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Σάββατο 12 Ιανουαρίου 2019

Neuromuscular complications of immune checkpoint inhibitors.

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Neuromuscular complications of immune checkpoint inhibitors.

Presse Med. 2018 Nov - Dec;47(11-12 Pt 2):e253-e259

Authors: Psimaras D

Abstract
Immune checkpoint inhibitors have been increasingly used in patients with various cancers. Despite favourable oncological outcomes these treatments have also been associated with immune-related adverse events. Neurological irAE are rare but potentially severe and neuromuscular complications are the most common. This is a new group of neurologic complications of systemic anticancer therapies, often responsive to immune-modulating therapies. Early recognition and treatment are crucial for timely improvement of functional outcome and requires a multidisciplinary approach.

PMID: 30413332 [PubMed - indexed for MEDLINE]



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