Αρχειοθήκη ιστολογίου

Τρίτη 2 Φεβρουαρίου 2021

Massive gastric bleeding - perforation of pancreatic pseudocyst into the stomach: A case report and review of literature.

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Massive gastric bleeding - perforation of pancreatic pseudocyst into the stomach: A case report and review of literature.

World J Clin Cases. 2021 Jan 16;9(2):389-395

Authors: Jin Z, Xiang YW, Liao QS, Yang XX, Wu HC, Tuo BG, Xie R

Abstract
BACKGROUND: Pancreatic pseudocyst may cause serious gastrointestinal complications including necrosis, infection, and perforation of the gastrointestinal tract wall, but massive gastric bleeding is very rare.
CASE: We report a rare case of a 49-year-old man with life-threatening gastric bleeding from a pseudoaneurysm of the splenic artery perforating the stomach induced by pancreatic pseudocyst. During hospitalization, gastroscopy revealed a bare blood vessel in an ulcer-like depression of the greater gastric curvature, and computed tomography scan confirmed a pancreatic pseudocyst invading part of the spleen and gastric wall of the greater curvature. Arteriography showed that the bare blood vessel originated from a pseudoaneurysm of the splenic artery. The bleeding was controlled by the trans-arterial embolization, the patient's recovery was rapid and uneventful.
CONCLUSION: Massive gastrointestinal bleeding could be a rare complication of pancreatic pseudo aneurysm.

PMID: 33521106 [PubMed]

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Natural history of inferior mesenteric arteriovenous malformation that led to ischemic colitis: A case report.

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Natural history of inferior mesenteric arteriovenous malformation that led to ischemic colitis: A case report.

World J Clin Cases. 2021 Jan 16;9(2):396-402

Authors: Kimura Y, Hara T, Nagao R, Nakanishi T, Kawaguchi J, Tagami A, Ikeda T, Araki H, Tsurumi H

Abstract
BACKGROUND: Ischemic colitis with inferior mesenteric arteriovenous malformation (AVM) is a rare disease. Although a few reports have been published, no report has described the natural history of idiopathic mesenteric AVM.
CASE SUMMARY: A 50-year-old male was admitted to our hospital due to abdominal pain that had persisted for 3 mo and bloody diarrhea. He had no history of trauma or abdominal surgery. He had undergone two colonoscopies 6 mo and 2 years ago, and they showed only a polyp. He was diagnosed with ischemic colitis with inferior mesenteric AVM following contrast-enhanced abdominal computed tomography (CT) and underwent rectal low anterior resection. He has not had a recurrence of symptoms for 3 years. His history showed that he had undergone non-enhanced abdominal CT 2, 5, and 8 years ago when he had attacks of urinary stones. Retrospectively, dilation of blood vessels around the rectosigmoid colon could have been detected 5 years ago, and these findings gradually became more evident.
CONCLUSION: This is the first report of the natural history of inferior mesenteric AVM.

PMID: 33521107 [PubMed]

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Coil embolization of arterioportal fistula complicated by gastrointestinal bleeding after Caesarian section: A case report.

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Coil embolization of arterioportal fistula complicated by gastrointestinal bleeding after Caesarian section: A case report.

World J Clin Cases. 2021 Jan 16;9(2):403-409

Authors: Stepanyan SA, Poghosyan T, Manukyan K, Hakobyan G, Hovhannisyan H, Safaryan H, Baghdasaryan E, Gemilyan M

Abstract
BACKGROUND: Most intrahepatic arterioportal fistulae (IAPF) are acquired. The few cases of congenital fistulae are diagnosed in infants and children.
CASE SUMMARY: We report a 31-year-old female patient presenting with haematemesis and melena three weeks after delivering her second child. The patient had a 20-year history of abdominal distention and nausea. IAPF, along with splenomegaly and ascites, was found by Doppler sonography and confirmed by computed tomography angiography. The patient was treated with endovascular coil embolization, resulting in occlusion of the fistula.
CONCLUSION: This was an unusual case of possible congenital IAPF that manifested during a second pregnancy and was complicated by portal hypertension.

PMID: 33521108 [PubMed]

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Cholecystoduodenal fistula presenting with upper gastrointestinal bleeding: A case report.

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Cholecystoduodenal fistula presenting with upper gastrointestinal bleeding: A case report.

World J Clin Cases. 2021 Jan 16;9(2):410-415

Authors: Park JM, Kang CD, Kim JH, Lee SH, Nam SJ, Park SC, Lee SJ, Lee S

Abstract
BACKGROUND: Cholecystoduodenal fistula is a rare complication of cholelithiasis. Symptoms are usually non-specific and often indistinguishable from those of etiologic diseases, but it rarely presents as severe gastrointestinal bleeding. Bleeding associated with cholecystoduodenal fistula usually requires surgery because significant bleeding from the cystic artery is unlikely to be resolved by conservative management or endoscopic hemostasis.
CASE SUMMARY: We report a case of cholecystoduodenal fistula that presented with hematemesis which was diagnosed by endoscopy and computed tomography. Endoscopic hemostasis could not be achieved, but surgical treatment was successful. Additionally, we have presented a literature review.
CONCLUSION: Cholecystoduodenal fistula should be considered as differential diagnosis when a patient with history of gallstone disease presents with gastrointestinal bleeding.

PMID: 33521109 [PubMed]

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Rare case of fecal impaction caused by a fecalith originating in a large colonic diverticulum: A case report.

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Rare case of fecal impaction caused by a fecalith originating in a large colonic diverticulum: A case report.

World J Clin Cases. 2021 Jan 16;9(2):416-421

Authors: Tanabe H, Tanaka K, Goto M, Sato T, Sato K, Fujiya M, Okumura T

Abstract
BACKGROUND: Fecal impaction is defined as a large mass of compacted feces in the colon and has the potential to induce a serious medical condition in elderly individuals. Fecal impaction is generally preventable, and early recognition of the typical radiological findings is important for making an early diagnosis. The factors that lead to fecal impaction are usually similar to those causing constipation. Few cases with fecal impaction associated with a diverticulum have been reported.
CASE SUMMARY: We present the case of a 62-year-old woman who suffered from abdominal pain and vomiting, had a medical history of repeated acute abdomen and was diagnosed with fecal impaction in the descending colon based on X-ray and computed tomography (CT) imaging. After examination by gastrografin-enhanced colonography following colonoscopy and CT colonography, the fecalith was suspected to have been produced at the site of a large diverticulum in the transverse colon. The fecalith was surgically resected, and a histological diagnosis of pseudodiverticulum was made. There was no recurrence during 33 mo of follow-up.
CONCLUSION: This case highlights the importance of accurate identification and treatment of a fecal impaction. This case indicated that the endoscopic evacuation and subsequent colonography were effective for identifying a diverticulum that might have caused fecal impaction. A fecal impaction was associated with the diverticulum. Consequently, the planned diverticulectomy was performed. Appropriate emergency medical treatment and maintenance treatments should be selected in such cases to prevent recurrence.

PMID: 33521110 [PubMed]

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Intravitreal dexamethasone implant - a new treatment for idiopathic posterior scleritis: A case report.

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Intravitreal dexamethasone implant - a new treatment for idiopathic posterior scleritis: A case report.

World J Clin Cases. 2021 Jan 16;9(2):422-428

Authors: Zhao YJ, Zou YL, Lu Y, Tu MJ, You ZP

Abstract
BACKGROUND: Posterior scleritis is one of the most easily missed and misdiagnosed diseases in ophthalmology. In this case we treated a patient with intravitreal dexamethasone implant that has not been extensively studied before.
CASE SUMMARY: A 40-year-old female patient who had anxiety, palpitation, and insomnia presented with eye pain and decreased vision in the left eye. An eye examination indicated that her visual acuity (VA) was 40/100. Her left eye presented conjunctival edema, mild exophthalmos, clear cornea, KP(-), and clear aqueous humor. In the fundus, there was a cinerous retinal protuberance. Ultrasonography showed "T-sign" and no systemic association was detected in laboratory examination. One month after injection of dexamethasone implant, the patient exhibited VA of 20/20, fundus serous retinal detachment disappeared, and intraocular pressure of both eyes was at the normal level.
CONCLUSION: Intravitreal injection of dexamethasone implant may be a safe and effective treatment for patients with idiopathic posterior scleritis.

PMID: 33521111 [PubMed]

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Inflammatory myofibroblastic tumor successfully treated with metformin: A case report and review of literature.

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Inflammatory myofibroblastic tumor successfully treated with metformin: A case report and review of literature.

World J Clin Cases. 2021 Jan 16;9(2):429-435

Authors: Liang Y, Gao HX, Tian RC, Wang J, Shan YH, Zhang L, Xie CJ, Li JJ, Xu M, Gu S

Abstract
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a distinct tumor with a low incidence rate, which can be diagnosed at any age with a predilection for children and adolescents. Although IMT is visible in any tissues and organs, it is more commonly found in the lungs. The clinical and radiological manifestations of IMT lack specificity, hence resulting in frequent misdiagnosis. Surgical resection is currently the main therapeutic approach for IMT. Only scarce cases of IMT treated with metformin have been reported. Here we report the case of an IMT patient with partial penile resection treated with metformin.
CASE SUMMARY: A 1-year-old boy was born with a shorter penis, and his foreskin could not be completely turned over. When he was 6 month old, a well-circumscribed mass on the glans was found, while it did not attract the attention of his parents. The mass gradually increased in size over time before he was admitted to the hospital, where physical examination was performed. It was revealed that the glans hidden behind the foreskin had a mass with a diameter of about 4 cm surrounding the penis. The mass appeared to be hard with a smooth surface and poor mobility. The two testicles examined at the bottom of the scrotum were revealed to have a normal size. Magnetic resonance imaging showed a tumor with rich blood supply encircling the cavernosum with a size of 3.5 cm × 2.1 cm × 2.0 cm. A thick urinary line was found without urine dripping, urgency, and urodynia. Surgical treatment was performed. During the operation, it was observed that the mass had surrounded and invaded the c avernosum without obvious boundaries, and that the tumor occupied about one-half of the penis cross-section as well as infiltrated more than one-half of the glans. In addition, the tumor had caused urethral invasion and anterior urethrostenosis. With the intention of keeping the glans and cavernosum, the tumor at the anterior urethra was partially removed, leaving about 30% of the tumor mass. Pathology analysis demonstrated that the tumor was rich in spindle cells with infiltration of inflammatory cells. Immuno-histochemistry analysis indicated that the cells were positive for CD4, CD99, Ki67, BCL2, and CD68, and negative for ALK, MyoG, S100, SOX10, PR, and EMA. Hence, the tumor was diagnosed as IMT. Metformin was prescribed for the patient after the operation, following which an oral dose of 7 mg/kg was given three times a day after meals. Three months later, it was observed that the remaining tumor had completely disappeared and that the urination process from the urethra opening had resumed normal. In addition, there were no side effects observed. There was also no tumor recurrence. The growth and development of the boy were unaffected as a result of the treatment.
CONCLUSION: The tumor was observed to have completely disappeared after treatment with metformin. Our finding is of great significance to facilitate future clinical treatment with IMT.

PMID: 33521112 [PubMed]

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Neonatal isovaleric acidemia

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Neonatal isovaleric acidemia in China: A case report and review of literature.

World J Clin Cases. 2021 Jan 16;9(2):436-444

Authors: Wu F, Fan SJ, Zhou XH

Abstract
BACKGROUND: Isovaleric acidemia (IVA) is a rare autosomal recessive inherited organic acidemia caused by a genetic deficiency of isovaleryl-CoA dehydrogenase (IVD). Its morbidity is low, but mortality is high. There is no effective cure for this disease. Early identification of IVA using clinical features can significantly slow disease progression and reduce mortality. Here we report a Chinese neonate with two mutations of IVD and share valuable information on this disease.
CASE SUMMARY: A 12-day-old male neonate with "poor response for 1 d and repeated convulsions accompanied by high muscle tension for 6 h" was hospitalized. The patient was the first child of nonconsanguineous ethnic Chinese parents. He was delivered by cesarean section due to breech position at 39 + 1 wk of gestation with a birth weight of 3.27 kg. Initially, he suffered from dyspnea and rhinobyon, and at 10 d after birth the patient suddenly developed poor feeding, low response, lethargy and seizures. Organic acid analysis of blood and urine by tandem mass spectrometry and gas chromatography mass spectrometry showed extremely high concentrations of isovaleryl glycine. The patient had an acute episode of IVA causing severe metabolic stress and eventually died.
CONCLUSION: A new case of an IVA patient carrying c.1193G>A (p.Arg398Gln) and c.1208A>G (p.Try403Cys) mutations is reported in China.

PMID: 33521113 [PubMed]

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Malignant solitary fibrous tumor of the greater omentum: A case report and review of literature.

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Malignant solitary fibrous tumor of the greater omentum: A case report and review of literature.

World J Clin Cases. 2021 Jan 16;9(2):445-456

Authors: Guo YC, Yao LY, Tian ZS, Shi B, Liu Y, Wang YY

Abstract
BACKGROUND: Malignant solitary fibrous tumors (SFTs) account for 15%-20% of all SFTs, and malignant SFTs arising from the greater omentum are extremely rare. Most malignant SFTs of the greater omentum are diagnosed via pathological examinations after surgery. In this study, we report a case of malignant omental SFT and review the published literature on this rare malignancy.
CASE SUMMARY: A 64-year-old female presented with an abdominal mass, and underwent exploratory surgery, during which a huge tumor originating from the greater omentum and intraperitoneal implants were identified and resected. The results of the pathological examination, immunohistochemistry staining, and gene sequencing led to the diagnosis of malignant SFT of the greater omentum. The patient died one and a half years later due to tumor recurrence and metastasis.
CONCLUSION: This is the first report of the application of gene sequencing in the diagnosis of malignant SFTs of the greater omentum.

PMID: 33521114 [PubMed]

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Paratesticular liposarcoma: Two case reports.

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Paratesticular liposarcoma: Two case reports.

World J Clin Cases. 2021 Jan 16;9(2):457-462

Authors: Zheng QG, Sun ZH, Chen JJ, Li JC, Huang XJ

Abstract
BACKGROUND: Paratesticular liposarcoma accounts for approximately 7% of scrotal tumors. They are rare lesions of the reproductive system with approximately 90% of the lesions originating from the spermatic cord. Surgery, with the goal of complete resection, is the mainstay for treatment of this disease. However, treatment consisting of extended resection to decrease local recurrence remains controversial.
CASE SUMMARY: We report the cases of two patients with paratesticular liposarcomas who were treated with radical testicular tumor resection without adjuvant therapy. Follow-up investigations at 9 mo showed no sign of recurrence.
CONCLUSION: Surgery is the first-line treatment, regardless of whether it is a recurrent or primary tumor. Extended resection carries a higher risk of complications and should not be performed routinely. Preoperative radiotherapy can reduce the local recurrence rate without affecting the overall survival.

PMID: 33521115 [PubMed]

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Sinistral portal hypertension associated with pancreatic pseudocysts - ultrasonography findings: A case report.

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Sinistral portal hypertension associated with pancreatic pseudocysts - ultrasonography findings: A case report.

World J Clin Cases. 2021 Jan 16;9(2):463-468

Authors: Chen BB, Mu PY, Lu JT, Wang G, Zhang R, Huang DD, Shen DH, Jiang TT

Abstract
BACKGROUND: Sinistral portal hypertension associated with pancreatic pseudocysts is rare, often caused by extrinsic compression of splenic vein, the follow-up examinations by ultrasonography for early diagnosis are quietly necessary since haematemesis, a life-threatening condition. Few studies have reported the ultrasonography findings of sinistral portal hypertension.
CASE SUMMARY: A 52-year-old man presented with acute abdominal pain after drinking, steatorrhea, weight loss and accidentally melena in the past 2 mo. He underwent ultrasound-guided fine needle aspiration in other hospital and diagnosed with pancreatic pseudocysts. Ultrasonography imaging, in our department, appeared as cystic heterogeneous hypoechoic area with the size of 4.7 cm × 3.8 cm that located posterior to the body and tail of pancreas, adjacent to splenic vein associated with thrombosis resulted from compression. Spleen incrassated to approximately 7.3 cm, but no dilation of main portal vein was presented. Color Doppler Flow Imaging demonstrated the formation of splenic venous collateral, nevertheless no significantly flow signals was observed in splenic vein. Pulsed Doppler revealed that the peak velocity of splenic venous collateral was 18.4 cm/s with continuous waveform. Laparotomy confirmed sinistral portal hypertension associated with pancreatic pseudocysts, su bsequently distal pancreatectomy combined with splenectomy and partial gastrectomy was performed.
CONCLUSION: It's important clinically to know the ultrasound appearance of sinistral portal hypertension associated with pancreatic pseudocysts for sonographer and physician.

PMID: 33521116 [PubMed]

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