Quantitatively Excessive Normal Tissue Toxicity and Poor Target coverage in the lung cancer post-operative radiation Meta-Analysis

In this dosimetric study, the outdated techniques used in postoperative radiation proto cols included in the PORT meta-analysis provided inadequate target coverage with excessive radiation doses to organs at risk. We provided quantitative evidence for one of the explanations behind the detrimental effect noticed in the meta-analysis, invalidating its finding in the modern era of radiation planning and delivery.

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