Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine

Tissue-resident Eomes⁺ NK cells are the major innate lymphoid cell population in human infant intestine

Tissue-resident Eomes⁺ NK cells are the major innate lymphoid cell population in human infant intestine, Published online: 28 February 2019; doi:10.1038/s41467-018-08267-7

Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in adult intestines.

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