Orthobunyavirus spike architecture and recognition by neutralizing antibodies

Orthobunyavirus spike architecture and recognition by neutralizing antibodies

<i>Orthobunyavirus</i> spike architecture and recognition by neutralizing antibodies, Published online: 20 February 2019; doi:10.1038/s41467-019-08832-8

Orthobunyaviruses (OBVs) cause severe disease in humans and farm animals, but the molecular basis for infection is not fully understood. Here, the authors present crystal structures of free and antibody-bound OBV envelope glycoproteins and show that their domains enable efficient immunization in a mouse model.

from A via a.sfakia on Inoreader https://ift.tt/2T3gT0l