A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia

A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia

A phenotypic <i>Caenorhabditis elegans</i> screen identifies a selective suppressor of antipsychotic-induced hyperphagia, Published online: 10 December 2018; doi:10.1038/s41467-018-07684-y

The molecular pathway(s) driving antipsychotics (AP) induced hyperphagia remains unclear. A novel C. elegans system is used here to screen for FDA approved drugs that selectively suppresses this response, unraveling potential molecular mediators influencing AP induced hyperphagia in mouse models.

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