Unstable genomes promote inflammation

Unstable genomes promote inflammation

Unstable genomes promote inflammation, Published online: 20 February 2019; doi:10.1038/d41586-019-00510-5

Faulty DNA replication can make genomes unstable. It now seems that, in mice, severe disruption of DNA replication triggers inflammation in the placenta, and female embryos are more sensitive to this than are male ones.

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