Presence of Even a Small Ground Glass Component in Lung Adenocarcinoma Predicts Better Survival

The impact of having a small ground glass opacity component in an otherwise mostly solid lung adenocarcinoma on prognosis was evaluated using Kaplan-Meier and Cox analyses of 123 patients who underwent lobar or sublobar resection of clinical N0 lung adenocarcinomas without induction therapy. Patients with tumors that had a minor ground glass component that comprised less than 25% of the overall tumor size had less pathological upstaging and dramatically better 5-year overall survival compared to patients who had a 100% solid cancer.

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