Oct 23, 2019 08:35
Co-occurrence of Warthin's tumor with oral squamous cell carcinoma – Overlapping risk factors and implicationsAuthor links open overlay panelBhatlawandeHarshada(Postgraduate student)DesaiKarishma Madhusudan(Research Scholar)KaleAlka Dinesh(Principal and Professor)AngadiPunnya(Professor)HallikerimathSeema(Professor)ChibborahRebekah(Postgraduate student)Department of Oral Pathology and Microbiology, KLE VK Institute of Dental Sciences, KLE Academy of Higher Education and Research [KLE University],...
Wed Oct 23, 2019 08:35
Specific challenges in end-of-life care for patients with hematological malignanciesPurpose of review The disease-related burden of patients with hematological malignancies is comparable with patients suffering from solid tumors. Palliative care offers relief from suffering independent of type of disease and prognosis. The prevalence of hematological malignancies is expected to increase in the next 20 years because of better therapeutic options with longer survival and because of the aging population....
Wed Oct 23, 2019 08:35
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,