Simultaneous Visualization of Endogenous Hcy, Cys, GSH and their Transformation through Different Fluorescence Channels

Studying biologically important species simultaneously is crucial to understand cellular functions and the root causes of related diseases. Direct visualization of endogenous biothiols in biological systems is of great value to understand their biological roles. Herein, a novel multi‐signal fluorescent probe was rationally designed and exploited for simultaneous sensing of Hcy, Cys and GSH from different emission channels. This probe was successfully applied to the simultaneous discrimination and visualization of endogenous Hcy, Cys, GSH and their transformation in living cells.

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