The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus –derived serine protease–like protein D

Chronic airway inflammatory diseases, such as chronic rhinosinusitis with nasal polyps and asthma, show increased nasal Staphylococcus aureus colonization. Staphylococcus aureus –derived serine protease–like protein (Spl) D and other closely related proteases secreted by S aureus have recently been identified as inducers of allergic asthma in human subjects and mice, but their mechanism of action is largely unknown. (Source: Journal of Allergy and Clinical Immunology)

from ! Medicine by Alexandros G. Sfakianakis via alwin on Inoreader http://ift.tt/2tRcwVP
via IFTTT