Engineered transfer RNAs for suppression of premature termination codons

Engineered transfer RNAs for suppression of premature termination codons

Engineered transfer RNAs for suppression of premature termination codons, Published online: 18 February 2019; doi:10.1038/s41467-019-08329-4

Premature termination codon suppression therapy could be used to treat a range of genetic disorders. Here the authors present a high-throughput cell-based assay to identify anticodon engineered tRNAs with high suppression activity.

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