Expert consensus of the Chinese Association for the Study of Pain on ion channel drugs for neuropathic pain

paythelady.612 shared this article with you from Inoreader Expert consensus of the Chinese Association for the Study of Pain on ion channel drugs for neuropathic pain Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2100-2109. doi: 10.12998/wjcc.v9.i9.2100. ABSTRACT Neuropathic pain (NPP) is a kind of pain caused by disease or damage impacting the somatosensory system. Ion channel drugs are the main treatment for NPP; however, their irregular usage leads to unsatisfactory pain relief. To regulate the treatment of NPP with ion channel drugs in clinical practice, the Chinese Association for the Study of Pain organized first-line pain management experts from China to write an expert consensus as the reference for the use of ion channels drugs . Here, we reviewed the mechanism and characteristics of sodium and calcium channel drugs, and developed recommendations for the therapeutic principles and clinical practice for carbamazepine, oxcarbazepine, lidocaine, bulleyaconitine A, pregabalin, and gabapentin. We hope this guideline provides guidance to clinicians and patients on the use of ion channel drugs for the mana gement of NPP. PMID:33850929 | PMC:PMC8017507 | DOI:10.12998/wjcc.v9.i9.2100 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Chinese Association for the Study of Pain: Expert consensus on diagnosis and treatment for lumbar disc herniation

paythelady.612 shared this article with you from Inoreader Chinese Association for the Study of Pain: Expert consensus on diagnosis and treatment for lumbar disc herniation Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2058-2067. doi: 10.12998/wjcc.v9.i9.2058. ABSTRACT Lumbar disc herniation is a common disease in the clinical context and does great harm to either the physical or mental health of patients suffering from this disease. Many guidelines and consensus for the diagnosis and treatment of lumbar disc herniation have been published domestically and internationally. According to the expert consensus, clinicians could adopt tailored and personalized diagnosis and treatment management strategies for lumbar disc herniation patients. PMID:33850925 | PMC:PMC8017495 | DOI:10.12998/wjcc.v9.i9.2058 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expert consensus of the Chinese Association for the Study of Pain on pain treatment with the transdermal patch

paythelady.612 shared this article with you from Inoreader Expert consensus of the Chinese Association for the Study of Pain on pain treatment with the transdermal patch Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2110-2122. doi: 10.12998/wjcc.v9.i9.2110. ABSTRACT Chronic pain lasting more than 3 mo, or even several years can lead to disability. Treating chronic pain safely and effectively is a critical challenge faced by clinicians. Because administration of analgesics through oral, intravenous or intramuscular routes is not satisfactory, research toward percutaneous delivery has gained interest. The transdermal patch is one such percutaneous delivery system that can deliver drugs through the skin and capillaries at a certain rate to achieve a systemic or local therapeutic effect in the affected area. It has many advantages including ease of administration and hepatic first pass metabolism avoidance as well as controlling drug delivery, which reduces the dose frequency and side effects. If not required, then the patch can be removed from the skin immediately. The scopolamine patch was the first transdermal p atch to be approved for the treatment of motion sickness by the Food and Drug Administration in 1979. From then on, the transdermal patch has been widely used to treat many diseases. To date, no guidelines or consensus are available on the use of analgesic drugs through transdermal delivery. The pain branch of the Chinese Medical Association, after meeting and discussing with experts and based on clinical evidence, developed a consensus for promoting and regulating standard use of transdermal patches containing analgesic drugs. PMID:33850930 | PMC:PMC8017498 | DOI:10.12998/wjcc.v9.i9.2110 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expert consensus on the diagnosis and treatment of myofascial pain syndrome

paythelady.612 shared this article with you from Inoreader Expert consensus on the diagnosis and treatment of myofascial pain syndrome Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2077-2089. doi: 10.12998/wjcc.v9.i9.2077. ABSTRACT Myofascial pain syndrome (MPS) is characterized by myofascial trigger points and fascial constrictions. At present, domestic and foreign scholars have not reached a consensus on the etiology and pathogenesis of MPS. Due to the lack of specific laboratory indicators and imaging evidence, there is no unified diagnostic criteria for MPS, making it easy to confuse with other diseases. The Chinese Association for the Study of Pain organized domestic experts to formulate this Chinese Pain Specialist Consensus on the diagnosis and treatment of MPS. This article reviews relevant domestic and foreign literature on the definition, epidemiology, pathogenesis, clinical manifestation, diagnostic criteria and treatments of MPS. The consensus is intended to normalize the diagnosis and treatment of MPS and be used by first-line doctors, including pain physicians to manage patients with MPS. PMID:33850927 | PMC:PMC8017503 | DOI:10.12998/wjcc.v9.i9.2077 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expert consensus of Chinese Association for the Study of Pain on the radiofrequency therapy technology in the Department of Pain

paythelady.612 shared this article with you from Inoreader Expert consensus of Chinese Association for the Study of Pain on the radiofrequency therapy technology in the Department of Pain Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2123-2135. doi: 10.12998/wjcc.v9.i9.2123. ABSTRACT On the basis of continuous improvement in recent years, radiofrequency therapy technology has been widely developed, and has become an effective method for the treatment of various intractable pain. Radiofrequency therapy is a technique that uses special equipment and puncture needles to output ultra-high frequency radio waves and accurately act on local tissues. In order to standardize the application of radiofrequency technology in the treatment of painful diseases, Chinese Association for the Study of Pain (CASP) has developed a consensus proposed by many domestic experts and scholars. PMID:33850931 | PMC:PMC8017496 | DOI:10.12998/wjcc.v9.i9.2123 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expert panel's guideline on cervicogenic headache: The Chinese Association for the Study of Pain recommendation

paythelady.612 shared this article with you from Inoreader Expert panel's guideline on cervicogenic headache: The Chinese Association for the Study of Pain recommendation Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2027-2036. doi: 10.12998/wjcc.v9.i9.2027. ABSTRACT Cervicogenic headache (CEH) has been recognized as a unique category of headache that can be difficult to diagnose and treat. In China, CEH patients are managed by many different specialties, and the treatment plans remain controversial. Therefore, there is a great need for comprehensive evidence-based Chinese experts' recommendations for the management of CEH. The Chinese Association for the Study of Pain asked an expert panel to develop recommendations for a series of questions that are essential for daily clinical management of patients with CEH. A group of multidisciplinary Chinese Association for the Study of Pain experts identified the clinically relevant topics in CEH. A systematic review of the literature was performed, and evidence supporting the benefits and harms for the management of CEH was summarized. Twenty-four recommendations were f inally developed through expert consensus voting for evidence quality and recommendation strength. We hope this guideline provides direction for clinicians and patients making treatment decisions for the management of CEH. PMID:33850922 | PMC:PMC8017501 | DOI:10.12998/wjcc.v9.i9.2027 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Contributions of aversive environmental stress to migraine chronification: Research update of migraine pathophysiology

paythelady.612 shared this article with you from Inoreader Contributions of aversive environmental stress to migraine chronification: Research update of migraine pathophysiology Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2136-2145. doi: 10.12998/wjcc.v9.i9.2136. ABSTRACT Clinical studies have suggested that internal and/or external aversive cues may produce a negative affective-motivational component whereby maladaptive responses (plasticity) of dural afferent neurons are initiated contributing to migraine chronification. However, pathophysiological processes and neural circuitry involved in aversion (unpleasantness)-producing migraine chronification are still evolving. An interdisciplinary team conducted this narrative review aimed at reviewing neuronal plasticity for developing migraine chronicity and its relevant neurocircuits and providing the most cutting-edge information on neuronal mechanisms involved in the processing of affective aspects of pain and the role of unpleasantness evoked by internal and/or external cues in facilitating the chronification process of migraine headache. Thus, information presented in this review promotes the understanding of the pathophysiology of chronic migraine and contribution of unpleasantness (aversion) to migraine chronification. We hope that it will bring clinicians' attention to how the maladaptive neuroplasticity of the emotion brain in the aversive environment produces a significant impact on the chronification of migraine headache, which will in turn lead to new therapeutic strategies for this type of pain. PMID:33850932 | PMC:PMC8017499 | DOI:10.12998/wjcc.v9.i9.2136 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expert consensus of Chinese Association for the Study of Pain on the non-opioid analgesics for chronic musculoskeletal pain

paythelady.612 shared this article with you from Inoreader Expert consensus of Chinese Association for the Study of Pain on the non-opioid analgesics for chronic musculoskeletal pain Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2068-2076. doi: 10.12998/wjcc.v9.i9.2068. ABSTRACT Chronic musculoskeletal pain (CMP) is a common occurrence in clinical practice and there are a variety of options for the treatment of it. However, the pharmacological therapy is still considered to be a primary treatment. The recent years have witnessed the emergence of opioid crisis, yet there are no relevant guidelines on how to treat CMP with non-opioid analgesics properly. The Chinese Medical Association for the Study of Pain convened a panel meeting to develop clinical practice consensus for the treatment of CMP with non-opioid analgesics. The purpose of this consensus is to present the application of nonsteroidal anti-inflammatory drugs, serotonin norepinephrine reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, muscle relaxants, ion channel drugs and topical drugs in CMP. PMID:33850926 | PMC:PMC8017502 | DOI:10.12998/wjcc.v9.i9.2068 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cervical intervertebral disc degeneration and dizziness

paythelady.612 shared this article with you from Inoreader Cervical intervertebral disc degeneration and dizziness Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2146-2152. doi: 10.12998/wjcc.v9.i9.2146. ABSTRACT Clinical studies have found that patients withcervical degenerative disease are usually accompanied by dizziness. Anterior cervical surgery can eliminate not only chronic neck pain, cervical radiculopathy or myelopathy, but also dizziness. Immunohistochemical studies show that a large number of mechanoreceptors, especially Ruffini corpuscles, are present in degenerated cervical discs. The available evidence suggests a key role of Ruffini corpuscles in the pathogenesis of dizziness caused by cervical degenerative disease (i.e. cervical discogenic dizziness). Disc degeneration is characterized by an elevation of inflammatory cytokines, which stimulates the mechanoreceptors in degenerated discs and results in peripheral sensitization. Abnormal cervical proprioceptive inputs from the mechanoreceptors are transmitted to the central nervous system, resulting in sensory mismatches with vestibular and visual information and leads to dizziness. In addition, neck pain caused by cervical disc degeneration can play a key role in cervical discogenic dizziness by increasing the sensitivity of muscle spindles. Like cervical discogenic pain, the diagnosis of cervical discogenic dizziness can be challenging and can be made only after other potential causes of dizziness have been ruled out. Conservative treatment is effective for the majority of patients. Existing basic and clinical studies have shown that cervical intervertebral disc degeneration can lead to dizziness. PMID:33850933 | PMC:PMC8017505 | DOI:10.12998/wjcc.v9.i9.2146 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Chinese Association for the Study of Pain: Experts consensus on ultrasound-guided injections for the treatment of spinal pain in China (2020 edition)

paythelady.612 shared this article with you from Inoreader Chinese Association for the Study of Pain: Experts consensus on ultrasound-guided injections for the treatment of spinal pain in China (2020 edition) Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2047-2057. doi: 10.12998/wjcc.v9.i9.2047. ABSTRACT Spinal pain (SP) is a common condition that has a major negative impact on a patient's quality of life. Recent developments in ultrasound-guided injections for the treatment of SP are increasingly being used in clinical practice. This clinical expert consensus describes the purpose, significance, implementation methods, indications, contraindications, and techniques of ultrasound-guided injections. This consensus offers a practical reference point for physicians to implement successfully ultrasound-guided injections in the treatment of chronic SP. PMID:33850924 | PMC:PMC8017500 | DOI:10.12998/wjcc.v9.i9.2047 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Chinese Association for the Study of Pain: Expert consensus on chronic postsurgical pain

paythelady.612 shared this article with you from Inoreader Chinese Association for the Study of Pain: Expert consensus on chronic postsurgical pain Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Mar 26;9(9):2090-2099. doi: 10.12998/wjcc.v9.i9.2090. ABSTRACT Chronic postsurgical pain is a common surgical complication that severely reduces a patient's quality of life. Many perioperative interventions and management strategies have been developed for reducing and managing chronic postsurgical pain. Under the leadership of the Chinese Association for the Study of Pain, an editorial committee was formed for chronic postsurgical pain diagnosis and treatment by experts in relevant fields. The editorial committee composed the main content and framework of this consensus and established a working group. The working group conducted literature review (1989-2020) using key words such as "surgery", "post-surgical", "post-operative", "pain", "chronic", and "persistent" in different databases including MEDLINE, EMBASE, PubMed, Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews. Only publications in the English language were included. The types of literature included systematic reviews, randomized controlled studies, cohort studies and case reports. This consensus was written based on clinical practice combined with literature evidence. The first draft of the consensus was rigorously reviewed and edited by all the editorial committee experts before being finalized. The level of evidence was assessed by methodological experts based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. The strength of recommendation was evaluated by all editorial committee experts, and the opinions of most experts were adopted as the final decision. The recommendation level "strong" generally refers to recommendations based on high-level evidence and consistency between clinical behavior and expected results. The recommendation level "weak" generally refers to the uncertainty between clinical behavior and expected results based on low-level evidence. PMI D:33850928 | PMC:PMC8017506 | DOI:10.12998/wjcc.v9.i9.2090 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.