[Correspondence] Proton-pump inhibitors and glecaprevir plus pibrentasvir in HCV infection – Authors' reply

We appreciate Guo Yu and colleagues highlighting the limitations of post-hoc analyses; however, in our study,1 we concluded that the sustained virological response 12 weeks after completion of treatment (SVR12) of 97% (30/31) of patients receiving proton-pump inhibitors suggested an absence of effect on efficacy, rather than concluding that high doses of proton-pump inhibitors (equivalent to 40 mg per day of omeprazole) have no effect on efficacy. Conclusions cannot be reached given the small sample size of the subpopulation of patients receiving proton-pump inhibitors in only one study.

from ! ORL Sfakianakis via paythelady.61 on Inoreader http://ift.tt/2ztbEho
via IFTTT