The Impact of Colloid Cyst Treatment on Neuro-cognition.

The Impact of Colloid Cyst Treatment on Neuro-cognition.

World Neurosurg. 2019 Jan 28;:

Authors: Roth J, Sela G, Andelman F, Nossek E, Elran H, Ram Z

Abstract
BACKGROUND: Colloid cysts (CC) have been associated with neurocognitive function (NCF) decline, both preoperatively and following resection. Factors such as local pressure on the fornix and hydrocephalus are thought to contribute to preoperative NCF decline. Potential cause of post-operative decline is thought to be forniceal injury during surgery. In the current series, we describe NCF outcomes amongst patients with CC, both non-operated and operated.
METHODS: 36 patients (23 operated, 13 non-operated) were included in this retrospective study. All patients underwent at least one NCF evaluation battery. Five of the 13 non-operated cases had follow up tests too. Of the 23 operated, 14 had both pre-and post-operative tests, 8 had early and late postoperative tests.
RESULTS: There was no significant difference in baseline NCF between non-operated and operated cases (as evaluated preoperatively). Non-operated patients had a stable NCF test over time. Patients that were operated showed a significant improvement after surgery in several NCF variables. There was no significant change in NCF between early and late postoperative evaluation. None of the operated patients had a postoperative NCF decline.
CONCLUSIONS: Patients with CC should undergo routine NCF testing with a standardized protocol, whether they are operated or followed. Surgery has a positive impact on NCF; however, it remains to be determined if the improvement is solely secondary to treatment of hydrocephalus, or to a reduction of local pressure on the fornices. It remains to be determined whether the surgical technique - i.e. endoscopic, interhemispheric, or transcortical, has an impact on NCF outcome.

PMID: 30703590 [PubMed - as supplied by publisher]

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