Αρχειοθήκη ιστολογίου

Κυριακή 17 Απριλίου 2022

Females Have Worse Overall and Disease-Specific Survival In HPV-Negative Oropharyngeal Squamous Cell Carcinoma

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Although sex (male versus female) has been identified as an independent prognostic factor in human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC), the role of sex in HPV-negative OPSCC is less understood. The purpose of this study was to measure the association between sex and HPV-negative OPSCC disease-specific survival (DSS) and overall survival (OS). (Source: Journal of Oral and Maxillofacial Surgery)
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Is Bone Grafting during Implant Placement a Protective Factor against the Development of Peri-implantitis? A Retrospective Cohort Analysis

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This study aims to identify if the use of bone grafting at time of implant placement is a protective factor against the development of peri-implantitis. A retrospective cohort study was conducted at the Philadelphia Veterans Affairs Medical Center from 2006 to 2013. Physician encounter notes within three months of implant placement were used to gather data about patients ' health status. Operative report notes were used to assess the use of bone grafting at time of implant placement. Implant status was assessed using dental encounter notes and radiographs from follow-up appointments at one, three, five and 10 years. (Source: Journal of Oral and Maxillofacial Surgery)
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Modified Lip Revision Surgery For The Severe Whistle Lip Deformity In Bilateral Cleft Lip

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Whistle deformity is a sequela of primary surgical repair of the bilateral cleft lip that leads to a vertical tissue deficiency and a non-functional orbicularis oris muscle in the medial portion of the upper lip. This sequel is significantly limiting functionally and esthetically. We propose a complete labial revision with a secondary cheiloplasty of Mulliken and a submucosal inferiorly based flap in the central tubercle to increase the volume at this usually deficient area. (Source: Journal of Oral and Maxillofacial Surgery)
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Is inferior alveolar nerve block needed to perform implant surgery in the posterior mandible? A randomized controlled trial.

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This study aimed to compare the efficacy of the 2 techniques using articaine 4% with epinephrine 1:100,000. (Source: Journal of Oral and Maxillofacial Surgery)
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Intraoperative flap warming: The novel use of a sterile cardiac forced warm air blanket for maintaining optimal flap perfusion.

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The two-team approach in major head and neck/reconstructive surgery can occasionally lead to delays between flap harvest and detachment, due to the complexity and length of the ablative procedure. In order to minimize the potential for flap cooling and the adverse impact on microcirculation, active warming can be beneficial.(1) Intraoperative flap warming to either maintain or improve circulation during free flap harvesting has been performed with a variety of passive and active techniques,(2) however limitations such as a lack of consistent temperature regulation, lack of sterility, inability to directly visualise the flap or the need for acquisition of new equipment for a niche area meant that an ideal solution was lacking. (Source: Journal of Oral and Maxillofacial Surgery)
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Cellular fibroadenoma versus phyllodes tumors: A pre‐operative diagnostic approach based on radiological and cytological features

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Abstract

Objective

This study has been designed in an effort to identify the clinico-radiological and cytological features that could effectively help in differentiating cellular fibroadenoma (CFA) and phyllodes tumors (PT), which have several overlapping characteristics.

Method

Histologically proven cases of CFA and PT were reviewed. Cytological features were assessed and categorized. Clinical and radiological details were also evaluated and he the two groups were compared statistically.

Results

A total of 43 FA and 52 PT were specimens were reviewed. Mean age and tumor size for CFA and PT were 26.05 and 36.94 years, and 3.7 and 6.4 cm, respectively. Univariate analysis and regression models revealed that age >30 years, BIRADS grade of 4 or more, marked cellularity of stromal fragments, more than 30% spindle cells in background cell population and presence of traversing blood vessels in stromal fragments increased the odds of a tumor being phyllodes. The binary logistic regression model was able to predict PT accurately in 87.2% cases (p <  .001).

Conclusion

PT and CFA could be differentiated if cytological findings are cautiously correlated clinically and radiologically. Age, BIRADS category along with assessment of stromal fragments and background population can effectively distinguish between CFA and PT.

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Training the pronunciation of L2 vowels under different conditions: the use of non-lexical materials and masking noise

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Via Phonetica

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Phonetica. 2022 Apr 15. doi: 10.1515/phon-2022-2018. Online ahead of print.ABSTRACTThe current study extends traditional perceptual high-variability phonetic training (HVPT) in a foreign language learning context by implementing a comprehensive training paradigm that combines perception (discrimination and identification) and production (immediate repetition) training tasks and by exploring two potentially enhancing training conditions: the use of non-lexical training stimuli and the presence of masking noise during production training. We assessed training effects on L1-Spanish/Catalan bilingual EFL learners' production of a difficult English vowel contrast (/æ/-/ʌ/). The participants (N = 62) were randomly assigned to either non-lexical (N = 24) or lexical (N = 24) training and were fu...
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Πέμπτη 14 Απριλίου 2022

Superficial parotidectomy with or without great auricular nerve preservation. Is there a difference in postoperative sensory recovery rates and quality of life?

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This study aimed to compare sensory recovery rates and quality of life (QoL) in patients who had undergone superficial parotidectomy and had their GAN preserved or sacrificed. Fifty patients were prospectively analysed, 28 with the GAN preserved, and 22 with it sacrificed. The primary outcomes were tactile sensitivity and QoL. The secondary outcomes were operating times and other complications. (Source: The British Journal of Oral and Maxillofacial Surgery)
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Long-term clinical outcomes of immediate loading versus non-immediate loading in single-implant restorations: a systematic review and meta-analysis

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Dental implant restoration is a predictable treatment option for replacing missing or damaged teeth. Conventional loading requires a prolonged treatment period and second surgical interventions. The aim of this study was to compare the clinical outcomes between immediate and non-immediate (early or conventional) loading in single-implant restorations. A literature search of the PubMed, Embase, Cochrane Library, Web of Science, and ClinicalTrials.gov databases was performed in January 2020. Only randomized clinical trials (RCTs) were included. (Source: International Journal of Oral and Maxillofacial Surgery)
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Poor Treatment Outcomes with Second-Line Chemotherapy in Advanced Synovial Sarcoma

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Via Oncology
CONCLUSION: Our exploratory study revealed that the response rate of second-line chemotherapy regimens for patients with synovial sarcoma was 9.4%. Therefore, there is an urgent need to develop more active therapeutic regimens for synovial sarcomas.PMID:35405680 | DOI:10.1159/000524500 (Source: Oncology)
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SEARCH FOR EXPERIMENTAL EVIDENCE OF DOSE-RATE AND WALL SCATTERING EFFECTS IN THE THERMOLUMINESCENCE RESPONSE OF LIF:MG,TI (TLD-100)

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Abstract
An experimental investigation into the possibility of dose-rate effects and wall scatter in the thermoluminescent response of LiF:Mg,Ti (TLD-100) was carried out. The investigation was motivated by theoretical simulations predicting the possible presence of dose-rate effects coupled with the lack of detailed experimental studies. The dose rate was varied by changing the source to sample distance, by the use of attenuators, sources of 137Cs of various activities, filtration and the construction of identical geometrical irradiators of Teflon and stainless steel. Four levels of dose in the linear dose response region were studied at 10−2 Gy, 1.5 × 10−2 Gy, 0.1 Gy and 0.5 Gy to avoid complications in interpretation due to supralinearity above 1 Gy. At the dose of 1.5 × 10−2 Gy, the dose rate was varied by five orders of magnitude from 4.9 × 10−3 Gy s−1 to 4.9 × 10− 8 Gy s−1. At the other levels of dose, a one to two orders of magnitude in dose rate was achieved. Within the measurement uncertainty of 5–10%, no dose-rate effects were observed in any of the experimental measurements and no changes in the shape of the glow curve were observed. The maximum wall scatter effect (Teflon to stainless steel) was measured at ~8% within the experimental uncertainty and well below expectations. The results are encouraging with respect to the accurate and reproducible use of LiF:Mg,Ti under various experimental conditions of irradiation.
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THE INFLUENCE OF LOW-DOSE OCCUPATIONAL RADIATION EXPOSURE ON PERIPHERAL BLOOD CELLS IN A COHORT OF CHINESE MEDICAL RADIATION WORKERS

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Abstract
Objectives
The study aims to assess the change of peripheral blood cell numbers following protracted low-dose radiation exposure among medical radiation workers.
Methods
A cohort of 375 Chinese medical workers were followed for 5 years (2015–19) and recorded the changes in blood cells and cumulative doses. T-test, least significant difference-T test, variance analysis and correlation analysis were utilized in this study.
Results
Compared with the control group, the white blood cells, hemoglobin counts and the ratio of eosinophils in the study group showed a downward trend. The differences in blood cells between groups were mainly found in the number of red blood cells. In a short cumulative time, such as 1 or 3 years, a correlation between the cumulative dose and the quantity of blood cells was detected, but not at 5 years.
Conclusions
There is no significant difference in the blood cell count s between different types of work, and the long-term cumulative dose has not been statistically correlated with the number of blood cells. So that the number of peripheral blood cells can no longer be used as a good indicator of radiation damage.
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DESIGN AND FABRICATION OF A PEDIATRIC THYROID PHANTOM FOR USE IN RADIO-IODINE UPTAKE MEASUREMENT, IMAGE QUALITY CONTROL AND DOSIMETRY

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Abstract
Estimating internal contamination from 131I for children in nuclear accidents is a crucial subject in the radiation protection field. Throughout this paper, an urgent and simple method was proposed for measuring 131I inside the pediatric thyroid gland by constructing a neck and thyroid phantom. For this purpose, CT scan images of healthy child's thyroids were obtained, and the sizes of different parts were determined by a 3D slicer image processing software. Girls with the body surface area between 0.95 and 1.05 were involved in this study. The fabricated phantom is composed of 5 cylindrical slabs of 2-cm thickness, and several small holes were constructed for TLD dosemeters near the thyroid gland and all other parts of the neck. The phantom was constructed utilizing a 3D printer with acrylonitrile butadiene styrene plastic. The thyroid phantom was filled with radioiodine-131, and calibration curves were plotted for contam ination estimation. A nodular thyroid phantom was also constructed. The nodular phantom or the resolution phantom has 4 removable parts containing cylindrical holes with diameters of 3, 6, 9 and 12 mm. These holes on the thyroid glands can be filled with different activities of radionuclides to serve as hot and cold spots for quality control of nuclear medicine images. The results show that the designed phantom is applicable in different fields such as nuclear image quality and resolution tests, dosimetry and iodine thyroid uptake estimation in nuclear medicine departments, and nuclear emergency monitoring.
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! # Ola via Alexandros G.Sfakianakis on Inoreader