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Τετάρτη 5 Ιουλίου 2017

Co-circulation of all four dengue virus serotypes: First report from Odisha

Baijayantimala Mishra, Jyotirmayee Turuk, Subhra Jyoti Sahu, Atul Khajuria, Subrat Kumar, Anupam Dey, Ashok Kumar Praharaj

Indian Journal of Medical Microbiology 2017 35(2):293-295

The present report describes the detection of co-circulation of all the four dengue serotypes along with rarely detected dengue viruses (DENVs)-4 for the first time in Odisha. One hundred and forty-eight blood samples were tested for dengue NS1 antigen ELISA and IgM antibody (Ab), and twenty early samples were subjected for type-specific multiplex reverse transcription-polymerase chain reaction (RT-PCR). Twenty-three samples found positive for dengue NS1 and/or IgM Ab; five were positive by RT-PCR. DENV-4 was detected in one sample, DENV-2 in two and 2 were co-infected with DENV-1 and 3. Co-circulation of all four dengue serotypes in Eastern India emphasises the need of molecular monitoring of circulating DENV serotypes.

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