HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge

HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge

HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge, Published online: 18 February 2019; doi:10.1038/s41467-019-08739-4

Oral vaccination is a potential option to elicit systemic and mucosal immunity against HIV. Here, Jones et al. show that oral vaccination with a modified needle-free injector induces protective immunity against SHIV in non-human primates and is superior to topical application of vaccines to oral tissues.

from A via a.sfakia on Inoreader https://go.nature.com/2BF7GBB