Unexpected extracardiac multifocal adult rhabdomyomas with 10 lesions of the head and neck: epidemiology, diagnosis and therapy

Adult rhabdomyomas (ARMs) are rare solitary benign neoplasms of the head and neck, which are even rarer when multifocal. Owing to the low incidence and the scanty cognation of this peculiar entity, several patients were reported to be misdiagnosed or overtreated. Here, a patient of multifocal ARMs with as many as 10 synchronous lesions is presented. In addition, all published cases of this entity were reviewed from Pubmed, Embase and Web of Science database up to March 1, 2017. Overall, 10 of 29 reported cases had more than 2 lesions, with a maximum of 10 synchronous masses in our report.

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