Preclinical and clinical studies of Coriolus versicolor polysaccharopeptide as an immunotherapeutic in China.

Authors: Chang Y, Zhang M, Jiang Y, Liu Y, Luo H, Hao C, Zeng P, Zhang L Abstract Conventional cancer treatments include surgery, chemotherapy, and radiation therapy. In recent years, immunotherapy in cancer care has been gaining momentum. Interestingly, an immunotherapeutic regime that employs polysaccharopeptide (PSP), a unique peptide-containing polysaccharide isolated from Coriolus versicolor, has already become a routine clinical practice in Japan since 1977 and in China since 1987. Coriolus versicolor is one of the most well-known traditional food and medicinal mushrooms in China for thousands of years. Medically used PSP is mostly obtained from the extraction of cultured Coriolus versicolor mycelia where β-glucan is the major component. PSP has proven beneficial to survival...

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