Design of a HIFU array for the treatment of deep venous thrombosis: a simulation study

Deep venous thrombosis of the iliofemoral veins is a common and morbid disease, with the recommended interventional treatment carrying a high risk of hemorrhaging and complications. High intensity focused ultrasound delivered with a single element transducer has been shown to successfully precipitate thrombolysis non-invasively in vitro and in vivo . However, in all previous studies damage to the veins or surrounding tissue has been observed. Using a simulation model of the human thigh, this study investigated whether a phased array device could overcome the large focal region limitations faced by single transducer treatment devices. Effects of the size, shape and frequency of the array on its focal region were considered. It was found that a ##IMG## [http://ift.tt/2udqDIu] {$\lambda/2$} spaced array of 7680 elements operating at 500 kHz could consistently focus to a region fully contained within th...

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