SCCMPediatric Critical Care MedicineCritical Care Explorations,https://journals.lww.com/ccmjournal/toc/publishahead,Online First - Last Updated: July 15, 2019The editors of this journal are pleased to offer electronic publication of accepted papers prior to print publication. These papers can be cited using the date of access and the unique DOI number. Any final changes in manuscripts will be made at the time of print publication and will be reflected in the final electronic version of the issue.Disclaimer:...
Patient Outcomes and Cost-Effectiveness of a Sepsis Care Quality Improvement Program in a Health SystemObjectives: Assess patient outcomes in patients with suspected infection and the cost-effectiveness of implementing a quality improvement program. Design, Setting, and Participants: We conducted an observational single-center study of 13,877 adults with suspected infection between March 1, 2014, and July 31, 2017. The 18-month period before and after the effective date for mandated reporting of...
SCCM Pediatric Critical Care MedicineCritical Care Explorations,https://journals.lww.com/ccmjournal/toc/publishaheadOnline First - Last Updated: July 15, 2019The editors of this journal are pleased to offer electronic publication of accepted papers prior to print publication. These papers can be cited using the date of access and the unique DOI number. Any final changes in manuscripts will be made at the time of print publication and will be reflected in the final electronic version of the issue.Disclaimer:...
Cellular aging over 13 years associated with incident antinuclear antibody positivity in the Baltimore Longitudinal Study of AgingPublication date: Available online 11 July 2019Source: Journal of AutoimmunityAuthor(s): Helen C.S. Meier, Christine G. Parks, Hans B. Liu, Dale P. Sandler, Eleanor M. Simonsick, Kevin Deane, Nan-ping WengAbstractAge-associated increases in antinuclear antibodies (ANA) in the general population are commonly noted but the mechanisms underlying this observation are unclear....
Table of ContentsCancer Research July 2019; 79 (14) Breaking InsightsHighlights from Recent Cancer LiteratureReviewExosomal Induction of Tumor InnervationPaola D. VermeerCancer Research HighlightsNew Functions of Long Noncoding RNAs during EMT and Tumor ProgressionChunlai LiThe Gut Microbiome: A New Player in Breast Cancer MetastasisWendy V. IngmanGenome and EpigenomeAuthorChoice SATB2-AS1 Suppresses Colorectal Carcinoma Aggressiveness by Inhibiting SATB2-Dependent Snail Transcription and Epithelial–Mesenchymal...
New clinical trial rules: Academic trials and tribulationsArun BhattPerspectives in Clinical Research 2019 10(3):103-105Does India need more medical scientists?Suhasini SharmaPerspectives in Clinical Research 2019 10(3):106-107Indian Council of Medical Research's National Ethical Guidelines for biomedical and health research involving human participants: The way forward from 2006 to 2017Sapan Kumar Behera, Saibal Das, Alphienes Stanley Xavier, Sandhiya Selvarajan, Nishanthi AnandabaskarPerspectives...
Cancer Research and Clinic. Year 2019 Issue 05 is now available on CAOD.In this issue:Expression of programmed death ligand 1 in lung adenocarcinoma and its significance (程序性死亡受体配体1在肺腺癌中的表达及意义)Meng Yi, ,Wu Hongyan, ,Fan Xiangshan, ,Wang Lifeng...... page:289-293Expression of thyroid transcription factor 1 in patients with lung adenocarcinoma and its correlation with the prognosis of patients with advanced lung adenocarcinoma (甲状腺转录因子1在肺腺癌患者中的表达及其与晚期肺腺癌预后的相关性)Lian Juanwen, ,Sun Haifeng, ,Fan Yu, ,Xu...
Working across borders for good health and evidence-based health care for all. Aligning with Sustainable Development Goal #3 (Good Health and Well-Being), Springer has curated content around global child health. Selected chapters, articles & special issues are FREE to access through August 15, 2019. Open Access articles are always free to read.Articles covering child health concerns from across the globeTarget © © alphaspirit / stock.adobe.comRead and download leading content from across...
What Makes the "Perfect" Inpatient Consultation? A Qualitative Analysis of Resident and Fellow PerspectivesPurpose: To characterize the methods of inpatient consult communication, given new communication modalities; to explore residents' and fellows' perspectives on the ideal consult and how this affects their teaching, learning, and patient safety; and to identify barriers to and strategies for optimizing consultations. Method: Using qualitative grounded theory, the authors conducted semistructured...
Role of the Neonatal Nurse Practitioner in the Community HospitalBackground: The role of the neonatal nurse practitioner (NNP) is well established in the neonatal intensive care unit. The level IV NNP is traditionally supported by large multidisciplinary teams while the level I to III NNP may be the sole in-house provider with limited resources. Purpose: The purpose of this research project is to identify the NNP role, responsibilities, and barriers to practice in the level I, II, and III newborn...
Clinical OtolaryngologyEarly ViewOnline Version of Record before inclusion in an issueEffects of a wireless frequency modulation system on learning ability and emotional and behaviour problem improvement in 11 children with cochlear implantYoung Sang Cho, Ji Hyeon Ahn, Hye Yoon Seol, Sung Hwa Hong, Il Joon MoonVersion of Record online: 11 July 2019Responsiveness of acoustic rhinometry to septorhinoplasty by comparison with rhinomanometry and subjective instrumentsEdward Ansari, Florence Rogister, Philippe...
Long-term safety and vaccine-induced seropositivity in healthy volunteers from HIV vaccine trials: a French cohort studyBackground: The ANRS COV1-COHVAC cohort was a long-term safety cohort of healthy volunteers who received preventive HIV-vaccine candidates in 17 phase I/II clinical trials. Methods: Data collected from the first vaccine candidate administration and annually after inclusion in the cohort included grade 3/4 adverse events and all grade adverse events suggestive of neurological, ophthalmological...
Journal of Cutaneous Pathology Accepted Articles Accepted, unedited articles published online and...
Journal of Cutaneous PathologyAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.Reflectance confocal microscopy may enhance the accuracy of histopathologic diagnosis: a case seriesNeda Shahriari MD, Jane M. Grant‐Kels MD, Harold Rabinovitz MD, NP Margaret Oliviero, Alon Scope MDFirst Published: 12 July 2019Melanocytic dendrites: a pitfall in the evaluation of the Treponema pallidum immunohistochemical...
Neoadjuvante Therapie und Chirurgie beim Melanom: Änderungen in der klinischen Praxis? - Prof. Carola Berking (München) im Interview vom Post ASCO Melanom 2019Ein Highlight des ASCO-Kongresses war die neoadjuvante Therapie des Melanoms mit Ipilimumab und Nivolumab, die sehr hohe pathologische Ansprechraten erreicht, so Prof. Carola Berking. Was das für die Klinik bedeutet und was sich bei den chirurgischen Eingriffen und der Therapie von Rezidiven ändert, erläutert die Expertin im Interview.>>...
Dermatologic TherapyEarly ViewOnline Version of Record before inclusion in an issueIntralesional vitamin D3 versus Candida antigen immunotherapy in the treatment of multiple recalcitrant plantar warts: A comparative case–control studyGhada Fathy, Manal A. Sharara, Ayman H. Khafagye12997 | Version of Record online: 11 July 2019Hidradenitis suppurativa: Clinical characteristics and determinants of treatment efficacySecil Vural, Mustafa Gündoğdu, Bengu N. Akay, Ayşe Boyvat, Cengizhan Erdem, Pelin Koçyiğit, Seher...
Update der Onkopedia-Leitlinie für die chronische lymphatische Leukämie (CLL) Websiteswww.haematologie-fokus.de | www.abbvie-care.de/cll Chemotherapiefreie, zeitlich begrenzte Venetoclax-Kombinationstherapie in der Zweitlinie empfohlen Im Zuge des aktuellen Leitlinien-Updates zur chronischen lymphatischen Leukämie (CLL) hat die Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie (DGHO) die Kombinationstherapie aus Venetoclax (Venclyxto®) und Rituximab durchgängig für die Zweitlinientherapie...
Chondrosarcoma of the jaw: a retrospective series, Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Akram Abdo Almansoori, Hui-Young Kim, Bongju Kim, Soung-Min Kim, Jong-Ho LeeObjectivesLow-grade chondrosarcoma presents with features similar to those of benign lesions, such as chondroma and synovial chondromatosis, increasing the difficulty in reaching an accurate diagnosis preoperatively. In this study, we...
Desmoplastic fibroma associated with tuberous sclerosis: case report and literature review, Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Mina D. Fahmy, Anish Gupta, Ricardo J. Padilla, Annette Segura, Carolyn Dicus BrookesTuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that affects the skin, brain, kidneys, and other organ systems. It may exhibit a wide spectrum of clinical manifestations....
KLF4 expression in the surgical cut margin is associated with disease relapse of oral squamous cell carcinoma,Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Souvick Roy, Madhabananda Kar, Shomereeta Roy, Swatishree Padhi, Arka Saha, Birendranath BanerjeeObjectiveThe presence of cancer stem-like cells (CSCs) in the majority of tumors is one of the factors responsible for disease relapse in oral squamous cell carcinoma...
Upregulation of eukaryotic translation initiation factor 3 subunit a promotes cell survival in ameloblastoma,Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Zhenjiang Ding, Jie Liu, Junting Wang, Biying Huang, Ming ZhongObjectivesThis study aimed to detect the expression of eukaryotic translation initiation factor 3 subunit a (eIF3a) in ameloblastoma (AB) tissues compared with normal oral mucosa (NOM) tissues and investigate...
Chronic treatment with zoledronic acid alters the expression levels of inflammatory, bone, and apoptotic markers and Toll-like receptors 2 and 4 in rat dental pulp,Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Paulo Goberlânio de Barros Silva, Antonio Ernando Carlos Ferreira, Camila Carvalho de Oliveira, Maria Elisa Quesado Lima Verde, Milena Oliveira Freitas, Fabrício Bitu Sousa, Mário Rogério Lima Mota, Ana Paula...
Therapeutic efficacy of propranolol for infantile hemangiomas, Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Wenli Wu, Hongtao Wang, Jiansuo Hao, Zijun Gao, Fan Li, Yiyang ChenObjectives.This was a retrospective study to analyze the clinical therapeutic efficacy of propranolol in patients with infantile hemangioma (IH).Study Design.Patients with IH were treated with propranolol (2–4.5 mg/kg/day). Those patients...
Serum and salivary interleukin-4 levels in patients with oral lichen planus: A systematic review and meta-analysis, Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Hamid Reza Mozaffari, Elisa Zavattaro, Mina Saeedi, Pia Lopez-Jornet, Masoud Sadeghi, Mohsen Safaei, Mohammad Moslem Imani, Reza Nourbakhsh, Hedaiat Moradpoor, Amin Golshah, Roohollah SharifiObjectiveCytokines have an important role in keratinocyte...
Risk factors for caries development in primary Sjogren syndrome,Publication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Nicola Berman, Frederick Vivino, Joshua Baker, Jonathan Dunham, Andres PintoObjectivesThe aim of this study was to compare the risk factors for caries between patients with primary Sjogren syndrome (SS) and those with non-Sjogren syndrome (NSS) salivary hypofunction and to identify the prevalence of incisal...
An, Miranda B. BS; Rotunda, Adam M. MDDermatologic Surgery: July 09, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/DSS.0000000000002026Commentary: PDF OnlyBUYPAPAuthor InformationArticle Metrics© 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Routt, Ethan MD; Ratner, Desiree MDDermatologic Surgery: July 01, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/DSS.0000000000001985Letters and Communications: PDF OnlyBUYPAPAuthor InformationArticle Metrics© 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Baltz, Julia O. MD; Jellinek, Nathaniel J. MDDermatologic Surgery: July 01, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/DSS.0000000000001998Commentary: PDF OnlyBUYPAPAuthor InformationArticle Metrics© 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
Chondrosarcoma of the jaw: a retrospective seriesPublication date: August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 2Author(s): Akram Abdo Almansoori, Hui-Young Kim, Bongju Kim, Soung-Min Kim, Jong-Ho LeeObjectivesLow-grade chondrosarcoma presents with features similar to those of benign lesions, such as chondroma and synovial chondromatosis, increasing the difficulty in reaching an accurate diagnosis preoperatively. In this study, we retrospectively...
Introducing the L-Lift—A Novel Approach to Treat Age-Related Facial Skin Ptosis Using A Collagen StimulatorNo abstract availableCommentary on Intralesional Deoxycholic Acid as a Neoadjuvant Treatment for a Large LipomaNo abstract availableTime to Move on From Prescribing Oral Antibiotics as Prophylaxis for Mohs?No abstract availableOutcomes for Basal Cell Carcinoma Treated With Vismodegib Extended Alternate Day DosingNo abstract availableCommentary on Transungual Excision of Glomus TumorsNo abstract...
Selim Berker's Combinatorial Argument against Practical Reasons for Belief,AbstractIn a recent paper, Selim Berker (Analytic Philosophy, 59, 427-470, 2018) develops an abductive argument against practical reasons for belief that exploits an alleged difference between epistemic and practical reasons. According to Berker, epistemic reasons for belief balance to suspension. If I have equally strong epistemic reasons to believe and disbelieve some proposition, I lack sufficient reason either to believe...
Merkelzellkarzinom, ZusammenfassungDas Merkelzellkarzinom ist ein seltener, hoch aggressiver Hauttumor des älteren Menschen. Er besitzt neuroendokrine Eigenschaften. Die Pathogenese ist mit chronischer UV-Licht-Exposition und dem Merkelzell-Polyomavirus assoziiert. Klinisch fällt das Merkelzellkarzinom durch einen solitären, kutan oder subkutan gelegenen, roten bis bläulichen Knoten auf. Da der Tumor frühzeitig lymphogen metastasiert, sind zum Zeitpunkt der Diagnosestellung in etwa 30 % der Fälle...
Management gutartiger Hirntumoren: Meningeome und Vestibularisschwannome,ZusammenfassungMeningeome und Vestibularisschwannome zählen zu den gutartigen intrakraniellen Tumoren und gehen von den Hirnhäuten bzw. den Hirnnerven aus. Die Inzidenz ist mit 4,1 bzw. 1 Neuerkrankung/100.000 Einwohner sehr niedrig, wobei die Anzahl mittels Magnetresonanztomographie (MRT) steigt. Erstbefunde zufällig entdeckter Tumoren ohne neurologisches Defizit, ohne Symptomatik und ohne wesentliche Raumforderung können zunächst...
Jüngste Entwicklungen in der Kopf-Hals-Immunologie,ZusammenfassungImmunologische Vorgänge spielen eine wesentliche Rolle bei der Pathogenese von Erkrankungen des Kopf-Hals-Bereichs. In diesem Zusammenhang ist nicht nur an Allergien oder an Infektionen im Bereich der Mandeln, der Nasennebenhöhlen und des Ohres zu denken, auch Entstehung, Wachstum und Metastasierung von malignen Tumoren des Kopf-Hals-Bereichs werden maßgeblich vom Immunsystem beeinflusst. Die Rekrutierung von weißen Blutkörperchen...
Diagnostik und Therapie der akuten myeloischen LeukämieZusammenfassungIm April 2018 ist die Neuauflage der Onkopedia-Leitlinie zur akuten myeloischen Leukämie (AML) als Aktualisierung von Vorversionen aus den Jahren 2010 und 2017 erschienen. Zwei wesentliche positive Entwicklungen auf dem Gebiet dieser immer noch schwer zu behandelnden Erkrankung machten die Überarbeitung erforderlich: erstens neue Erkenntnisse zu Risikostratifizierung und Monitoring und zweitens die Entwicklung und Zulassung neuer...
Correction to: In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrP V180I MutationThe original version of this article unfortunately contained a mistake. The email address Dr. Wen-Quan Zou, one of the corresponding authors should be written as "wxz6@case.edu" instead of "wxz@case.edu".Correction to: Role of Chronic Administration of Antidepressant Drugs in the Prenatal Stress-Evoked Inflammatory Response in the Brain...
AF1q Expression Associates with CD44 and STAT3 and Impairs Overall Survival in Adenoid Cystic Carcinoma of the Head and Neck,AbstractSalivary gland malignancies of the head and neck form a heterogeneous group. Adenoid cystic carcinomas are an aggressive entity of salivary gland malignancies characterized by frequent distant metastases and poor response to radio- and chemotherapy. AF1Q is a MLL fusion partner, which can activate Wnt and STAT3 signaling. Recently, overexpression of AF1q has been identified...
Molecular Network-Based Identification of Circular RNA-Associated ceRNA Network in Papillary Thyroid Cancer,AbstractCircular RNAs (circRNAs) have displayed dysregulated expression in several types of cancer. Nevertheless, their function and underlying mechanisms in papillary thyroid cancer (PTC) remains largely unknown. This study aimed to describe the regulatory mechanisms in PTC. The expression profile of circRNA was download from the Gene Expression Omnibus (GEO) database. The mRNA and miRNA data...
Upregulation of RUNX1 Suppresses Proliferation and Migration through Repressing VEGFA Expression in Hepatocellular CarcinomaAbstractHepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and occurs in people with chronic liver diseases. Current treatment methods include surgery, transplant, and chemotherapy. Our study demonstrates runt-related transcription factor 1 (RUNX1) as a novel molecule in the initiation and development of HCC, and the role of its interaction with...
Open doors, open mindPlädoyer für eine offene Versorgungspsychiatrie,https://link.springer.com/article/10.1007/s00115-019-0715-5?wt_mc=alerts.TOCjournals&utm_source=toc&utm_medium=email&utm_campaign=toc_115_90_7AuthorsAuthors and affiliationsKarl H. Beine1Email author1.Universität Witten/Herdecke – Klinik für Psychiatrie, Psychotherapie und PsychosomatikSt. Marien-Hospital HammHammDeutschlandLeitthemaFirst Online: 23 April 2019142DownloadsZusammenfassungGegen ihren natürlichen Willen...
Wodurch wird die geschlossene Tür ersetzt?Konzeptionelle und ethische Überlegungen zu offenen Unterbringungsformen, formellem Zwang und psychologischem Druck,https://link.springer.com/article/10.1007/s00115-019-0717-3?wt_mc=alerts.TOCjournals&utm_source=toc&utm_medium=email&utm_campaign=toc_115_90_7AuthorsAuthors and affiliationsJakov Gather12Email authorMatthé Scholten2Tanja Henking3Jochen Vollmann2Georg Juckel11.Klinik für Psychiatrie, Psychotherapie und Präventivmedizin, LWL-UniversitätsklinikumRuhr-Universität...
Korrektur des Empfehlungsgrades für TDM(Teil-)stationäre Therapie von Voll- und Minderjährigen mit einer hyperkinetischen Störung in der deutschen PsychiatrieZusammenfassungHintergrundDie Datenlage über die (teil-)stationäre Versorgung von Patienten mit einer hyperkinetischen Störung (HKS, ICD: 10 F90.-) ist durch Routinedatenanalysen aus dem ambulanten Behandlungssektor bzw. aus gemischten Stichproben einzelner Krankenkassen geprägt. Diese Studie analysiert erstmalig eine fallbezogene Stichprobe...
Effect of inulin polymerization degree on various properties of synbiotic fermented milk including Lactobacillus acidophilus La-5 and Bifidobacterium animalis Bb-12,Publication date: August 2019Source: Journal of Dairy Science, Volume 102, Issue 8Author(s): Sebnem Ozturkoglu-Budak, H. Ceren Akal, İlkay Buran, Atila YetişemiyenABSTRACTThe effects of inulin degree of polymerization (DP) on the viabilities of Lactobacillus acidophilus La-5 and Bifidobacterium animalis Bb-12 and on some parameters of...
Towards Holistic Supporting of Play-Based Learning Implementation in Kindergartens: A Mixed Method Study, AbstractUsing a holistic support framework, this study investigated teachers' conceptions of effective play-based learning development and how their perceptions of its effectiveness related to whole-child development. Data were collected from a mixed method study. A total of 286 questionnaires from 50 Hong Kong kindergartens were collected and then 29 principals, head teachers and teachers...
Shared Musical Experiences, Brandon Polite
LncRNA TUG1 promotes cisplatin resistance in esophageal squamous cell carcinoma cells by regulating Nrf2, Zhenghua Zhang; Ran Xiong; Caiwei Li; Meiqing Xu; Mingfa Guo, IGFBP7 regulates sepsis-induced epithelial-mesenchymal transition through ERK1/2 signaling, Xiaolin Wang; Yan Li; Zhenzhen Zhao; Yan Meng ; Jinjun Bian ... Immunomodulatory effect of human amniotic epithelial cells on restoration of ovarian function in mice with autoimmune ovarian disease Qiuwan Zhang; Yating Huang; Junyan Sun; Tingting...
Editorials Editorial Kenneth Aldape New developments and new dilemmas in lower-grade gliomas Roberta Rudà Proton beam therapy in pediatric brain tumor patients: improved radiation delivery techniques improve neurocognitive outcomes Rakesh Jalali; Jayant S Goda Diet and risk of glioma: targets for prevention remain elusive Kyle M Walsh; Elizabeth B Claus Highlights from the Literature Highlights from the Literature Roger Abounader; Krishna Bhat ; Riccardo Soffietti; Sourav Ghosh ; Mariano...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,