Dendritic cells conditioned by activin A –induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma

Previously, we demonstrated that regulatory T  (Treg) cells induced by the cytokine activin-A suppress TH2-mediated allergic responses and linked airway disease. Still, the effects of activin-A–induced regulatory T (Act-A-iTreg) cells on the regulation of dendritic cell (DC)–driven allergic inflammation remain elusive. (Source: Journal of Allergy and Clinical Immunology)

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