Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7

Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7

Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7, Published online: 31 January 2019; doi:10.1038/s41467-019-08373-0

Rix7 is a type II AAA-ATPase that is required for the assembly of the large ribosomal subunit. Here the authors present the 4.5 Å cryo-EM structure of the Rix7 homohexamer with a polypeptide fragment bound in its central channel and provide insights into the function of Rix7 as a molecular unfoldase.

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