Primary form of malignant melanoma in an ovarian mature cystic teratoma: case report and literature review

Abstract

Germ cell tumours are a common form of ovarian neoplasm; the most common of which is mature cystic teratoma. However, transformation into malignant melanoma is rare. Here, we present a case of a primary malignant melanoma in an ovarian mature cystic teratoma with literature review. A 63-year-old woman presented at our hospital with abdominal distension and pain. Physical examination showed a mobile, non-tender, abdominopelvic mass. Radiological examination revealed a cystic mass with mixed echogenicity. Histopathological review disclosed a primary malignant melanoma arising in an ovarian mature cystic teratoma. The patient died 28 months after the initial diagnosis. Although it is rare for ovarian neoplasms to transform into malignant melanoma in a mature cystic teratoma, it can happen and physicians should be aware of this exceptional kind of malignancy.

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