Single gold-bridged nanoprobes for identification of single point DNA mutations

Single gold-bridged nanoprobes for identification of single point DNA mutations

Single gold-bridged nanoprobes for identification of single point DNA mutations, Published online: 19 February 2019; doi:10.1038/s41467-019-08769-y

The identification of single point mutations is an important step toward personalizing detection and treatment. Here the authors design a gold-bridged nanoparticle for sensing MutS affinities to point mutations, and compile an atlas of the affinity data for detecting BRCA1 mutations in cell lines.

from A via a.sfakia on Inoreader https://go.nature.com/2GQoCbr