A Case of Primary Sellar Paraganglioma: Immunohistochemistry Resource and Review.

A Case of Primary Sellar Paraganglioma: Immunohistochemistry Resource and Review.

World Neurosurg. 2019 Jan 28;:

Authors: Lyne SB, Polster SP, Fidai S, Pytel P, Yamini B

Abstract
BACKGROUND: The differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Seldom is primary paraganglioma considered. Here we present a case of this unique pathology, review the relevant literature and compile a compendium of immunohistochemical characteristics for use as a resource.
CASE DESCRIPTION: A 73-year old female presented to the hospital with visual changes in her left hemifield. Non-contrasted head computer tomography (CT) demonstrated a large sellar mass with suprasellar extension and displacement of the optic chiasm (diameter of 3.1 cm). Magnetic resonance imaging was unobtainable due to an incompatible pacemaker. CT characterization was most consistent with a macroadenoma. Given the acute visual decline, surgical decompression via an endonasal transsphenoidal route was completed without complication. Histopathology revealed a diagnosis of paraganglioma. Following resection the patient's visual field deficit improved. CT body imaging was negative for a metastatic origin.
CONCLUSIONS: Paraganglioma is a rare but potential diagnosis when evaluating sellar masses.

PMID: 30703592 [PubMed - as supplied by publisher]

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