Αρχειοθήκη ιστολογίου

Τετάρτη 5 Ιουνίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Metformin protects red blood cells against rotenone induced oxidative stress and cytotoxicity Shambhoo...
Metformin protects red blood cells against rotenone induced oxidative stress and cytotoxicityShambhoo Sharan Tripathi, Abhishek Kumar Singh, Farhan Akhtar, Ankita Chaudhary & Syed Ibrahim RizviReceived 02 Feb 2019, Accepted 13 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13813455.2019.1620288  Select Language▼Translator disclaimerAbstractContext: The anti-diabetic medicine metformin has been reported as an anti-ageing drug candidate as it mimics the benefits...
Αλέξανδρος Γ. Σφακιανάκης
now
Zizyphus lotus L. fruit attenuates obesity-associated alterations: in vivo mechanisms Meryem Berrichi,...
Zizyphus lotus L. fruit attenuates obesity-associated alterations: in vivo mechanismsMeryem Berrichi, Chahid Benammar, Babar Murtaza, Aziz Hichami, Meriem Belarbi & Naim Akhtar KhanReceived 08 Feb 2019, Accepted 15 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13813455.2019.1621349  Select Language▼Translator disclaimerAbstractContext: Zizyphus lotus L., ZL is a Mediterranean plant and widely consumed for its beneficial medicinal properties. Objective: We...
Αλέξανδρος Γ. Σφακιανάκης
now
Serum MiRNA-27a as potential diagnostic nucleic marker for breast cancer Menha Swellam ORCID Icon, Rasha...
Serum MiRNA-27a as potential diagnostic nucleic marker for breast cancerMenha Swellam ORCID Icon, Rasha F. K. Zahran ORCID Icon, Samar Ayman Ghonem & Camelia Abdel-MalakReceived 06 Nov 2018, Accepted 03 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/13813455.2019.1616765  Select Language▼Translator disclaimerAbstractBackground: Accumulating evidence reveals that microRNA 27a (miR 27a) is implicated in the pathogenesis of cancer. However, its diagnostic role...
Αλέξανδρος Γ. Σφακιανάκης
now
Investigation of the toxicological and inhibitory effects of some benzimidazole agents on acetylcholinesterase...
Investigation of the toxicological and inhibitory effects of some benzimidazole agents on acetylcholinesterase and butyrylcholinesterase enzymesFikret TürkanReceived 18 Mar 2019, Accepted 08 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/13813455.2019.1618341  Select Language▼Translator disclaimerAbstractBenzimidazole, an anthelmintic used in the manufacture of human and veterinary drugs, is an important heterocyclic compound. In this work, I investigated the effect...
Αλέξανδρος Γ. Σφακιανάκης
1m
MicroRNA-21 and microRNA-29a modulate the expression of collagen in dermal fibroblasts of patients with...
MicroRNA-21 and microRNA-29a modulate the expression of collagen in dermal fibroblasts of patients with systemic sclerosisSaeideh Jafarinejad-Farsangi, Farhad Gharibdoost, Ali Farazmand, Hoda Kavosi, Ahmadreza Jamshidi, Elham Karimizadeh,  show allReceived 27 Oct 2018, Accepted 18 May 2019, Published online: 03 Jun 2019Download citation  https://doi.org/10.1080/08916934.2019.1621856  Select Language▼Translator disclaimerAbstractMicroRNAs (miRNAs) are well-known candidates for modulating the dysregulated...
Αλέξανδρος Γ. Σφακιανάκης
1m
Dihydrotestosterone regulates oxidative stress and immunosuppressive cytokines in a female BALB/c mouse...
Dihydrotestosterone regulates oxidative stress and immunosuppressive cytokines in a female BALB/c mouse model of Graves' diseaseFengyi Zhao, Liping Wu, Yue Wang, Lianye Liu, Fei Yang, Yushi Sun,  show allReceived 28 Oct 2018, Accepted 18 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/08916934.2019.1621857  Select Language▼Translator disclaimerAbstractBackground: Graves' disease (GD) is an autoimmune disease that affects more women than men. In our previous study,...
Αλέξανδρος Γ. Σφακιανάκης
1m
Identification of acute myocardial infarction in elderly patients using optimized highly sensitive troponin...
Identification of acute myocardial infarction in elderly patients using optimized highly sensitive troponin I thresholdsBeatrice von Jeinsen , MD, Christoph Liebetrau , MD, Lars Palapies , MSc, Stergios Tzikas , MD, Tanja Zeller , PhD, Christoph Bickel , MD,  show allReceived 01 Nov 2018, Accepted 05 Apr 2019, Accepted author version posted online: 03 Jun 2019Download citation  https://doi.org/10.1080/1354750X.2019.1606276  Select Language▼Translator disclaimer Accepted author versionAbstractPurpose:...
Αλέξανδρος Γ. Σφακιανάκης
2m
Assessment of titanium dioxide nanoparticles toxicity via oral exposure in mice: effect of dose and...
Assessment of titanium dioxide nanoparticles toxicity via oral exposure in mice: effect of dose and particle sizeSanaa A. Ali, Maha Z. Rizk, Manal A. Hamed, Ezzat I. Aboul-Ela, Nagy S. El-Rigal, Hanan F. Aly &  show allReceived 12 Dec 2018, Accepted 02 May 2019, Accepted author version posted online: 17 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/1354750X.2019.1620336  Select Language▼Translator disclaimerAbstractObjective: The aim of the present work is...
Αλέξανδρος Γ. Σφακιανάκης
2m
Tumour expressions of hypoxic markers predict the response to neo-adjuvant chemotherapy in children...
Tumour expressions of hypoxic markers predict the response to neo-adjuvant chemotherapy in children with inoperable rhabdomyosarcomaMalgorzata Anna Krawczyk, Malgorzata Styczewska ORCID Icon, Ewa M. Sokolewicz, Michal Kunc ORCID Icon, Anna Gabrych, Aleksandra Fatyga,  show allReceived 22 Aug 2018, Accepted 05 Apr 2019, Accepted author version posted online: 17 Apr 2019, Published online: 31 May 2019Download citation  https://doi.org/10.1080/1354750X.2019.1606275  Select Language▼Translator disclaimerAbstractObjective:...
Αλέξανδρος Γ. Σφακιανάκης
3m
Cardiac troponins predict adverse clinical outcomes in stable coronary artery disease: a dose–response...
Cardiac troponins predict adverse clinical outcomes in stable coronary artery disease: a dose–response meta-analysis of prospective studiesYuehua Li, Hanjun Pei & Chenghui ZhouReceived 25 Nov 2018, Accepted 03 Apr 2019, Accepted author version posted online: 11 Apr 2019, Published online: 31 May 2019Download citation  https://doi.org/10.1080/1354750X.2019.1606277  Select Language▼Translator disclaimerAbstractBackground: Predictive value of cardiac tropnins (cTns) in stable coronary artery disease...
Αλέξανδρος Γ. Σφακιανάκης
3m
Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac...
Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrestJohannes Grand, Jesper Kjaergaard, Niklas Nielsen, Hans Friberg, Tobias Cronberg, John Bro-Jeppesen,  show allReceived 22 Feb 2019, Accepted 13 Apr 2019, Accepted author version posted online: 24 Apr 2019, Published online: 31 May 2019Download citation  https://doi.org/10.1080/1354750X.2019.1609580  Select Language▼Translator disclaimer Full Article   Figures & data  References   Citations ...
Αλέξανδρος Γ. Σφακιανάκης
3m
Occipital artery-anterior cerebral artery bypass with posterior auricular artery-middle cerebral artery...
Occipital artery-anterior cerebral artery bypass with posterior auricular artery-middle cerebral artery bypass for stenosis of the internal carotid artery bifurcationRyoko Niwa ORCID Icon, Toshikazu Kimura ORCID Icon & Shunsuke IchiReceived 01 Mar 2019, Accepted 14 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/02688697.2019.1620919  Select Language▼Translator disclaimerAbstractSuperficial temporal artery (STA)-middle cerebral artery (MCA) bypass, and STA-anterior...
Αλέξανδρος Γ. Σφακιανάκης
4m
Tuberculosis and leprosy associated with historical human population movements in Europe and beyond...
Tuberculosis and leprosy associated with historical human population movements in Europe and beyond – an overview based on mycobacterial ancient DNAHelen D. DonoghueReceived 13 Dec 2018, Accepted 13 May 2019, Accepted author version posted online: 28 May 2019Download citation  https://doi.org/10.1080/03014460.2019.1624822  Select Language▼Translator disclaimer Accepted author versionAbstractContext: Tuberculosis and leprosy are readily recognized in human remains due to their typical palaeopathology....
Αλέξανδρος Γ. Σφακιανάκης
8m
Massive transfusion in upper gastrointestinal bleeding: a new scoring system Yi-Chuan Chen ORCID Icon,...
Massive transfusion in upper gastrointestinal bleeding: a new scoring systemYi-Chuan Chen ORCID Icon, Chen-Ju Chuang, Kuang-Yu Hsiao, Leng-Chieh Lin, Ming-Szu Hung, Huan-Wen Chen &  show allReceived 20 Feb 2019, Accepted 29 Apr 2019, Accepted author version posted online: 03 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/07853890.2019.1615122  Select Language▼Translator disclaimerAbstractBackground: Massive transfusion in patients with upper gastrointestinal...
Αλέξανδρος Γ. Σφακιανάκης
9m
Validation of the Boston University staging system in AL amyloidosis Ross Tomlinson, Nicholas Matigian...
Validation of the Boston University staging system in AL amyloidosisRoss Tomlinson, Nicholas Matigian & Peter MolleeReceived 07 Feb 2019, Accepted 15 Apr 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/13506129.2019.1608941  Select Language▼Translator disclaimerAbstractObjectives: We aimed to externally validate Lilleness' et al. Boston University (BU) prognostic score that replaced NT-proBNP with brain natriuretic peptide (BNP), which will allow centres without...
Αλέξανδρος Γ. Σφακιανάκης
10m
Technology-Supported Interventions for Pregnant Women A Systematic Review Lee, Yaelim, PhD, RN; Cho,...
Technology-Supported Interventions for Pregnant WomenA Systematic ReviewLee, Yaelim, PhD, RN; Cho, Susie, MSN, RNCIN: Computers, Informatics, Nursing: May 31, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/CIN.0000000000000535Feature Article: PDF OnlyBUYPAPAbstractAuthor InformationArticle MetricsTechnology is deeply embedded in daily life; thus, more pregnant women seek information through the Internet and incorporate the use of technological devices during their pregnancies. This...
Αλέξανδρος Γ. Σφακιανάκης
11m
Clinical results of proton therapy reirradiation for recurrent nasopharyngeal carcinoma F. Dionisi,...
Clinical results of proton therapy reirradiation for recurrent nasopharyngeal carcinomaF. Dionisi, S. Croci, I. Giacomelli, M. Cianchetti, A. Caldara, M. Bertolin,  show allReceived 04 Feb 2019, Accepted 17 May 2019, Published online: 03 Jun 2019Download citation  https://doi.org/10.1080/0284186X.2019.1622772  Select Language▼Translator disclaimerAbstractBackground and purpose: Recurrent nasopharyngeal carcinoma (NPC) has limited curative treatment options. Reirradiation is the only potential definitive...
Αλέξανδρος Γ. Σφακιανάκης
11m
Hazardous Materials
The removal of pentavalent arsenic by graphite intercalation compound functionalized carbon foam from contaminated waterPublication date: 5 September 2019Source: Journal of Hazardous Materials, Volume 377Author(s): Pinki Rani Agrawal, Nahar Singh, Saroj Kumari, Sanjay R. DhakateAbstractIn the present investigation, Graphite intercalation compound (GIC) functionalized phenolic resin based carbon foam for removal of arsenic (As(V)) from contaminated water is developed by sacrificial template technique...
Αλέξανδρος Γ. Σφακιανάκης
12m
Impaired skin barrier function caused by reactive oxygen species in mice with colonic tumors Satoshi...
Impaired skin barrier function caused by reactive oxygen species in mice with colonic tumorsSatoshi Yokoyama, Keiichi Hiramoto & Yurika YamateReceived 12 Mar 2019, Accepted 20 May 2019, Accepted author version posted online: 28 May 2019Download citation  https://doi.org/10.1080/15569527.2019.1622559  Select Language▼Translator disclaimer Accepted author versionAbstractPurpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumors induced by azoxymethane...
Αλέξανδρος Γ. Σφακιανάκης
14m
Investigation the effect of Hypericum Perforatum on corneal alkali burns Uğur Yılmaz, Hüseyin Kaya,...
Investigation the effect of Hypericum Perforatum on corneal alkali burnsUğur Yılmaz, Hüseyin Kaya, Murat Turan, Ferda Bir & Barbaros ŞahinReceived 07 Jan 2019, Accepted 20 May 2019, Accepted author version posted online: 28 May 2019Download citation  https://doi.org/10.1080/15569527.2019.1622560   Select Language▼Translator disclaimer Full Article   Figures & data  References   Citations   Metrics   Reprints & Permissions  Get access Accepted author versionAbstractPurpose: To investigate...
Αλέξανδρος Γ. Σφακιανάκης
14m
Short term effects of intravitreal anti-vascular endothelial growth factor agents on cornea, anterior...
Short term effects of intravitreal anti-vascular endothelial growth factor agents on cornea, anterior chamber, and intraocular pressureGürcan Dogukan Arslan ORCID Icon, Dilek Guven, Abdurrahman Alpaslan Alkan, Hakan Kacar & Mehmet DemirReceived 15 Feb 2019, Accepted 04 May 2019, Accepted author version posted online: 15 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/15569527.2019.1616749  Select Language▼Translator disclaimerAbstractObjective: To evaluate short...
Αλέξανδρος Γ. Σφακιανάκης
15m
Phonological and phonetic impairment in aphasic speech: an acoustic study of the voice onset time of...
Phonological and phonetic impairment in aphasic speech: an acoustic study of the voice onset time of six French-speaking aphasic patientsClémence Verhaegen, Véronique Delvaux, Sophie Fagniart, Kathy Huet, Myriam Piccaluga & Bernard HarmegniesReceived 11 Dec 2018, Accepted 11 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/02699206.2019.1619095  Select Language▼Translator disclaimerABSTRACTThe aim of the present study is to contribute to the description of the...
Αλέξανδρος Γ. Σφακιανάκης
15m
How do persons with apraxia of speech deal with morphological stress in Spanish? A preliminary study...
How do persons with apraxia of speech deal with morphological stress in Spanish? A preliminary studyLorraine Baqué ORCID IconReceived 30 Jan 2019, Accepted 19 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/02699206.2019.1622155  Select Language▼Translator disclaimerABSTRACTEqual stress across adjacent syllables and extended syllable durations are amongst the most salient features of acquired Apraxia of Speech (AOS). Most studies conclude that there is a deficit...
Αλέξανδρος Γ. Σφακιανάκης
16m
evaluating unintelligible speech , Mirjam Öster Cattu Alves, Carina Ode & Sofia Strömbergsson ORCID...
evaluating unintelligible speech,Mirjam Öster Cattu Alves, Carina Ode & Sofia Strömbergsson ORCID IconReceived 16 Jan 2019, Accepted 20 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/02699206.2019.1622787  In this articleABSTRACTBackgroundMethodResultsDiscussionReferencesABSTRACTFormulae display:MathJax Logo?When investigating the interaction between speech production and intelligibility, unintelligible speech portions are often of particular interest. Therefore,...
Αλέξανδρος Γ. Σφακιανάκης
16m
Validation of the Swedish version of the LittlEARS® Auditory Questionnaire in children with normal hearing...
Validation of the Swedish version of the LittlEARS® Auditory Questionnaire in children with normal hearing – a longitudinal studyAnna Persson, Carmela Miniscalco ORCID Icon, Anette Lohmander ORCID Icon & Traci Flynn ORCID IconReceived 04 Apr 2019, Accepted 15 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/14992027.2019.1621397  AbstractObjective: To externally validate the Swedish version of the LittlEARS® Auditory Questionnaire (LEAQ) in children with normal...
Αλέξανδρος Γ. Σφακιανάκης
19m
Development of hearing standards for Ontario's Constable Selection System Christian Giguère, Chantal...
Development of hearing standards for Ontario's Constable Selection SystemChristian Giguère, Chantal Laroche, Véronique Vaillancourt & Sigfrid D. SoliReceived 04 Dec 2018, Accepted 05 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/14992027.2019.1617438  Select Language▼Translator disclaimerAbstractObjective: Develop valid and defensible hearing standards for Ontario constables to ensure safe and efficient operations.Design: Research involved three steps: (1)...
Αλέξανδρος Γ. Σφακιανάκης
20m
Electrophysiological characteristics in children with listening difficulties, with or without auditory...
Electrophysiological characteristics in children with listening difficulties, with or without auditory processing disorderTone Stokkereit Mattsson ORCID Icon, Ola Lind, Turid Follestad, Kjell Grøndahl, Wayne Wilson ORCID Icon, Jude Nicholas,  show allReceived 31 Aug 2018, Accepted 16 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/14992027.2019.1621396  Select Language▼Translator disclaimerAbstractObjective: To determine if the auditory middle latency responses...
Αλέξανδρος Γ. Σφακιανάκης
20m
Effects of noise and reverberation on speech recognition with variants of a multichannel adaptive dynamic...
Effects of noise and reverberation on speech recognition with variants of a multichannel adaptive dynamic range compression schemeVarsha H. Rallapalli & Joshua M. AlexanderReceived 29 Jun 2018, Accepted 04 May 2019, Published online: 29 May 2019Download citation  https://doi.org/10.1080/14992027.2019.1617902  Select Language▼Translator disclaimerAbstractObjective: Adaptive compression methods in hearing aids have been developed to maximise audibility while preserving temporal envelope modulations....
Αλέξανδρος Γ. Σφακιανάκης
21m
ALM Fluid Therapy Leads to 72 hr Survival After Hemorrhagic Shock a Model for Studying Differential...
ALM Fluid Therapy Leads to 72 hr Survival After Hemorrhagic Shocka Model for Studying Differential Gene Expression and Extending Biological TimeLetson, Hayley L., PhD; Morris, Jodie, PhD; Biros, Eric, PhD; Dobson, Geoffrey P., PhDJournal of Trauma and Acute Care Surgery: May 31, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/TA.0000000000002397Original Article: PDF OnlyBUYPAPAbstractAuthor InformationArticle MetricsBackground Non-compressible torso hemorrhage is a leading cause of traumatic...
Αλέξανδρος Γ. Σφακιανάκης
22m
Female Platelets Have Distinct Functional Activity Compared to Male Platelets Implications in Transfusion...
Female Platelets Have Distinct Functional Activity Compared to Male PlateletsImplications in Transfusion Practice and Treatment of Trauma-Induced CoagulopathyColeman, Julia R, MD, MPH1; Moore, Ernest E, MD2; Kelher, Marguerite R, MS1,3; Samuels, Jason M, MD1; Cohen, Mitchell J, MD2; Sauaia, Angela, MD, PhD1; Banerjee, Anirban, PhD1; Silliman, Christopher C, MD, PhD1,3; Peltz, Erik, DO1Journal of Trauma and Acute Care Surgery: May 31, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/TA.00000000000023982019...
Αλέξανδρος Γ. Σφακιανάκης
22m
Single-lateral cervical radiograph in pediatric trauma is equivalent to multiple views Lindholm, Erika...
Single-lateral cervical radiograph in pediatric trauma is equivalent to multiple viewsLindholm, Erika B, MD1; Malik, Archana, MD2,3; Parikh, Darshan, BA3; Mamdouhi, Tara, BA3; Alper, Lauren, BA3; Nanassy, Autumn, MA1; Ciullo, Sean, MD1,3; Arthur, L. Grier, MD1,3; Prasad, Rajeev, MD1,3; Herman, Martin, MD3,4; Grewal, Harsh, MD1,3Journal of Trauma and Acute Care Surgery: May 31, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/TA.0000000000002396PTS 2018 - Oral: PDF OnlyBUYPAPAbstractAuthor...
Αλέξανδρος Γ. Σφακιανάκης
23m
Effect of Mass Shootings on Gun Sales – A 20 Year Perspective Callcut, Rachael A., MD, MSPH1,2; Robles,...
Effect of Mass Shootings on Gun Sales – A 20 Year PerspectiveCallcut, Rachael A., MD, MSPH1,2; Robles, Anamaria M., MD1,2; Kornblith, Lucy Z., MD1,2; Plevin, Rebecca E., MD1,2; Mell, Matthew W., MD, MS3Journal of Trauma and Acute Care Surgery: May 31, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/TA.0000000000002399AAST 2018 Podium: PDF OnlyBUYPAPAbstractAuthor InformationArticle MetricsINTRODUCTION Granular data on gun sales has been historically difficult to obtain. In 2016, California...
Αλέξανδρος Γ. Σφακιανάκης
23m
Systematic Review of Oxygenation and Clinical Outcomes to Inform Oxygen Targets in Critically Ill Trauma...
Systematic Review of Oxygenation and Clinical Outcomes to Inform Oxygen Targets in Critically Ill Trauma PatientsDouin, David J., MD1; Schauer, Steven G., DO, MS2,3; Anderson, Erin L., RN1; Jones, Jacqueline, PhD, RN4; DeSanto, Kristen, MS1; Cunningham, Cord, MD, MPH3; Bebarta, Vikhyat S., MD1,2; Ginde, Adit A., MD, MPH1Journal of Trauma and Acute Care Surgery: May 30, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/TA.0000000000002392Systematic Review: PDF OnlyBUYPAPAbstractAuthor InformationArticle...
Αλέξανδρος Γ. Σφακιανάκης
23m
Gender-specific reference ranges of the vocal extent measure in young and healthy adults Marie-Louise...
Gender-specific reference ranges of the vocal extent measure in young and healthy adultsMarie-Louise Freymann, Philipp Mathmann, Julius Rummich, Constanze Müller, Konrad Neumann, Tadeus Nawka &  show allReceived 30 Jul 2018, Accepted 04 May 2019, Published online: 03 Jun 2019Download citation  https://doi.org/10.1080/14015439.2019.1617894  Select Language▼Translator disclaimerAbstractObjective: The recently developed vocal extent measure (VEM) quantifies a patient's vocal capacity as documented...
Αλέξανδρος Γ. Σφακιανάκης
24m
Risankizumab vs. ustekinumab for plaque psoriasis A. Al‐Janabi  Z.K. Jabbar‐Lopez  C.E.M. Griffiths ...
Risankizumab vs. ustekinumab for plaque psoriasisA. Al‐Janabi  Z.K. Jabbar‐Lopez  C.E.M. Griffiths  Z.Z.N. YiuFirst published: 03 June 2019 https://doi.org/10.1111/bjd.17954This summary relates to https://doi.org/10.1111/bjd.17624British Journal of Dermatology, 180, 1348–1351, June 2019ePDFPDFTOOLS SHARESummaryPsoriasis is a skin condition that causes a scaly, red rash which can vary from affecting only small areas of the body, such as the elbows and knees, to affecting a larger area of the body....
Αλέξανδρος Γ. Σφακιανάκης
25m
Pyrin mutations in complex hidradenitis suppurativa S. Vural  M. Gündoğdu  E. Gökpınar İli  C.D. Durmaz ...
Pyrin mutations in complex hidradenitis suppurativaS. Vural  M. Gündoğdu  E. Gökpınar İli  C.D. Durmaz  A. Vural  L. Steinmüller‐Magin  A. Kleinhempel L.M. Holdt  T. Ruzicka  K.A. Giehl  H.I. Ruhi  A. BoyvatFirst published: 03 June 2019 https://doi.org/10.1111/bjd.17956This summary relates to https://doi.org/10.1111/bjd.17466British Journal of Dermatology, 180, 1459–1467, June 2019ePDFPDFTOOLS SHARESummaryHidradenitis suppurativa (HS) is an inflammatory skin disease affecting approximately 1% of...
Αλέξανδρος Γ. Σφακιανάκης
26m
Treg lymphocytes and cutaneous viral infections S.S. Hampras  M. Tommasino  Y. Zhao  J.L. Messina ...
Treg lymphocytes and cutaneous viral infectionsS.S. Hampras  M. Tommasino  Y. Zhao  J.L. Messina  A.R. Giuliano  N.A. Fenske  B. Cherpelis  R.S. Hesterberg  A.A. Akuffo  R.P. Amorrortu  J. Balliu  L. Vijayan  T. Gheit  P.K. Epling‐Burnette  D.E. RollisonFirst published: 03 June 2019 https://doi.org/10.1111/bjd.17959This summary relates to https://doi.org/10.1111/bjd.17429British Journal of Dermatology, 180, 1449–1458, June 2019ePDFPDFTOOLS SHARESummaryApproximately three million non‐melanoma skin...
Αλέξανδρος Γ. Σφακιανάκης
27m
Pan‐dermatophyte PCR M. Walser  P.P. Bosshard First published: 03 June 2019 https://doi.org/10.1111/bjd.17958...
Pan‐dermatophyte PCRM. Walser  P.P. BosshardFirst published: 03 June 2019 https://doi.org/10.1111/bjd.17958This summary relates to https://doi.org/10.1111/bjd.17512British Journal of Dermatology, 180, 1489–1497, June 2019ePDFPDFTOOLS SHARESummaryDermatophytes are fungi that cause infections of the skin, hair and nails, called dermatophytosis or ringworm. These infections are among the most common skin diseases and affect up to 20% of the population at any given time. Current laboratory diagnosis...
Αλέξανδρος Γ. Σφακιανάκης
27m
Clinical and immunological features of pemphigus relapse I. Ujiie  H. Ujiie  H. Iwata  H. Shimizu First...
Clinical and immunological features of pemphigus relapseI. Ujiie  H. Ujiie  H. Iwata  H. ShimizuFirst published: 03 June 2019 https://doi.org/10.1111/bjd.17960This summary relates to https://doi.org/10.1111/bjd.17591British Journal of Dermatology, 180, 1498–1505, June 2019ePDFPDFTOOLS SHARESummaryPemphigus is a potentially fatal blistering skin disease. It is an autoimmune disease, meaning that the body's immune system, which normally fights off disease, in this case attacks healthy cells. The main...
Αλέξανδρος Γ. Σφακιανάκης
27m
Dermatological manifestations in Noonan syndrome D. Bessis  J. Miquel  E. Bourrat  C. Chiaverini  F....
Dermatological manifestations in Noonan syndromeD. Bessis  J. Miquel  E. Bourrat  C. Chiaverini  F. Morice‐Picard  C. Abadie  F. Manna  C. Baumann  M. Best  P. Blanchet  A.‐C. Bursztejn  Y. Capri  C. Coubes  F. Giuliano  S. Guillaumont … See all authorsFirst published: 03 June 2019 https://doi.org/10.1111/bjd.17961This summary relates to https://doi.org/10.1111/bjd.17404British Journal of Dermatology, 180, 1438–1448, June 2019ePDFPDFTOOLS SHARESummaryNoonan syndrome (NS) is a genetic disorder affecting...
Αλέξανδρος Γ. Σφακιανάκης
28m
Polyomaviruses of the skin: integrating molecular and clinical advances in an emerging class of viruses†...
Polyomaviruses of the skin: integrating molecular and clinical advances in an emerging class of viruses†J.C. Sheu  J. Tran  P.L. Rady  H. Dao Jr  S.K. Tyring  H.P. NguyenFirst published: 26 December 2018 https://doi.org/10.1111/bjd.17592 Cited by: 1†Funding sources None.‡Conflicts of interest None to declare.§J.C.S. and J.T. contributed equally to this work.¶ Plain language summary available onlineRead the full textePDFPDFTOOLS SHARESummaryBackgroundHuman polyomaviruses (HPyVs) are small, nonenveloped,...
Αλέξανδρος Γ. Σφακιανάκης
29m
Granulocyte–macrophage colony‐stimulating factor (GM‐CSF) as a therapeutic target in psoriasis: randomized,...
Granulocyte–macrophage colony‐stimulating factor (GM‐CSF) as a therapeutic target in psoriasis: randomized, controlled investigation using namilumab, a specific human anti‐GM‐CSF monoclonal antibody†K.A. Papp  M. Gooderham  R. Jenkins  R. Vender  J.C. Szepietowski  T. Wagner  B. Hunt  B. Souberbielle  on behalf of the NEPTUNE investigatorsFirst published: 12 September 2018 https://doi.org/10.1111/bjd.17195 Cited by: 2†Funding sources This study was funded and sponsored by Takeda Pharmaceutical Company‡Conflicts...
Αλέξανδρος Γ. Σφακιανάκης
30m
Detection of tissue factor in platelets: why is it so troublesome? Bjarne Østerud & Beth A. Bouchard...
Detection of tissue factor in platelets: why is it so troublesome?Bjarne Østerud & Beth A. BouchardReceived 03 Apr 2019, Accepted 09 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/09537104.2019.1624708  Select Language▼Translator disclaimerAbstractTissue factor (TF) is the most important trigger for the extrinsic coagulation pathway. TF, earlier denoted as thromboplastin, has always been a mystery since its discovery due to its abundant presence in most human...
Αλέξανδρος Γ. Σφακιανάκης
32m
Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet...
Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP)Rick Kapur ORCID Icon, Rukhsana Aslam, Edwin R. Speck, Johan M. Rebetz & John W. Semple ORCID IconReceived 09 Apr 2019, Accepted 21 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/09537104.2019.1624709  Select Language▼Translator disclaimerAbstractImmune thrombocytopenia (ITP) is an autoimmune bleeding...
Αλέξανδρος Γ. Σφακιανάκης
33m
The efficacy and safety of low-dose rituximab in immune thrombocytopenia: a systematic review and meta-analysis...
The efficacy and safety of low-dose rituximab in immune thrombocytopenia: a systematic review and meta-analysisYunjie Li, Yuye Shi, Zhengmei He, Qiuni Chen, Zhenyou Liu, Liang Yu &  show allReceived 24 Jan 2019, Accepted 16 Apr 2019, Published online: 03 Jun 2019Download citation  https://doi.org/10.1080/09537104.2019.1624706  Select Language▼Translator disclaimerAbstractRituximab has been frequently used as a second-line treatment for patients with immune thrombocytopenia (ITP). Recently, several...
Αλέξανδρος Γ. Σφακιανάκης
33m
Injured Older Adults Transported by Emergency Medical Services: One Year Outcomes by POLST Status Dana...
Injured Older Adults Transported by Emergency Medical Services: One Year Outcomes by POLST StatusDana Zive , MPH, Craig D. Newgard , MD, MPH, Amber Lin , MS, Aaron B. Caughey , MD, PhD, Susan Malveau , MS & Elizabeth Eckstrom , MD, MPHReceived 19 Mar 2019, Accepted 30 Apr 2019, Accepted author version posted online: 06 May 2019, Published online: 29 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1615154  Select Language▼Translator disclaimerAbstractBackground: Advance care...
Αλέξανδρος Γ. Σφακιανάκης
35m
Classification versus prediction of mortality risk using the SIRS and qSOFA scores in patients with...
Classification versus prediction of mortality risk using the SIRS and qSOFA scores in patients with infection transported by paramedicsDaniel J. Lane , PhD ORCID Icon, Steve Lin , MDCM, M.Sc & Damon C. Scales , MD, PhDReceived 15 Feb 2019, Accepted 22 May 2019, Accepted author version posted online: 29 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1624901  Select Language▼Translator disclaimer Accepted author versionAbstractObjective: Identifying patients with sepsis in the...
Αλέξανδρος Γ. Σφακιανάκης
35m
Catecholaminergic Polymorphic Ventricular Tachycardia: An Unusual Case of Fright-Induced Prehospital...
Catecholaminergic Polymorphic Ventricular Tachycardia: An Unusual Case of Fright-Induced Prehospital Cardiac Arrest in a Healthy 6-Year-Old ChildMichael Wilson , ACP, Steven Schwartz , MD, FRCPC & P. Richard Verbeek , MD, FRCPCAccepted author version posted online: 30 Apr 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1612972  Select Language▼Translator disclaimerAbstractCatecholaminergic Polymorphic Ventricular Tachycardia is a rare but often lethal...
Αλέξανδρος Γ. Σφακιανάκης
35m
Challenges of being prepared for pediatric emergencies Jost Kaufmann ORCID Icon & Michael Laschat...
Challenges of being prepared for pediatric emergenciesJost Kaufmann ORCID Icon & Michael LaschatReceived 17 May 2019, Accepted 30 May 2019, Accepted author version posted online: 31 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1626957 
Αλέξανδρος Γ. Σφακιανάκης
36m
Psychometric properties of the German Version of the Pediatric Evaluation of Disability Inventory (PEDI-G):...
Psychometric properties of the German Version of the Pediatric Evaluation of Disability Inventory (PEDI-G): A factor analysisChristina Schulze, André Meichtry, Julie Page & Anders KottorpReceived 09 Aug 2018, Accepted 08 May 2019, Published online: 02 Jun 2019Download citation  https://doi.org/10.1080/11038128.2019.1618392  Select Language▼Translator disclaimerAbstractBackground: Activities of daily living (ADL) are crucial for children because they enable them to participate in everyday life....
Αλέξανδρος Γ. Σφακιανάκης
41m
Everyday occupations prioritised by older adults participating in reablement. A cross-sectional study...
Everyday occupations prioritised by older adults participating in reablement. A cross-sectional studyHanne Tuntland, Ingvild Kjeken, Bjarte Folkestad, Oddvar Førland & Eva LangelandReceived 19 Nov 2018, Accepted 01 Apr 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/11038128.2019.1604800  Select Language▼Translator disclaimerAbstractBackground: Little knowledge exists regarding which occupations older adults prioritize as rehabilitation goals in reablement and what...
Αλέξανδρος Γ. Σφακιανάκης
41m
Higher adalimumab serum levels do not increase the risk of adverse events in patients with inflammatory...
Higher adalimumab serum levels do not increase the risk of adverse events in patients with inflammatory bowel diseaseNeeraj Narula, Brian Lauzon ORCID Icon & John K. MarshallReceived 03 Apr 2019, Accepted 15 May 2019, Published online: 30 May 2019Download citation  https://doi.org/10.1080/00365521.2019.1621367  Select Language▼Translator disclaimerAbstractBackground: The relationship between serum adalimumab concentrations and adverse events in patients with inflammatory bowel disease (IBD)...
Αλέξανδρος Γ. Σφακιανάκης
42m
Prognosis and prognostic factors in patients with advanced biliary tract cancer depending on its anatomical...
Prognosis and prognostic factors in patients with advanced biliary tract cancer depending on its anatomical locationByeong Geun Song, Jae Keun Park, Hye Seung Kim, Kyunga Kim, Joo Kyung Park, Kwang Hyuck Lee,  show allReceived 17 Feb 2019, Accepted 12 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/00365521.2019.1619827  Select Language▼Translator disclaimerAbstractObjective: Previous studies have revealed that biliary tract cancer (BTC) has different clinical characteristics...
Αλέξανδρος Γ. Σφακιανάκης
42m
Outcomes of infected pancreatic necrosis complicated with duodenal fistula in the era of minimally invasive...
Outcomes of infected pancreatic necrosis complicated with duodenal fistula in the era of minimally invasive techniquesDingcheng Shen ORCID Icon, Caihong Ning ORCID Icon, Gengwen Huang ORCID Icon & Zhiyong Liu ORCID IconReceived 09 Apr 2019, Accepted 12 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/00365521.2019.1619831  Select Language▼Translator disclaimerAbstractBackground: Duodenal fistula (DF) was reportedly thought to be the second most common type of...
Αλέξανδρος Γ. Σφακιανάκης
42m
Impact of anti-TNF-alpha therapy on colectomy rate and indications for colectomy in ulcerative colitis:...
Impact of anti-TNF-alpha therapy on colectomy rate and indications for colectomy in ulcerative colitis: comparison of two patient cohorts from 2005 to 2007 and from 2014 to 2016*Sara Kolehmainen, Anna Lepistö ORCID Icon & Martti Färkkilä ORCID IconReceived 22 Mar 2019, Accepted 12 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/00365521.2019.1620326  Select Language▼Translator disclaimerAbstractObjectives: The aim of this study is to assess the impact of biological...
Αλέξανδρος Γ. Σφακιανάκης
43m
Homeless Shelter Users and Their Experiences as EMS Patients: A Qualitative Study William J. Leggio...
Homeless Shelter Users and Their Experiences as EMS Patients: A Qualitative StudyWilliam J. Leggio , EdD, NRP ORCID Icon, Anthony Giguere , BS EMS, NRP, Carissa Sininger , BS EMS, NRP, Nicole Zlotnicki , BS EMS, NRP, Samuel Walker , BS EMS, NRP & Michael G. Miller , EdD, RN, NRPReceived 31 Jul 2018, Accepted 29 May 2019, Accepted author version posted online: 03 Jun 2019Download citation  https://doi.org/10.1080/10903127.2019.1626954  Select Language▼Translator disclaimer Accepted author versionAbstractIntroduction:...
Αλέξανδρος Γ. Σφακιανάκης
43m
US military medical evacuation and prehospital care of pediatric trauma casualties in Iraq and Afghanistan...
US military medical evacuation and prehospital care of pediatric trauma casualties in Iraq and AfghanistanJasonF. Naylor , DSc PA-C, Michael D. April , MD PhD MS, Erick E. Thronson , BSN, Guyon J. Hill , MD & Steven G. Schauer , DO MSReceived 15 Feb 2019, Accepted 29 May 2019, Accepted author version posted online: 03 Jun 2019Download citation  https://doi.org/10.1080/10903127.2019.1626956  Select Language▼Translator disclaimer Full Article   Figures & data  References   Citations   Metrics ...
Αλέξανδρος Γ. Σφακιανάκης
44m
Paramedic Transported Sepsis Cases in an Emergency Department Administrative Database Daniel J. Lane...
Paramedic Transported Sepsis Cases in an Emergency Department Administrative DatabaseDaniel J. Lane , PhD ORCID Icon, Ian E. Blanchard , M.Sc, ACP, Sheldon Cheskes , MD, Gerald Lazarenko , MD, Steve Lin , MDCM, MSc, Laurie J. Morrison , MD, MSc,  show allAccepted author version posted online: 02 May 2019, Published online: 31 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1611978  Select Language▼Translator disclaimerAbstractBackground: To evaluate a new strategy for identifying...
Αλέξανδρος Γ. Σφακιανάκης
44m
Critical Medication Shortages: Effective Strategies to Maintain Continuous Medication Availability for...
Critical Medication Shortages: Effective Strategies to Maintain Continuous Medication Availability for Emergency Medical ServicesDenise Whitfield , MD, MBA, Nichole Bosson , MD, MPH, Dorothy Habrat , DO, John Telmos , RN, Gary Watson , BSN, MBA, Marc Eckstein , MD, MPH,  show allReceived 04 Feb 2019, Accepted 08 May 2019, Accepted author version posted online: 14 May 2019, Published online: 31 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1619001  Select Language▼Translator disclaimerAbstractObjective:...
Αλέξανδρος Γ. Σφακιανάκης
45m
Critical Medication Shortages: Effective Strategies to Maintain Continuous Medication Availability for...
Critical Medication Shortages: Effective Strategies to Maintain Continuous Medication Availability for Emergency Medical ServicesDenise Whitfield , MD, MBA, Nichole Bosson , MD, MPH, Dorothy Habrat , DO, John Telmos , RN, Gary Watson , BSN, MBA, Marc Eckstein , MD, MPH,  show allReceived 04 Feb 2019, Accepted 08 May 2019, Accepted author version posted online: 14 May 2019, Published online: 31 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1619001  Select Language▼Translator disclaimerAbstractObjective:...
Αλέξανδρος Γ. Σφακιανάκης
45m
Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases Rachel Bo-Ming...
Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five CasesRachel Bo-Ming Liu , MD ORCID Icon, Sandy Bogucki , MD, PhD, Evie G. Marcolini, Connie Y. Yu, Charles R. Wira, Sharmin Kalam,  show allReceived 01 Aug 2018, Accepted 30 May 2019, Accepted author version posted online: 31 May 2019Download citation  https://doi.org/10.1080/10903127.2019.1626955  Select Language▼Translator disclaimer Accepted author versionAbstractBackground: Focused transthoracic echocardiography...
Αλέξανδρος Γ. Σφακιανάκης
46m
access to free medicinal cannabis , Mallory J E Loflin, Kimberly Babson, James Sottile, Sonya B Norman,...
access to free medicinal cannabis,Mallory J E Loflin, Kimberly Babson, James Sottile, Sonya B Norman, Staci Gruber ORCID Icon & Marcel O Bonn-MillerReceived 29 May 2018, Accepted 31 Mar 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/00952990.2019.1604722  Select Language▼Translator disclaimerABSTRACTBackground: With a rise in public pressure to increase veteran access to medicinal cannabis, free cannabis collectives for military veterans are proliferating across...
Αλέξανδρος Γ. Σφακιανάκης
48m
Cannabis legalization, regulation, & control: a review of key challenges for local, state, and provincial...
Cannabis legalization, regulation, & control: a review of key challenges for local, state, and provincial officialsJonathan P. Caulkins & Michelle L. KilbornReceived 31 Oct 2018, Accepted 23 Apr 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/00952990.2019.1611840  Select Language▼Translator disclaimer Full Article   Figures & data  References   Citations   Metrics   Reprints & Permissions  Get accessABSTRACTBackground: A number of countries are legalizing...
Αλέξανδρος Γ. Σφακιανάκης
49m
It is not necessary to take 10–12 core biopsy samples in men with PSA levels >20 ng/ml. We recommend taking 2, 4, and 6 samples for patients with PSA levels ≥100 ng/ml, 50–99.99 ng/ml, and 20–49.99 ng/ml, respectively.
Prostate cancer incidence and diagnosis in men with PSA levels >20 ng/ml: is it possible to decrease the number of biopsy cores?Alper Ozorak ORCID Icon, Ali Ersin Zumrutbas, Gungor Bingol, Yusuf Ozlulerden & Sefa Alperen OzturkReceived 09 Apr 2019, Accepted 14 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13685538.2019.1620204    Select Language▼Translator disclaimerAbstractObjectives: To define if less number of cores would be sufficient to diagnose prostate...
Αλέξανδρος Γ. Σφακιανάκης
50m
The prevalence and risk factors of prostatic calculi in Han Chinese: a cross-sectional study based on...
The prevalence and risk factors of prostatic calculi in Han Chinese: a cross-sectional study based on health examinationsJialin Meng ORCID Icon, Meng Zhang ORCID Icon, Shi-Yang Guan, Jun Zhou, Song Fan, Huaqing Hu &  show allReceived 02 Mar 2019, Accepted 14 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13685538.2019.1620203  Select Language▼Translator disclaimerAbstractPurpose: Prostatic calculi (PCal) are commonly present with prostate disease; we aim to...
Αλέξανδρος Γ. Σφακιανάκης
50m
Prostate cancer incidence and diagnosis in men with PSA levels >20 ng/ml: is it possible to decrease...
Prostate cancer incidence and diagnosis in men with PSA levels >20 ng/ml: is it possible to decrease the number of biopsy cores?Alper Ozorak ORCID Icon, Ali Ersin Zumrutbas, Gungor Bingol, Yusuf Ozlulerden & Sefa Alperen OzturkReceived 09 Apr 2019, Accepted 14 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13685538.2019.1620204  Select Language▼Translator disclaimerAbstractObjectives: To define if less number of cores would be sufficient to diagnose prostate...
Αλέξανδρος Γ. Σφακιανάκης
51m
Prevalence of testosterone deficiency among aging men with and without morbidities Juris Erenpreiss,...
Prevalence of testosterone deficiency among aging men with and without morbiditiesJuris Erenpreiss, Violeta Fodina, Rita Pozarska, Ksenija Zubkova, Alesja Dudorova & Anatolijs PozarskisReceived 28 Apr 2019, Accepted 18 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13685538.2019.1621832  Select Language▼Translator disclaimerAbstractIn this cross-sectional study 1852 men aged 40–70 years attending primary health care were invited to fill out the aging male symptoms...
Αλέξανδρος Γ. Σφακιανάκης
52m
Type 2 diabetes mellitus is more commonly well controlled in younger men compared to older men M. Zahid...
Type 2 diabetes mellitus is more commonly well controlled in younger men compared to older menM. Zahid Kocak ORCID Icon, Gulali Aktas, Tuba T. Duman, Burcin M. Atak, Satilmis Bilgin, Ozge Kurtkulagi &  show allReceived 10 May 2019, Accepted 18 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13685538.2019.1621833  Select Language▼Translator disclaimerAbstractAims: Type 2 Diabetes Mellitus (T2DM) is nearly epidemic worldwide. Greater skeletal muscle mass in men...
Αλέξανδρος Γ. Σφακιανάκης
52m
Three different urogenital carcinoma in an aging patient: a rare case presentation Caglar Yildirim ORCID...
Three different urogenital carcinoma in an aging patient: a rare case presentationCaglar Yildirim ORCID Icon, Musab Ali Kutluhan ORCID Icon, Aytac Sahin ORCID Icon, Ramazan Topakta ORCID Icon & Ahmet Urkmez ORCID IconReceived 16 May 2019, Accepted 18 May 2019, Published online: 01 Jun 2019Download citation  https://doi.org/10.1080/13685538.2019.1621834  Select Language▼Translator disclaimerAbstractUrogenital cancers are frequently encountered in daily practice. Prostate cancer is the second...
Αλέξανδρος Γ. Σφακιανάκης
53m
Early male aging or poor clinical consideration for males in IVF centers? An original study Ylenia Duca...
Early male aging or poor clinical consideration for males in IVF centers? An original studyYlenia Duca ORCID Icon, Aldo Eugenio Calogero ORCID Icon, Rosita Angela Condorelli ORCID Icon, Bruno Giammusso ORCID Icon, Sandro La Vignera ORCID Icon & Collaborators (Redox Group Catania)Received 05 Apr 2019, Accepted 09 May 2019, Published online: 28 May 2019Download citation  https://doi.org/10.1080/13685538.2019.1618260  Select Language▼Translator disclaimerAbstractThe Italian law 40/2004 allows the...
Αλέξανδρος Γ. Σφακιανάκης
53m
Clinical Nuclear Medicine
Re: Hepatocellular Carcinoma Mimicking Neuroendocrine Tumor Metastasis on 68Ga-DOTATATE PET/CTNo abstract availableEsthesioneuroblastoma on 68Ga DOTANOC PET/CTEsthesioneuroblastoma is a rare neoplasm arising from the neural crest cells of olfactory epithelium mostly in the nasal vault. We describe the 68Ga DOTANOC PET/CT findings of a 44-year-old woman who was operated for right nasal mass diagnosed as paraganglioma in the past and then develop a mass in the right nasal cavity after 2 years which...
Αλέξανδρος Γ. Σφακιανάκης
54m
Outcomes in surgically resectable oropharynx cancer treated with transoral robotic surgery versus definitive...
Outcomes in surgically resectable oropharynx cancer treated with transoral robotic surgery versus definitive chemoradiation☆Author links open overlay panelBhaswanthDhanireddyabeNicolas P.BurnettabSreejaSanampudiabCharles E.WootenabJonSlezakbcBrentSheltondLaurenSheltondAndrewShearerdSusanneArnoldaMaheshKudrimotiaThomas J.GalaaDepartment of Radiation Medicine, College of Medicine, University of Kentucky, Lexington, KY, United States of AmericabMarkey Cancer Center, University of Kentucky, Lexington,...
Αλέξανδρος Γ. Σφακιανάκης
58m
Age-Specific Distribution of Diagnosis and Outcomes of Children Admitted to ICUs A Population-Based...
Age-Specific Distribution of Diagnosis and Outcomes of Children Admitted to ICUsA Population-Based Cohort StudyJung, Minyoung, MD1; Park, Hyejeong, MSc1,2; Kang, Danbee, PhD2,3; Park, Jinkyeong, MD, PhD1; Jeon, Kyeongman, MD, PhD1; Chung, Chi Ryang, MD1; Yang, Jeong Hoon, MD, PhD1; Cho, Yang Hyun, MD1; Suh, Gee Young, MD, PhD1,2; Guallar, Eliseo, MD, DrPH2,4,5; Cho, Juhee, PhD2,3; Cho, Joongbum, MD, PhD1Pediatric Critical Care Medicine: May 31, 2019 - Volume Online First - Issue - pdoi: 10.1097/PCC.0000000000001978Online...
Αλέξανδρος Γ. Σφακιανάκης
59m
Temporal Variability in the Sampling of Vital Sign Data Limits the Accuracy of Patient State Estimation...
Temporal Variability in the Sampling of Vital Sign Data Limits the Accuracy of Patient State EstimationEytan, Danny, MD, PhD1,2; Jegatheeswaran, Anusha, MD, PhD3,4; Mazwi, Mjaye L., MBChB1,5; Assadi, Azadeh, RN(EC), MN-NP(Pediatrics)1; Goodwin, Andrew J., BEng1,6; Greer, Robert W., BEng, MSc1; Goodfellow, Sebastian D., PhD1; Laussen, Peter C., MBBS1,7Pediatric Critical Care Medicine: May 31, 2019 - Volume Online First - Issue - pdoi: 10.1097/PCC.0000000000001984Online Clinical Investigation: PDF...
Αλέξανδρος Γ. Σφακιανάκης
59m
Tracheal Size and Morphology on the Reconstructed CT Imaging Mizuguchi, Soichi, MD1,2; Motomura, Yoshitomo,...
Tracheal Size and Morphology on the Reconstructed CT ImagingMizuguchi, Soichi, MD1,2; Motomura, Yoshitomo, MD, PhD1,2; Maki, Jun, MD, PhD3; Baba, Rieko, MD1,2; Ichimiya, Yuko, MD1,2; Tokuda, Kentaro, MD, PhD3; Kaku, Noriyuki, MD, PhD1,2; Takada, Hidetoshi, MD, PhD1; Maehara, Yoshihiko, MD, PhD2; Ohga, Shouichi, MD, PhD1Pediatric Critical Care Medicine: May 31, 2019 - Volume Online First - Issue - pdoi: 10.1097/PCC.0000000000001996Online Clinical Investigation: PDF OnlyBUYSDCPAPAbstractAuthor InformationArticle...
Αλέξανδρος Γ. Σφακιανάκης
59m
Nutritional Status Deterioration Occurs Frequently During Children's ICU Stay Valla, Frédéric V., MD,...
Nutritional Status Deterioration Occurs Frequently During Children's ICU StayValla, Frédéric V., MD, MSc1,2; Baudin, Florent, MD, MSc1,3; Gaillard Le Roux, Bénédicte, MD4; Ford-Chessel, Carole, BD5; Gervet, Elodie, MD6; Giraud, Céline, MSc7; Ginhoux, Tiphanie, MSc8; Cour-Andlauer, Fleur, MD, MSc1; Javouhey, Etienne, MD, PhD1; Tume, Lyvonne, RN, PhD9,10Pediatric Critical Care Medicine: May 31, 2019 - Volume Online First - Issue - pdoi: 10.1097/PCC.0000000000001979Feature Article: PDF OnlyBUYSDCPAPAbstractAuthor...
Αλέξανδρος Γ. Σφακιανάκης
1h
Are tattoos associated with negative health‐related outcomes and risky behaviors? Karoline Mortensen...
Are tattoos associated with negative health‐related outcomes and risky behaviors?Karoline Mortensen PhD  Michael T. French PhD  Andrew R. Timming PhDFirst published: 24 January 2019 https://doi.org/10.1111/ijd.14372Read the full textePDFPDFTOOLS SHAREAbstractBackgroundTattoos have reached broadening mainstream acceptance. Medical professional societies have noted that tattoos may co‐occur with high risk behaviors.MethodsUsing a variety of statistical models applied to a sample of 2,008 adults residing...
Αλέξανδρος Γ. Σφακιανάκης
1h
Urticarial vasculitis (UV) , Eosinophilic infiltration
Eosinophilic infiltration: an under‐reported histological finding in urticarial vasculitisKambiz Kamyab MD  Seyedeh Zahra Ghodsi MD  Alireza Ghanadan MD  Jafar Taghizadeh MD  Shiva Karimi MD  Maryam Nasimi MDFirst published: 28 January 2019 https://doi.org/10.1111/ijd.14387Funding source: none.Conflict of interest: noneRead the full textePDFPDFTOOLS SHAREAbstractBackgroundUrticarial vasculitis (UV) is a clinicopathologic entity in which skin lesions resemble urticaria clinically but last more than...
Αλέξανδρος Γ. Σφακιανάκης
1h
Lichen planus‐like keratosis: clinicopathological evaluation of 1366 cases Vladimir Vincek MD, PhD First...
Lichen planus‐like keratosis: clinicopathological evaluation of 1366 casesVladimir Vincek MD, PhDFirst published: 18 December 2018 https://doi.org/10.1111/ijd.14358I, Vladimir Vincek, want to declare that I don't have any affiliation or significant financial involvement in any organization or entity with a direct financial interest in the subject matter or materials discussed in the manuscript.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundLichen planus‐like keratosis (LPLK) is a frequent...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cutaneous leishmaniasis: an evolving disease with ancient roots Maelle Saliba MD  Awss Shalhoub MD ...
Cutaneous leishmaniasis: an evolving disease with ancient rootsMaelle Saliba MD  Awss Shalhoub MD  Suad Taraif MD  Asif Loya MD  Mohammad A. Houreih MD  Rana El Hajj PhD  Ibrahim Khalifeh MDFirst published: 10 April 2019 https://doi.org/10.1111/ijd.14451Funding: None.Conflicts of interest: None.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundCutaneous leishmaniasis (CL) remains a prioritized neglected tropical disease. CL novel presentations call for updating its features.MethodsA multiregional...
Αλέξανδρος Γ. Σφακιανάκης
1h
In-transit melanoma metastases. Testori A1, Ribero S2, Bataille V3. Author information 1 Divisione di...
In-transit melanoma metastases.Testori A1, Ribero S2, Bataille V3.Author information1Divisione di Chirurgia Dermatoncologica, Istituto Europeo di Oncologia, Milano, Italy. Electronic address: alessandro.testori@ieo.it.2Dermatologia, Dipartimentto di Scienze mediche, Università di Torino, Italy.3West Herts NHS Trust, London, UK; Mount Vernon Cancer Centre, Northwood, UK.AbstractIn transit metastases (ITM) from extremity or trunk melanomas are subcutaneous or cutaneous lymphatic deposits of melanoma...
Αλέξανδρος Γ. Σφακιανάκης
1h
Necrotizing infundibular crystalline folliculitis: a clinicopathological study. Denisjuk N1, Hilty N,...
Necrotizing infundibular crystalline folliculitis: a clinicopathological study.Denisjuk N1, Hilty N, Pfaltz M, Kempf W.Author information1Kempf and Pfaltz, Histological Diagnostics, Zürich, Switzerland.AbstractBACKGROUND:Necrotizing infundibular crystalline folliculitis (NICF) is a folliculocentric disorder associated with filamentous crystalline deposits, enclosed by parakeratotic columns within the partly necrotic follicular ostium and infundibulum. There are only very few data published about...
Αλέξανδρος Γ. Σφακιανάκης
1h
inea capitis (TC) is a dermatophyte infection of the scalp hair follicles and intervening skin
Management of tinea capitis in childhoodAntoni Bennassar and Ramon GrimaltAuthor information Article notes Copyright and License information DisclaimerDept of Dermatology, Hospital Clinic, University of Barcelona, Barcelona, SpainCorrespondence: Ramon Grimalt, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain, Fax +34 937 800011, Email ude.bu@tlamirgReceived 2010 Jul 12This article has been cited by other articles in PMC.Go to:AbstractTinea capitis (TC) is a common dermatophyte infection affecting...
Αλέξανδρος Γ. Σφακιανάκης
1h
Maculopapular cutaneous mastocytosis (MPCM) is the clinical variant of cutaneous mastocytosis (CM) most frequently observed in adults, usually within the context of an indolent systemic mastocytosis (SM). Few cases of an unusual form of MPCM affecting the intertriginous areas have been described. Here, we present a case of SM with intertriginous cutaneous involvement in a woman with hematologic disease.
Intertriginous maculopapular mastocytosis in a patient with acute myeloid leukemiaMaría Herrero-Moyano, MD,∗ Tania Marusia Capusan, MD, Alejandra Pérez-Plaza, MD, Almudena Godoy, MD, andJavier Sánchez-Perez, MDAuthor information Article notes Copyright and License information DisclaimerHospital Universitario de La Princesa, Madrid, SpainMaría Herrero-Moyano: moc.liamg@onayomorerrehairam∗Correspondence to: María Herrero-Moyano, MD, Hospital Universitario de La Princesa, Servicio de Dermatología, Calle...
Αλέξανδρος Γ. Σφακιανάκης
1h
Intralesional radiofrequency treatment for venous lake Kavita Poonia MD  Anand Kumar MD  Gurvinder P....
Intralesional radiofrequency treatment for venous lakeKavita Poonia MD  Anand Kumar MD  Gurvinder P. Thami MDFirst published: 16 April 2019 https://doi.org/10.1111/ijd.14308Conflict of interest: Nil.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundVenous lakes are asymptomatic, cosmetically unacceptable vascular malformations commonly present over the lips. Most of the lesions do not warrant any therapeutic intervention.ObjectiveWe herein report a 20‐year‐old male patient with venous lake who...
Αλέξανδρος Γ. Σφακιανάκης
1h
Chemotherapy‐induced skin toxicity and capillary leak syndrome Manrup K. Hunjan MBChB  Somaira Nowsheen...
Chemotherapy‐induced skin toxicity and capillary leak syndromeManrup K. Hunjan MBChB  Somaira Nowsheen PhD  Alvaro J. Ramos‐Rodriguez MD  Alina G. Bridges MD  Julia S. Lehman MD  Shahrukh K. Hashmi MD  Rokea A. el‐Azhary MD, PhDFirst published: 07 March 2019 https://doi.org/10.1111/ijd.14392Funding: None.Conflicts of interest: None.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundThe occurrence of chemotherapy‐related adverse cutaneous reactions in the setting of capillary leak syndrome (CLS)...
Αλέξανδρος Γ. Σφακιανάκης
1h
Understanding the role of cutaneous allergy testing in anogenital dermatoses: a retrospective evaluation...
Understanding the role of cutaneous allergy testing in anogenital dermatoses: a retrospective evaluation of contact sensitization in anogenital dermatosesCatherine C. Foley MB, BCh  Siobhan White BSN  Subha Merry BSN  Una Nolan BSN  Blaithin Moriarty MB, BCh  Brian Kirby MB, BCh  Paul Collins MB, BCh  Aoife Lally MB, BChFirst published: 06 February 2019 https://doi.org/10.1111/ijd.14360Read the full textePDFPDFTOOLS SHAREAbstractBackgroundPatients with anogenital symptoms may delay before seeking...
Αλέξανδρος Γ. Σφακιανάκης
1h
CD8‐positive lymphomatoid papulosis (type D): Some lesions may lack CD30 expression and overlap histologically...
CD8‐positive lymphomatoid papulosis (type D): Some lesions may lack CD30 expression and overlap histologically with mycosis fungoidesOlivia C. Simo BS  Simon J. Warren MD  Lawrence Mark MD  Kristin Hoffmann MD  Ahmed K. Alomari MDFirst published: 06 December 2018 https://doi.org/10.1111/ijd.14309Read the full textePDFPDFTOOLS SHAREAbstractBackgroundCD8+ lymphomatoid papulosis is frequently indistinguishable histopathologically from primary cutaneous aggressive epidermotropic CD8+ T‐cell lymphoma...
Αλέξανδρος Γ. Σφακιανάκης
1h
Finasteride as treatment for hair loss, hirsutism, and various other dermatologic conditions in women
The efficacy and use of finasteride in women: a systematic reviewAllison C. Hu BA  Lance W. Chapman MD, MBA  Natasha A. Mesinkovska MD, PhDFirst published: 03 January 2019 https://doi.org/10.1111/ijd.14370 Cited by: 1Conflict of Interest: None declared.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundPhysicians are beginning to use finasteride as treatment for hair loss, hirsutism, and various other dermatologic conditions in women. However, the reported efficacy and use of finasteride in the...
Αλέξανδρος Γ. Σφακιανάκης
1h
Balanitis xerotica obliterans: a review of diagnosis and management Olivia A. Charlton BASc, MBBS, MPH ...
Balanitis xerotica obliterans: a review of diagnosis and managementOlivia A. Charlton BASc, MBBS, MPH  Saxon D. Smith MBChB, MHL, PhD, FACDFirst published: 12 October 2018 https://doi.org/10.1111/ijd.14236Conflicts of interest: none.Funding: none.Read the full textePDFPDFTOOLS SHAREAbstractBalanitis xerotica obliterans (BXO), or penile lichen sclerosus, is a progressive sclerosing inflammatory dermatosis of the glans penis and foreskin. It is associated with significant morbidity and may result in...
Αλέξανδρος Γ. Σφακιανάκης
1h
Gardner‐Diamond syndrome (GDS) is a rare psychodermatological condition characterized by the formation of spontaneous, painful skin lesions that develop into ecchymosis following episodes of severe physiological or psychological stress.
Gardner‐Diamond syndrome: a systematic review of treatment options for a rare psychodermatological disorderMegan E. Block BS  Jenna L. Sitenga BS  Michael Lehrer MD  Peter T. Silberstein MDFirst published: 20 September 2018 https://doi.org/10.1111/ijd.14235Funding: None.Conflicts of interest disclosure: None declared.Human and animal rights: This study does not involve human or animal subjectsRead the full textePDFPDFTOOLS SHAREAbstractGardner‐Diamond syndrome (GDS) is a rare psychodermatological...
Αλέξανδρος Γ. Σφακιανάκης
1h
Controversies in off‐label prescriptions in dermatology: the perspective of the patient, the physician,...
Controversies in off‐label prescriptions in dermatology: the perspective of the patient, the physician, and the pharmaceutical companiesKatlein França MD, PhD  Sergio Litewka MDFirst published: 31 August 2018 https://doi.org/10.1111/ijd.14222Funding: None.Conflicts of interest: None.Read the full textePDFPDFTOOLS SHAREAbstractThe term "off‐label drug use" involves the prescription of medications for unapproved indications or in unapproved dosage, dosage form, or route of administration. Off‐label...
Αλέξανδρος Γ. Σφακιανάκης
1h
Gray Matter Structural Network Disruptions in Survivors of Acute Lymphoblastic Leukemia with Chemotherapy...
Gray Matter Structural Network Disruptions in Survivors of Acute Lymphoblastic Leukemia with Chemotherapy TreatmentPublication date: Available online 4 June 2019Source: Academic RadiologyAuthor(s): Longsheng Wang, Liwei Zou, Qi Chen, Lianzi Su, Jiajia Xu, Ru Zhao, Yanqi Shan, Qing Zhang, Zhimin Zhai, Xijun Gong, Hong Zhao, Fangbiao Tao, Suisheng ZhengObjectivesNeuroimaging studies of acute lymphoblastic leukemia (ALL) during chemotherapy treatment have shown alterations in structure, function, and...
Αλέξανδρος Γ. Σφακιανάκης
1h
Localization of Axillary Lymph Nodes in the Treatment of Invasive Breast Cancer Publication date: June...
Localization of Axillary Lymph Nodes in the Treatment of Invasive Breast CancerPublication date: June 2019Source: Academic Radiology, Volume 26, Issue 6Author(s): Ryan W. Woods, Melissa S. Camp, Nicholas J. Durr, Susan C. HarveyInvasive breast cancer is a common disease, and the most common initial site of metastatic disease are the axillary lymph nodes. As the standard of care shifts towards less invasive surgery in the axilla for patients with invasive breast cancer, techniques have been developed...
Αλέξανδρος Γ. Σφακιανάκης
1h
Radiology
Gray Matter Structural Network Disruptions in Survivors of Acute Lymphoblastic Leukemia with Chemotherapy TreatmentPublication date: Available online 4 June 2019Source: Academic RadiologyAuthor(s): Longsheng Wang, Liwei Zou, Qi Chen, Lianzi Su, Jiajia Xu, Ru Zhao, Yanqi Shan, Qing Zhang, Zhimin Zhai, Xijun Gong, Hong Zhao, Fangbiao Tao, Suisheng ZhengObjectivesNeuroimaging studies of acute lymphoblastic leukemia (ALL) during chemotherapy treatment have shown alterations in structure, function, and...
Αλέξανδρος Γ. Σφακιανάκης
1h
Molecular Immunology
S100A9 maintains myeloid-derived suppressor cells in chronic sepsis by inducing miR-21 and miR-181bPublication date: August 2019Source: Molecular Immunology, Volume 112Author(s): Tuqa Alkhateeb, Ajinkya Kumbhare, Isatou Bah, Dima Youssef, Zhi Q. Yao, Charles E. McCall, Mohamed El GazzarAbstractMyeloid-derived suppressor cells (MDSC) expand during sepsis, suppress both innate and adaptive immunity, and promote chronic immunosuppression, which characterizes the late/chronic phase of sepsis. We previously...
Αλέξανδρος Γ. Σφακιανάκης
1h
OnabotulinumtoxinA and incobotulinumtoxinA are two botulinum toxin A (BoNT‐A) formulations commonly used in esthetic medicine
Two different types of botulinum toxins: Is there a difference in efficacy and longevity?Debraj Shome MD, FRCS, FACS, MBA  Rinky Kapoor MD  Stuti Khare MDFirst published: 28 May 2019 https://doi.org/10.1111/jocd.12949Read the full textePDFPDFTOOLS SHAREAbstractBackgroundOnabotulinumtoxinA and incobotulinumtoxinA are two botulinum toxin A (BoNT‐A) formulations commonly used in esthetic medicine. They are distinguished by whether complexing proteins are included with the active neurotoxin. While OnabotulinumtoxinA...
Αλέξανδρος Γ. Σφακιανάκης
1h
Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen...
Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women"Mayoura Keophiphath PhD  Christophe Courbière PharmD  Léana Manzato MSc  Irène Lamour MSc Emmanuelle Gaillard MScFirst published: 28 May 2019 https://doi.org/10.1111/jocd.12998Read the full textePDFPDFTOOLS SHAREAbstractBackgroundMiliacin, the main triterpenoid from millet, is known to stimulate keratinocyte metabolism and proliferation. Polar lipids are able to form vesicles with...
Αλέξανδρος Γ. Σφακιανάκης
1h
Lentinan inhibits oxidative stress and inflammatory cytokine production induced by benzo(a)pyrene in...
Lentinan inhibits oxidative stress and inflammatory cytokine production induced by benzo(a)pyrene in human keratinocytesYusha Zi BS  Biao Jiang BS  Congfen He PhD  Lei Liu PhDFirst published: 28 May 2019 https://doi.org/10.1111/jocd.13005Read the full textePDFPDFTOOLS SHAREAbstractBackgroundBenzo(a)pyrene, a major environmental pollutant, is known to accelerate skin aging through oxidative stress, increase the production of inflammatory mediators, and cause skin cancer. Lentinan, prepared from Lentinus...
Αλέξανδρος Γ. Σφακιανάκης
1h
Unraveling the molecular and cellular mechanisms of stretch marks Desirée C. Schuck PhD  Camila M. de...
Unraveling the molecular and cellular mechanisms of stretch marksDesirée C. Schuck PhD  Camila M. de Carvalho PhD  Mariane P. J. Sousa BSc  Priscila P. Fávero PhD Airton A. Martin PhD  Márcio Lorencini PhD  Carla A. Brohem PhDFirst published: 27 May 2019 https://doi.org/10.1111/jocd.12974Read the full textePDFPDFTOOLS SHAREAbstractBackgroundStriae distensae, commonly known as stretch marks, are cutaneous lesions that accompany the hormonal upheavals of the major stages of life: puberty and pregnancy....
Αλέξανδρος Γ. Σφακιανάκης
1h
Assessing patient satisfaction among ABHRS surgeons: Opportunities to improve Amir A. Hakimi BS  Jonathan...
Assessing patient satisfaction among ABHRS surgeons: Opportunities to improveAmir A. Hakimi BS  Jonathan P. Yasmeh MS  David S. Foulad MDFirst published: 27 May 2019 https://doi.org/10.1111/jocd.13001Read the full textePDFPDFTOOLS SHAREAbstractBackground/ObjectiveOnline physician‐rating websites are being increasingly used by patients to gauge physicians' quality of service. The objective of this study is to assess the impact of residency training background of hair restoration surgeons and to identify...
Αλέξανδρος Γ. Σφακιανάκης
1h
Influence of hyper‐harmonized fullerene water complex on collagen quality and skin function Suzana Miljkovic...
Influence of hyper‐harmonized fullerene water complex on collagen quality and skin functionSuzana Miljkovic PhD  Branislava Jeftic PhD  Dusan Sarac PhD  Valentina Matovic MSc  Marija Slavkovic MSc  Djuro Koruga PhDFirst published: 29 May 2019 https://doi.org/10.1111/jocd.12999Read the full textePDFPDFTOOLS SHAREAbstractBackgroundFullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules.ObjectivesThis...
Αλέξανδρος Γ. Σφακιανάκης
1h
Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential...
Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential indicationsKritarth Naman Singh MBBS, MD  Saiprasad Patil MBBS, MD  Hanmant Barkate MBBS, MDFirst published: 29 May 2019 https://doi.org/10.1111/jocd.13019Read the full textePDFPDFTOOLS SHAREAbstractAstaxanthin is a naturally occurring ketocarotenoid which has been found to have numerous biological functions, with its strong antioxidant property being the prominent feature. The compound has attracted...
Αλέξανδρος Γ. Σφακιανάκης
1h
Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical...
Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical studyMuhammet Avcil PhD  Gokhan Akman PhD  Jens Klokkers PhD  Dohyeon Jeong PhD  Ayhan Çelik PhDFirst published: 28 May 2019 https://doi.org/10.1111/jocd.13009Funding information: This study was funded by Imperial Bioscience Ltd.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundAging skin is a gradual physiological process associated with functional and structural changes of the skin. Both intrinsic...
Αλέξανδρος Γ. Σφακιανάκης
1h
Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in...
Beyond sun protection factor: An approach to environmental protection with novel mineral coatings in a vehicle containing a blend of skincare ingredientsEric F. Bernstein MD, MSE  Harry W. Sarkas PhD  Patricia Boland BA  Deborah BoucheFirst published: 28 May 2019 https://doi.org/10.1111/jocd.13007SECTIONSePDFPDFTOOLS SHAREAbstractBackgroundPremature skin aging results from exposure to a range of environmental factors, primarily ultraviolet radiation, but also high‐energy visible light in the blue...
Αλέξανδρος Γ. Σφακιανάκης
1h
Serum TWEAK in acne vulgaris: An unknown soldier Abd El‐Aziz Ibrahim El‐Taweel MD  Rehab Mohammed Salem...
Serum TWEAK in acne vulgaris: An unknown soldierAbd El‐Aziz Ibrahim El‐Taweel MD  Rehab Mohammed Salem MD  Amira Mohamed Noureldin Abdelrahman MD  Basma Abd El‐Kafy Mohamed MBBCHFirst published: 28 May 2019 https://doi.org/10.1111/jocd.13011Read the full textePDFPDFTOOLS SHAREAbstractBackgroundTWEAK is an inflammatory cytokine which is involved in the development of many inflammatory disorders.AimsThis study aimed to evaluate serum levels of TWEAK in patients with acne vulgaris.Subjects and MethodsThis...
Αλέξανδρος Γ. Σφακιανάκης
1h
Use of an anteriorly based ventral tongue flap to reconstruct the lower vermilion following early‐stage...
Use of an anteriorly based ventral tongue flap to reconstruct the lower vermilion following early‐stage cancer ablationZhao‐hui Yang DDS, MD  Bin Zhou DDS, PhD  Jiang‐long Zhong DDS  Wei‐liang Chen DDS, MD, MBAFirst published: 31 May 2019 https://doi.org/10.1111/jocd.13020Read the full textePDFPDFTOOLS SHAREAbstractBackgroundReconstruction of lower vermilion defects is surgically challenging.AimsThis study evaluated whether lower vermilion defects can be repaired using tongue flaps, and the reconstructive...
Αλέξανδρος Γ. Σφακιανάκης
1h
Youth versus femininity: What are we truly trying to achieve? Sabrina Guillen Fabi MD, FAAD, FAACS ...
Youth versus femininity: What are we truly trying to achieve?Sabrina Guillen Fabi MD, FAAD, FAACS  Matthew Willett MDFirst published: 29 May 2019 https://doi.org/10.1111/jocd.13012The views expressed in this article are those of the author and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the US Government.Read the full textePDFPDFTOOLS SHAREAbstractThe desire for a more youthful appearance is that for which men and women often...
Αλέξανδρος Γ. Σφακιανάκης
1h
Efficacy of high‐intensity focused ultrasound in facial and neck rejuvenation Zehra Aşiran Serdar MD ...
Efficacy of high‐intensity focused ultrasound in facial and neck rejuvenationZehra Aşiran Serdar MD  Ezgi Aktaş Karabay MD  Aslı Tatlıparmak MD  Berna Aksoy MDFirst published: 29 May 2019 https://doi.org/10.1111/jocd.13008CorrespondenceEzgi Aktaş Karabay, Faculty of Medicine, Department of Dermatology, Bahçeşehir University, Batman Sok. No: 66, 34734 Kadıköy, Istanbul, Turkey.Email: ezgiaktasmd@gmail.comRead the full textePDFPDFTOOLS SHAREAbstractBackgroundHigh‐intensity focused ultrasound (HIFU)...
Αλέξανδρος Γ. Σφακιανάκης
1h
Use of combined fractional carbon dioxide laser and fractional microneedle radiofrequency for the treatment...
Use of combined fractional carbon dioxide laser and fractional microneedle radiofrequency for the treatment of acne scars: A retrospective analysis of 1‐month treatment outcome on scar severity and patient satisfactionAslı Tatlıparmak MD  Berna Aksoy MD  Ladan R. Shishehgarkhaneh MD  Gonca Gökdemir MD  Erol Koç MDFirst published: 29 May 2019 https://doi.org/10.1111/jocd.13004Read the full textePDFPDFTOOLS SHAREAbstractBackgroundAcne scars lead to social and psychological problems for patients, and...
Αλέξανδρος Γ. Σφακιανάκης
1h
Microbial Adjuncts for Food Allergen Immunotherapy AbstractPurpose of Review Food allergen immunotherapy...
Microbial Adjuncts for Food Allergen ImmunotherapyAbstractPurpose of ReviewFood allergen immunotherapy may benefit from adjunct therapies to enhance safety and efficacy. We review preclinical studies investigating the effects of probiotics and other microbial-based interventions on oral tolerance, describe the human clinical trial evidence thus far for microbial adjuncts, and discuss steps for translating research findings in this area to clinical therapy.Recent FindingsMurine studies support that...
Αλέξανδρος Γ. Σφακιανάκης
1h
Role of Allogeneic Hematopoietic Stem Cell Transplant for Chronic Granulomatous Disease (CGD): a Report...
Role of Allogeneic Hematopoietic Stem Cell Transplant for Chronic Granulomatous Disease (CGD): a Report of the United States Immunodeficiency NetworkAbstractPurposeChronic granulomatous disease (CGD) is a primary immunodeficiency for which allogeneic hematopoietic stem cell transplant (HSCT) offers potential cure. Direct comparison of HSCT to non-HSCT management in the North American population was performed to identify clinical factors associated with overall survival (OS) and transplant-related...
Αλέξανδρος Γ. Σφακιανάκης
1h
Evaluating Penicillin Allergies Without Skin Testing : Direct oral amoxicillin challenges in low-risk individuals are well accepted by patients and a safe and effective part of penicillin allergy delabeling.
Allergy Asthma Proc. 2019 Jan 1;40(1):57-61. doi: 10.2500/aap.2019.40.4184.Direct oral amoxicillin challenge without preliminary skin testing in adult patients with allergy and at low risk with reported penicillin allergy.Kuruvilla M1, Shih J1, Patel K1, Scanlon N2.Author information1From the Department of Allergy/Immunology, Emory University, Atlanta, Georgia.2Department of Internal Medicine, Emory University, Atlanta, Georgia.AbstractIntroduction: Ten percent of hospitalized patients report penicillin...
Αλέξανδρος Γ. Σφακιανάκης
1h
Contributions of Innate Lymphoid Cells in Chronic Rhinosinusitis AbstractPurpose of Review To review...
Contributions of Innate Lymphoid Cells in Chronic RhinosinusitisAbstractPurpose of ReviewTo review innate lymphoid cells (ILCs) and their role in chronic rhinosinusitis (CRS).Recent FindingsThe immune system consists of the innate and adaptive response. Until the recognition of ILCs, chronic inflammatory diseases were characterized by cytokines linked only to T helper cells. However, these immune responses are now described more broadly to include contributions from both the innate and adaptive immunity....
Αλέξανδρος Γ. Σφακιανάκης
1h
Th9 Cells in Allergic Disease AbstractPurposes of Review Th9 cells are recognized as a novel subset...
Th9 Cells in Allergic DiseaseAbstractPurposes of ReviewTh9 cells are recognized as a novel subset of effector T helper cells that preferentially produce IL-9. Here, we provide a current update on the reports related to the function of Th9 cells in allergic inflammatory diseases.Recent FindingsThe effector Th9 cells differentiating from naïve T helper cells have recently been identified. Because of accumulating findings of Th9 cells in many inflammatory diseases, including allergic diseases, diverse...
Αλέξανδρος Γ. Σφακιανάκης
1h
Allergy and Asthma
Vitamin D and Otitis MediaAbstractPurpose of ReviewTo examine the relationship between vitamin D and otitis media.Recent FindingsVitamin D deficiency has been associated with several respiratory diseases, including otitis media. Vitamin D supplementation may reduce the risk of otitis media. This relationship may be explained by vitamin D supporting the immune system by upregulating antimicrobial peptides which are effective against otopathogens and biofilm formation, supporting a less inflammatory...
Αλέξανδρος Γ. Σφακιανάκης
1h
Clinical Immunology
iPLA 2 Activation Mediates Granular Exocytosis and Corrects Microbicidal Defects in ROS-Deficient and CGD Human NeutrophilsAbstractPurposeThe ubiquitous calcium–independent phospholipase A2 enzyme (iPLA2) is inhibited by calmodulin binding and known to be responsible for phospholipid remodeling housekeeping functions including granule exocytosis–associated membrane fusion in normal human neutrophils. We evaluate in human neutrophils the iPLA2 secretagogue effects using normal neutrophils, where reactive...
Αλέξανδρος Γ. Σφακιανάκης
1h
Improved identification of patients with oligometastatic clear cell renal cell carcinoma with PSMA-targeted...
Improved identification of patients with oligometastatic clear cell renal cell carcinoma with PSMA-targeted 18 F-DCFPyL PET/CTAbstractObjectiveComplete surgical resection of metastatic sites has been shown to prolong survival in select patients with oligometastatic RCC. This treatment strategy is dependent upon the accurate characterization of a patient's extent of disease. The objective of this study was to explore the utility of PSMA-targeted 18F-DCFPyL PET/CT in patients with presumed oligometastatic...
Αλέξανδρος Γ. Σφακιανάκης
1h
Measurement of cerebral vascular reserves with I-123 IMP SPECT without an arterial input function using...
Measurement of cerebral vascular reserves with I-123 IMP SPECT without an arterial input function using the microsphere model and radiopharmaceutical dose calibrationAbstractObjectivesCerebral vascular reserve (CVR) is an important indicator for the management of and therapy for cerebral arterial occlusive disease (CAOD). Vasodilatory function is measured using the standard IMP-ARG method. The IMP autoradiography (IMP-ARG) method employed here uses a standardized input function, which was derived...
Αλέξανδρος Γ. Σφακιανάκης
1h
The use of 3′-deoxy-3′- 18 F-fluorothymidine (FLT) PET in the assessment of long-term survival in breast...
The use of 3′-deoxy-3′- 18 F-fluorothymidine (FLT) PET in the assessment of long-term survival in breast cancer patients treated with neoadjuvant chemotherapyAbstractObjectiveTo assess the role of serial FLT-PET scans during early neoadjuvant treatment as a prognostic marker of response to treatment and survival.MethodsThis study is a prospective cohort study which draws from a larger original study which examined the utility of FLT-PET imaging across multiple cancers. Our cohort consisted of patients...
Αλέξανδρος Γ. Σφακιανάκης
1h
Novel 3D heart left ventricle muscle segmentation method for PET-gated protocol and its verification...
Novel 3D heart left ventricle muscle segmentation method for PET-gated protocol and its verificationAbstractObjectiveThe aim of this study was to propose and verify a universal method of left ventricular myocardium segmentation, able to operate on heart gated PET data with different sizes, shapes and uptake distributions. The proposed method can be classified as active model method and is based on the BEAS (B-spline Explicit Active Surface) algorithm published by Barbosa et al. The method was implemented...
Αλέξανδρος Γ. Σφακιανάκης
1h
Potential utility of bone scan in cranial bone flap osteomyelitis AbstractObjective Currently, the...
Potential utility of bone scan in cranial bone flap osteomyelitisAbstractObjectiveCurrently, the diagnosis of bone flap osteomyelitis (BFO) remains a challenge for medical imaging. The present study aimed to identify predictive scintigraphic patterns of BFO.MethodsThis retrospective study reviewed planar bone scan of patients with suspected BFO between 2010, and 2016. A total of 15 patients were included. Final diagnosis of BFO was obtained by histological and bacteriological documentation. Eight...
Αλέξανδρος Γ. Σφακιανάκης
1h
Characterization of the binding of tau imaging ligands to melanin-containing cells: putative off-target-binding...
Characterization of the binding of tau imaging ligands to melanin-containing cells: putative off-target-binding siteAbstractObjectiveAmyloid-β plaques and neurofibrillary tangles composed of tau protein are the neuropathological hallmarks of Alzheimer's disease. In recent years, marked progress has been made in Alzheimer's disease research using tau ligands for positron emission tomography (PET). However, the issue of off-target binding, that is, the binding of ligands to regions without tau pathology,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft...
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2AbstractObjectiveL-type amino acid transporter 1 (LAT1) is strongly expressed on the cell membrane in various types of human cancer cells, while being minimally expressed in normal or inflammatory tissues. Therefore, LAT1-targeting PET tracers have been developed for cancer-specific imaging. The purpose of this study was to study the distribution of two LAT1-targeting...
Αλέξανδρος Γ. Σφακιανάκης
1h
dynamic 18 F-fluorodeoxyglucose positron emission tomography/computed tomography for evaluating lymph...
dynamic 18 F-fluorodeoxyglucose positron emission tomography/computed tomography for evaluating lymph node metastasis in patients with lung cancer: a prospective studyAbstractObjectiveWe assessed the diagnostic capacity of dynamic fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and dual-time-point (DTP) PET/CT to explore the optimal scan timing for nodal staging in lung cancer.MethodsThirty-four patients with lung cancer underwent dynamic and consecutive...
Αλέξανδρος Γ. Σφακιανάκης
1h
Nuclear Medicine
Preliminary results of biodistribution and dosimetric analysis of [ 68 Ga]Ga-DOTA ZOL : a new zoledronate-based bisphosphonate for PET/CT diagnosis of bone diseasesAbstractObjectivePre-clinical studies with gallium-68 zoledronate ([68Ga]Ga-DOTAZOL) have proposed it to be a potent bisphosphonate for PET/CT diagnosis of bone diseases and diagnostic counterpart to [177Lu]Lu-DOTAZOL and [225Ac]Ac-DOTAZOL. This study aims to be the first human biodistribution and dosimetric analysis of [68Ga]Ga-DOTAZOL.MethodsFive...
Αλέξανδρος Γ. Σφακιανάκης
1h
BMP4 mutations in tooth agenesis and low bone mass Publication date: July 2019 Source: Archives of...
BMP4 mutations in tooth agenesis and low bone massPublication date: July 2019Source: Archives of Oral Biology, Volume 103Author(s): Miao Yu, Hao Wang, Zhuangzhuang Fan, Chencheng Xie, Haochen Liu, Yang Liu, Dong Han, Sing-Wai Wong, Hailan FengAbstractObjectiveTo identify an uncommon genetic cause of tooth agenesis (TA) by utilizing whole exome sequencing (WES) and targeted Sanger sequencing in a cohort of 120 patients with isolated TA.DesignOne deleterious mutation in the gene encoding bone morphogenetic...
Αλέξανδρος Γ. Σφακιανάκης
2h
Liposome-coated nano doxorubicin induces apoptosis on oral squamous cell carcinoma CAL-27 cells Publication...
Liposome-coated nano doxorubicin induces apoptosis on oral squamous cell carcinoma CAL-27 cellsPublication date: July 2019Source: Archives of Oral Biology, Volume 103Author(s): Ehab S. Abd El-Hamid, Amira M. Gamal-Eldeen, Abdelrahman M. Sharaf EldeenAbstractObjectiveThis study aims to investigate the apoptotic effect of Doxorubicin and its nano-formulated form (Doxil) on oral squamous cell carcinoma CAL-27 cells.DesignCell viability using MTT assay, mode of cell death using fluorescence analysis,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Effects of Candida albicans infection on defense effector secretion by human oral mucosal epithelial...
Effects of Candida albicans infection on defense effector secretion by human oral mucosal epithelial cellsPublication date: July 2019Source: Archives of Oral Biology, Volume 103Author(s): Fan Huang, Yuefeng Song, Wei Chen, Qin Liu, Qiong Wang, Weida Liu, Xiang Wang, Wenmei WangAbstractObjectiveThe aim of this study was to investigate the effects of Candida albicans on the production of defense effector molecules by human oral mucosal epithelial cells in vitro.DesignImmortalized human oral mucosal...
Αλέξανδρος Γ. Σφακιανάκης
2h
Salivary gland metabolism in an animal model of chronic kidney disease Publication date: August 2019...
Salivary gland metabolism in an animal model of chronic kidney diseasePublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): R.A. Carvalho, A.C. Romero, F.K. Ibuki, F.N. NogueiraAbstractObjectiveThe aim of this study was to determine the effects of experimental CKD into the metabolism of parotid and submandibular glands of rats. CKD was induced by 5/6 nephrectomy.DesignSerum analyses of BUN (Blood Urea Nitrogen) and creatinine concentrations were performed. Major salivary...
Αλέξανδρος Γ. Σφακιανάκης
2h
Staircase-pattern neonatal line in human deciduous teeth is associated with tooth type Publication...
Staircase-pattern neonatal line in human deciduous teeth is associated with tooth typePublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Jaana Hurnanen, Matti Sillanpää, Marja-Leena Mattila, Eliisa Löyttyniemi, Carsten Witzel, Jaana RautavaAbstractObjectiveThe staircase (Sc) pattern enamel microstructure is an expression of an impaired ameloblast function. It has been reported to appear in the neonatal line (NNL), the accentuated stria evincing live birth in deciduous...
Αλέξανδρος Γ. Σφακιανάκης
2h
Applications of the oral microbiome in personalized dentistry Publication date: August 2019 Source: Archives...
Applications of the oral microbiome in personalized dentistryPublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Georgios N. Belibasakis, Nagihan Bostanci, Philip D. Marsh, Egija ZauraAbstractObjectiveIn the era of personalized medicine, it is imperative that oral health is integrated into this concept. The oral cavity fosters a highly individualized microbiome that has evolved to promote oral health, and which exists in a dynamic balance with the host. Microecological...
Αλέξανδρος Γ. Σφακιανάκης
2h
Whole metagenomic shotgun sequencing of the subgingival microbiome of diabetics and non-diabetics with...
Whole metagenomic shotgun sequencing of the subgingival microbiome of diabetics and non-diabetics with different periodontal conditionsPublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Roberto Farina, Mattia Severi, Alberto Carrieri, Elena Miotto, Silvia Sabbioni, Leonardo Trombelli, Chiara ScapoliAbstractObjectiveThe aim of this study was to use high-resolution whole metagenomic shotgun sequencing to characterize the subgingival microbiome of patients with/without...
Αλέξανδρος Γ. Σφακιανάκης
2h
Pellicle From Wikipedia, the free encyclopedia Jump to navigationJump to search Look up pellicle in...
PellicleFrom Wikipedia, the free encyclopediaJump to navigationJump to searchLook up pellicle in Wiktionary, the free dictionary.Pellicle may refer to:Pellicle (biology), a thin layer supporting the cell membrane in various protozoaPellicle mirror, a thin plastic membrane which may be used as a beam splitter or protective cover in optical systemsPellicle (dental), the thin layer of salivary glycoproteins deposited on the teeth of many species through normal biologic processesPellicle, the protective...
Αλέξανδρος Γ. Σφακιανάκης
2h
Pellicle (dental), the thin layer of salivary glycoproteins deposited on the teeth of many species through normal biologic processes
Activity and distribution pattern of enzymes in the in-situ pellicle of childrenPublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Susann Hertel, Annika Schulz, Roman Lang, Thomas Hofmann, Belinda König, Matthias Hannig, Christian HannigAbstractObjectiveThis study investigated, for the first time, pellicle enzymes with respect to their activity, distribution and fluorescence pattern in children with different caries experience.DesignIn-situ pellicles were collected...
Αλέξανδρος Γ. Σφακιανάκης
2h
Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial...
Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial painPublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Hayes Wong, Brian E. CairnsAbstractObjectiveThis study investigated whether local intramuscular injection of non-psychoactive cannabinoids, cannabidiol (CBD), cannabinol (CBN), cannabichromene (CBC) and their combinations can decrease nerve growth factor (NGF)-induced masticatory muscle sensitization in female...
Αλέξανδρος Γ. Σφακιανάκης
2h
High CD3+ lymphocytes, low CD66b+ neutrophils, and scarce tumor budding in the invasive front of lip...
High CD3+ lymphocytes, low CD66b+ neutrophils, and scarce tumor budding in the invasive front of lip squamous cell carcinomasPublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Karine Duarte da Silva, Patrícia Carlos Caldeira, Alessandro Menna Alves, Ana Carolina Uchoa Vasconcelos, Ana Paula Neutzling Gomes, Maria Cássia Ferreira de Aguiar, Sandra Beatriz Chaves TarquinioAbstractObjectiveThis study aimed to evaluate tumor budding (TB) and quantify the neutrophilic...
Αλέξανδρος Γ. Σφακιανάκης
2h
Face detection in the operating room: comparison of state-of-the-art methods and a self-supervised...
Face detection in the operating room: comparison of state-of-the-art methods and a self-supervised approachAbstractPurposeFace detection is a needed component for the automatic analysis and assistance of human activities during surgical procedures. Efficient face detection algorithms can indeed help to detect and identify the persons present in the room and also be used to automatically anonymize the data. However, current algorithms trained on natural images do not generalize well to the operating...
Αλέξανδρος Γ. Σφακιανάκης
2h
Toward an automatic preoperative pipeline for image-guided temporal bone surgery AbstractPurpose Minimally...
Toward an automatic preoperative pipeline for image-guided temporal bone surgeryAbstractPurposeMinimally invasive surgery is often built upon a time-consuming preoperative step consisting of segmentation and trajectory planning. At the temporal bone, a complete automation of these two tasks might lead to faster interventions and more reproducible results, benefiting clinical workflow and patient health.MethodsWe propose an automatic segmentation and trajectory planning pipeline for image-guided interventions...
Αλέξανδρος Γ. Σφακιανάκης
2h
Catheter localization in 3D ultrasound using voxel-of-interest-based ConvNets for cardiac intervention...
Catheter localization in 3D ultrasound using voxel-of-interest-based ConvNets for cardiac interventionAbstractPurposeEfficient image-based catheter localization in 3D US during cardiac interventions is highly desired, since it facilitates the operation procedure, reduces the patient risk and improves the outcome. Current image-based catheter localization methods are not efficient or accurate enough for real clinical use.MethodsWe propose a catheter localization method for 3D cardiac ultrasound (US)....
Αλέξανδρος Γ. Σφακιανάκης
2h
Uncertainty-aware performance assessment of optical imaging modalities with invertible neural networks...
Uncertainty-aware performance assessment of optical imaging modalities with invertible neural networksAbstractPurposeOptical imaging is evolving as a key technique for advanced sensing in the operating room. Recent research has shown that machine learning algorithms can be used to address the inverse problem of converting pixel-wise multispectral reflectance measurements to underlying tissue parameters, such as oxygenation. Assessment of the specific hardware used in conjunction with such algorithms,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Automatic self-gated 4D-MRI construction from free-breathing 2D acquisitions applied on liver images...
Automatic self-gated 4D-MRI construction from free-breathing 2D acquisitions applied on liver imagesAbstractPurposeMRI slice reordering is a necessary step when three-dimensional (3D) motion of an anatomical region of interest has to be extracted from multiple two-dimensional (2D) dynamic acquisition planes, e.g., for the construction of motion models used for image-guided radiotherapy. Existing reordering methods focus on obtaining a spatially coherent reconstructed volume for each time. However,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Position-based modeling of lesion displacement in ultrasound-guided breast biopsy AbstractPurpose Although...
Position-based modeling of lesion displacement in ultrasound-guided breast biopsyAbstractPurposeAlthough ultrasound (US) images represent the most popular modality for guiding breast biopsy, malignant regions are often missed by sonography, thus preventing accurate lesion localization which is essential for a successful procedure. Biomechanical models can support the localization of suspicious areas identified on a preoperative image during US scanning since they are able to account for anatomical...
Αλέξανδρος Γ. Σφακιανάκης
2h
Oral Biology
High CD3+ lymphocytes, low CD66b+ neutrophils, and scarce tumor budding in the invasive front of lip squamous cell carcinomasPublication date: August 2019Source: Archives of Oral Biology, Volume 104Author(s): Karine Duarte da Silva, Patrícia Carlos Caldeira, Alessandro Menna Alves, Ana Carolina Uchoa Vasconcelos, Ana Paula Neutzling Gomes, Maria Cássia Ferreira de Aguiar, Sandra Beatriz Chaves TarquinioAbstractObjectiveThis study aimed to evaluate tumor budding (TB) and quantify the neutrophilic...
Αλέξανδρος Γ. Σφακιανάκης
2h
Computer Assisted Radiology and Surgery
EasyLabels: weak labels for scene segmentation in laparoscopic videosAbstractPurposeWe present a different approach for annotating laparoscopic images for segmentation in a weak fashion and experimentally prove that its accuracy when trained with partial cross-entropy is close to that obtained with fully supervised approaches.MethodsWe propose an approach that relies on weak annotations provided as stripes over the different objects in the image and partial cross-entropy as the loss function of a...
Αλέξανδρος Γ. Σφακιανάκης
2h
Microbiology
Flavobacterium viscosus sp. nov. and Flavobacterium tangerina sp. nov., from Primates FecesAbstractStrains YIM 102796T and YIM 102701-2T were isolated from the feces of Macaca mulatta and Hylobates hoolock, respectively, living in the Yunnan Wild Animal Park, Yunnan province of China. The two strains were Gram-stain-negative, non-gliding, produced flexirubin pigments, non-flagellated and aerobic bacteria. The 16S rRNA gene-based phylogenetic analysis indicate that both YIM 102796T and YIM 102701-2T are...
Αλέξανδρος Γ. Σφακιανάκης
2h

Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480

Hazardous Materials

The removal of pentavalent arsenic by graphite intercalation compound functionalized carbon foam from contaminated water

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Pinki Rani Agrawal, Nahar Singh, Saroj Kumari, Sanjay R. Dhakate

Abstract

In the present investigation, Graphite intercalation compound (GIC) functionalized phenolic resin based carbon foam for removal of arsenic (As(V)) from contaminated water is developed by sacrificial template technique followed by carbonization at 1000 °C in N2. The GICCF adsorbent is characterised by scanning electron microscope (SEM) for morphological study, X-ray diffraction (XRD) patterns explains the phase information and interlayer spacing of the adsorbent, whereas Fourier Transform Infrared Spectroscopy (FTIR) and X-ray Photoelectron Spectroscopy (XPS) gives the information about surface functionality and mechanism of adsorption of As(V) over the surface of adsorbent. The time data is fitted well in pseudo second order kinetics and follows multilinear nature of intra-particle diffusion model. The adsorption nature of adsorbent and adsorbate is explained by Langmuir isotherm better than Freundlich isotherm, Temkin isotherm, and D-R isotherm. The adsorption capacity of adsorbent is 62.5 μgg−1, which is calculated by Langmuir isotherm. Arsenic removal by GICCF is taken place within two hrs up to acceptable limit. The proposed GICCF can be regenerated after treating with 0.1 M HNO3 and 0.1 M HCl solution and it can be used for multiple times.

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Simultaneous arsenic and fluoride removal using {201}TiO2–ZrO2: Fabrication, characterization, and mechanism

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Yaqin Yu, Zhen Zhou, Zhaoxia Ding, Meimei Zuo, Jiemin Cheng, Chuanyong Jing

Abstract

The coexistence of arsenic (As) and fluoride (F) in drinking water is an urgent environmental issue that causes increasing public concerns. The need for effective simultaneous removal of As and F has motived great research efforts. Herein, a novel {201}TiO2–ZrO2 composite was synthesized and its application mechanism was explored. Batch adsorption experiments show that the As(III), As(V), and F adsorption followed the pseudo-second-order kinetics with the Langmuir adsorption capacity at 58.5, 21.6, and 13.1 mg/g, respectively. EXAFS and in situ ATR-FTIR results suggested that TiO2 surface sites were occupied by As(III) and As(V) in bidentate binuclear structures, and ZrO2 sites preferentially adsorbed As(III) and F in monodentate mononuclear configurations. This molecular structure obtained in the mono-adsorption system was integrated with the charge distribution multisite surface complexation model to accurately predict the As and F co-existing adsorption behaviors. The results in competitive adsorption, regeneration, and application evidenced that the {201}TiO2-ZrO2composite is a promising adsorbent for simultaneous As and F removal.

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Waste-wood-derived biochar cathode and its application in electro-Fenton for sulfathiazole treatment at alkaline pH with pyrophosphate electrolyte

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Fengxia Deng, Hugo Olvera-Vargas, Orlando Garcia-Rodriguez, Yingshi Zhu, Jizhou Jiang, Shan Qiu, Jixian Yang

Abstract

For the first time, a biomass-derived porous carbon cathode (WDC) was fabricated via a facile one-step pyrolysis of recovered wood-waste without any post-treatment. The WDC along with pyrophosphate (PP) as electrolyte were used in electro-Fenton (EF) at pH 8 for sulfathiazole (STZ) treatment. The H2O2 accumulation capacity of WDC was optimized via the following parameters: pyrolysis temperature, applied current and electrolyte. Results showed that the WDC cathode prepared at 900 °C achieved the highest H2O2 accumulation (13.80 mg L−1 in 3 h) due to its larger electroactive surface area (28.81 cm2). Interestingly, it was found that PP decreased the decomposition rate of H2O2 in solution as compared to conventional electrolyte, which resulted in higher H2O2 accumulation. PP allowed operating EF at pH of 8 due to the formation of Fe2+-PP complexes in solution. Moreover, Fe2+-PP was able to activate oxygen to produce OH. In this way, the degradation of STZ took place through four main pathways: 1) via OH from the Fe2+-PP complex, 2) via OH from EF reactions, 3) via surface OH at the boron doped diamond electrode (BDD) and 4) via SO4- from BDD activation. Finally, microtox tests revealed that some toxic intermediates were generated during WDC/BDD/PP EF treatment, but they were removed at the end of the process.

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Immunotoxicity of four nanoparticles to a marine bivalve species, Tegillarca granosa

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Shanjie Zha, Jiahuan Rong, Xiaofan Guan, Yu Tang, Yu Han, Guangxu Liu

Abstract

The increasing application of nanomaterials drives the unintentional release of nanoparticles (NPs) into the ocean, which may pose a potential threat to marine organisms. It has been demonstrated that exposure to NPs could chanllenge the immune responses of marine species. However, the affecting mechanism behind remains poorly understood. In this study, the immunotoxic impacts and the mechanisms underpinning the effects of four major NPs, including nZnO, nFe2O3, nCuO, and carbon nanotube (MWCNT), were investigated in blood clam, Tegillarca granosa. The results showed that exposure to tested NPs resulted in reduced total counts, altered cell composition, and constrained phagocytic activities of haemocytes. The intracellular contents of reactive oxygen species (ROS) and the degree of DNA damage of haemocytes were significantly induced, whereas the haemocyte viability was suppressed. Furthermore, NP exposures led to significant increases in the in vivo contents of neurotransmitters. Down-regulations of the immune- and neurotransmitter-related genes were detected as well. Our data suggest that NP exposures hampered the immune responses of blood clams most likely through (1) inducing ROS, causing DNA damage, and reducing cell viability of haemocytes, (2) altering the in vivocontents of neurotransmitters, and (3) affecting the expression of immune- and neurotransmitter-related genes.

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The enhanced photocatalytic properties of MnO2/g-C3N4 heterostructure for rapid sterilization under visible light

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Beibei Wu, Yuan Li, Kun Su, Lei Tan, Xiangmei Liu, Zhenduo Cui, Xianjin Yang, Yanqin Liang, Zhaoyang Li, Shengli Zhu, Kelvin Wai Kwok Yeung, Shuilin Wu

Abstract

Herein, a heterostructure based on MnO2 and g-C3N4 was constructed on the surface of metallic Ti implants, in which MnO2 favored the transfer and separation of free charges to enhance the photoconversion efficiency of g-C3N4 by 21.11%. Consequently, the yield of ROS was promoted significantly, which denatured protein and damaged DNA to kill bacteria efficiently. In addition, glutathione (GSH, l-γ-glutamyl-l-cysteinyl-glycine) defending oxidative stress in bacteria, was oxidized by MnO2 in the hybrid coating once the bacterial membrane was disrupted by ROS. Hence, after visible light irradiation for 20 min, MnO2/g-C3N4 coating exhibited superior disinfection efficacy of 99.96% and 99.26% against S. aureus and E. coli severally. This work provided a practical sterilization strategy about MnO2/g-C3N4 systems through the synergistic effects of enhanced photodynamic antibacterial therapy and oxidization effect of MnO2 with great biosafety, in which MnO2 enhanced the photocatalyst property of g-C3N4 to generate more ROS and deplete GSH to improve antibacterial efficiency. It will bring more insight into rapid and highly effective disinfection and antibacterial strategy without using traditional high-temperature, ultraviolet ray and antibiotics that cause side-effects.

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Fungicides chlorothanolin, azoxystrobin and folpet induce transcriptional alterations in genes encoding enzymes involved in oxidative phosphorylation and metabolism in honey bees (Apis mellifera) at sublethal concentrations

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Verena Christen, Jana Krebs, Karl Fent

Abstract

Fungicides are highly used for plant protection but their molecular and chronic effects are poorly known. Here, we analyse transcriptional effects in the brain of honey bees of three frequently applied fungicides, azoxystrobin, chlorothanolin and folpet, after oral exposure for 24, 48 and 72 h. Among transcripts assessed were genes encoding proteins for immune and hormone system regulation, oxidative phosphorylation, metabolism, and acetylcholine receptor alpha 1. Azoxystrobin and folpet induced minor alterations, including down-regulation of hbg-3 by azoxystrobin and induction of ndufb-7 by folpet. Chlorothanolin induced strong transcriptional down-regulation of genes encoding enzymes related to oxidative phosphorylation and metabolism, including cyp9q1cyp9q2 and cyp9q3acetylcholine receptor alpha 1 and hbg-3 and ilp-1, which are linked to hormonal regulation and behavioural transition of honey bees. Exposures to chlorothanolin in different seasonal times showed different responsiveness; responses were faster and often stronger in April than in June. Chlorothanolin caused the strongest effects and affected transcriptional abundance of genes related to energy production, metabolism and the endocrine system. Disturbed energy production may reduce foraging activity and hormonal dysregulation, such as the transition of nurse bees to foragers. Further analyses are needed to further substantiate potential adverse effects of chlorothanolin in bees on the physiological level.

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Coaggregation of bacterial communities in aerobic granulation and its application on the biodegradation of sulfolane

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Muhammad Faizan Khan, Linlong Yu, Joo Hwa Tay, Gopal Achari

Abstract

Aerobic granulation is regarded as the future technology for wastewater treatment that can replace conventional activated sludge. In this study, two approaches of forming sulfolane degrading aerobic granules (SDAG) were successfully developed and evaluated. These include adaptation of pre-grown granules to sulfolane environment and coaggregation of pre-grown granules with bacterial culture native to sulfolane contaminated site. The adaption method required a longer period to form robust SDAG compared to coaggregation method where degradation of sulfolane was observed within 24 h. Electronic images revealed dominant filamentous bacteria on the surface of granules while DNA analysis unveiled the complexity of the dynamic change of microbial community during aerobic granule formation. The rate of sulfolane degradation by coaggregated granules reduced as the concentration of carbon source increased, nevertheless, the rate increased with increased biomass. In addition, the presence of co-contaminants can slightly impact the ability of newly cultivated granules to degrade sulfolane. Finally, the stability and settleability of the new aerobic granules was investigated under different environmental conditions. About 30% of the aerobic granules were lost after 14 d of operation without any continuous supply of carbon sources. The surviving SDAGs continued to display an intact structure coupled with good settleability.

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Highly efficient and stable p-LaFeO3/n-ZnO heterojunction photocatalyst for phenol degradation under visible light irradiation

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Ting Ren, Zehua Jin, Jun Yang, Ruisheng Hu, Fu Zhao, Xiaojiao Gao, Chunxiao Zhao

Abstract

A series of catalysts with p-LaFeO3/n-ZnO heterostructure were designed and prepared by hydrothermal method. The structure, surface topographies, optical properties and interfacial interactions of these photocatalysts were analyzed by XRD, SEM, TEM, PL, Uv–vis DRS, XPS, COD, TOC etc., indicating that p-n heterojunction formed at the interface between p-LaFeO3 and n-ZnO, which enhanced the photocatalytic activity. Among them, the 20%-p-LaFeO3/n-ZnO composite exhibits the best activity for the phenol degradation under visible light. The superior photocatalytic activity of the heterojunction photocatalyst is mainly attributed to the formation of p-n heterojunction which leads to an efficient separation of photogenerated electron-hole pairs. Besides, the 20%-p-LaFeO3/n-ZnO heterojunction photocatalyst shows the excellent photocatalytic stability after 4 cycles. And from the free radical capture experiment, the degradation of phenol is dominated by the oxidation reaction of hydroxyl radicals and direct hole oxidation. What's more, certain intermediates were detected by HPLC and 3D-EEMs. Therefore, a photocatalytic mechanism of the 20%-p-LaFeO3/n-ZnO p-n heterojunction catalyst for phenol degradation under visible light irradiation was proposed.

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Effects of biochar amendments on antibiotic resistome of the soil and collembolan gut

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Jing Ding, Yue Yin, An-Qi Sun, Simon Bo Lassen, Gang Li, Dong Zhu, Xin Ke

Abstract

A diverse array of ARGs has been detected in the guts of soil fauna residing in farmland soil. Biochar has been widely used in farmland for soil remediation and improvement of soil quality; however, the effects of biochar amendment on the gut-associated ARGs of soil fauna remain unclear. In the present study, collembolans were cultivated in soils amended with 6 types of biochars. High-throughput qPCR was used to establish ARG profiles of the collembolan guts as well as the surrounding soils. A total of 73 and 162 subtypes of ARGs were detected in the collembolan guts and soils, respectively. Biochar amendment significantly altered the ARG compositions of the collembolan guts and soils, in a biochar quality-dependent manner. However, only manure-derived biochar, which contained elevated concentrations of heavy metals, increased the relative abundance of gut-associated ARGs. Changes in the gut microbial community, MGEs and biochar properties explained 84% of the total ARG variations in the collembolan guts. The findings of this study suggested that biochar properties should receive more attention, as high doses of heavy metals in biochar could increase the abundance of ARGs in collembolan guts, thereby contributing to the spread of ARGs in the environment through collembolan movement.

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Microbial antimonate reduction with a solid-state electrode as the sole electron donor: A novel approach for antimony bioremediation

Publication date: 5 September 2019

Source: Journal of Hazardous Materials, Volume 377

Author(s): Van Khanh Nguyen, Younghyun Park, Taeho Lee

Abstract

The anaerobic antimonate [Sb(V)] reduction with a solid-state electrode serving as the sole electron donor was demonstrated by employing a bioelectrochemical system. The highest Sb(V) reduction efficiency was observed at the biocathode potential of −0.7 V versus standard hydrogen electrode using a cathode potential range from −0.5 V to −1.1 V. The scanning electron microscopy and energy dispersive X-ray spectroscopy indicated that both amorphous and crystallized Sb2O3 were formed as products of Sb(V) reduction. The irreversible recovery of bioelectrochemical Sb(V), when the cathode potential deviated from the optimal potential, was explained through the alteration in microbial communities, which was further elucidated by the next-generation sequencing of 16S rRNA gene amplicons. Chryseobacterium koreense and Stenotrophomonas nitritireducens were the dominant species of microbial consortia at Sb(V)-reducing biocathodes. This study revealed a novel option for bioremediation of Sb at underground contaminated sites, where the delivery of organic electron donors is limited or ineffective.



Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480

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