18F-Choline PET/CT in Leptomeningeal Breast Cancer Metastases

We describe a case of 47-year-old woman affected by human epidermal growth factor receptor-2–positive breast cancer with a diffuse leptomeningeal carcinomatosis. An intense uptake of 18F-choline was reported at fused PET/MRI images in the brain, compatible with a diffuse leptomeningeal disease. This case highlights that 18F-choline PET would be used for the identification of leptomeningeal involvement in patients affected by breast cancer, as a support of MRI images. Received for publication July 25, 2018; revision accepted October 21, 2018. Conflicts of interest and sources of funding: none declared. Correspondence to: Laura Evangelista, MD, PhD, Nuclear Medicine and Molecular Imaging Unit, Veneto Institute of Oncology IOV–IRCCS, Via Gattamelata 64, 35128 Padova, Italy. E-mail: laura.evangelista@iov.veneto.it. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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