Endoplasmic reticulum–mitochondrial contacts (EMCs) regulate multiple critical cellular activities, dysregulation of which correlates with various human maladies such as neurodegenerative diseases. A new study makes use of the ascorbate peroxidase proximity-labeling proteomics approach to scrutinize the components of EMCs in live cells, leading to the identification of reticulon 1A as a novel promoter of EMCs.
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Παρασκευή 29 Σεπτεμβρίου 2017
Fishing for key players in ER-mitochondrial contacts [Neurobiology]
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,