Regional Neck Control in Head and Neck Squamous Cell Carcinoma with Positive Neck Disease Treated with Primary Chemoradiation

The treatment of squamous cell carcinomas of the head and neck (HNSCC) is multidisciplinary. Chemoradiation has become an integral part of the treatment process in managing metastatic neck disease. Randomized controlled trials and meta-analyses have demonstrated major improvements not only in loco-regional tumor control, but also in terms of survival when chemotherapy is added to radiotherapy. In clinical practice, this has translated into a reduction in the number of recurrent neck disease needing salvage surgery.

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