Nature Reviews Cancer 17, 489 (2017). doi:10.1038/nrc.2017.52 Authors: Thomas W. Glover, Thomas E. Wilson & Martin F. Arlt Ever since initial suggestions that instability at common fragile sites (CFSs) could be responsible for chromosome rearrangements in cancers, CFSs and associated genes have been the subject of numerous studies, leading to questions and controversies about their role and importance in cancer. It is now (Source: Nature Reviews Cancer)
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Fragile sites in cancer: more than meets the eye
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