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Fenestration of the lamina terminalis on the occurrence of shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage: a meta-analysis.
World Neurosurg. 2019 Feb 16;:
Authors: Mao J, Zhu Q, Ma Y, Lan Q, Cheng Y, Liu G
Abstract
BACKGROUND: Shunt-dependent hydrocephalus (SDH) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and affect its outcome significantly. Whether fenestration of the lamina terminalis (FLT) during anterior circulation aneurysm clipping for aSAH can decrease the occurrence of SDH is still controversial.
METHODS: Ovid, Pubmed database were retrieved by the following keywords "hydrocephalus" "subarachnoid hemorrhage" "aneurysm" "fenestration" and "lamina terminalis". The Cochran-Mantel-Haenszel test was used to compare overall incidence of SDH.
RESULTS: The literatures were searched, and 15 were included involving 2,839 patients. The overall incidence of SDH in fenestrated cohort was 11.4%, compared with 15.3% in non-fenestrated cohort (p=0.008). The relative risk of SDH in fenestrated cohort was 0.67 (95% CI 0.50-0.90).
CONCLUSIONS: This meta-analysis suggests that FLT during anterior circulation aneurysm clipping reduces the incidence of SDH. However, a well-designed, randomized controlled trial is needed to prove the efficacy of FLT to reduce SDH.
PMID: 30780038 [PubMed - as supplied by publisher]
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