Survey of Infection Control Precautions for Patients with Severe Combined Immune DeficiencyAbstractSevere combined immune deficiency (SCID) is caused by an array of genetic disorders resulting in a diminished adaptive immune system due to impaired T lymphocytes. In these patients, active infection at the time of hematopoietic transplantation has been shown to increase morbidity and mortality. To prevent transmission of infections in SCID patients, standardized infection control precautions should...
Pigment Cell & Melanoma Research Early View Online Version of Record before inclusion in an issue...
Pigment Cell & Melanoma ResearchEarly ViewOnline Version of Record before inclusion in an issueORIGINAL ARTICLESIsomiRs and tRNA‐derived fragments are associated with metastasis and patient survival in uveal melanomaEric Londin, Rogan Magee, Carol L. Shields, Sara E. Lally, Takami Sato, Isidore RigoutsosVersion of Record online: 16 August 2019LETTERS TO THE EDITORExcimer stamp test distinguishing between nevus depigmentosus and segmental vitiligoJung Min Bae, Sung Hye Eun, Yeong Ho Kim, Ji Hun...
Pediatric DermatologyEarly ViewOnline Version of Record before inclusion in an issueBRIEF REPORTSSuccessful use of topical minoxidil in the treatment of hypotrichosis associated with desmoplakin mutationsMargaret Dowd MD, Nina Antonov MD, Maria Garzon MD, Christine Lauren MDVersion of Record online: 14 August 2019BRIEF REPORTSSubcutaneous dermoid cysts on the eyebrow and neckKoji Nakajima MD, PhD, Ayumi Korekawa MD, PhD, Hajime Nakano MD, PhD, Daisuke Sawamura MD, PhDVersion of Record online: 14...
Physiology of cerebrospinal fluid circulationPurpose of review This article describes the physiology of cerebrospinal fluid (CSF). We review current evidence and new concepts relating to CSF physiology with respect to CSF secretion, circulation and resorption and we highlight key pathophysiological associations including the relationship between CSF and intracranial pressure. Recent findings CSF secretion occurs primarily via the choroid plexus. Various transport mechanisms facilitate CSF secretion...
Photodynamic therapy combined with surgery for hidradenitis suppurativa: A case reportPublication date: December 2019Source: Photodiagnosis and Photodynamic Therapy, Volume 28Author(s): Dan Luo, Yang Tan, Qionghui Cheng, Jinjin Wu, Xia LeiAbstractHidradenitis Suppurativa (HS) is a distressing painful chronic inflammatory skin follicular condition. It is a challenge to achieve better therapeutic effect and lower recurrence rate. In this report, ALA-PDT combined with surgery for the treatment achieved...
In-vivo techniques for determining nephron numberPurpose of review Many studies have suggested low nephron endowment at birth contributes to the risk of developing hypertension and chronic kidney disease (CKD) later in life. Loss of nephrons with age and disease is largely a subclinical process. New technologies are needed to count nephrons as glomerular filtration rate (GFR) is a poor surrogate for nephron number. Recent findings Cortical volume, glomerular density, and percent globally sclerotic...
A Distorted Body Schema and Susceptibility to Experience Anomalous Somatosensory Sensations in Fibromyalgia SyndromeObjectives: Evidence suggests there to be an association between chronic pain and disruption of the body schema. We tested the hypothesis in fibromyalgia syndrome. Methods: We investigated distinct perceptual aspects of the body schema both in a sample of patients with FMS and in healthy controls. Performances on the left/right judgment task were measured; tactile acuity was assessed...
Patient characteristics when starting treatment and patterns of treatment in adults with chronic immune thrombocytopeniaAsymptomatic patients with primary chronic immune thrombocytopenia (ITP) are not recommended treatment if their platelet counts are above 30 × 109/l. Factors such as age and comorbidities may influence clinical manifestations and should be considered for treatment decisions. The aim of this study was to determine the impact of clinical characteristics for initiation of ITP treatment,...
Methyl Paraben May Increase the Risk of Pruritus in African Americans Whereas Triclosan Is Inversely Associated With Pruritus and EczemaBackground Phenols and parabens (P&Ps) are commonly found in skin care products. However, P&Ps' role in pruritus and eczema has not been studied. Objective The aim of the study was to investigate the association between P&Ps, and pruritus and eczema. Methods This is a cross-sectional population-based study of 2202 participants. We examined the association...
Skeletal Changes Associated with OsteoarthritisAbstractOsteoarthritis (OA) is a degenerative joint disorder in which progressive articular cartilage loss occurs alongside pathological changes in subchondral bone and other joint tissues. The pathophysiological role of bone in OA has been a point of interest for many years and has resurfaced again in recent years as a potential target for new treatments. Articular cartilage and subchondral bone together form the osteochondral unit. Its homeostasis...
Philosophical Transactions of the Royal Society ATheme issue 'Environmental loading of heritage structures' compiled and edited by Alison Raby, Alessandro Antonini, Dina D'Ayala and James BrownjohnVol. 377, No. 2155, (September 2019) The above issue is now available online at:https://royalsocietypublishing.org/toc/rsta/2019/377/2155?ai=aqlb&ui=cbwb&af=HClick the links below to view the abstract for each article, or click the link above to view all Just Released articles for this journal.INTRODUCTIONIntroduction:...
Journal of the European Academy of Dermatology and Venereology,Early ViewOnline Version of Record before inclusion in an issueLetters to the EditorSeasonality of acne severity in Korean patients: data from a dermatologic clinic and military hospitalK.Y. Park, G.J. Jeong, S.J. Seo, M.N. Kim, N.‐K. RhoVersion of Record online: 14 August 2019Original ArticlesUngual warts: comparison of treatment with intralesional bleomycin and electroporation in terms of efficacy and safetyN.G. Di Chiacchio, N. Di...
Journal of Surgical OncologyVolume 120, Issue 4Pages: 567-812September 15, 2019ISSUE INFORMATIONIssue Information ‐ Ed BoardPages: 567 | First Published: 19 August 2019Issue Information ‐ TOCPages: 568-572 | First Published: 19 August 2019REVIEW ARTICLEBreast implant–associated anaplastic large cell lymphoma, a systematic review and in‐depth evaluation of the current understandingPeggy J. Ebner BA, Alice Liu BA, Daniel J. Gould MD, PhD, Ketan M. Patel MDPages: 573-577 | First Published: 01 August...
Takotsubo syndrome: a neurocardiac syndrome inside the autonomic nervous systemLevels of angiotensin peptides in healthy and cardiovascular/renal-diseased paediatric population—an investigative reviewAbstractThe renin-angiotensin-aldosterone system (RAAS) plays a major role in the regulation of blood pressure and homeostasis. Therefore, it is a commonly used target for pharmacotherapy of cardiovascular diseases in adults. However, the efficacy of this pharmacotherapy can only be limitedly derived...
Contextualism in Normative Political Theory and the Problem of Critical DistanceAbstractPolitical theory is contextualist when factual claims about context are part of the justification of normative political judgments. There are different kinds of contextualism depending on whether context is relevant for the formulation and justification of political principles (methodological contextualism), whether principles themselves are contextually specific (theoretical contextualism), or whether context...
Characterization of the microbiota in long- and short-term natural indigo fermentationAbstractThe duration for which the indigo-reducing state maintenance in indigo natural fermentation in batch dependent. The microbiota was analyzed in two batches of sukumo fermentation fluids that lasted for different durations (Batch 1: less than 2 months; Batch 2: nearly 1 year) to understand the mechanisms underlying the sustainability and deterioration of this natural fermentation process. The transformation...
Mimicking nature-made beta cells: recent advances towards stem cell-derived isletsPurpose of review Stem cell-derived islets are likely to be useful as a future treatment for diabetes. However, the field has been limited in the ability to generate β-like cells with both phenotypic maturation and functional glucose-stimulated insulin secretion that is similar to primary human islets. The field must also establish a reliable method of delivering the cells to patients while promoting rapid in-vivo engraftment...
Cardiovascular consequences of obstructive sleep apnea in different study models and novel perspectivesPurpose of review Obstructive sleep apnea (OSA) is heterogeneous in terms of contributing pathophysiological mechanisms, clinical presentation, and consequences. Different study models from animal models of intermittent hypoxia over case-control, cohort, and population-based observational studies to uncontrolled interventional and randomized controlled interventional trials have contributed to the...
JAMA CLINICAL REVIEWS Reducing the Intensity of Antiplatelet Therapy Following Coronary Stent ProceduresA conversation with Greg Curfman, MD, JAMA Deputy Editor and a cardiologist, who reviews 2 new studies showing that a short duration of dual antiplatelet therapy may not result in more myocardial ischemic events.11 min 31 sec / 0.5 CME Listen Now ►Subclinical HypothyroidismSubclinical hypothyroidism is common, but it is not clear how best to treat it. Anne R. Cappola, MD, ScM, professor of medicine...
Locations for Adductor Canal Block: Proximal adductor canal injections were associated with lower...
Locations for Adductor Canal Block: Proximal adductor canal injections were associated with lower first 24-h morphine consumption than when injections were more distal. Decreases in quadriceps strength were similar whether the injection was made in a proximal, mid-, or distal adductor canal location.Pectoralis-II Myofascial Block and Analgesia: This meta-analysis includes 14 randomized trials comparing pectoralis-II block with paravertebral blocks and found that there were no differences in pain...
Perioperative Medicine Early Postnatal Exposure to Isoflurane Disrupts Oligodendrocyte Development and Myelin Formation in the Mouse HippocampusQun Li, Ph.D.; Reilley P. Mathena, B.S.; Jing Xu, M.D.; O'Rukevwe N. Eregha, B.A.; Jieqiong Wen, B.S.; Cyrus D. Mintz, M.D., Ph.D.Anesthesiology Published online August 19, 2019. doi:10.1097/ALN.0000000000002904CorrespondenceNeurologic Examination for Anesthesiologists: CommentGordon B. Drummond, M.D., F.R.C.A., F.R.C.P.Ed.Anesthesiology Published online...
Journal of Cosmetic DermatologyEarly ViewOnline Version of Record before inclusion in an issueCOSMETIC COMMENTARYEvolving beauty—Creating and transforming inequalitiesSusruthi Rajanala BA, Mayra B. C. Maymone MD, DSc, Neelam A. Vashi MDVersion of Record online: 17 August 2019ORIGINAL CONTRIBUTIONSEvaluation of serum interleukin 17 and zinc levels in recalcitrant viral wartAfaf Helmy Ghanem MD, Abdulla Mohamed Esawy MD, Naglaa Ali Khalifa MD, Hend Mahmoud Kamal MScVersion of Record online: 14 August...
Patient-Reported Outcome Measures in Atopic Dermatitis and Chronic Hand Eczema in AdultsAbstractPatient-reported outcome measures (PROMs) provide an important complement to physician-assessed clinical outcome measures in dermatologic diseases such as atopic dermatitis (AD) and chronic hand eczema (CHE). AD and CHE are chronic and relapsing inflammatory skin conditions that often co-occur. While both diseases result in various signs and symptoms that are burdensome and can negatively affect patients'...
Man is the measure of all thingsAbstractOur system of measures referred to human proportions and human perception, as Protagoras stated, is "Man is the measure of all things". In this paper, we present an overview of the measure of Man as a travel on time from the point of view of the past historical development to the future with the insight of different disciplines such as Anthropology, Ergonomics, and Human Factors. The key concept is that all the most famous scholars, architects artists and philosophers...
Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvementThe correct name of the 9th Author is David J. Margolis. The original article was corrected.Letter to the Editor: Clinically relevant drug–drug interactions among elderly people with dementiaLetter to editor: Clinically relevant drug–drug interactions among elderly people with dementiaInteraction between paracetamol and lamotrigine: new insights from the FDA...
Sheilagh Ogilvie: The European guilds: an economic analysisGovernance and the political entrepreneurBusy doing nothing: why politicians implement inefficient policiesAbstractA substantial body of literature suggests that politicians are blocked from implementing efficient reforms that solve substantial problems because of special interest groups or budget constraints. Despite the existing mechanisms that block potentially efficient reforms, real-world data show that a large number of new programs...
Editorial: Special Issue on Mental Health Issues in Autism Spectrum DisorderAutism Spectrum Disorder and Specific Phobia: the Role of Sensory Sensitivity: Brief ReviewAbstractAutism spectrum disorder (ASD) is a common neurodevelopmental disorder affecting approximately 1 in 59 children (Baio et al. MMWR Surveillance Summaries, 67(6), 1, 2018). A commonly experienced psychiatric comorbidity in ASD is anxiety. Although this is known, little research has been done on the specific issues concerning specific...
At the zero degree / Below the minimum: Wage as sign in Israel's split labor marketAbstractMarx conceived of the reproduction of labor-power as a circuit in which the wage must suffice to purchase the commodities necessary to meet the worker's "so-called necessary requirements," which are "products of history." In this article, I argue that, through ethnographic investigation of the wage as a sign of these requirements, we can arrive at a wealth of knowledge about how the wage helps to construct...
Retinal detachment and uveitis at a tertiary center over 10 years: the King Khaled Eye Specialist Hospital (KKESH) Uveitis Survey Study GroupAbstractPurposeTo evaluate the frequency, etiology, treatment, and visual prognosis of retinal detachment (RD) in patients with uveitis.MethodsA retrospective review was performed in 707 consecutive patients (1042 eyes) with uveitis, of whom 97 (13.7%) (157 eyes [15.1%]) had RD.ResultsThere were 126 (12.1%) eyes with exudative retinal detachment (ERD), 16 (1.5%)...
Play in the Information AgeAbstractThis article is an inquiry on the role of play in shaping the cultures of the Information Age. By applying concepts from Postphenomenology and the Philosophy of Information, this paper argues that play and computation share a capacity to shape human experience. I will apply the concept of re-ontologization to describe the effect that computation has had in shaping the world. I will apply the concept of relational strategies to argue that play is a way of interfacing...
Five tips for back-to-school vaccinations,The arrival of August brings the beginning of a new school year for students from kindergarten through high school. As a part of the back-to-school progress, most school districts require a series of vaccinations before returning to the classroom. Keeping children up-to-date on vaccinations protects them from vaccine-preventable infections that can be spread throughout schools and day care centers.
The top articles in RadiologyLatest ArticlesOriginal ResearchBreast Imaging Benign Breast Papilloma without Atypia: Outcomes of Surgical Excision versus US-guided Directional Vacuum-assisted Removal or US Follow-up US-guided directional vacuum-assisted removal or US follow-up without intervention could be an alternative to surgical excision for benign breast papilloma without atypia. Hye Young Choi, Sun Mi Kim...Woo Kyung Moon Cardiac Imaging Acute Effects of Electronic Cigarette Aerosol Inhalation...
Correction to: Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4In the published article, the Fig. 2 was published incorrectly. The correct Fig. 2 is given below.Correction to: Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesionIn the published article, the legend for figure 3 was incorrect. The correct legend is given below.The expression of circulating miR-504 in plasma is associated with EGFR mutation status...
Incidental finding of a mass fitting into a patent foramen ovaleHemodynamic vise in obstructed total anomalous pulmonary venous connectionAn unusual case of double-chambered left ventriclePrognostic value of exercise stress echocardiography in patients with secondary mitral regurgitation: a long-term follow-up studyAbstractBackgroundSecondary mitral regurgitation (MR) remains a challenging problem in the diagnosis and treatment of patients with heart failure. Although it is well known that secondary...
Sprachenlernen hält Senioren geistig fitDas Erlernen einer Fremdsprache ist für das Gehirn ein optimales Trainingsprogramm und verbessert die kognitive Plastizität, egal wie alt der Sprachschüler bereits ist.Gesucht: Junge Ärzte für alte PatientenSGLT-2-Hemmer hilft Diabetikern mit HerzinsuffizienzEtwa ein Drittel aller Patienten mit Herzinsuffizienz leidet an einem Diabetes. Diese Patienten können besonders von der Therapie mit einem SGLT2-Inhibitor profitieren.Wird alten Patienten zu rasch ein...
Correction to: Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanomaThe original version of this article unfortunately contained an error in author group. The first author name was repeated twice.Chemical constituents of the Vietnamese plants Dalbergia tonkinensis Prain and Cratoxylum formosum (Jack) Dyer in Hook and their DPPH radical scavenging activitiesAbstractPhytochemical...
Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH)Publication date: 1 December 2019Source: Molecular and Cellular Endocrinology, Volume 498Author(s): Lu Han, Stefanie Bittner, Dachuan Dong, Yuan Cortez, Hunter Dulay, Sara Arshad, Wen-Jun Shen, Fredric B. Kraemer, Salman AzharAbstractCreosote bush (Larrea tridentata)-derived nordihydroguaiaretic acid (NDGA) was shown to have profound effects on the core components...
Introducing the JAAOS Blog: Sounds From The Training RoomNo abstract availableAnkle Injuries in DancersThe term dance encompasses a broad range of different styles; much of the orthopaedic literature has focused on ballet dancers. Injury is common in dancers at all levels, and many serious dancers sustain multiple injuries as they progress through their career. Foot and ankle injuries are among the most common injuries experienced by dancers. These injuries include those that are specific to dancers...
PD-L1 Detection—Pearls and Pitfalls Associated With Current Methodologies Focusing on Entities Relevant to DermatopathologyAbstract: PD-L1 is a transmembrane glycoprotein with an extracellular as well as an intracellular cytoplasmic domain. Physiologically, it plays a pivotal role in regulating T-cell activation and tolerance. Many tumor cells have exploited this regulatory mechanism by overexpressing PD-L1 in an effort to escape immunologic surveillance. In this review, we parse the literature regarding...
Recent Developments in the Treatment of Mantle Cell LymphomaNo abstract availableExploration of Pregnancy-Related Changes in Breast TissueNo abstract availableA New Approach to Spur the Immune System to Attack LymphomaNo abstract availableImproving Cancer Outcomes Through Weight LossNo abstract availableIdentifying Mechanisms of Resistance to ABT-199 in LymphomasNo abstract availableUnconscious Bias Study Reveals Disparities in Conference IntroductionsNo abstract availableThe States' Role in Health...
Guest Editorial: Innovations in Foot and Ankle Sports Injury TreatmentNo abstract availableNew Option for Achilles Tendon Ruptures, Combining the Best of All: The PARS-DresdenSurgical treatment remains the standard of care for active patients with acute midsubstance Achilles tendon ruptures. Minimal invasive surgery, rupture's site hematoma preservation, strong fixation, avoidance of sural nerve entrapment, and early rehabilitation are essential concepts desirable for any Achilles tendon repair....
Suicide Attempt Resiliency in American Indian, Hispanic, and Anglo Youth in New Mexico: The Influence of Positive Adult RelationshipsThe purpose of this study was to identify whether positive relationships with adults at home, school, and in the community are protective for suicide among American Indian/Alaska Native, Hispanic, and Anglo adolescents. Using data from the New Mexico version of the 2015 Centers for Disease Control and Prevention Youth Risk Behavior Survey, we found that positive relationships...
Journal of Surgical Oncology Early ViewOnline Version of Record before inclusion in an issueRESEARCH ARTICLESDiscordance in prediction of prognosis among patients with intrahepatic cholangiocarcinoma: A preoperative vs postoperative perspectiveAmika Moro MD, Anghela Z. Paredes MD, Ayesha Farooq MBBS, Kota Sahara MD, Diamantis I. Tsilimigras MD, Rittal Mehta MPH, BDS, Itaru Endo MD, PhD, Alfredo Guglielmi MD, Luca Aldrighetti MD, Sorin Alexandrescu MD, Hugo P. Marques MD, Feng Shen MD, Bas G. Koerkamp...
EMS AIRWAY,When CPAP Is Not WorkingBy Joseph P. Hopple, NRPRecognizing deteriorating patients and changing our therapy can give these very sick patients the best opportunity for a positive outcome.Understanding Aphasia: Realities and Strategies for EMS ProvidersBy Ellayne S. Ganzfried, M.S., CCC-SLP , Avi GoldenAvi Golden is an EMT who can no longer talk after suffering a stroke. He now makes it his mission to educate others about those dealing with aphasia.
The LaryngoscopeEarly ViewOnline Version of Record before inclusion in an issueHead and NeckTriological Society Best PracticeShould an elective neck dissection be performed for maxillary sinus squamous cell carcinoma?Michael H. Berger MD, Bobby A. Tajudeen MD, Maie A. St. John MD, PhD, Tjoson Tjoa MD, Edward C. Kuan MD, MBAVersion of Record online: 16 August 2019Allergy/RhinologyOriginal ReportsAnemia and blood transfusion requirements in endoscopic sinus surgery: A propensity‐matched analysisRoman...
Audio Summary: Effect of Maintenance Olanzapine vs Placebo on Psychotic Depression Relapse, Abnormal TFTs and Preterm Birth, USPSTF BRCATesting Guidelines, and moreORIGINAL INVESTIGATIONEffect of Continuing Olanzapine vs Placebo on Relapse Among Patients With Psychotic Depression in Remission: The STOP-PD II Randomized Clinical TrialAlastair J. Flint, MB; Barnett S. Meyers, MD; Anthony J. Rothschild, MD; et al.Earn CME creditEditorial: Maintenance Treatment for Psychotic Depressive Disorders: Progress...
Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract InfectionsSanyukta Desai, Paul L. Aronson, Veronika Shabanova, Mark I. Neuman, Frances Balamuth, Christopher M. Pruitt, Adrienne G. DePorre, Lise E. Nigrovic, Sahar N. Rooholamini, Marie E. Wang, Richard D. Marble, Derek J. Williams, Laura Sartori, Rianna C. Leazer, Christine Mitchell, Samir S. Shah and ON BEHALF OF THE FEBRILE YOUNG INFANT RESEARCH COLLABORATIVECommentaryAn End in Sight: Shorter Duration of Parenteral...
Educational inequalities in the impact of chronic diseases on exit from paid employment among older workers: a 7-year prospective study in the NetherlandsKaren Oude Hengel, Suzan J W Robroek, Iris Eekhout et al. (2019-08-13)10.1136/oemed-2019-105788
Variables associated with 30‐day postoperative complications in lower extremity free flap reconstruction identified in the ACS‐NSQIP databaseJacob Veith MD, Daniel Donato MD, Kathleen Holoyda MD, Andrew Simpson MD, Jayant Agarwal MDVersion of Record online: 16 August 2019
MycosesAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.Original ArticlesCharacterization of Candidemia in Patients with Recent Surgery: A 7‐Year ExperienceElena Orsetti, Lucia Brescini, Sara Mazzanti, Francesca Trave, Gianluca Morroni, Anna Maria Masucci, Francesco BarchiesiFirst Published: 17 August 2019Original ArticlesEfficiency of A. fumigatus‐specific IgG and galactomannan testing in the diagnosis...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,