Baseline Pancreatic Beta Cell Imaging After Pancreatic Transplantation Using Whole-Body 68Ga-DOTA-Exendin-4 PET/CT: A Spectrum of 2 Cases of Diabetes Mellitus

Whole pancreatic transplant and islet cells transplantation are currently available strategies aiming toward diabetes cure. Beta cell specific noninvasive functional imaging using novel PET radiotracers are now available and can be used for beta cell imaging and quantification. Herein we describe a spectrum of 2 cases demonstrating beta cell targeted imaging using 68Ga-DOTA-exendin-4 PET/CT in patients with diabetes after simultaneous pancreas-kidney transplantation. Received for publication February 4, 2018; revision accepted December 1, 2018. Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Conflicts of interest and sources of funding: none declared. Correspondence to: Aashish Gambhir, MBBS, DRM, DNB, Department of Nuclear Medicine and PET/CT, Apollo Hospitals, Chennai, Tamil Nadu 600006, India. E-mail: aashishgambhir61@gmail.com. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.

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